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Cheap flights from Southampton to Santiago from £1,007

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SCL
2 Jun — 9 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Santiago
Explore the most affordable flight options available from Southampton to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 May 2026.

Sun 8/1117:30
SOU
-
SCL
2 stops41h 10m
Delta
Sun 15/1123:10
SCL
-
SOU
2 stops30h 00m
Delta
Deal found 29/4£1,007
Sun 8/1117:30
SOU
-
SCL
2 stops41h 10m
Delta
Wed 18/1123:10
SCL
-
SOU
2 stops54h 40m
Delta
Deal found 29/4£1,057
Sun 8/1117:30
SOU
-
SCL
2 stops41h 10m
Delta
Sat 14/1123:10
SCL
-
SOU
2 stops38h 50m
Delta
Deal found 29/4£1,067
Mon 2/1117:30
SOU
-
SCL
2 stops41h 10m
Delta
Tue 17/1123:10
SCL
-
SOU
2 stops53h 55m
Delta
Deal found 29/4£1,107
Mon 2/1117:30
SOU
-
SCL
2 stops65h 10m
Delta
Wed 18/1123:10
SCL
-
SOU
2 stops54h 40m
Delta
Deal found 29/4£1,157
Tue 16/617:20
SOU
-
SCL
2 stops20h 25m
KLM
Tue 23/610:15
SCL
-
SOU
2 stops25h 35m
KLM
Deal found 2/5£1,192
Fri 6/1117:30
SOU
-
SCL
2 stops41h 10m
Delta
Thu 19/1123:10
SCL
-
SOU
2 stops38h 50m
Delta
Deal found 29/4£1,231
Fri 6/1117:30
SOU
-
SCL
2 stops41h 10m
Delta
Wed 18/1123:10
SCL
-
SOU
2 stops54h 40m
Delta
Deal found 29/4£1,281
Tue 16/617:20
SOU
-
SCL
3 stops36h 40m
Multiple Airlines
Tue 23/605:00
SCL
-
SOU
3 stops27h 40m
Multiple Airlines
Deal found 2/5£1,292

Find flight deals from Southampton to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 3 May 2026.

Round-trip from

£1,192

Popular in

December

Cheapest in

June

Average price

£902
KLM
  • KLM
  • 16/6-23/6
  • 4 total stops
  • 46h 00m total
  • Southampton to Santiago
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (£15 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 3 May 2026.
Use the filters below to find and compare flights from Southampton to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Tue 16/6

17:20-08:45

2 stops20h 25m

Santiago Arturo Merino Benitez

Tue 23/6

10:15-16:50

2 stops25h 35m

£1,192

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Tue 16/6

17:20-23:20

2 stops35h 00m

Santiago Arturo Merino Benitez

Tue 23/6

06:40-16:50

3 stops29h 10m

£1,529

Flights are sorted by cheapest return flights first.

Deals found on 2/5

Sorted by cheapest first

Best time to book a flight from Southampton to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 3 May 2026.
See what other customers who have flown with KLM from Southampton to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,509 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Food

7.3

Comfort

7.7

Crew

8.4

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7.8
Good
1,509 reviews
KLM
7.8
Good
1,509 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Food

7.3

Comfort

7.7

Crew

8.4

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from Southampton to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Southampton to Santiago that include hotel bookings?

    Yes. In addition to deals on Southampton to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Santiago.

  • Can I find deals for business class flights from Southampton to Santiago?

    Yes. Cheapflights offers flight deals from Southampton to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Southampton to Santiago

Discover the top airline that operate flights from Southampton to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 3 May 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest£1,184Average£1,315FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to Santiago?

Deals for Southampton to Santiago flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Santiago?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Santiago for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Santiago with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Southampton to Santiago, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Southampton to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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