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£275+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 30/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
15 Feb — 22 Feb1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 16 January 2026.

Cheapest airline

Air Panama

Good round-trip deal

£193 or less

Good one-way deal

£104 or less
On average, Air Panama currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of £197).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 16 January 2026.

Sat 14/221:45
PTY
-
BRU
1 stop37h 35m
Turkish Airlines
Thu 26/211:35
BRU
-
PTY
2 stops35h 30m
Turkish Airlines
Deal found 15/1£551
Thu 2/420:25
PTY
-
BRU
1 stop14h 15m
Air Europa
Sun 24/510:45
BRU
-
PTY
1 stop14h 55m
Air Europa
Deal found 15/1£553
Thu 2/420:25
PTY
-
BRU
1 stop14h 15m
Air Europa
Mon 25/518:55
BRU
-
PTY
1 stop30h 45m
Air Europa
Deal found 15/1£561
Fri 3/420:25
PTY
-
BRU
1 stop14h 45m
Air Europa
Thu 28/510:45
BRU
-
PTY
1 stop14h 55m
Air Europa
Deal found 15/1£576
Mon 2/321:45
PTY
-
BRU
1 stop37h 35m
Turkish Airlines
Tue 17/318:20
BRU
-
PTY
1 stop31h 30m
Turkish Airlines
Deal found 15/1£585
Mon 6/420:25
PTY
-
BRU
1 stop14h 15m
Air Europa
Sun 24/510:45
BRU
-
PTY
1 stop14h 55m
Air Europa
Deal found 15/1£600
Sat 4/422:20
PTY
-
BRU
1 stop32h 05m
Turkish Airlines
Tue 26/518:55
BRU
-
PTY
1 stop32h 30m
Turkish Airlines
Deal found 15/1£606
Mon 2/321:45
PTY
-
BRU
1 stop30h 50m
Turkish Airlines
Sun 15/315:15
BRU
-
PTY
1 stop34h 35m
Turkish Airlines
Deal found 15/1£607
Sun 5/420:05
PTY
-
BRU
1 stop34h 20m
Turkish Airlines
Sun 24/511:10
BRU
-
PTY
1 stop40h 15m
Turkish Airlines
Deal found 15/1£614
Mon 9/218:45
PTY
-
CDG
1 stop16h 25m
KLM
Sun 1/320:45
CDG
-
PTY
1 stop25h 45m
KLM
Deal found 14/1£618
Tue 3/318:45
PTY
-
BRU
1 stop21h 25m
Turkish Airlines
Mon 16/311:35
BRU
-
PTY
2 stops35h 30m
Turkish Airlines
Deal found 15/1£623
Sat 4/422:20
PTY
-
DUS
1 stop27h 40m
Turkish Airlines
Sun 24/514:55
DUS
-
PTY
1 stop36h 30m
Turkish Airlines
Deal found 15/1£632

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 16 January 2026. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 7/4

20:25-17:40

1 stop14h 15m

Brussels Bruxelles-National

Thu 28/5

10:45-18:40

1 stop14h 55m

£576

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 7/4

20:25-17:40

1 stop14h 15m

Brussels Bruxelles-National

Wed 27/5

10:45-18:40

1 stop14h 55m

£576

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 7/4

20:25-17:40

1 stop14h 15m

Brussels Bruxelles-National

Sun 24/5

10:45-18:40

1 stop14h 55m

£576

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 3/4

20:25-17:40

1 stop14h 15m

Brussels Bruxelles-National

Wed 27/5

10:45-18:40

1 stop14h 55m

£576

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 3/4

20:25-18:10

1 stop14h 45m

Brussels Bruxelles-National

Thu 28/5

10:45-18:40

1 stop14h 55m

£576

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 4/3

21:45-14:15

1 stop34h 30m

Brussels Bruxelles-National

Tue 17/3

18:20-19:50

1 stop31h 30m

£585

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 3/4

20:25-18:10

1 stop14h 45m

Brussels Bruxelles-National

Mon 25/5

18:55-18:40

1 stop30h 45m

£585

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 7/3

21:45-14:15

1 stop34h 30m

Brussels Bruxelles-National

Thu 19/3

11:35-17:05

2 stops35h 30m

£593

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 8/3

18:45-14:15

1 stop37h 30m

Brussels Bruxelles-National

Tue 17/3

18:20-19:50

1 stop31h 30m

£593

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 2/3

21:45-10:35

1 stop30h 50m

Brussels Bruxelles-National

Thu 19/3

11:35-17:05

2 stops35h 30m

£593

Flights are sorted by cheapest return flights first.

Deals found on 13/1

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to Heathrow. Price data was last updated on 9 January 2026.

Booking 42 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City?

Currently, February is the cheapest month in which you can book a flight from Panama City (average of £491). Flying from Panama City in August will prove the most costly (average of £770). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

Many airlines operate round-trip flights from Panama City: Air France, United Airlines. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £100
Air Panama
Air Panama
From £114
Avianca
Avianca
From £139
Air France
Air France
From £671

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Sao Paulo (266 flights per day), San José (130 flights per day) and Miami (125 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From £125
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £117
Bocas Del Toro
Bocas Del Toro
From £97
Amsterdam Schiphol
Amsterdam Schiphol
From £856

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Bocas Del Toro, with prices starting at £97. Explore other affordable destinations below.

Bocas Del Toro
Bocas Del Toro
From £97
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £100
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £109
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £117

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama City, such as Air France and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,522 reviews
Check prices

Crew

8.1

Entertainment

7.0

Overall

7.4

Food

7.0

Comfort

7.4

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

Alpha Amadu,Dec 2025

CKY - CDG

Super calm and deliberate, staff are exceptionally down to detail
Air France
7.4
Good
1,522 reviews
Air France
7.4
Good
1,522 reviews
Check prices

Crew

8.1

Entertainment

7.0

Overall

7.4

Food

7.0

Comfort

7.4

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

Alpha Amadu,Dec 2025

CKY - CDG

Super calm and deliberate, staff are exceptionally down to detail
United Airlines
7.4
Good
9,164 reviews
Air France
7.4
Good
1,522 reviews
Check prices

Crew

8.1

Entertainment

7.0

Overall

7.4

Food

7.0

Comfort

7.4

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

Alpha Amadu,Dec 2025

CKY - CDG

Super calm and deliberate, staff are exceptionally down to detail

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 16 January 2026.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, David. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £100 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for £531 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Wingo, Copa Airlines, and Air Panama have the cheapest prices from Panama City. Wingo flights from Panama City to Medellín Jose Maria Cordova Intl (£53), Copa Airlines flights from Panama City to Bogotá El Dorado (£100), and Air Panama flights from Panama City to Bocas Del Toro (£114).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Madrid from £1,098
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £1,209
    Panama City Tocumen Intl to Amsterdam from £2,045

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently February; with August being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to London from £599 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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