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£112+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
27 déc. — 3 janv.1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 27 novembre 2025.

Cheapest airline

Air Panama

Good round-trip deal

£201 or less

Good one-way deal

£68 or less
On average, Air Panama currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of £175).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 27 novembre 2025.

sam. 13/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
sam. 20/1204:26SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 25/11£221
jeu. 15/111:34PTY - SAP
Nonstop2h 06mCopa Airlines
jeu. 22/113:52SAP - PTY
Nonstop2h 09mCopa Airlines
Deal found 25/11£237
mar. 17/322:19PTY - SAP
Nonstop2h 10mCopa Airlines
mar. 24/313:50SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 24/11£254
mer. 31/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
jeu. 1/113:52SAP - PTY
Nonstop2h 09mCopa Airlines
Deal found 26/11£260
sam. 13/1219:50PTY - SAP
1 stop13h 40mMultiple Airlines
dim. 21/1213:53SAP - PTY
Nonstop2h 08mMultiple Airlines
Deal found 25/11£295
sam. 13/1219:50PTY - SAP
1 stop13h 40mAvianca
dim. 21/1209:25SAP - PTY
1 stop8h 30mAvianca
Deal found 25/11£316
lun. 6/422:15PTY - BRU
1 stop28h 55mTurkish Airlines
mer. 27/507:20BRU - PTY
1 stop20h 00mTurkish Airlines
Deal found 25/11£594
dim. 5/420:10PTY - BRU
1 stop34h 15mTurkish Airlines
mar. 26/511:10BRU - PTY
1 stop40h 10mTurkish Airlines
Deal found 25/11£602
sam. 14/222:05PTY - BRU
1 stop18h 15mKLM
jeu. 26/208:05BRU - PTY
1 stop14h 25mKLM
Deal found 25/11£603
lun. 6/422:15PTY - BRU
1 stop36h 35mTurkish Airlines
ven. 29/511:10BRU - PTY
1 stop40h 10mTurkish Airlines
Deal found 25/11£617
mer. 8/422:15PTY - BRU
1 stop32h 10mTurkish Airlines
dim. 31/516:15BRU - PTY
1 stop35h 05mTurkish Airlines
Deal found 25/11£618
dim. 5/420:10PTY - BRU
1 stop31h 00mTurkish Airlines
dim. 31/514:25BRU - PTY
1 stop36h 55mTurkish Airlines
Deal found 25/11£625

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 27 novembre 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

sam. 13/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

dim. 21/12

13:53-17:01

Nonstop2h 08m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

sam. 13/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

jeu. 8/1

04:25-07:39

Nonstop2h 14m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

jeu. 25/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

jeu. 1/1

13:52-17:01

Nonstop2h 09m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

ven. 26/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

ven. 2/1

13:52-17:01

Nonstop2h 09m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

mar. 16/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

mer. 17/12

13:53-17:01

Nonstop2h 08m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

mar. 16/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

dim. 28/12

13:53-17:01

Nonstop2h 08m

£221

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

jeu. 15/1

11:34-12:40

Nonstop2h 06m

San Pedro Sula Ramon Villeda

jeu. 22/1

13:52-17:01

Nonstop2h 09m

£237

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

mar. 17/3

22:19-23:29

Nonstop2h 10m

San Pedro Sula Ramon Villeda

mar. 24/3

13:50-17:03

Nonstop2h 13m

£254

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

lun. 6/4

22:15-10:10

1 stop28h 55m

Brussels Bruxelles-National

mer. 27/5

07:20-20:20

1 stop20h 00m

£594

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

sam. 11/4

22:15-17:50

1 stop36h 35m

Brussels Bruxelles-National

mar. 26/5

11:10-20:20

1 stop40h 10m

£594

Flights are sorted by cheapest return flights first.

Deals found on 25/11

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to Heathrow. Price data was last updated on 21 November 2025.

Booking 3 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City?

Currently, December is the cheapest month in which you can book a flight from Panama City (average of £489). Flying from Panama City in August will prove the most costly (average of £782). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

Many airlines operate round-trip flights from Panama City: KLM, Air France, United Airlines. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £125
Air Panama
Air Panama
From £116
Wingo
Wingo
From £75
Avianca
Avianca
From £124

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Sao Paulo (234 flights per day), San José (158 flights per day) and Guatemala City (108 flights per day).

Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £68
Bocas Del Toro
Bocas Del Toro
From £104
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £89
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £57

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Medellín Jose Maria Cordova Intl, with prices starting at £57. Explore other affordable destinations below.

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £57
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £68
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £89
Bocas Del Toro
Bocas Del Toro
From £104

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama City, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Boarding

7.8

Comfort

7.6

Crew

8.4

Entertainment

7.1

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,423 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Boarding

7.8

Comfort

7.6

Crew

8.4

Entertainment

7.1

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7.4
Good
1,498 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Boarding

7.8

Comfort

7.6

Crew

8.4

Entertainment

7.1

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7.4
Good
9,050 reviews
KLM
7.7
Good
1,423 reviews
Check prices

Food

7.2

Boarding

7.8

Comfort

7.6

Crew

8.4

Entertainment

7.1

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 27 novembre 2025.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, Guatemala City. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £89 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for £545 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Wingo, Air Panama, and Avianca have the cheapest prices from Panama City. Wingo flights from Panama City to Bogotá El Dorado (£75), Air Panama flights from Panama City to Bocas Del Toro (£116), and Avianca flights from Panama City to Managua Augusto C Sandino (£124).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Madrid from £1,115
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £1,228
    Panama City Tocumen Intl to Amsterdam from £2,077

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently December; with August being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to San Pedro Sula from £216 round trip
    Travel from Panama City to London from £590 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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