£113+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — SAP
2 Dec — 9 Dec1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 2 November 2025.

Cheapest airline

Wingo

Good round-trip deal

£299 or less

Good one-way deal

£73 or less
On average, Wingo currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of £109).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 2 November 2025.

Fri 28/1111:34PTY - SAP
Nonstop2h 14mCopa Airlines
Sun 30/1104:26SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 2/11£222
Tue 25/1111:34PTY - SAP
Nonstop2h 14mCopa Airlines
Mon 2/204:28SAP - PTY
Nonstop2h 11mCopa Airlines
Deal found 31/10£238
Wed 11/211:34PTY - SAP
Nonstop2h 11mCopa Airlines
Mon 16/213:55SAP - PTY
Nonstop2h 06mCopa Airlines
Deal found 1/11£255
Wed 18/221:45PTY - LHR
1 stop19h 40mTurkish Airlines
Tue 24/222:35LHR - PTY
1 stop23h 30mTurkish Airlines
Deal found 1/11£620
Tue 3/218:45PTY - LHR
1 stop21h 20mTurkish Airlines
Tue 10/222:35LHR - PTY
1 stop26h 15mTurkish Airlines
Deal found 1/11£622
Mon 9/321:45PTY - LGW
1 stop19h 45mTurkish Airlines
Mon 30/307:00LGW - PTY
1 stop19h 20mTurkish Airlines
Deal found 30/10£626
Sat 14/221:45PTY - BRU
1 stop30h 50mTurkish Airlines
Thu 26/207:50BRU - PTY
2 stops39h 15mTurkish Airlines
Deal found 2/11£627
Sun 8/218:45PTY - LGW
1 stop22h 50mTurkish Airlines
Wed 18/217:05LGW - PTY
1 stop29h 00mTurkish Airlines
Deal found 2/11£629
Mon 17/1121:45PTY - LHR
1 stop19h 40mTurkish Airlines
Sun 31/513:15LHR - PTY
1 stop37h 05mTurkish Airlines
Deal found 2/11£629
Sat 14/222:05PTY - BRU
1 stop18h 15mKLM
Thu 26/206:15BRU - PTY
1 stop16h 15mKLM
Deal found 1/11£629
Tue 10/318:45PTY - LGW
1 stop22h 50mTurkish Airlines
Tue 24/317:05LGW - PTY
1 stop31h 45mTurkish Airlines
Deal found 1/11£633
Sun 8/218:45PTY - BRU
1 stop21h 25mTurkish Airlines
Thu 12/211:35BRU - PTY
2 stops35h 30mTurkish Airlines
Deal found 1/11£636

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 2 November 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

San Pedro Sula

Route

Depart

Return

Price

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 28/11

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 30/11

04:26-07:39

Nonstop2h 13m

£222

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Wed 10/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Tue 16/12

13:53-17:01

Nonstop2h 08m

£222

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 26/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 4/1

13:52-17:01

Nonstop2h 09m

£222

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Mon 15/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Thu 15/1

04:25-07:39

Nonstop2h 14m

£238

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 25/11

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Tue 3/2

13:55-17:01

Nonstop2h 06m

£238

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 9/1

11:34-12:40

Nonstop2h 06m

San Pedro Sula Ramon Villeda

Thu 22/1

04:25-07:39

Nonstop2h 14m

£238

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 14/2

21:45-17:20

1 stop37h 35m

Brussels Bruxelles-National

Thu 26/2

07:50-17:05

2 stops39h 15m

£627

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 14/2

22:05-22:20

1 stop18h 15m

Brussels Bruxelles-National

Thu 26/2

06:15-16:30

1 stop16h 15m

£629

Panama CityLondon

PTY - LGW

PTYLGW

Panama City Tocumen Intl

Wed 12/11

21:45-22:35

1 stop19h 50m

London Gatwick

Wed 26/11

06:25-17:05

2 stops39h 40m

£642

Panama CityLondon

PTY - LGW

PTYLGW

Panama City Tocumen Intl

Mon 9/3

21:45-16:10

1 stop37h 25m

London Gatwick

Mon 30/3

10:50-18:30

2 stops37h 40m

£645

Flights are sorted by cheapest return flights first.

Deals found on 1/11

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to San Pedro Sula. Price data was last updated on 31 October 2025.

Booking 74 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City?

Currently, November is the cheapest month in which you can book a flight from Panama City (average of £109). Flying from Panama City in January will prove the most costly (average of £220). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Sao Paulo (248 flights per day), San José (153 flights per day) and Bogotá (92 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From £109
Frankfurt am Main
Frankfurt am Main
From £258
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £68
New York
New York
From £1,106

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Cartagena Rafael Nunez, with prices starting at £68. Explore other affordable destinations below.

Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £68
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £91
Bogotá El Dorado
Bogotá El Dorado
From £109
Simpson Bay Princess Juliana
Simpson Bay Princess Juliana
From £240

Browse thousands of different options on Cheapflights for your next trip

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 2 November 2025.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, Cartagena. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £91 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for £580 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Wingo, Air Panama, and Avianca have the cheapest prices from Panama City. Wingo flights from Panama City to Bogotá El Dorado (£76), Air Panama flights from Panama City to Bocas Del Toro (£115), and Avianca flights from Panama City to Armenia El Eden (£125).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Madrid from £1,119
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £1,232
    Panama City Tocumen Intl to Amsterdam from £2,084

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently November; with January being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to San Pedro Sula from £217 round trip
    Travel from Panama City to London from £572 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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