Find flights
Airlines

£82+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
20 Dec — 27 Dec1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 20 November 2025.

Cheapest airline

Wingo

Good round-trip deal

£300 or less

Good one-way deal

£73 or less
On average, Wingo currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of £110).
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Panama City Tocumen Intl.
Search Deals

Find flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 20 November 2025.

Tue 10/207:31PTY - GUA
Nonstop2h 24mCopa Airlines
Fri 13/204:24GUA - PTY
Nonstop2h 26mCopa Airlines
Deal found 18/11£149
Sun 1/202:55PTY - GUA
1 stop11h 05mAvianca
Thu 12/209:30GUA - PTY
1 stop6h 25mAvianca
Deal found 18/11£152
Wed 4/217:50PTY - GUA
1 stop8h 50mAvianca
Sun 15/209:30GUA - PTY
1 stop6h 25mAvianca
Deal found 18/11£153
Tue 3/219:50PTY - GUA
1 stop4h 20mAvianca
Sun 15/209:30GUA - PTY
1 stop6h 25mAvianca
Deal found 18/11£154
Fri 6/210:10PTY - GUA
Nonstop2h 26mCopa Airlines
Thu 12/206:24GUA - PTY
1 stop3h 45mCopa Airlines
Deal found 18/11£155
Sun 11/121:45PTY - GUA
Nonstop2h 26mCopa Airlines
Fri 16/107:13GUA - PTY
Nonstop2h 23mCopa Airlines
Deal found 18/11£156
Sat 7/211:25PTY - GUA
1 stop7h 25mAvianca
Mon 9/209:30GUA - PTY
1 stop6h 25mAvianca
Deal found 18/11£159
Sun 8/211:25PTY - GUA
1 stop7h 25mAvianca
Tue 10/209:30GUA - PTY
1 stop6h 25mAvianca
Deal found 18/11£160
Sat 14/208:40PTY - GUA
1 stop14h 00mCopa Airlines
Mon 16/202:26GUA - PTY
Nonstop2h 29mCopa Airlines
Deal found 18/11£162
Wed 4/209:45PTY - GUA
1 stop8h 55mMultiple Airlines
Tue 10/204:24GUA - PTY
Nonstop2h 26mMultiple Airlines
Deal found 17/11£174
Mon 2/219:50PTY - GUA
1 stop4h 20mMultiple Airlines
Tue 10/204:24GUA - PTY
Nonstop2h 26mMultiple Airlines
Deal found 17/11£175
Fri 5/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
Mon 8/1213:53SAP - PTY
Nonstop2h 08mCopa Airlines
Deal found 19/11£223

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 20 November 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Tue 17/2

08:11-09:34

Nonstop2h 23m

Guatemala City La Aurora

Sun 22/2

06:24-11:09

1 stop3h 45m

£149

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Tue 13/1

10:25-11:51

Nonstop2h 26m

Guatemala City La Aurora

Sat 17/1

06:24-11:09

1 stop3h 45m

£149

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Thu 4/12

08:11-09:34

Nonstop2h 23m

Guatemala City La Aurora

Tue 9/12

16:28-19:55

Nonstop2h 27m

£149

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Thu 29/1

08:11-09:34

Nonstop2h 23m

Guatemala City La Aurora

Mon 2/2

04:24-07:50

Nonstop2h 26m

£149

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Thu 5/2

10:10-11:36

Nonstop2h 26m

Guatemala City La Aurora

Thu 12/2

06:24-11:09

1 stop3h 45m

£149

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Tue 10/2

18:34-21:40

1 stop4h 06m

Guatemala City La Aurora

Sat 14/2

16:27-19:51

Nonstop2h 24m

£149

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Tue 27/1

07:55-21:40

1 stop14h 45m

Guatemala City La Aurora

Mon 2/2

04:24-07:50

Nonstop2h 26m

£155

Panama CityGuatemala City

PTY - GUA

PTYGUA

Panama City Tocumen Intl

Fri 13/2

07:31-08:55

Nonstop2h 24m

Guatemala City La Aurora

Wed 18/2

06:24-11:09

1 stop3h 45m

£193

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 12/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 11/1

04:25-07:39

Nonstop2h 14m

£223

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Sat 13/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Thu 8/1

04:25-07:39

Nonstop2h 14m

£223

Flights are sorted by cheapest return flights first.

Deals found on 18/11

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to Heathrow. Price data was last updated on 14 November 2025.

Booking 3 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City?

Currently, December is the cheapest month in which you can book a flight from Panama City (average of £492). Flying from Panama City in August will prove the most costly (average of £787). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

Many airlines operate round-trip flights from Panama City: Air France, United Airlines, KLM. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £126
Wingo
Wingo
From £76
Air Panama
Air Panama
From £117
Avianca
Avianca
From £125

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Sao Paulo (260 flights per day), San José (154 flights per day) and Guatemala City (108 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From £109
Frankfurt am Main
Frankfurt am Main
From £259
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £69
New York
New York
From £1,110

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Cartagena Rafael Nunez, with prices starting at £69. Explore other affordable destinations below.

Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £69
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £91
Bogotá El Dorado
Bogotá El Dorado
From £109
Simpson Bay Princess Juliana
Simpson Bay Princess Juliana
From £241

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama City, such as KLM, Air France, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,412 reviews
Check prices

Comfort

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,412 reviews
KLM
7.7
Good
1,412 reviews
Check prices

Comfort

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Air France
7.4
Good
1,493 reviews
KLM
7.7
Good
1,412 reviews
Check prices

Comfort

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7.4
Good
9,027 reviews
KLM
7.7
Good
1,412 reviews
Check prices

Comfort

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 20 November 2025.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, Guatemala City. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £91 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for £582 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Wingo, Air Panama, and Avianca have the cheapest prices from Panama City. Wingo flights from Panama City to Bogotá El Dorado (£76), Air Panama flights from Panama City to Bocas Del Toro (£117), and Avianca flights from Panama City to Armenia El Eden (£125).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Madrid from £1,123
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £1,237
    Panama City Tocumen Intl to Amsterdam from £2,092

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently December; with August being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to San Pedro Sula from £217 round trip
    Travel from Panama City to London from £603 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.