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£220+ Cheap flights from Panama City

This is the cheapest return flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — LHR
3 Jan — 10 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 4 December 2025.

Cheapest airline

Air Panama

Good round-trip deal

£136 or less

Good one-way deal

£57 or less
On average, Air Panama currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of £173).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 4 December 2025.

Fri 26/1222:19PTY - SAP
Nonstop2h 14mCopa Airlines
Sun 28/1204:26SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 3/12£220
Fri 9/111:34PTY - SAP
Nonstop2h 06mCopa Airlines
Wed 21/113:52SAP - PTY
Nonstop2h 09mCopa Airlines
Deal found 1/12£236
Thu 5/311:34PTY - SAP
Nonstop2h 11mCopa Airlines
Sun 8/313:50SAP - PTY
Nonstop2h 13mCopa Airlines
Deal found 3/12£252
Tue 23/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
Mon 12/113:52SAP - PTY
Nonstop2h 09mCopa Airlines
Deal found 3/12£257
Mon 15/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
Sun 28/1213:53SAP - PTY
Nonstop2h 08mCopa Airlines
Deal found 2/12£312
Wed 20/511:34PTY - SAP
Nonstop2h 13mCopa Airlines
Sun 24/513:49SAP - PTY
Nonstop2h 12mCopa Airlines
Deal found 2/12£601
Sat 14/222:05PTY - BRU
1 stop18h 15mKLM
Thu 26/214:45BRU - PTY
1 stop31h 45mKLM
Deal found 1/12£604
Mon 13/418:50PTY - BRU
1 stop29h 45mKLM
Sat 25/410:25BRU - PTY
1 stop13h 25mKLM
Deal found 1/12£634
Mon 15/1211:34PTY - SAP
Nonstop2h 14mCopa Airlines
Thu 15/104:25SAP - PTY
Nonstop2h 14mCopa Airlines
Deal found 2/12£641
Mon 13/422:15PTY - BRU
1 stop40h 10mTurkish Airlines
Sat 25/411:10BRU - PTY
2 stops38h 20mTurkish Airlines
Deal found 1/12£664
Wed 18/222:05PTY - LHR
1 stop13h 55mKLM
Thu 5/315:45LHR - PTY
1 stop29h 45mKLM
Deal found 2/12£667
Sat 31/115:20PTY - LHR
1 stop15h 20mMultiple Airlines
Sun 8/206:30LHR - PTY
1 stop15h 00mMultiple Airlines
Deal found 1/12£673

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 4 December 2025. In the last 7 days, Cheapflights users made a total of 858,174 searches

Fly to

Heathrow

Route

Depart

Return

Price

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 26/12

22:19-23:33

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 28/12

04:26-07:39

Nonstop2h 13m

£220

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Fri 9/1

11:34-12:40

Nonstop2h 06m

San Pedro Sula Ramon Villeda

Wed 21/1

13:52-17:01

Nonstop2h 09m

£236

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Thu 5/3

11:34-12:45

Nonstop2h 11m

San Pedro Sula Ramon Villeda

Sun 8/3

13:50-17:03

Nonstop2h 13m

£252

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Tue 23/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Mon 12/1

13:52-17:01

Nonstop2h 09m

£257

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Mon 15/12

11:34-12:48

Nonstop2h 14m

San Pedro Sula Ramon Villeda

Sun 28/12

13:53-17:01

Nonstop2h 08m

£312

Panama CitySan Pedro Sula

PTY - SAP

PTYSAP

Panama City Tocumen Intl

Wed 20/5

11:34-12:47

Nonstop2h 13m

San Pedro Sula Ramon Villeda

Sun 24/5

13:49-17:01

Nonstop2h 12m

£601

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 14/2

22:05-22:20

1 stop18h 15m

Brussels Bruxelles-National

Thu 26/2

14:45-16:30

1 stop31h 45m

£604

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 13/4

18:50-07:35

1 stop29h 45m

Brussels Bruxelles-National

Sat 25/4

10:25-16:50

1 stop13h 25m

£634

Panama CityLondon

PTY - LGW

PTYLGW

Panama City Tocumen Intl

Sun 17/5

20:25-16:25

1 stop14h 00m

London Gatwick

Sun 31/5

10:00-18:40

1 stop14h 40m

£682

Panama CityLondon

PTY - LGW

PTYLGW

Panama City Tocumen Intl

Thu 7/5

20:25-09:00

1 stop30h 35m

London Gatwick

Mon 11/5

10:00-18:40

1 stop14h 40m

£688

Flights are sorted by cheapest return flights first.

Deals found on 2/12

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a return flight from Panama City to Heathrow. Price data was last updated on 28 November 2025.

Booking 3 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City?

Currently, December is the cheapest month in which you can book a flight from Panama City (average of £485). Flying from Panama City in August will prove the most costly (average of £777). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

Many airlines operate round-trip flights from Panama City: Air France, United Airlines. These airlines fly to the following popular destinations: London.

Copa Airlines
Copa Airlines
From £125
Air Panama
Air Panama
From £115
Avianca
Avianca
From £123
Wingo
Wingo
From £75

What are popular destinations to fly to from Panama City?

If you’re flying from Panama City, these routes are more frequently taken by airlines Sao Paulo (234 flights per day), San José (139 flights per day) and Guatemala City (96 flights per day).

Bocas Del Toro
Bocas Del Toro
From £103
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £52
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £118
Frankfurt am Main
Frankfurt am Main
From £255

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is Medellín Jose Maria Cordova Intl, with prices starting at £52. Explore other affordable destinations below.

Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From £52
San José Juan Santamaria Intl
San José Juan Santamaria Intl
From £88
Bocas Del Toro
Bocas Del Toro
From £103
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From £118

Airline reviews for flights from Panama City

Get insights into the airlines that provide service from Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing airline for your flight from Panama City. In the last 7 days, Cheapflights users made a total of 858,174 searches.
Read through reviews of airlines serving Panama City, such as Air France and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,500 reviews
Check prices

Crew

8.2

Entertainment

7.0

Food

7.0

Boarding

7.4

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.
Air France
7.4
Good
1,500 reviews
Air France
7.4
Good
1,500 reviews
Check prices

Crew

8.2

Entertainment

7.0

Food

7.0

Boarding

7.4

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.
United Airlines
7.4
Good
9,064 reviews
Air France
7.4
Good
1,500 reviews
Check prices

Crew

8.2

Entertainment

7.0

Food

7.0

Boarding

7.4

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 4 December 2025.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cali, Cartagena. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as £88 to San José (prices may vary depending on the airline and departure time). On average, users have booked flights for £559 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Wingo, Air Panama, and Avianca have the cheapest prices from Panama City. Wingo flights from Panama City to Bogotá El Dorado (£75), Air Panama flights from Panama City to Bocas Del Toro (£115), and Avianca flights from Panama City to Armenia El Eden (£123).

  • What is the cheapest premium economy flight from Panama City?

    Here are some of the cheapest offers we have found for the cheapest premium economy flights from Panama City.
    Panama City Tocumen Intl to Madrid from £1,108
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from £1,220
    Panama City Tocumen Intl to Amsterdam from £2,063

  • What is the cheapest month to fly from Panama City?

    At the present moment the cheapest month to fly from Panama City is currently December; with August being the most expensive. Prices will vary depending on multiple factors such as booking in advance, airline and departure airports and times.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Travel from Panama City to San Pedro Sula from £214 round trip
    Travel from Panama City to London from £545 round trip

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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How does Cheapflights help users find flights from Panama City?

Cheapflights makes it easy to find flights from Panama City by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

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