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Cheap flights from Southampton to Brussels from £101

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/5. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — BRU
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Brussels

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Brussels
Explore the most affordable flight options available from Southampton to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 January 2026.

Fri 6/319:50
SOU
-
BRU
1 stop24h 20m
Multiple Airlines
Fri 13/315:50
BRU
-
SOU
1 stop15h 55m
Multiple Airlines
Deal found 20/1£145
Sat 28/215:25
SOU
-
CRL
2 stops18h 40m
Multiple Airlines
Mon 2/313:10
CRL
-
SOU
2 stops20h 40m
Multiple Airlines
Deal found 20/1£166
Sat 28/213:55
SOU
-
BRU
2 stops18h 10m
Multiple Airlines
Mon 2/309:40
BRU
-
SOU
2 stops24h 10m
Multiple Airlines
Deal found 20/1£167
Wed 18/309:25
SOU
-
BRU
2 stops22h 25m
Multiple Airlines
Fri 20/308:45
BRU
-
SOU
1 stop11h 35m
Multiple Airlines
Deal found 20/1£175
Wed 18/312:00
SOU
-
CRL
2 stops19h 00m
Multiple Airlines
Fri 20/306:25
CRL
-
SOU
1 stop13h 55m
Multiple Airlines
Deal found 20/1£203
Fri 10/417:20
SOU
-
BRU
1 stop13h 15m
KLM
Sun 12/406:20
BRU
-
SOU
1 stop3h 25m
KLM
Deal found 20/1£205
Fri 20/219:50
SOU
-
CRL
1 stop14h 40m
Multiple Airlines
Sun 22/216:30
CRL
-
SOU
2 stops28h 10m
Multiple Airlines
Deal found 20/1£219
Fri 10/418:20
SOU
-
CRL
1 stop3h 30m
Multiple Airlines
Sun 12/418:25
CRL
-
SOU
1 stop3h 20m
Multiple Airlines
Deal found 20/1£235
Fri 20/217:35
SOU
-
BRU
1 stop3h 45m
KLM
Sun 22/210:45
BRU
-
SOU
1 stop22h 35m
KLM
Deal found 20/1£237
Mon 9/217:35
SOU
-
BRU
1 stop13h 00m
KLM
Mon 16/206:15
BRU
-
SOU
1 stop3h 35m
KLM
Deal found 20/1£245
Fri 24/706:50
SOU
-
CRL
2 stops8h 40m
Multiple Airlines
Mon 27/718:55
CRL
-
SOU
2 stops26h 20m
Multiple Airlines
Deal found 20/1£281

Find flight deals from Southampton to Brussels

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 January 2026.

Round-trip from

£145

One-way from

£101

Popular in

June

Cheapest in

April

Average price

£196
easyJet
  • easyJet
  • 6/3-13/3
  • 2 total stops
  • 40h 15m total
  • Southampton to Brussels
Search Deals
17/5
  • 17/5
  • 2 total stops
  • 19h 40m total
  • Southampton to Brussels
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (£22 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£7 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
Use the filters below to find and compare flights from Southampton to Brussels that are best for you.

Fly from

Southampton

Fly to

Brussels

Route

Depart

Return

Price

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

Sat 28/2

13:55-09:05

2 stops18h 10m

Brussels Bruxelles-National

Mon 2/3

09:40-19:40

1 stop11h 00m

£170

SouthamptonBrussels

SOU - CRL

SOUCRL

Southampton Eastleigh

Sat 28/2

15:25-11:05

2 stops18h 40m

Charleroi Brussels

Mon 2/3

13:10-19:40

1 stop7h 30m

£171

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

Wed 18/3

09:25-08:50

2 stops22h 25m

Brussels Bruxelles-National

Fri 20/3

08:45-19:20

1 stop11h 35m

£175

SouthamptonBrussels

SOU - CRL

SOUCRL

Southampton Eastleigh

Wed 18/3

12:00-08:00

2 stops19h 00m

Charleroi Brussels

Fri 20/3

06:25-19:20

1 stop13h 55m

£203

SouthamptonBrussels

SOU - CRL

SOUCRL

Southampton Eastleigh

Fri 20/2

19:50-11:30

1 stop14h 40m

Charleroi Brussels

Sun 22/2

16:30-19:40

2 stops28h 10m

£219

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

Fri 6/3

19:50-08:55

1 stop12h 05m

Brussels Bruxelles-National

Fri 13/3

21:35-14:50

2 stops18h 15m

£234

SouthamptonBrussels

SOU - CRL

SOUCRL

Southampton Eastleigh

Fri 10/4

18:20-22:50

1 stop3h 30m

Charleroi Brussels

Sun 12/4

18:25-20:45

1 stop3h 20m

£235

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

Fri 20/2

17:35-22:20

1 stop3h 45m

Brussels Bruxelles-National

Sun 22/2

10:45-08:20

1 stop22h 35m

£237

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

Mon 9/2

17:35-07:35

1 stop13h 00m

Brussels Bruxelles-National

Mon 16/2

06:15-08:50

1 stop3h 35m

£245

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

Fri 20/2

19:50-08:55

1 stop12h 05m

Brussels Bruxelles-National

Sun 22/2

20:50-08:45

1 stop12h 55m

£247

Flights are sorted by cheapest return flights first.

Deals found on 22/1

Showing 1-10 of 16 results
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2

Best time to book a flight from Southampton to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Brussels

What is the cheapest month to book a flight from Southampton to Brussels?

Currently, October is the cheapest month in which you can book a flight from Southampton to Brussels (average of £59). Flying from Southampton to Brussels in June is currently the most expensive (average of £94). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated 22 January 2026.
Get a feel of what it's like to fly with KLM from Southampton to Brussels by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Crew

8.4

Overall

7.7

Comfort

7.6

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7.7
Good
1,442 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Crew

8.4

Overall

7.7

Comfort

7.6

Food

7.3

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Brussels?

    Southampton Eastleigh (SOU), located 3.5 mi from the city center, is the airport you fly out of when you book flights from Southampton to Brussels. 1 airline have flights from Eastleigh to Brussels on a regular basis. Booking flights from Southampton Eastleigh to Brussels should not be difficult; the airport handles an average of 0 outbound flights to Brussels per day.

  • How long is the flight from Southampton to Brussels?

    Airlines like KLM fly from Southampton to Brussels in about 3h 45m. The time it takes to get you to your destination can typically vary by up to . There are 254 mi between Southampton and Brussels.

  • What is the cheapest airline to fly from Southampton to Brussels round-trip?

    Flying on KLM is currently your cheapest option to Brussels, with prices starting at £160. KLM is currently priced 30% below the average price you’ll pay for this route.

  • Can I find deals for flights from Southampton to Brussels that include hotel bookings?

    Yes. In addition to deals on Southampton to Brussels flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Brussels.

  • Can I find deals for business class flights from Southampton to Brussels?

    Yes. Cheapflights offers flight deals from Southampton to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Brussels?

    Currently, October is the cheapest month in which you can book a flight from Southampton to Brussels (average of £59). Flying from Southampton to Brussels in June is currently the most expensive (average of £94). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Southampton to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Southampton to Charleroi Brussels flights
Manchester to Ostend flights
Heathrow to Antwerp flights
Edinburgh to Antwerp flights
Leeds to Charleroi Brussels flights
Exeter to Bruxelles-National flights
London City to Charleroi Brussels flights
East Midlands to Charleroi Brussels flights
Southend to Antwerp flights
Doncaster to Bruxelles-National flights
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Leeds to Antwerp flights
Grimsby to Bruxelles-National flights
Newquay to Bruxelles-National flights

Top airline flying from Southampton to Brussels

Discover the top airline that operate flights from Southampton to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest£160Average£256FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to Brussels?

When you search for this flight from Southampton to Brussels, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Brussels?

Cheapflights helps you find that perfect flight to Brussels from Southampton by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Southampton to Brussels with no change fees?

Yes, we can. To see specific flights from Southampton to Brussels with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Southampton to Brussels become cheaper?

Of course! You can now track prices for flights from Southampton to Brussels and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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