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Cheap flights from Southampton to Brussels Bruxelles-National Airport from £76

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — BRU
24 may. — 31 may.1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Bruxelles-National

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Bruxelles-National
Explore the most affordable flight options available from Southampton to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 abril 2026.

lun. 1/619:20
SOU
-
BRU
1 stop13h 25m
Multiple Airlines
jue. 4/621:35
BRU
-
SOU
1 stop12h 10m
Multiple Airlines
Deal found 20/4£112
mié. 3/615:35
SOU
-
BRU
2 stops17h 10m
Multiple Airlines
mié. 10/610:35
BRU
-
SOU
2 stops23h 00m
Multiple Airlines
Deal found 19/4£166
mié. 20/509:05
SOU
-
BRU
1 stop4h 35m
KLM
mié. 27/506:20
BRU
-
SOU
1 stop3h 15m
KLM
Deal found 20/4£197
mié. 20/515:35
SOU
-
BRU
2 stops17h 10m
Multiple Airlines
mié. 27/510:30
BRU
-
SOU
1 stop10h 00m
Multiple Airlines
Deal found 20/4£205
lun. 4/519:20
SOU
-
BRU
1 stop12h 20m
Multiple Airlines
mar. 5/517:55
BRU
-
SOU
2 stops15h 10m
Multiple Airlines
Deal found 23/4£208
vie. 5/609:25
SOU
-
BRU
1 stop6h 15m
Multiple Airlines
vie. 12/610:20
BRU
-
SOU
2 stops22h 00m
Multiple Airlines
Deal found 23/4£215
sáb. 6/607:50
SOU
-
BRU
2 stops24h 00m
Multiple Airlines
sáb. 13/609:50
BRU
-
SOU
1 stop10h 40m
Multiple Airlines
Deal found 22/4£221

Find flight deals from Southampton to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 abril 2026.

Round-trip from

£112

One-way from

£76

Popular in

July

Cheapest in

November

Average price

£139
1/6-4/6
  • 1/6-4/6
  • 2 total stops
  • 25h 35m total
  • Southampton to Brussels
Search Deals
11/5
  • 11/5
  • 1 total stop
  • 11h 45m total
  • Southampton to Brussels
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (£6 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£2 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 abril 2026.
Use the filters below to find and compare flights from Southampton to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

mié. 3/6

15:35-09:45

2 stops17h 10m

Brussels Bruxelles-National

mié. 10/6

10:35-08:35

2 stops23h 00m

£166
Fastest return journey

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

mié. 20/5

09:05-14:40

1 stop4h 35m

Brussels Bruxelles-National

mié. 27/5

06:20-08:35

1 stop3h 15m

£197

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

vie. 5/6

09:25-16:40

1 stop6h 15m

Brussels Bruxelles-National

vie. 12/6

10:20-19:30

1 stop10h 10m

£208

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

mar. 5/5

13:25-09:55

2 stops19h 30m

Brussels Bruxelles-National

vie. 8/5

10:20-19:30

1 stop10h 10m

£240

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

mar. 16/6

06:45-09:55

2 stops26h 10m

Brussels Bruxelles-National

mié. 17/6

16:00-09:25

2 stops18h 25m

£395

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

lun. 1/6

06:45-19:10

2 stops35h 25m

Brussels Bruxelles-National

vie. 5/6

17:00-12:00

2 stops20h 00m

£450

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

vie. 22/5

20:00-09:40

1 stop12h 40m

Brussels Bruxelles-National

vie. 29/5

21:25-08:40

1 stop12h 15m

£452

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

vie. 4/9

08:55-20:40

2 stops10h 45m

Brussels Bruxelles-National

dom. 6/9

20:40-08:25

2 stops12h 45m

£492

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

mié. 21/10

08:55-20:25

2 stops10h 30m

Brussels Bruxelles-National

mié. 4/11

11:50-19:25

2 stops8h 35m

£497

SouthamptonBrussels

SOU - BRU

SOUBRU

Southampton Eastleigh

vie. 22/5

20:00-09:40

1 stop12h 40m

Brussels Bruxelles-National

vie. 29/5

21:30-14:25

2 stops17h 55m

£533

Flights are sorted by cheapest return flights first.

Deals found on 22/4

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Southampton to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated 24 abril 2026.
Check out reviews from past customers who have flown with KLM from Southampton to Brussels Bruxelles-National Airport to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,508 reviews
Check prices

Comfort

7.7

Crew

8.4

Overall

7.8

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,508 reviews
KLM
7.8
Good
1,508 reviews
Check prices

Comfort

7.7

Crew

8.4

Overall

7.8

Boarding

7.8

Entertainment

7.1

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Southampton to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Brussels Bruxelles-National?

    Most people fly from Southampton Eastleigh (SOU) if they book a flight from Southampton to Brussels Bruxelles-National. On average, Eastleigh has 0 outbound flights to Brussels Bruxelles-National per day from 1 airline. Southampton Eastleigh is conveniently located just 3.5 mi from Southampton’s city center.

  • How long is the flight from Southampton to Brussels Bruxelles-National Airport?

    KLM can get you from Southampton to Brussels Bruxelles-National Airport in just under 4h 35m. Your travel time can differ by up to . The distance between Southampton and Brussels Bruxelles-National Airport is about 254 mi.

  • What is the cheapest airline to fly from Southampton to Brussels Bruxelles-National Airport round-trip?

    Flying on KLM is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at £177.

  • Can I find deals for flights from Southampton to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Southampton to Bruxelles-National flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Bruxelles-National.

  • Can I find deals for business class flights from Southampton to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Southampton to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Leuven
Mechelen
Ypres
Mons
Charleroi
Hasselt
Dinant
Zaventem

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Southampton to Bruxelles-National

Discover the top airline that operate flights from Southampton to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 abril 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest£177Average£253FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to Bruxelles-National?

Cheapflights makes it easy to find Southampton to Bruxelles-National flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

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Millions of users choose and trust Cheapflights to book the best flight deals from Southampton to Bruxelles-National for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Southampton to Bruxelles-National with no change fees?

Need flexible booking options for your flight to Bruxelles-National from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to Bruxelles-National become cheaper?

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