Find flights
When to book
Airlines
FAQs

Cheap flights from Manchester to Greenville from £287

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — GSP
18 Apr — 25 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Greenville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Greenville
Explore the most affordable flight options available from Manchester to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 19 March 2026.

Tue 14/409:30
MAN
-
GSP
2 stops30h 06m
British Airways
Tue 21/411:01
GSP
-
MAN
2 stops21h 04m
British Airways
Deal found 17/3£725
Tue 14/413:00
MAN
-
GSP
1 stop14h 13m
Virgin Atlantic
Tue 21/417:50
GSP
-
MAN
1 stop32h 25m
Virgin Atlantic
Deal found 17/3£751
Wed 29/410:35
MAN
-
GSP
2 stops17h 10m
United Airlines
Wed 6/510:33
GSP
-
MAN
2 stops18h 17m
United Airlines
Deal found 15/3£753
Thu 16/407:00
MAN
-
GSP
2 stops18h 47m
Lufthansa
Thu 23/419:42
GSP
-
MAN
2 stops22h 33m
Lufthansa
Deal found 17/3£757
Wed 29/410:40
MAN
-
GSP
1 stop28h 40m
Delta
Wed 6/511:06
GSP
-
MAN
2 stops16h 09m
Delta
Deal found 15/3£764
Thu 30/410:35
MAN
-
GSP
2 stops28h 23m
United Airlines
Thu 7/514:52
GSP
-
MAN
2 stops14h 33m
United Airlines
Deal found 16/3£784
Thu 16/413:00
MAN
-
GSP
1 stop12h 02m
Delta
Thu 23/419:59
GSP
-
MAN
2 stops15h 46m
Delta
Deal found 17/3£797
Sun 31/516:35
MAN
-
GSP
2 stops47h 15m
British Airways
Tue 4/810:37
GSP
-
MAN
2 stops21h 28m
British Airways
Deal found 15/3£856
Sun 31/511:10
MAN
-
GSP
2 stops51h 45m
Lufthansa
Tue 4/819:49
GSP
-
MAN
2 stops33h 01m
Lufthansa
Deal found 16/3£857
Sun 31/516:35
MAN
-
GSP
2 stops47h 15m
British Airways
Mon 3/807:52
GSP
-
MAN
2 stops22h 38m
British Airways
Deal found 14/3£860

Find flight deals from Manchester to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 19 March 2026.

Round-trip from

£725

One-way from

£287

Popular in

March

Cheapest in

November

Average price

£1,159
British Airways
  • British Airways
  • 14/4-21/4
  • 4 total stops
  • 51h 10m total
  • Manchester to Greenville
Search Deals
28/4
  • 28/4
  • 3 total stops
  • 45h 13m total
  • Manchester to Greenville
Search Deals
Highest demand for flights based on searches. 17% potential increase in price (£136 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£24 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 19 March 2026.
Use the filters below to find and compare flights from Manchester to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Wed 29/4

10:40-10:20

1 stop28h 40m

Greenville

Wed 6/5

11:06-08:15

2 stops16h 09m

£764
Fastest return journey

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Thu 16/4

13:00-20:02

1 stop12h 02m

Greenville

Thu 23/4

19:59-16:45

2 stops15h 46m

£797

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 31/5

11:10-09:55

2 stops51h 45m

Greenville

Mon 3/8

10:30-09:50

2 stops18h 20m

£857

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 31/5

11:10-09:55

2 stops51h 45m

Greenville

Tue 4/8

19:49-09:50

2 stops33h 01m

£857

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 31/5

16:35-10:50

2 stops47h 15m

Greenville

Mon 3/8

07:52-11:30

2 stops22h 38m

£860

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 31/5

11:15-22:33

1 stop16h 18m

Greenville

Tue 4/8

18:20-14:00

2 stops14h 40m

£918

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 31/5

11:15-22:33

1 stop16h 18m

Greenville

Mon 3/8

18:20-14:00

2 stops14h 40m

£918

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 31/5

11:15-09:04

1 stop26h 49m

Greenville

Mon 3/8

15:42-08:50

1 stop12h 08m

£921
Cheapest one-way

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Thu 30/4

06:00-16:53

3 stops39h 53m

£358

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sun 26/4

19:45-12:21

3 stops45h 36m

£405

Flights are sorted by cheapest return flights first.

Deals found on 14/3

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Greenville

What is the cheapest month to book a flight from Manchester to Greenville?

Currently, September is the cheapest month in which you can book a flight from Manchester to Greenville (average of £554). Flying from Manchester to Greenville in December is currently the most expensive (average of £740). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated 19 March 2026.
Check out reviews from past customers who have flown with Virgin Atlantic from Manchester to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
682 reviews
Check prices

Food

6.9

Entertainment

7.6

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
682 reviews
Virgin Atlantic
7.5
Good
682 reviews
Check prices

Food

6.9

Entertainment

7.6

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from Manchester to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Greenville?

    Departing from Manchester to Greenville will take you 28h 40m. Airlines will cover a distance of 3936 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Manchester to Greenville round-trip?

    Virgin Atlantic, at £585, was found to be the cheapest airline from Manchester to Greenville.. Virgin Atlantic is priced at 31% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Manchester to Greenville that include hotel bookings?

    Yes. In addition to deals on Manchester to Greenville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Greenville.

  • Can I find deals for business class flights from Manchester to Greenville?

    Yes. Cheapflights offers flight deals from Manchester to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Greenville?

    Currently, September is the cheapest month in which you can book a flight from Manchester to Greenville (average of £554). Flying from Manchester to Greenville in December is currently the most expensive (average of £740). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to Charlotte flights
Gatwick to Charlotte flights
Heathrow to Charleston flights
London City to Charlotte flights
Stansted to Charlotte flights
Gatwick to Charleston flights
Heathrow to Greenville flights
Heathrow to Myrtle Beach flights
Manchester to Charlotte flights
Heathrow to Savannah flights
London City to Charleston flights
Edinburgh to Charlotte flights
Manchester to Charleston flights
Manchester to Savannah flights
Gatwick to Savannah flights
Heathrow to Columbia flights
Gatwick to Myrtle Beach flights
Heathrow to Augusta flights
Leeds to Charlotte flights
London City to Myrtle Beach flights
Manchester to Columbia flights
Bristol to Charlotte flights
London City to Columbia flights
London City to Greenville flights
Birmingham to Charlotte flights
Birmingham to Savannah flights
Heathrow to Hilton Head Island flights
Birmingham to Myrtle Beach flights
London City to Savannah flights
Birmingham to Columbia flights
Birmingham to Charleston flights
Manchester to Myrtle Beach flights
Heathrow to Florence flights
Stansted to Myrtle Beach flights
Newcastle upon Tyne to Greenville flights
Newcastle upon Tyne to Charlotte flights
Manchester to Hilton Head Island flights
Edinburgh to Myrtle Beach flights
Leeds to Savannah flights
Edinburgh to Florence flights
Darlington to Greenville flights
Leeds to Greenville flights
Bristol to Greenville flights
Birmingham to Greenville flights
Darlington to Charlotte flights
Leeds to Charleston flights
Bristol to Columbia flights

Top airline flying from Manchester to Greenville

Discover the top airline that operate flights from Manchester to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 19 March 2026.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£585Average£757FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Greenville?

Deals for Manchester to Greenville flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Greenville?

Cheapflights simply makes it quick and affordable to book flights from Manchester to Greenville by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Manchester to Greenville with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Manchester to Greenville, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Manchester to Greenville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Greenville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.