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Cheap flights from Manchester to South Carolina from £241

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
9 Apr — 16 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 March 2026.

Tue 21/413:05
MAN
-
MYR
2 stops25h 38m
Multiple Airlines
Tue 28/414:23
MYR
-
MAN
2 stops16h 17m
Multiple Airlines
Deal found 7/3£498
Thu 23/421:10
MAN
-
MYR
2 stops26h 54m
Multiple Airlines
Thu 30/414:23
MYR
-
MAN
2 stops24h 02m
Multiple Airlines
Deal found 9/3£579
Sat 2/518:20
MAN
-
MYR
3 stops29h 44m
Multiple Airlines
Sat 9/509:18
MYR
-
MAN
3 stops29h 57m
Multiple Airlines
Deal found 8/3£595
Mon 20/409:35
MAN
-
CLT
2 stops18h 14m
Scandinavian Airlines
Tue 5/509:46
CLT
-
MAN
2 stops18h 09m
Scandinavian Airlines
Deal found 9/3£605
Sun 5/419:30
MAN
-
CLT
2 stops32h 03m
Scandinavian Airlines
Sun 19/406:00
CLT
-
MAN
2 stops32h 45m
Scandinavian Airlines
Deal found 5/3£608
Sun 19/419:30
MAN
-
CLT
2 stops33h 29m
Multiple Airlines
Sat 25/421:54
CLT
-
MAN
3 stops30h 46m
Multiple Airlines
Deal found 5/3£614
Thu 14/521:10
MAN
-
CLT
2 stops30h 37m
Scandinavian Airlines
Thu 4/606:10
CLT
-
MAN
2 stops31h 20m
Scandinavian Airlines
Deal found 5/3£617
Wed 7/1009:35
MAN
-
CLT
2 stops17h 41m
Scandinavian Airlines
Wed 14/1010:00
CLT
-
MAN
2 stops27h 30m
Scandinavian Airlines
Deal found 8/3£630
Mon 28/909:35
MAN
-
CLT
2 stops17h 48m
Scandinavian Airlines
Mon 5/1014:20
CLT
-
MAN
2 stops23h 10m
Scandinavian Airlines
Deal found 9/3£632
Thu 16/421:10
MAN
-
CLT
2 stops30h 39m
Scandinavian Airlines
Mon 20/406:00
CLT
-
MAN
2 stops25h 05m
Scandinavian Airlines
Deal found 8/3£638
Mon 20/409:35
MAN
-
CLT
2 stops18h 14m
Scandinavian Airlines
Mon 27/406:00
CLT
-
MAN
2 stops25h 05m
Scandinavian Airlines
Deal found 6/3£647
Sat 25/408:10
MAN
-
GSP
2 stops19h 35m
Multiple Airlines
Sat 30/511:18
GSP
-
MAN
2 stops28h 07m
Multiple Airlines
Deal found 10/3£666

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 10 March 2026.

Round-trip from

£498

One-way from

£241

Popular in

August

Cheapest in

January

Average price

£694
21/4-28/4
  • 21/4-28/4
  • 4 total stops
  • 41h 55m total
  • Manchester to South Carolina
Search Deals
16/4
  • 16/4
  • 2 total stops
  • 47h 33m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£58 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 March 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Thu 23/4

21:10-19:04

2 stops26h 54m

Myrtle Beach Intl

Thu 30/4

14:23-19:25

2 stops24h 02m

£579

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Sat 2/5

13:05-08:13

2 stops24h 08m

Myrtle Beach Intl

Sat 9/5

09:18-11:40

2 stops21h 22m

£656

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 10/5

19:30-22:47

2 stops32h 17m

Charlotte Douglas

Wed 3/6

06:00-08:55

2 stops45h 55m

£683

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 10/5

19:30-22:47

2 stops32h 17m

Charlotte Douglas

Thu 28/5

06:10-08:55

2 stops21h 45m

£683

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 10/5

19:30-22:47

2 stops32h 17m

Charlotte Douglas

Fri 29/5

06:10-08:55

2 stops21h 45m

£683

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Thu 16/4

06:55-00:24

2 stops22h 29m

Charleston

Thu 23/4

11:14-11:30

2 stops19h 16m

£714

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Mon 20/4

13:00-22:42

1 stop14h 42m

Savannah/Hilton Head

Mon 27/4

11:21-08:15

2 stops15h 54m

£719

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Tue 21/4

09:30-18:00

2 stops37h 30m

Myrtle Beach Intl

Sat 25/4

18:30-22:35

2 stops47h 05m

£721

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 23/4

06:55-23:59

2 stops22h 04m

Savannah/Hilton Head

Thu 7/5

10:52-09:45

2 stops17h 53m

£738

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Tue 21/4

10:35-09:51

2 stops28h 16m

Columbia Metropolitan

Tue 28/4

14:38-09:50

2 stops14h 12m

£739

Flights are sorted by cheapest return flights first.

Deals found on 9/3

Showing 1-10 of 49 resultsSorted by cheapest first
1
2
3
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5

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £536). Flying from Manchester to South Carolina in July is currently the most expensive (average of £674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 10 March 2026.
See what other customers who have flown with Delta,KLM, andVirgin Atlantic from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews
Check prices

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews
Check prices

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.8
Good
1,468 reviews
Delta
7.9
Good
8,276 reviews
Check prices

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
680 reviews
Delta
7.9
Good
8,276 reviews
Check prices

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,415 reviews
Delta
7.9
Good
8,276 reviews
Check prices

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,781 reviews
Delta
7.9
Good
8,276 reviews
Check prices

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Scandinavian Airlines, British Airways, and Virgin Atlantic can get you from Manchester to South Carolina in just under 14h 42m. Your travel time can differ by up to 17h 35m. Manchester and South Carolina are separated by a distance of 4033 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Savannah/Hilton Head or Manchester - Greenville, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £536). Flying from Manchester to South Carolina in July is currently the most expensive (average of £674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Manchester to South Carolina

Discover the top 7 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 March 2026.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£536Average£647FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£540Average£682FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£569Average£756FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£588Average£773FlexibilityNo cancel feeOn-time75%
Search KLM flights
American AirlinesCheapest£625Average£679FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest£637Average£767FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£787Average£1,011FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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