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Cheap flights from Manchester to South Carolina from £336

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
7 Jul — 14 Jul1
1 adult

Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 2 July 2025.

Round-trip from

£602

One-way from

£336

Popular in

August

Cheapest in

February

Average price

£854
United Airlines
  • United Airlines
  • 3/9-20/9
  • 4 total stops
  • 50h 02m total
  • Manchester to South Carolina
Search Deals
15/9
  • 15/9
  • 3 total stops
  • 28h 30m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£64 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£18 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 July 2025.

Wed 3/909:10MAN - SAV
2 stops30h 41mUnited Airlines
Sat 20/910:09SAV - MAN
2 stops19h 21mUnited Airlines
Deal found 30/6£602
Wed 3/913:05MAN - SAV
3 stops38h 44mMultiple Airlines
Sat 20/912:59SAV - MAN
2 stops17h 41mMultiple Airlines
Deal found 30/6£603
Wed 3/914:15MAN - SAV
1 stop25h 20mDelta
Sat 20/911:40SAV - MAN
2 stops17h 15mDelta
Deal found 30/6£634
Wed 9/714:40MAN - CHS
1 stop32h 24mAer Lingus
Wed 23/718:59CHS - MAN
1 stop30h 51mAer Lingus
Deal found 30/6£659
Fri 26/906:05MAN - MYR
2 stops37h 26mUnited Airlines
Mon 29/916:43MYR - MAN
2 stops36h 57mUnited Airlines
Deal found 30/6£660
Mon 10/1116:00MAN - CLT
3 stops36h 30mMultiple Airlines
Mon 24/1109:30CLT - MAN
3 stops25h 45mMultiple Airlines
Deal found 30/6£674
Wed 22/1012:40MAN - SAV
2 stops26h 51mIcelandair
Tue 28/1012:20SAV - MAN
2 stops18h 25mIcelandair
Deal found 30/6£704
Fri 15/807:40MAN - MYR
3 stops28h 50mMultiple Airlines
Fri 22/812:59MYR - MAN
3 stops25h 51mMultiple Airlines
Deal found 1/7£709
Fri 24/1013:05MAN - CLT
2 stops38h 02mScandinavian Airlines
Sat 1/1114:20CLT - MAN
2 stops39h 10mScandinavian Airlines
Deal found 30/6£738
Wed 22/1014:15MAN - SAV
1 stop12h 11mVirgin Atlantic
Tue 28/1007:25SAV - MAN
1 stop19h 45mVirgin Atlantic
Deal found 30/6£745
Wed 22/1011:00MAN - SAV
2 stops28h 31mTAP AIR PORTUGAL
Tue 28/1012:20SAV - MAN
2 stops18h 15mTAP AIR PORTUGAL
Deal found 1/7£746
Wed 9/711:00MAN - CHS
2 stops28h 15mTAP AIR PORTUGAL
Wed 23/711:00CHS - MAN
2 stops25h 05mTAP AIR PORTUGAL
Deal found 2/7£749

Cheapflights Fare Finder

Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 July 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 3/9

09:10-10:51

2 stops30h 41m

Savannah/Hilton Head

Sat 20/9

10:09-10:30

2 stops19h 21m

£602

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 3/9

13:05-22:49

3 stops38h 44m

Savannah/Hilton Head

Sat 20/9

12:59-11:40

2 stops17h 41m

£603

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 3/9

14:15-10:35

1 stop25h 20m

Savannah/Hilton Head

Sat 20/9

11:40-09:55

2 stops17h 15m

£634

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 26/9

06:05-14:31

2 stops37h 26m

Myrtle Beach Intl

Mon 29/9

16:43-10:40

2 stops36h 57m

£660

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Mon 10/11

16:00-23:30

3 stops36h 30m

Charlotte Douglas

Mon 24/11

09:30-16:15

3 stops25h 45m

£674

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 22/10

12:40-10:31

2 stops26h 51m

Savannah/Hilton Head

Tue 28/10

12:20-10:45

2 stops18h 25m

£704

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 15/8

07:40-07:30

3 stops28h 50m

Myrtle Beach Intl

Fri 22/8

12:59-19:50

3 stops25h 51m

£709

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 24/10

13:05-22:07

2 stops38h 02m

Charlotte Douglas

Sat 1/11

14:20-09:30

2 stops39h 10m

£738

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 22/10

14:15-21:26

1 stop12h 11m

Savannah/Hilton Head

Tue 28/10

07:25-07:10

1 stop19h 45m

£745

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 22/10

11:00-10:31

2 stops28h 31m

Savannah/Hilton Head

Tue 28/10

12:20-10:35

2 stops18h 15m

£746

Flights are sorted by cheapest return flights first.

Deals found on 30/6

Showing 1-10 of 34 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 2 July 2025.

When flying from Manchester to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 2 July 2025.
See what other customers who have flown with Delta, KLM, andSWISS from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very Good
7,974 reviews
Check prices

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very Good
7,974 reviews
Delta
8.0
Very Good
7,974 reviews
Check prices

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,366 reviews
Delta
8.0
Very Good
7,974 reviews
Check prices

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
SWISS
7.5
Good
1,654 reviews
Delta
8.0
Very Good
7,974 reviews
Check prices

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very Good
7,974 reviews
Check prices

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Virgin Atlantic
7.4
Good
654 reviews
Delta
8.0
Very Good
7,974 reviews
Check prices

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • What are the cheapest airlines to fly from Manchester to South Carolina one-way?

    To fly one-way, consider booking your trip with Aer Lingus, which is currently one of the cheapest options available, starting at £721. Ethiopian Air flights start at £1,716 while deals on United Airlines start at £2,474 one-way.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Columbia Metropolitan or Manchester - Savannah/Hilton Head, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Manchester to South Carolina

Discover the top 8 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 July 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£513Average£629FlexibilityNo cancel feeOn-time76%
Search Finnair flights
Air FranceCheapest£539Average£760FlexibilityNo cancel feeOn-time77%
Search Air France flights
British AirwaysCheapest£545Average£686FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapest£556Average£811FlexibilityNo cancel feeOn-time75%
Search KLM flights
Virgin AtlanticCheapest£573Average£712FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
American AirlinesCheapest£580Average£714FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest£608Average£707FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£765Average£922FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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