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Cheap flights from Santiago to Guatemala City from £227

SCL — GUA
19 Nov — 26 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Guatemala City

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Guatemala City

Tue 17/1116:15 -
1 stop11h 40m
Sun 22/1112:25 -
2 stops14h 20m
Deal found 15/10£396
Thu 3/1205:07 -
1 stop21h 46m
Tue 29/1206:24 -
2 stops18h 19m
Deal found 16/10£406
Wed 11/1101:02 -
1 stop11h 37m
Thu 12/1113:08 -
1 stop10h 40m
Deal found 19/10£417
Tue 22/1201:27 -
1 stop10h 19m
Wed 13/107:19 -
1 stop13h 21m
Deal found 16/10£429
Mon 9/1103:48 -
1 stop11h 02m
Wed 18/1104:16 -
1 stop17h 08m
Deal found 16/10£441
Fri 16/1001:44 -
1 stop13h 03m
Sat 7/1106:19 -
2 stops15h 05m
Deal found 16/10£453
Mon 14/1216:15 -
1 stop23h 50m
Tue 29/1209:20 -
1 stop17h 25m
Deal found 16/10£461
Sun 8/1105:07 -
1 stop20h 35m
Fri 20/1103:53 -
1 stop16h 43m
Deal found 16/10£488

Find flight deals from Santiago to Guatemala City

Round-trip from

£396

One-way from

£227

Popular in

July

Cheapest in

April

Average price

£416
Avianca
  • Avianca
  • 17/11-22/11
  • 3 total stops
  • 26h 00m total
  • Santiago to Guatemala City
Search Deals
Avianca
  • Avianca
  • 3/11-31/12
  • 1 total stop
  • 13h 55m total
  • Santiago to Guatemala City
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (£8 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (£4 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.

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Route

Depart

Return

Price

Cheapest return flight

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Tue 10/11

02:10-13:05

1 stop13h 55m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£227

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Wed 4/11

07:30-17:25

1 stop12h 55m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£227

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Wed 28/10

02:10-11:30

2 stops12h 20m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£233

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Fri 6/11

02:10-11:30

2 stops12h 20m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£233

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Wed 9/12

12:20-08:46

1 stop23h 26m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£236

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Fri 9/4

02:10-21:11

2 stops21h 01m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£236

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Mon 15/3

01:16-21:11

2 stops22h 55m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£236

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Fri 22/1

05:13-23:06

1 stop20h 53m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£247
Fastest return journey

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Tue 22/12

01:27-08:46

1 stop10h 19m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£247

SantiagoGuatemala City

SCL Santiago Arturo Merino Benitez - GUA Guatemala City La Aurora

SCLGUA

Santiago Arturo Merino Benitez

Thu 17/12

12:20-21:36

2 stops12h 16m

Guatemala City La Aurora

Wed 31/12

00:00-03:00

Nonstop0h 00m

£284

Flights are sorted by cheapest return flights first.

Deals found on 19/10

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guatemala City

How far ahead should I book a flight from Santiago to Guatemala City?

Booking 4 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Guatemala City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Guatemala City?

Currently, April is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of £393). Flying from Santiago to Guatemala City in July is currently the most expensive (average of £453). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santiago to Guatemala City?

Airfare is typical for this route at the moment.

Santiago to Guatemala City flights typically cost between £388 and £470 in November.
The cheapest return price found within the last 5 days was £396 on Avianca (17 Nov–22 Nov).

Related info for your journey

  • How long is the flight from Santiago to Guatemala City?

    There are many flights that can get you from Santiago to Guatemala City in 24h 13m. Fly via Copa Airlines to get the fastest option. The distance from Santiago to Guatemala City is about 3559 mi.

  • Can I find deals for flights from Santiago to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santiago to Guatemala City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guatemala City.

  • Can I find deals for business class flights from Santiago to Guatemala City?

    Yes. Cheapflights offers flight deals from Santiago to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guatemala City?

    Currently, April is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of £393). Flying from Santiago to Guatemala City in July is currently the most expensive (average of £453). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Guatemala City La Aurora Airport car hire

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Why should you use Cheapflights to find cheap flight tickets from Santiago to Guatemala City?

Cheapflights helps you find that perfect flight to Guatemala City from Santiago by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

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Users can book flights with no change fees policies with our dedicated filters. Book flights from Santiago to Guatemala City flexibly with Cheapflights today.

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