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Cheap flights from Manchester to Knoxville from £376

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TYS
26 fev — 5 mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Knoxville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 janeiro 2026.

seg 7/913:00
MAN
-
TYS
1 stop13h 46m
Virgin Atlantic
ter 22/919:20
TYS
-
MAN
1 stop30h 55m
Virgin Atlantic
Deal found 26/1£619
seg 2/213:00
MAN
-
TYS
2 stops15h 45m
Virgin Atlantic
ter 10/217:00
TYS
-
MAN
2 stops18h 05m
Virgin Atlantic
Deal found 24/1£620
qui 19/213:00
MAN
-
TYS
2 stops26h 49m
United Airlines
seg 23/206:45
TYS
-
MAN
2 stops21h 00m
United Airlines
Deal found 25/1£621
qui 12/313:30
MAN
-
TYS
1 stop14h 27m
Virgin Atlantic
qui 19/318:38
TYS
-
MAN
1 stop11h 52m
Virgin Atlantic
Deal found 26/1£630
seg 7/908:00
MAN
-
TYS
2 stops18h 44m
British Airways
ter 22/913:45
TYS
-
MAN
2 stops15h 00m
British Airways
Deal found 26/1£632
sáb 25/410:35
MAN
-
TYS
2 stops29h 15m
United Airlines
dom 3/509:40
TYS
-
MAN
2 stops26h 40m
United Airlines
Deal found 25/1£657
sáb 25/416:45
MAN
-
TYS
2 stops34h 40m
British Airways
dom 3/518:38
TYS
-
MAN
2 stops21h 52m
British Airways
Deal found 26/1£686
sex 1/505:55
MAN
-
TYS
2 stops33h 54m
United Airlines
sex 8/507:00
TYS
-
MAN
2 stops21h 50m
United Airlines
Deal found 25/1£696
sáb 25/413:15
MAN
-
TYS
1 stop25h 09m
Delta
dom 3/509:05
TYS
-
MAN
1 stop17h 10m
Delta
Deal found 26/1£701

Find flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 27 janeiro 2026.

Round-trip from

£621

One-way from

£376

Popular in

August

Cheapest in

March

Average price

£649
United Airlines
  • United Airlines
  • 19/2-23/2
  • 4 total stops
  • 47h 49m total
  • Manchester to Knoxville
Search Deals
2/2
  • 2/2
  • 3 total stops
  • 59h 57m total
  • Manchester to Knoxville
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (£70 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 27 janeiro 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Manchester

Fly to

Knoxville

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

qui 26/2

06:00-20:37

2 stops19h 37m

Knoxville McGhee Tyson

seg 2/3

06:45-08:45

2 stops21h 00m

£621

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

qui 19/2

13:00-10:49

2 stops26h 49m

Knoxville McGhee Tyson

seg 23/2

06:45-08:45

2 stops21h 00m

£621

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

qui 12/3

09:25-10:49

2 stops29h 24m

Knoxville McGhee Tyson

qui 19/3

10:55-08:45

2 stops17h 50m

£621

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

qui 12/3

13:30-23:57

1 stop14h 27m

Knoxville McGhee Tyson

qui 19/3

18:38-10:30

1 stop11h 52m

£630

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

sáb 25/4

10:35-10:50

2 stops29h 15m

Knoxville McGhee Tyson

dom 3/5

09:40-17:20

2 stops26h 40m

£657

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

sáb 25/4

16:45-22:25

2 stops34h 40m

Knoxville McGhee Tyson

dom 3/5

18:38-21:30

2 stops21h 52m

£686

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

sex 1/5

05:55-10:49

2 stops33h 54m

Knoxville McGhee Tyson

sex 8/5

07:00-09:50

2 stops21h 50m

£696

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

sáb 25/4

15:20-11:17

2 stops24h 57m

Knoxville McGhee Tyson

dom 3/5

05:44-07:15

1 stop20h 31m

£701

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

seg 2/2

09:00-15:57

3 stops59h 57m

£376

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

seg 2/2

09:00-23:45

1 stop19h 45m

£823

Flights are sorted by cheapest return flights first.

Deals found on 26/1

Showing 1-10 of 11 results
1
2

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester to Knoxville?

Use this chart to determine the optimal time to book a return flight from Manchester to Knoxville. Price data was last updated on 23 January 2026.

The best time to book flights from Manchester to Knoxville is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £344). Flying from Manchester to Knoxville in July is currently the most expensive (average of £699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated 27 janeiro 2026.
Read reviews from past customers who have flown with Delta, Finnair, andVirgin Atlantic from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,118 reviews
Check prices

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,118 reviews
Delta
7.9
Good
8,118 reviews
Check prices

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Finnair
7.6
Good
1,356 reviews
Delta
7.9
Good
8,118 reviews
Check prices

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
678 reviews
Delta
7.9
Good
8,118 reviews
Check prices

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,203 reviews
Delta
7.9
Good
8,118 reviews
Check prices

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,702 reviews
Delta
7.9
Good
8,118 reviews
Check prices

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Knoxville?

    Airlines like United Airlines and Virgin Atlantic fly from Manchester to Knoxville in about 14h 27m. The time it takes to get you to your destination can typically vary by up to 5h 10m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Knoxville round-trip?

    Currently priced at £537, United Airlines will fly you from Manchester to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from British Airways and Virgin Atlantic - these airlines can fly you to your destination from £560 and £566, respectively. You may be able to fly from Manchester to Knoxville for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £344). Flying from Manchester to Knoxville in July is currently the most expensive (average of £699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee

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Top 5 airlines flying from Manchester to Knoxville

Discover the top 5 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 27 janeiro 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£537Average£631FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapest£560Average£649FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£566Average£723FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
FinnairCheapest£569Average£644FlexibilityNo cancel feeOn-time76%
Search Finnair flights
DeltaCheapest£695Average£803FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Knoxville?

When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?

Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Knoxville with no change fees?

Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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