Cheap flights from Manchester to Knoxville from £683
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TYS
8 Jan — 15 Jan1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in March or January, booked 80 days in advance, depart on a Friday or Tuesday and return on a Monday
Cheap flight deals from Manchester to Knoxville
Enter your travel dates to find the best prices.
Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 December 2025.
Mon 8/1210:25MAN - TYS
1 stop16h 24mMultiple Airlines
Mon 15/1213:05TYS - MAN
2 stops22h 00mMultiple Airlines
Deal found 7/12£999
Mon 8/1220:40MAN - TYS
2 stops30h 00mAer Lingus
Mon 15/1214:58TYS - MAN
2 stops17h 27mAer Lingus
Deal found 7/12£1,008
Mon 8/1218:30MAN - TYS
4 stops49h 13mEthiopian Air
Mon 15/1214:30TYS - MAN
4 stops36h 50mEthiopian Air
Deal found 7/12£2,815
Best flights from Manchester to Knoxville
Discover carefully curated flight deals from Manchester to Knoxville that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 9 December 2025.
Wed 21/109:50MAN - TYS
2 stops17h 19mBritish Airways
Wed 28/117:15TYS - MAN
2 stops16h 45mBritish Airways
Deal found 7/12£683
Wed 21/113:30MAN - TYS
1 stop24h 51mDelta
Wed 28/113:00TYS - MAN
2 stops16h 10mDelta
Deal found 7/12£702
Mon 4/511:00MAN - TYS
1 stop12h 15mVirgin Atlantic
Mon 11/516:00TYS - MAN
1 stop11h 10mVirgin Atlantic
Deal found 7/12£712
Mon 5/110:25MAN - TYS
2 stops35h 51mKLM
Mon 12/118:09TYS - MAN
2 stops33h 11mKLM
Deal found 8/12£712
Mon 4/507:00MAN - TYS
2 stops17h 41mUnited Airlines
Mon 11/519:20TYS - MAN
2 stops34h 05mUnited Airlines
Deal found 7/12£717
Thu 22/105:40MAN - TYS
2 stops16h 09mBritish Airways
Mon 26/114:19TYS - MAN
2 stops18h 41mBritish Airways
Deal found 8/12£712
Mon 4/514:50MAN - TYS
2 stops23h 21mDelta
Mon 11/510:05TYS - MAN
1 stop17h 05mDelta
Deal found 7/12£725
Sat 25/418:15MAN - TYS
2 stops32h 12mBritish Airways
Sun 3/518:22TYS - MAN
2 stops37h 53mBritish Airways
Deal found 7/12£725
Last-minute flights from Manchester to Knoxville
Discover last-minute flight deals from Manchester to Knoxville. Data last updated 9 December 2025 and is based on user searches.
Mon 8/1210:25MAN - TYS
1 stop16h 24mMultiple Airlines
Mon 15/1213:05TYS - MAN
2 stops22h 00mMultiple Airlines
Deal found 7/12£999
Mon 5/110:25MAN - TYS
2 stops35h 51mKLM
Mon 12/118:09TYS - MAN
2 stops33h 11mKLM
Deal found 8/12£712
Mon 5/110:25MAN - TYS
2 stops18h 20mMultiple Airlines
Mon 12/113:00TYS - MAN
2 stops36h 40mMultiple Airlines
Deal found 8/12£732
Wed 21/109:50MAN - TYS
2 stops17h 19mBritish Airways
Wed 28/117:15TYS - MAN
2 stops16h 45mBritish Airways
Deal found 7/12£683
Wed 21/113:30MAN - TYS
1 stop24h 51mDelta
Wed 28/113:00TYS - MAN
2 stops16h 10mDelta
Deal found 7/12£702
Wed 21/106:00MAN - TYS
3 stops18h 27mUnited Airlines
Wed 28/114:25TYS - MAN
2 stops16h 55mUnited Airlines
Deal found 7/12£791
Thu 22/107:45MAN - TYS
2 stops19h 24mBritish Airways
Mon 26/114:19TYS - MAN
2 stops16h 26mBritish Airways
Deal found 6/12£713
Find flight deals from Manchester to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 9 December 2025.
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 December 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.
Fly from
Manchester
Fly to
Knoxville
Route
Depart
Return
Price
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Wed 21/1
09:50-22:09
2 stops17h 19m
Knoxville McGhee Tyson
Wed 28/1
17:15-15:00
2 stops16h 45m
£683
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Wed 21/1
13:30-09:21
1 stop24h 51m
Knoxville McGhee Tyson
Wed 28/1
13:00-10:10
2 stops16h 10m
£702
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Mon 4/5
11:00-18:15
1 stop12h 15m
Knoxville McGhee Tyson
Mon 11/5
16:00-08:10
1 stop11h 10m
£712
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Mon 5/1
10:25-17:16
2 stops35h 51m
Knoxville McGhee Tyson
Mon 12/1
18:09-08:20
2 stops33h 11m
£712
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Thu 22/1
05:40-16:49
2 stops16h 09m
Knoxville McGhee Tyson
Mon 26/1
14:19-14:00
2 stops18h 41m
£712
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Mon 4/5
07:00-19:41
2 stops17h 41m
Knoxville McGhee Tyson
Mon 11/5
19:20-10:25
2 stops34h 05m
£717
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Mon 4/5
14:50-09:11
2 stops23h 21m
Knoxville McGhee Tyson
Mon 11/5
10:05-08:10
1 stop17h 05m
£725
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 25/4
18:15-21:27
2 stops32h 12m
Knoxville McGhee Tyson
Sun 3/5
18:22-13:15
2 stops37h 53m
£725
Flights are sorted by cheapest return flights first.
Deals found on 7/12
Best time to book a flight from Manchester to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Manchester to Knoxville
How far ahead should I book a flight from Manchester to Knoxville?
Use this chart to determine the optimal time to book a return flight from Manchester to Knoxville. Price data was last updated on 5 December 2025.
The best time to book flights from Manchester to Knoxville is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Manchester to Knoxville?
Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £524). Flying from Manchester to Knoxville in July is currently the most expensive (average of £717). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAN to TYS?
Find hourly flight availability from Manchester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 9 December 2025.
One of the essential ways to save on airfare from Manchester to Knoxville is to remain as flexible as possible. Flights that are at midday tend to be the most expensive. A flight in the afternoon could potentially save you up to 27% on airfare.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated 9 December 2025.
Read reviews from past customers who have flown with KLM, Finnair, andVirgin Atlantic
from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Not literally sitting in the very last row in the middle
Related info for your journey
Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Manchester to Knoxville?
Airlines like British Airways, Delta, and Virgin Atlantic fly from Manchester to Knoxville in about 12h 15m. The time it takes to get you to your destination can typically vary by up to 12h 36m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.
What are the cheapest airlines flying from Manchester to Knoxville round-trip?
Currently priced at £551, United Airlines will fly you from Manchester to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Finnair and British Airways - these airlines can fly you to your destination from £556 and £574, respectively. You may be able to fly from Manchester to Knoxville for 26% less than the average price by searching for these airlines.
Can I find deals for business class flights from Manchester to Knoxville?
Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester to Knoxville?
Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £524). Flying from Manchester to Knoxville in July is currently the most expensive (average of £717). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on 9 December 2025.
Top 5 airlines flying from Manchester to Knoxville
Discover the top 5 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 December 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Manchester to Knoxville?
When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.
Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?
Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!
Can Cheapflights find flights from Manchester to Knoxville with no change fees?
Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.
Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?
Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.
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