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Cheap flights from Manchester to Knoxville from £605

MAN — TYS
2 Oct — 9 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Knoxville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Knoxville

Mon 19/1019:10 -
2 stops32h 12m
Mon 26/1018:23 -
2 stops20h 12m
Deal found 1/9£711
Fri 16/1019:10 -
2 stops32h 12m
Fri 23/1014:38 -
2 stops22h 52m
Deal found 1/9£751
Mon 9/1106:00 -
2 stops17h 46m
Thu 19/1111:34 -
2 stops21h 41m
Deal found 29/8£759
Wed 14/1009:20 -
2 stops19h 39m
Wed 21/1016:38 -
2 stops17h 52m
Deal found 30/8£777
Mon 9/1113:40 -
2 stops15h 19m
Thu 19/1114:40 -
1 stop15h 10m
Deal found 29/8£781
Wed 14/1010:40 -
1 stop14h 28m
Wed 21/1018:23 -
2 stops17h 22m
Deal found 30/8£808
Thu 1/1008:50 -
2 stops18h 53m
Thu 15/1011:35 -
2 stops17h 10m
Deal found 31/8£815
Thu 1/1013:00 -
1 stop15h 55m
Thu 15/1010:29 -
1 stop17h 21m
Deal found 31/8£828
Thu 17/913:00 -
1 stop15h 55m
Thu 1/1007:33 -
2 stops25h 27m
Deal found 29/8£835
Mon 19/1013:00 -
1 stop12h 08m
Mon 26/1019:45 -
2 stops16h 50m
Deal found 1/9£836

Find flight deals from Manchester to Knoxville

Round-trip from

£605

Popular in

August

Cheapest in

January

Average price

£805
Scandinavian Airlines
  • Scandinavian Airlines
  • 28/1-1/2
  • 4 total stops
  • 38h 14m total
  • Manchester to Knoxville
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£49 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Thu 28/1

10:10-23:46

2 stops18h 36m

Knoxville McGhee Tyson

Mon 1/2

17:57-18:35

2 stops19h 38m

£605

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Fri 16/10

19:10-22:22

2 stops32h 12m

Knoxville McGhee Tyson

Fri 23/10

14:38-18:30

2 stops22h 52m

£751

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Thu 1/10

13:00-23:55

1 stop15h 55m

Knoxville McGhee Tyson

Thu 15/10

12:06-08:25

2 stops15h 19m

£828

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Tue 15/9

06:55-19:43

2 stops17h 48m

Knoxville McGhee Tyson

Sun 20/9

20:13-19:20

2 stops18h 07m

£847

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Wed 14/10

10:35-09:45

2 stops28h 10m

Knoxville McGhee Tyson

Wed 21/10

09:45-09:50

2 stops19h 05m

£877

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Mon 12/10

06:05-17:08

2 stops16h 03m

Knoxville McGhee Tyson

Mon 19/10

13:35-09:50

2 stops15h 15m

£882
Fastest return journey

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sat 26/9

13:15-20:15

1 stop12h 00m

Knoxville McGhee Tyson

Sat 3/10

11:39-10:00

2 stops17h 21m

£887

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sat 26/9

06:05-20:19

2 stops19h 14m

Knoxville McGhee Tyson

Sat 3/10

15:45-09:50

2 stops61h 05m

£901

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Tue 15/9

13:00-23:55

1 stop15h 55m

Knoxville McGhee Tyson

Sun 20/9

09:37-07:15

1 stop16h 38m

£903

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Thu 15/10

13:00-23:59

1 stop15h 59m

Knoxville McGhee Tyson

Sun 25/10

12:06-06:40

1 stop14h 34m

£912

Flights are sorted by cheapest return flights first.

Deals found on 1/9

Sorted by cheapest first

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

What is the cheapest month to book a flight from Manchester to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £707). Flying from Manchester to Knoxville in August is currently the most expensive (average of £1,104). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Knoxville?

Airfare is below average for this route at the moment.

Manchester to Knoxville flights typically cost between £686 and £834 in January.
The cheapest return price found within the last 5 days was £605 on Scandinavian Airlines (28 Jan–1 Feb).

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown with Delta,Virgin Atlantic, andBritish Airways from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,543 reviews
Check prices

Entertainment

7.8

Boarding

8.1

Food

7.2

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.
Delta
7.8
Good
8,543 reviews
Delta
7.8
Good
8,543 reviews
Check prices

Entertainment

7.8

Boarding

8.1

Food

7.2

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.
Virgin Atlantic
7.4
Good
695 reviews
Delta
7.8
Good
8,543 reviews
Check prices

Entertainment

7.8

Boarding

8.1

Food

7.2

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.
British Airways
6.7
Okay
8,195 reviews
Delta
7.8
Good
8,543 reviews
Check prices

Entertainment

7.8

Boarding

8.1

Food

7.2

Comfort

7.8

Overall

7.8

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.

Related info for your journey

  • How long is the flight from Manchester to Knoxville?

    Airlines like Scandinavian Airlines and Virgin Atlantic fly from Manchester to Knoxville in about 15h 55m. The time it takes to get you to your destination can typically vary by up to 2h 41m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Knoxville round-trip?

    Currently priced at £567, British Airways will fly you from Manchester to Knoxville and back. In addition to British Airways, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Virgin Atlantic and Delta - these airlines can fly you to your destination from £610 and £702, respectively. You may be able to fly from Manchester to Knoxville for 34% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £707). Flying from Manchester to Knoxville in August is currently the most expensive (average of £1,104). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Manchester to Knoxville

AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£567Average£682FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£610Average£816FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
DeltaCheapest£702Average£812FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

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How does Cheapflights help users find flights from Manchester to Knoxville?

When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?

Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Knoxville with no change fees?

Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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