Cheap flights from Manchester to Knoxville from £599

MAN — TYS
13 Dec — 20 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Knoxville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Knoxville

Sun 6/1219:15 -
2 stops33h 42m
Wed 9/1214:36 -
2 stops22h 59m
Deal found 9/11£830
Wed 23/1220:40 -
2 stops29h 50m
Wed 30/1207:00 -
1 stop20h 45m
Deal found 8/11£896
Wed 23/1220:40 -
2 stops25h 50m
Wed 30/1210:11 -
2 stops18h 54m
Deal found 8/11£917
Tue 22/1219:15 -
2 stops33h 35m
Wed 30/1211:32 -
2 stops24h 13m
Deal found 10/11£917
Sun 27/1219:15 -
2 stops34h 00m
Sun 3/106:30 -
2 stops21h 45m
Deal found 12/11£987
Tue 22/1212:40 -
1 stop13h 44m
Wed 30/1218:55 -
2 stops16h 10m
Deal found 10/11£996
Wed 23/1212:40 -
1 stop16h 10m
Wed 30/1209:00 -
1 stop18h 45m
Deal found 8/11£1,021
Tue 22/1212:40 -
1 stop25h 51m
Wed 30/1210:11 -
1 stop17h 34m
Deal found 10/11£1,025
Sun 6/1220:10 -
2 stops27h 55m
Wed 9/1212:32 -
1 stop15h 13m
Deal found 9/11£1,300
Sun 27/1206:00 -
2 stops42h 49m
Sun 3/119:35 -
2 stops31h 55m
Deal found 12/11£1,517
Sun 6/1206:00 -
2 stops18h 47m
Wed 9/1207:05 -
2 stops20h 25m
Deal found 9/11£1,887
Wed 23/1211:25 -
3 stops38h 29m
Wed 30/1206:35 -
2 stops23h 05m
Deal found 8/11£2,152

Find flight deals from Manchester to Knoxville

Round-trip from

£601

Popular in

August

Cheapest in

May

Average price

£913
Scandinavian Airlines
  • Scandinavian Airlines
  • 3/3-7/3
  • 4 total stops
  • 40h 25m total
  • Manchester to Knoxville
Highest demand for flights based on searches. 3% potential increase in price (£24 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Wed 3/3

10:10-22:25

2 stops17h 15m

Knoxville McGhee Tyson

Sun 7/3

14:25-18:35

2 stops23h 10m

£599

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sun 6/12

19:15-23:57

2 stops33h 42m

Knoxville McGhee Tyson

Wed 9/12

14:36-18:35

2 stops22h 59m

£830

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Fri 22/1

10:15-00:28

2 stops19h 13m

Knoxville McGhee Tyson

Mon 25/1

16:20-16:30

2 stops19h 10m

£891

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sat 9/1

11:30-11:45

3 stops29h 15m

Knoxville McGhee Tyson

Sat 16/1

17:55-10:20

2 stops35h 25m

£926
Fastest return journey

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Tue 22/12

12:40-21:24

1 stop13h 44m

Knoxville McGhee Tyson

Wed 30/12

18:55-16:05

2 stops16h 10m

£996

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Wed 23/12

12:40-23:50

1 stop16h 10m

Knoxville McGhee Tyson

Wed 30/12

09:00-08:45

1 stop18h 45m

£1,021

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Tue 22/12

12:40-09:31

1 stop25h 51m

Knoxville McGhee Tyson

Wed 30/12

10:11-08:45

1 stop17h 34m

£1,025

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sat 9/1

06:00-21:33

2 stops20h 33m

Knoxville McGhee Tyson

Sat 16/1

17:00-08:20

1 stop10h 20m

£1,052

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sun 6/12

20:10-19:05

2 stops27h 55m

Knoxville McGhee Tyson

Wed 9/12

12:32-08:45

1 stop15h 13m

£1,300

ManchesterKnoxville

MAN Manchester - TYS Knoxville McGhee Tyson

MANTYS

Manchester

Sun 27/12

06:00-19:49

2 stops42h 49m

Knoxville McGhee Tyson

Sun 3/1

19:35-08:30

2 stops31h 55m

£1,517

Flights are sorted by cheapest return flights first.

Deals found on 12/11

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

What is the cheapest month to book a flight from Manchester to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £750). Flying from Manchester to Knoxville in August is currently the most expensive (average of £1,127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Knoxville?

Airfare is below average for this route at the moment.

Manchester to Knoxville flights typically cost between £870 and £978 in March.
The cheapest return price found within the last 5 days was £601 on Scandinavian Airlines (3 Mar–7 Mar).

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown with Delta,Virgin Atlantic, andBritish Airways from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.2

Crew

8.5

Comfort

7.8

Entertainment

7.8

Overall

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Crew

8.5

Comfort

7.8

Entertainment

7.8

Overall

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Crew

8.5

Comfort

7.8

Entertainment

7.8

Overall

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Crew

8.5

Comfort

7.8

Entertainment

7.8

Overall

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • How long is the flight from Manchester to Knoxville?

    Airlines like Scandinavian Airlines, British Airways, and United Airlines fly from Manchester to Knoxville in about 17h 15m. The time it takes to get you to your destination can typically vary by up to 12h. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Knoxville round-trip?

    Currently priced at £602, British Airways will fly you from Manchester to Knoxville and back. In addition to British Airways, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Virgin Atlantic and Delta - these airlines can fly you to your destination from £654 and £717, respectively. You may be able to fly from Manchester to Knoxville for 34% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £750). Flying from Manchester to Knoxville in August is currently the most expensive (average of £1,127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
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Top 3 airlines flying from Manchester to Knoxville

AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£602Average£696FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£654Average£855FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
DeltaCheapest£717Average£829FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

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When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

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Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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