Cheap flights from Manchester to Knoxville from £616
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TYS
4 Jan — 11 Jan1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in April or March, booked 80 days in advance, depart on a Friday or Tuesday and return on a Monday
Cheap flight deals from Manchester to Knoxville
Enter your travel dates to find the best prices.
Best flights from Manchester to Knoxville
Discover carefully curated flight deals from Manchester to Knoxville that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 5 December 2025.
Sat 17/106:45MAN - TYS
2 stops17h 42mLufthansa
Sat 24/114:25TYS - MAN
2 stops15h 05mLufthansa
Deal found 3/12£616
Thu 22/106:00MAN - TYS
2 stops19h 52mUnited Airlines
Mon 26/109:05TYS - MAN
2 stops26h 55mUnited Airlines
Deal found 2/12£639
Thu 22/105:40MAN - TYS
2 stops18h 06mBritish Airways
Mon 26/117:15TYS - MAN
2 stops16h 55mBritish Airways
Deal found 3/12£710
Sat 17/113:30MAN - TYS
1 stop15h 15mVirgin Atlantic
Sat 24/114:37TYS - MAN
2 stops14h 33mVirgin Atlantic
Deal found 3/12£737
Sat 25/411:00MAN - TYS
1 stop17h 46mDelta
Sun 3/507:07TYS - MAN
1 stop20h 03mDelta
Deal found 3/12£769
Sat 17/111:55MAN - TYS
3 stops34h 58mMultiple Airlines
Sat 24/117:59TYS - MAN
3 stops33h 46mMultiple Airlines
Deal found 3/12£1,070
Sat 25/411:10MAN - TYS
2 stops59h 18mLufthansa
Sun 3/514:00TYS - MAN
2 stops39h 25mLufthansa
Deal found 3/12£708
Sat 17/106:05MAN - TYS
3 stops18h 22mUnited Airlines
Sat 24/113:59TYS - MAN
2 stops17h 11mUnited Airlines
Deal found 3/12£713
Sat 25/407:00MAN - TYS
2 stops19h 27mBritish Airways
Sun 3/520:44TYS - MAN
2 stops35h 31mBritish Airways
Deal found 4/12£722
Sat 25/411:00MAN - TYS
1 stop17h 46mVirgin Atlantic
Sun 3/514:30TYS - MAN
2 stops14h 50mVirgin Atlantic
Deal found 4/12£752
Last-minute flights from Manchester to Knoxville
Discover last-minute flight deals from Manchester to Knoxville. Data last updated 5 December 2025 and is based on user searches.
Sat 17/106:45MAN - TYS
2 stops17h 42mLufthansa
Sat 24/114:25TYS - MAN
2 stops15h 05mLufthansa
Deal found 3/12£616
Sat 17/106:05MAN - TYS
3 stops18h 22mUnited Airlines
Sat 24/113:59TYS - MAN
2 stops17h 11mUnited Airlines
Deal found 3/12£713
Sat 17/113:30MAN - TYS
1 stop15h 15mVirgin Atlantic
Sat 24/114:37TYS - MAN
1 stop14h 53mVirgin Atlantic
Deal found 3/12£731
Sat 17/111:55MAN - TYS
3 stops34h 58mMultiple Airlines
Sat 24/117:59TYS - MAN
3 stops33h 46mMultiple Airlines
Deal found 3/12£1,070
Sat 17/118:30MAN - TYS
4 stops49h 19mEthiopian Air
Sat 24/114:25TYS - MAN
4 stops36h 05mEthiopian Air
Deal found 3/12£3,015
Thu 22/106:00MAN - TYS
2 stops19h 52mUnited Airlines
Mon 26/109:05TYS - MAN
2 stops26h 55mUnited Airlines
Deal found 2/12£639
Thu 22/105:40MAN - TYS
2 stops18h 06mBritish Airways
Mon 26/117:15TYS - MAN
2 stops16h 55mBritish Airways
Deal found 3/12£710
Thu 22/118:30MAN - TYS
4 stops49h 19mEthiopian Air
Mon 26/114:25TYS - MAN
4 stops36h 55mEthiopian Air
Deal found 2/12£2,789
Find flight deals from Manchester to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 5 December 2025.
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 5 December 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.
Fly from
Manchester
Fly to
Knoxville
Route
Depart
Return
Price
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 17/1
06:45-19:27
2 stops17h 42m
Knoxville McGhee Tyson
Sat 24/1
14:25-10:30
2 stops15h 05m
£616
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Thu 22/1
06:00-20:52
2 stops19h 52m
Knoxville McGhee Tyson
Mon 26/1
09:05-17:00
2 stops26h 55m
£639
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 25/4
11:10-17:28
2 stops59h 18m
Knoxville McGhee Tyson
Sun 3/5
14:00-10:25
2 stops39h 25m
£708
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Thu 22/1
05:40-18:46
2 stops18h 06m
Knoxville McGhee Tyson
Mon 26/1
17:15-15:10
2 stops16h 55m
£710
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 17/1
06:05-19:27
3 stops18h 22m
Knoxville McGhee Tyson
Sat 24/1
13:59-12:10
2 stops17h 11m
£713
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 25/4
07:00-21:27
2 stops19h 27m
Knoxville McGhee Tyson
Sun 3/5
20:44-13:15
2 stops35h 31m
£722
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 17/1
13:30-23:45
1 stop15h 15m
Knoxville McGhee Tyson
Sat 24/1
14:37-10:10
2 stops14h 33m
£737
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 25/4
11:00-23:46
1 stop17h 46m
Knoxville McGhee Tyson
Sun 3/5
14:30-10:20
2 stops14h 50m
£752
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 25/4
11:00-23:46
1 stop17h 46m
Knoxville McGhee Tyson
Sun 3/5
07:07-08:10
1 stop20h 03m
£769
ManchesterKnoxville
MAN - TYS
MANTYS
Manchester
Sat 17/1
11:55-17:53
3 stops34h 58m
Knoxville McGhee Tyson
Sat 24/1
17:59-08:45
3 stops33h 46m
£1,070
Flights are sorted by cheapest return flights first.
Deals found on 3/12
Best time to book a flight from Manchester to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Manchester to Knoxville
How far ahead should I book a flight from Manchester to Knoxville?
Use this chart to determine the optimal time to book a return flight from Manchester to Knoxville. Price data was last updated on 28 November 2025.
The best time to book flights from Manchester to Knoxville is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Manchester to Knoxville?
Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £523). Flying from Manchester to Knoxville in July is currently the most expensive (average of £719). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAN to TYS?
Find hourly flight availability from Manchester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 5 December 2025.
One of the essential ways to save on airfare from Manchester to Knoxville is to remain as flexible as possible. Flights that are at midday tend to be the most expensive. A flight in the afternoon could potentially save you up to 27% on airfare.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated 5 December 2025.
Read reviews from past customers who have flown with KLM, Finnair, andVirgin Atlantic
from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Not literally sitting in the very last row in the middle
Related info for your journey
Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Manchester to Knoxville?
Airlines like Lufthansa, United Airlines, and British Airways fly from Manchester to Knoxville in about 17h 42m. The time it takes to get you to your destination can typically vary by up to 2h 10m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.
What are the cheapest airlines flying from Manchester to Knoxville round-trip?
Currently priced at £550, United Airlines will fly you from Manchester to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Finnair and British Airways - these airlines can fly you to your destination from £555 and £573, respectively. You may be able to fly from Manchester to Knoxville for 27% less than the average price by searching for these airlines.
Can I find deals for business class flights from Manchester to Knoxville?
Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester to Knoxville?
Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £523). Flying from Manchester to Knoxville in July is currently the most expensive (average of £719). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on 5 December 2025.
Top 5 airlines flying from Manchester to Knoxville
Discover the top 5 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 5 December 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Manchester to Knoxville?
When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.
Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?
Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!
Can Cheapflights find flights from Manchester to Knoxville with no change fees?
Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.
Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?
Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.
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