Cheap flights from Manchester to Knoxville from £745

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/11. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TYS
29 May — 5 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Knoxville

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 April 2026.

Tue 24/1109:40
MAN
-
TYS
2 stops16h 24m
British Airways
Thu 3/1213:14
TYS
-
MAN
2 stops20h 06m
British Airways
Deal found 27/4£745
Tue 24/1113:30
MAN
-
TYS
1 stop15h 16m
Virgin Atlantic
Thu 3/1216:00
TYS
-
MAN
1 stop13h 30m
Virgin Atlantic
Deal found 24/4£770
Mon 14/908:00
MAN
-
TYS
2 stops18h 54m
British Airways
Tue 22/906:21
TYS
-
MAN
2 stops22h 29m
British Airways
Deal found 27/4£776
Tue 9/613:00
MAN
-
TYS
1 stop13h 49m
Virgin Atlantic
Tue 16/611:55
TYS
-
MAN
1 stop15h 55m
Virgin Atlantic
Deal found 25/4£809
Mon 14/913:00
MAN
-
TYS
1 stop15h 47m
Virgin Atlantic
Tue 22/916:00
TYS
-
MAN
1 stop11h 50m
Virgin Atlantic
Deal found 27/4£818
Thu 11/613:00
MAN
-
TYS
1 stop12h 14m
Virgin Atlantic
Thu 18/611:55
TYS
-
MAN
1 stop15h 55m
Virgin Atlantic
Deal found 27/4£842

Find flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 April 2026.

Round-trip from

£776

One-way from

£747

Popular in

July

Cheapest in

March

Average price

£700
British Airways
  • British Airways
  • 14/9-22/9
  • 4 total stops
  • 41h 23m total
  • Manchester to Knoxville
Virgin Atlantic
  • Virgin Atlantic
  • 4/8
  • 1 total stop
  • 15h 52m total
  • Manchester to Knoxville
Highest demand for flights based on searches. 11% potential increase in price (£72 potential increase over avg. return price).
Cheapest flight prices on average. 1% potential price decrease (£11 potential savings vs. average return price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 April 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

08:00-21:54

2 stops18h 54m

Knoxville McGhee Tyson

Tue 22/9

06:21-09:50

2 stops22h 29m

£776

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

13:00-23:47

1 stop15h 47m

Knoxville McGhee Tyson

Tue 22/9

17:57-16:55

2 stops17h 58m

£809

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 9/6

13:00-21:49

1 stop13h 49m

Knoxville McGhee Tyson

Tue 16/6

11:55-08:50

1 stop15h 55m

£809

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 11/6

12:10-23:57

2 stops16h 47m

Knoxville McGhee Tyson

Thu 18/6

13:59-08:50

1 stop13h 51m

£850

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 10/6

06:05-10:42

2 stops33h 37m

Knoxville McGhee Tyson

Wed 17/6

06:30-06:30

2 stops43h 00m

£935
Fastest return journey

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 30/7

13:00-20:05

1 stop12h 05m

Knoxville McGhee Tyson

Wed 9/12

12:00-07:00

2 stops14h 00m

£968

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 11/6

21:10-21:49

3 stops29h 39m

Knoxville McGhee Tyson

Thu 18/6

15:54-18:30

2 stops21h 36m

£1,173

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 30/7

21:25-21:58

3 stops29h 33m

Knoxville McGhee Tyson

Wed 9/12

16:00-18:35

2 stops21h 35m

£1,236

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

06:05-20:28

3 stops19h 23m

Knoxville McGhee Tyson

Tue 22/9

10:00-06:30

3 stops15h 30m

£1,443
Cheapest one-way
Fastest single journey

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 4/8

13:00-23:52

1 stop15h 52m

£747

Flights are sorted by cheapest return flights first.

Deals found on 24/4

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester to Knoxville?

The best time to book flights from Manchester to Knoxville is 78 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester to Knoxville?

Currently, March is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £657). Flying from Manchester to Knoxville in July is currently the most expensive (average of £882). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated 29 April 2026.
Read reviews from past customers who have flown with Delta,Finnair, andUnited Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Manchester to Knoxville?

    Airlines like British Airways, Delta, and Virgin Atlantic fly from Manchester to Knoxville in about 13h 49m. The time it takes to get you to your destination can typically vary by up to 5h 05m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Knoxville round-trip?

    Currently priced at £544, United Airlines will fly you from Manchester to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from British Airways and Finnair - these airlines can fly you to your destination from £566 and £577, respectively. You may be able to fly from Manchester to Knoxville for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Knoxville?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £657). Flying from Manchester to Knoxville in July is currently the most expensive (average of £882). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee

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Top 5 airlines flying from Manchester to Knoxville

Discover the top 5 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 April 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£544Average£639FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapest£566Average£638FlexibilityNo cancel feeOn-time70%
Search British Airways flights
FinnairCheapest£577Average£638FlexibilityNo cancel feeOn-time76%
Search Finnair flights
Virgin AtlanticCheapest£606Average£752FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
DeltaCheapest£704Average£814FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Manchester to Knoxville?

When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?

Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Knoxville with no change fees?

Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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