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Cheap flights from Manchester to Knoxville from £501

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TYS
16 Nov — 23 Nov1
1 adult
1 adult, Economy

Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in April or November, booked 12 days in advance, depart on a Friday or Tuesday and return on a Monday

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Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 October 2025.

Wed 3/1206:00MAN - TYS
2 stops18h 29mUnited Airlines
Wed 10/1207:00TYS - MAN
2 stops20h 40mUnited Airlines
Deal found 15/10£697
Thu 27/1105:50MAN - TYS
2 stops18h 04mVirgin Atlantic
Thu 11/1219:59TYS - MAN
2 stops15h 06mVirgin Atlantic
Deal found 17/10£704
Fri 31/1021:30MAN - TYS
2 stops24h 16mBritish Airways
Thu 6/1120:04TYS - MAN
2 stops15h 26mBritish Airways
Deal found 16/10£727
Fri 14/1113:25MAN - TYS
1 stop15h 16mVirgin Atlantic
Fri 21/1120:07TYS - MAN
2 stops53h 33mVirgin Atlantic
Deal found 14/10£728
Thu 27/1107:45MAN - TYS
3 stops21h 14mAmerican Airlines
Thu 11/1218:29TYS - MAN
2 stops14h 51mAmerican Airlines
Deal found 17/10£738
Fri 31/1013:25MAN - TYS
1 stop13h 42mMultiple Airlines
Thu 6/1115:59TYS - MAN
2 stops19h 36mMultiple Airlines
Deal found 16/10£746
Thu 13/1113:00MAN - TYS
2 stops53h 19mUnited Airlines
Thu 20/1109:50TYS - MAN
2 stops19h 30mUnited Airlines
Deal found 15/10£749
Fri 31/1013:25MAN - TYS
1 stop28h 17mDelta
Thu 6/1108:15TYS - MAN
1 stop21h 15mDelta
Deal found 16/10£757
Thu 27/1113:30MAN - TYS
1 stop26h 15mDelta
Thu 11/1215:56TYS - MAN
1 stop13h 34mDelta
Deal found 17/10£775
Thu 13/1113:30MAN - TYS
1 stop15h 11mVirgin Atlantic
Thu 20/1115:53TYS - MAN
1 stop13h 37mVirgin Atlantic
Deal found 15/10£788

Cheap flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 17 October 2025.

Round-trip from

£681

One-way from

£501

Popular in

July

Cheapest in

April

Average price

£855
United Airlines
  • United Airlines
  • 6/3-10/3
  • 4 total stops
  • 38h 16m total
  • Manchester to Knoxville
Search Deals
27/3
  • 27/3
  • 3 total stops
  • 44h 52m total
  • Manchester to Knoxville
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£85 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 October 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Manchester

Fly to

Knoxville

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 6/3

06:05-20:54

2 stops19h 49m

Knoxville McGhee Tyson

Tue 10/3

13:53-12:20

2 stops18h 27m

£681

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 3/12

06:00-19:29

2 stops18h 29m

Knoxville McGhee Tyson

Wed 10/12

07:00-08:40

2 stops20h 40m

£697

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 27/11

05:50-18:54

2 stops18h 04m

Knoxville McGhee Tyson

Thu 11/12

19:59-16:05

2 stops15h 06m

£704

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 28/2

06:05-19:29

2 stops18h 24m

Knoxville McGhee Tyson

Sat 7/3

07:00-12:10

2 stops24h 10m

£710

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 6/3

13:25-20:38

1 stop12h 13m

Knoxville McGhee Tyson

Tue 10/3

19:20-18:40

2 stops19h 20m

£724

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 31/10

21:30-17:46

2 stops24h 16m

Knoxville McGhee Tyson

Thu 6/11

20:04-16:30

2 stops15h 26m

£727

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 27/3

20:10-13:02

3 stops44h 52m

£501

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 27/3

13:25-21:43

1 stop12h 18m

£885

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 27/3

18:30-14:42

4 stops48h 12m

£1,904

Flights are sorted by cheapest return flights first.

Deals found on 15/10

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester to Knoxville?

Use this chart to determine the optimal time to book a return flight from Manchester to Knoxville. Price data was last updated on 10 October 2025.

The best time to book flights from Manchester to Knoxville is 12 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £520). Flying from Manchester to Knoxville in July is currently the most expensive (average of £715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to TYS?

Find hourly flight availability from Manchester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 October 2025.

One of the essential ways to save on airfare from Manchester to Knoxville is to remain as flexible as possible. Flights that are at midday tend to be the most expensive. A flight in the afternoon could potentially save you up to 27% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated 17 October 2025.
Read reviews from past customers who have flown with KLM, Finnair, andVirgin Atlantic from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,404 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,404 reviews
KLM
7.7
Good
1,404 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Finnair
7.6
Good
1,332 reviews
KLM
7.7
Good
1,404 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Virgin Atlantic
7.5
Good
670 reviews
KLM
7.7
Good
1,404 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
United Airlines
7.4
Good
8,982 reviews
KLM
7.7
Good
1,404 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6.7
Okay
7,457 reviews
KLM
7.7
Good
1,404 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Knoxville?

    Airlines like United Airlines and Virgin Atlantic fly from Manchester to Knoxville in about 18h 04m. The time it takes to get you to your destination can typically vary by up to 1h 45m. There are 3961 mi between Manchester and Knoxville. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Knoxville round-trip?

    Currently priced at £546, United Airlines will fly you from Manchester to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Finnair and British Airways - these airlines can fly you to your destination from £567 and £572, respectively. You may be able to fly from Manchester to Knoxville for 29% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Manchester to Knoxville (average of £520). Flying from Manchester to Knoxville in July is currently the most expensive (average of £715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
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Top 6 airlines flying from Manchester to Knoxville

Discover the top 6 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 October 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£546Average£715FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
FinnairCheapest£567Average£604FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£572Average£667FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapest£581Average£666FlexibilityNo cancel feeOn-time77%
Search Air France flights
Virgin AtlanticCheapest£583Average£743FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£590Average£732FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Manchester to Knoxville?

When you search for this flight from Manchester to Knoxville, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Knoxville?

Cheapflights helps you find that perfect flight to Knoxville from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Knoxville with no change fees?

Yes, we can. To see specific flights from Manchester to Knoxville with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Knoxville become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Knoxville flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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