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Cheap flights from Knoxville to Manchester from £715

TYS — MAN
6 Oct — 13 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Knoxville to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Knoxville to Manchester

Tue 20/1018:23 -
1 stop31h 52m
Tue 27/1012:40 -
1 stop13h 42m
Deal found 5/9£715
Wed 4/1111:45 -
2 stops16h 55m
Fri 13/1114:55 -
1 stop14h 04m
Deal found 3/9£719
Tue 20/1017:18 -
2 stops15h 42m
Tue 27/1012:40 -
1 stop13h 42m
Deal found 5/9£723
Sun 11/1012:06 -
1 stop14h 09m
Tue 20/1013:00 -
1 stop14h 22m
Deal found 4/9£726
Mon 12/1007:26 -
2 stops19h 49m
Tue 20/1012:10 -
2 stops26h 24m
Deal found 4/9£729
Wed 4/1109:45 -
3 stops19h 35m
Fri 13/1106:10 -
3 stops22h 49m
Deal found 3/9£734
Sun 11/1011:35 -
2 stops17h 20m
Mon 19/1020:15 -
2 stops27h 05m
Deal found 4/9£739
Sat 10/1019:25 -
2 stops33h 25m
Tue 20/1006:05 -
2 stops19h 44m
Deal found 4/9£742
Fri 4/1218:17 -
1 stop11h 13m
Sat 12/1212:40 -
1 stop14h 37m
Deal found 5/9£746
Fri 4/1214:35 -
2 stops14h 30m
Sat 12/1212:40 -
1 stop12h 34m
Deal found 5/9£750

Find flight deals from Knoxville to Manchester

Round-trip from

£715

Popular in

May

Cheapest in

January

Average price

£762
Virgin Atlantic
  • Virgin Atlantic
  • 20/10-27/10
  • 2 total stops
  • 45h 34m total
  • Knoxville to Manchester
Search Deals
Highest demand for flights based on searches. 22% potential increase in price (£169 potential increase over avg. return price).
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Cheapest flight prices on average. 9% potential price decrease (£54 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

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Cheapest return flight

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 12/10

08:35-08:50

1 stop19h 15m

Manchester

Tue 20/10

15:00-10:54

2 stops24h 54m

£729

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

06:45-09:00

2 stops21h 15m

Manchester

Sat 14/11

11:30-20:54

2 stops38h 24m

£786
Fastest return journey

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

14:38-16:05

2 stops20h 27m

Manchester

Sat 14/11

12:40-22:12

1 stop14h 32m

£794

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 16/11

06:45-09:00

2 stops21h 15m

Manchester

Wed 18/11

06:10-16:59

2 stops15h 49m

£840

Flights are sorted by cheapest return flights first.

Deals found on 4/9

Sorted by cheapest first

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £460). Flying from Knoxville to Manchester in May is currently the most expensive (average of £1,602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • How long is the flight from Knoxville to Manchester?

    A quick flight from Knoxville to Manchester can take about 19h 15m. Delta provides one of the quickest options available for as low as £729. There are 3961 mi between Knoxville and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £460). Flying from Knoxville to Manchester in May is currently the most expensive (average of £1,602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Telford
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