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Cheap flights from Knoxville to Manchester from £606

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
22 Aug — 29 Aug1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Knoxville to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 July 2026.

Wed 2/1208:30
TYS
-
MAN
2 stops19h 10m
United Airlines
Fri 4/1206:10
MAN
-
TYS
2 stops37h 32m
United Airlines
Deal found 21/7£606
Wed 4/1119:20
TYS
-
MAN
2 stops23h 00m
Lufthansa
Wed 11/1106:25
MAN
-
TYS
2 stops22h 31m
Lufthansa
Deal found 22/7£672
Wed 4/1116:37
TYS
-
MAN
1 stop11h 08m
Virgin Atlantic
Wed 11/1112:40
MAN
-
TYS
1 stop14h 05m
Virgin Atlantic
Deal found 22/7£677
Wed 4/1109:45
TYS
-
MAN
3 stops17h 30m
Air Canada
Wed 11/1106:10
MAN
-
TYS
3 stops22h 46m
Air Canada
Deal found 22/7£693
Wed 4/1109:45
TYS
-
MAN
2 stops17h 30m
Multiple Airlines
Wed 11/1106:10
MAN
-
TYS
3 stops22h 46m
Multiple Airlines
Deal found 22/7£715
Wed 2/909:45
TYS
-
MAN
2 stops19h 40m
United Airlines
Wed 9/909:00
MAN
-
TYS
2 stops42h 49m
United Airlines
Deal found 19/7£728
Fri 6/1107:00
TYS
-
MAN
2 stops20h 15m
United Airlines
Sat 14/1111:30
MAN
-
TYS
2 stops34h 32m
United Airlines
Deal found 22/7£748
Thu 5/1118:21
TYS
-
MAN
1 stop11h 29m
Virgin Atlantic
Sat 14/1112:40
MAN
-
TYS
1 stop16h 06m
Virgin Atlantic
Deal found 22/7£752

Find flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 23 July 2026.

Round-trip from

£606

Popular in

August

Cheapest in

January

Average price

£1,007
United Airlines
  • United Airlines
  • 2/12-4/12
  • 4 total stops
  • 56h 42m total
  • Knoxville to Manchester
Search Deals
Highest demand for flights based on searches. 27% potential increase in price (£212 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£27 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 23 July 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 2/12

08:30-10:20

2 stops20h 50m

Manchester

Fri 4/12

06:10-16:49

2 stops15h 39m

£668
Fastest return journey

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 4/11

11:45-09:40

2 stops16h 55m

Manchester

Wed 11/11

12:40-21:45

1 stop14h 05m

£680

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 2/9

09:45-10:25

2 stops19h 40m

Manchester

Wed 9/9

06:05-22:49

3 stops21h 44m

£745

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

10:48-10:20

2 stops18h 32m

Manchester

Sat 14/11

11:30-17:02

2 stops34h 32m

£748

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

08:30-08:15

2 stops42h 45m

Manchester

Sat 14/11

11:30-20:44

2 stops38h 14m

£748

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

18:21-16:05

2 stops16h 44m

Manchester

Sat 14/11

12:40-23:46

1 stop16h 06m

£757

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

06:00-10:30

1 stop23h 30m

Manchester

Sat 14/11

12:40-20:40

1 stop13h 00m

£758

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 4/9

05:45-10:25

2 stops23h 40m

Manchester

Fri 11/9

09:00-13:18

2 stops33h 18m

£765

Flights are sorted by cheapest return flights first.

Deals found on 22/7

Sorted by cheapest first

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £465). Flying from Knoxville to Manchester in August is currently the most expensive (average of £1,115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester?

    A quick flight from Knoxville to Manchester can take about 16h 55m. United Airlines provides one of the quickest options available for as low as £680. There are 3961 mi between Knoxville and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £465). Flying from Knoxville to Manchester in August is currently the most expensive (average of £1,115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Bradford
Llandudno
Southport
Lincoln
Harrogate
Derby
Stoke-on-Trent
Telford
Salford
Shrewsbury
Warrington
Otley
Burnley
Preston
Wakefield
Lancaster
Macclesfield
Huddersfield
Bolton

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