Find flights
When to book
FAQs

Cheap flights from Knoxville to Manchester from £678

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
24 May — 31 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Knoxville to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 April 2026.

Tue 13/1005:45
TYS
-
MAN
2 stops19h 45m
United Airlines
Thu 29/1011:50
MAN
-
TYS
2 stops32h 59m
United Airlines
Deal found 19/4£678
Tue 13/1014:17
TYS
-
MAN
2 stops14h 33m
American Airlines
Thu 29/1008:50
MAN
-
TYS
2 stops16h 48m
American Airlines
Deal found 19/4£689
Mon 11/510:49
TYS
-
MAN
2 stops18h 36m
United Airlines
Fri 22/506:05
MAN
-
TYS
2 stops15h 55m
United Airlines
Deal found 19/4£751
Fri 6/1116:15
TYS
-
MAN
2 stops17h 05m
American Airlines
Sat 14/1108:50
MAN
-
TYS
2 stops19h 04m
American Airlines
Deal found 21/4£754
Tue 12/519:18
TYS
-
MAN
2 stops34h 07m
United Airlines
Fri 22/506:05
MAN
-
TYS
2 stops15h 55m
United Airlines
Deal found 19/4£755
Sun 10/514:25
TYS
-
MAN
2 stops15h 00m
United Airlines
Fri 22/506:05
MAN
-
TYS
2 stops15h 55m
United Airlines
Deal found 19/4£760
Tue 13/1008:47
TYS
-
MAN
2 stops18h 33m
Delta
Thu 29/1013:30
MAN
-
TYS
1 stop12h 15m
Delta
Deal found 19/4£761
Mon 24/817:57
TYS
-
MAN
2 stops18h 13m
Lufthansa
Sat 29/810:35
MAN
-
TYS
2 stops18h 22m
Lufthansa
Deal found 19/4£787
Mon 11/510:49
TYS
-
MAN
2 stops18h 36m
United Airlines
Thu 28/506:05
MAN
-
TYS
2 stops22h 49m
United Airlines
Deal found 19/4£794
Mon 24/817:57
TYS
-
MAN
3 stops31h 33m
United Airlines
Sat 29/806:05
MAN
-
TYS
2 stops15h 54m
United Airlines
Deal found 19/4£795
Sat 9/513:52
TYS
-
MAN
2 stops22h 28m
United Airlines
Fri 22/506:05
MAN
-
TYS
2 stops15h 55m
United Airlines
Deal found 19/4£797

Find flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 April 2026.

Round-trip from

£678

Popular in

September

Cheapest in

January

Average price

£584
United Airlines
  • United Airlines
  • 13/10-29/10
  • 4 total stops
  • 52h 44m total
  • Knoxville to Manchester
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£72 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£27 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 April 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 24/8

17:57-06:30

3 stops31h 33m

Manchester

Sat 29/8

06:05-16:59

2 stops15h 54m

£795

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 12/5

19:18-10:25

2 stops34h 07m

Manchester

Mon 25/5

11:10-20:56

2 stops38h 46m

£823
Fastest return journey

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 24/8

14:30-10:20

2 stops14h 50m

Manchester

Sat 29/8

13:15-20:42

1 stop12h 27m

£833

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/6

05:45-06:30

2 stops43h 45m

Manchester

Tue 16/6

06:05-20:56

2 stops19h 51m

£834

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 24/8

07:07-08:50

1 stop20h 43m

Manchester

Sat 29/8

13:15-23:50

1 stop15h 35m

£854

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 25/5

10:10-09:50

2 stops18h 40m

Manchester

Mon 8/6

06:05-23:54

2 stops22h 49m

£879

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 7/5

11:56-08:50

1 stop15h 54m

Manchester

Sun 17/5

11:15-23:56

1 stop17h 41m

£886

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 7/5

17:59-14:00

2 stops15h 01m

Manchester

Sun 17/5

11:15-20:28

1 stop14h 13m

£890

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 26/5

10:25-08:50

1 stop17h 25m

Manchester

Wed 10/6

10:40-23:54

1 stop18h 14m

£896

Flights are sorted by cheapest return flights first.

Deals found on 19/4

Sorted by cheapest first

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £461). Flying from Knoxville to Manchester in September is currently the most expensive (average of £1,075). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Knoxville to Manchester?

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester?

    A quick flight from Knoxville to Manchester can take about 14h 50m. United Airlines provides one of the quickest options available for as low as £833. There are 3961 mi between Knoxville and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £461). Flying from Knoxville to Manchester in September is currently the most expensive (average of £1,075). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Bradford
Lincoln
Llandudno
Derby
Harrogate
Southport
Stoke-on-Trent
Otley
Warrington
Lancaster
Telford
Salford
Huddersfield
Shrewsbury
Preston
Wakefield
Bolton
Wilmslow
Macclesfield

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Knoxville to Manchester?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Manchester from Knoxville today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Knoxville to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from Knoxville.

Can Cheapflights find flights from Knoxville to Manchester with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Knoxville to Manchester flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Knoxville to Manchester become cheaper?

Not ready to book yet? You can track prices for flights from Knoxville to Manchester on Cheapflights with our Price Alert feature and get notified when better prices are available.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.