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Cheap flights from Santiago to Lisbon from £416

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — LIS
9 Jan — 16 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Lisbon

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Lisbon
Explore the most affordable flight options available from Santiago to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 December 2025.

Mon 8/1223:55SCL - LIS
1 stop20h 30mIberia
Mon 15/1208:20LIS - SCL
1 stop16h 55mIberia
Deal found 7/12£866
Tue 23/1212:25SCL - LIS
2 stops47h 25mBritish Airways
Mon 12/110:35LIS - SCL
2 stops28h 05mBritish Airways
Deal found 9/12£996
Tue 23/1212:35SCL - LIS
2 stops43h 00mMultiple Airlines
Mon 12/118:30LIS - SCL
1 stop18h 10mMultiple Airlines
Deal found 9/12£1,014
Fri 26/1212:35SCL - LIS
2 stops43h 00mMultiple Airlines
Fri 16/116:10LIS - SCL
1 stop20h 30mMultiple Airlines
Deal found 8/12£1,069
Tue 23/1212:35SCL - LIS
2 stops43h 00mKLM
Mon 12/111:25LIS - SCL
2 stops26h 40mKLM
Deal found 8/12£1,087
Fri 26/1212:35SCL - LIS
2 stops43h 00mKLM
Fri 16/111:25LIS - SCL
2 stops25h 15mKLM
Deal found 9/12£1,089
Tue 30/1223:55SCL - LIS
1 stop15h 10mMultiple Airlines
Mon 12/115:50LIS - SCL
2 stops22h 50mMultiple Airlines
Deal found 10/12£1,092
Tue 9/1212:35SCL - LIS
2 stops23h 00mKLM
Tue 16/1211:25LIS - SCL
2 stops26h 40mKLM
Deal found 7/12£1,127
Fri 19/1212:35SCL - LIS
2 stops43h 00mKLM
Thu 8/111:25LIS - SCL
2 stops26h 40mKLM
Deal found 9/12£1,131

Find flight deals from Santiago to Lisbon

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Lisbon (LIS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 December 2025.

Round-trip from

£651

One-way from

£429

Popular in

July

Cheapest in

November

Average price

£709
Iberia
  • Iberia
  • 3/4-17/4
  • 2 total stops
  • 46h 15m total
  • Santiago to Lisbon
Search Deals
United Airlines
  • United Airlines
  • 8/3
  • 2 total stops
  • 39h 05m total
  • Santiago to Lisbon
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (£67 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£12 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 December 2025.
Use the filters below to find and compare flights from Santiago to Lisbon that are best for you.

Fly from

Santiago

Fly to

Lisbon

Route

Depart

Return

Price

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Fri 3/4

16:00-23:10

1 stop27h 10m

Lisbon Humberto Delgado

Fri 17/4

06:35-20:40

1 stop19h 05m

£651

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 19/5

15:00-23:00

1 stop27h 00m

Lisbon Humberto Delgado

Sat 13/6

16:25-07:45

1 stop20h 20m

£687

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Mon 25/5

10:55-23:10

2 stops31h 15m

Lisbon Humberto Delgado

Sat 13/6

16:25-07:45

1 stop20h 20m

£697

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Mon 25/5

10:55-23:10

2 stops31h 15m

Lisbon Humberto Delgado

Thu 11/6

15:00-07:30

1 stop21h 30m

£697

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Fri 24/4

15:00-23:10

1 stop27h 10m

Lisbon Humberto Delgado

Sun 3/5

12:30-07:25

1 stop23h 55m

£699

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Mon 25/5

10:55-23:10

2 stops31h 15m

Lisbon Humberto Delgado

Mon 8/6

07:15-07:30

1 stop29h 15m

£716

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 22/1

22:45-08:10

2 stops30h 25m

Lisbon Humberto Delgado

Thu 29/1

19:50-08:50

2 stops40h 00m

£732

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 24/5

15:00-10:05

1 stop38h 05m

Lisbon Humberto Delgado

Sat 13/6

16:25-07:45

1 stop20h 20m

£747

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 19/5

15:00-23:00

1 stop27h 00m

Lisbon Humberto Delgado

Thu 11/6

18:40-20:40

2 stops31h 00m

£755

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Mon 25/5

10:55-23:10

2 stops31h 15m

Lisbon Humberto Delgado

Tue 9/6

16:30-20:40

2 stops33h 10m

£766

Flights are sorted by cheapest return flights first.

Deals found on 9/12

Showing 1-10 of 20 results
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Best time to book a flight from Santiago to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Lisbon

How far ahead should I book a flight from Santiago to Lisbon?

Use this chart to determine the optimal time to book a return flight from Santiago to Lisbon. Price data was last updated on 5 December 2025.

To ensure you get the cheapest price possible for a flight from Santiago to Lisbon, you should look to book at least 58 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santiago to Lisbon?

Currently, March is the cheapest month in which you can book a flight from Santiago to Lisbon (average of £505). Flying from Santiago to Lisbon in September is currently the most expensive (average of £684). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Lisbon?

    There are many flights that can get you from Santiago to Lisbon in 27h. Fly via British Airways to get the fastest option. The distance between Santiago and Lisbon is about 6355 mi.

  • Can I find deals for flights from Santiago to Lisbon that include hotel bookings?

    Yes. In addition to deals on Santiago to Lisbon flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Lisbon.

  • Can I find deals for business class flights from Santiago to Lisbon?

    Yes. Cheapflights offers flight deals from Santiago to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Lisbon?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Lisbon (average of £505). Flying from Santiago to Lisbon in September is currently the most expensive (average of £684). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Madeira
Setúbal
Oeiras
Fátima
Estoril
Almada
Beja
Sintra
Costa da Caparica
Óbidos
Nazaré
Sesimbra
Peniche

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Yes! Cheapflights helps users easily find flights from Santiago to Lisbon with no change fees.

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