Cheap flights from Santiago to Lisbon from £436

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/3. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — LIS
10 Apr — 17 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Lisbon

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Lisbon
Explore the most affordable flight options available from Santiago to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 March 2026.

Tue 11/816:05
SCL
-
LIS
1 stop22h 10m
Multiple Airlines
Tue 1/920:05
LIS
-
SCL
1 stop29h 30m
Multiple Airlines
Deal found 8/3£650
Thu 1/1011:40
SCL
-
LIS
1 stop31h 45m
Iberia
Mon 12/1012:30
LIS
-
SCL
1 stop37h 10m
Iberia
Deal found 10/3£667
Mon 5/1007:20
SCL
-
LIS
1 stop19h 50m
LATAM Airlines
Mon 2/1114:50
LIS
-
SCL
1 stop15h 00m
LATAM Airlines
Deal found 8/3£680
Tue 11/808:19
SCL
-
LIS
2 stops17h 51m
LATAM Airlines
Tue 1/906:35
LIS
-
SCL
2 stops25h 15m
LATAM Airlines
Deal found 8/3£682
Mon 2/1122:45
SCL
-
LIS
2 stops30h 25m
United Airlines
Mon 16/1111:55
LIS
-
SCL
2 stops23h 55m
United Airlines
Deal found 8/3£686
Thu 1/1007:20
SCL
-
LIS
1 stop19h 50m
Multiple Airlines
Mon 12/1022:00
LIS
-
SCL
2 stops40h 30m
Multiple Airlines
Deal found 10/3£736
Thu 1/1016:58
SCL
-
LIS
2 stops58h 12m
LATAM Airlines
Mon 12/1009:50
LIS
-
SCL
1 stop17h 40m
LATAM Airlines
Deal found 10/3£765
Sun 22/301:40
SCL
-
LIS
2 stops34h 15m
Multiple Airlines
Sun 5/406:35
LIS
-
SCL
1 stop18h 45m
Multiple Airlines
Deal found 8/3£782
Mon 20/420:45
SCL
-
LIS
1 stop29h 25m
LATAM Airlines
Sun 17/509:40
LIS
-
SCL
1 stop34h 45m
LATAM Airlines
Deal found 6/3£785

Find flight deals from Santiago to Lisbon

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Lisbon (LIS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 March 2026.

Round-trip from

£650

One-way from

£436

Popular in

July

Cheapest in

November

Average price

£627
11/8-1/9
  • 11/8-1/9
  • 2 total stops
  • 51h 40m total
  • Santiago to Lisbon
24/3
  • 24/3
  • 3 total stops
  • 35h 29m total
  • Santiago to Lisbon
Highest demand for flights based on searches. 11% potential increase in price (£72 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£13 potential savings vs. average return price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 March 2026.
Use the filters below to find and compare flights from Santiago to Lisbon that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 22/3

01:40-14:55

2 stops34h 15m

Lisbon Humberto Delgado

Sun 5/4

06:35-20:20

1 stop18h 45m

£782

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 22/3

01:40-14:55

2 stops34h 15m

Lisbon Humberto Delgado

Fri 3/4

08:25-21:40

1 stop17h 15m

£787

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 22/3

01:40-21:55

2 stops41h 15m

Lisbon Humberto Delgado

Fri 3/4

18:55-08:25

2 stops41h 30m

£799

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Mon 18/5

07:20-23:10

2 stops34h 50m

Lisbon Humberto Delgado

Thu 18/6

16:30-07:30

1 stop20h 00m

£838

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 31/5

10:10-14:35

2 stops23h 25m

Lisbon Humberto Delgado

Mon 8/6

15:35-07:50

2 stops21h 15m

£858

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 22/3

01:40-21:55

2 stops41h 15m

Lisbon Humberto Delgado

Sun 5/4

18:50-07:25

2 stops41h 35m

£858

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sat 6/6

10:15-22:50

2 stops31h 35m

Lisbon Humberto Delgado

Sun 21/6

11:55-07:50

2 stops24h 55m

£916
Fastest return journey

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 31/5

10:10-14:35

2 stops23h 25m

Lisbon Humberto Delgado

Mon 8/6

18:50-07:50

1 stop18h 00m

£928

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 14/6

10:15-22:50

2 stops31h 35m

Lisbon Humberto Delgado

Tue 30/6

05:00-08:45

2 stops32h 45m

£1,044
Cheapest one-way

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 24/3

15:51-06:20

3 stops35h 29m

£436

Flights are sorted by cheapest return flights first.

Deals found on 10/3

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Lisbon

How far ahead should I book a flight from Santiago to Lisbon?

Use this chart to determine the optimal time to book a return flight from Santiago to Lisbon. Price data was last updated on 6 March 2026.

To ensure you get the cheapest price possible for a flight from Santiago to Lisbon, you should look to book at least 44 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santiago to Lisbon?

Currently, March is the cheapest month in which you can book a flight from Santiago to Lisbon (average of £486). Flying from Santiago to Lisbon in September is currently the most expensive (average of £664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Santiago to Lisbon?

    There are many flights that can get you from Santiago to Lisbon in 41h 15m. Fly via British Airways to get the fastest option. The distance between Santiago and Lisbon is about 6355 mi.

  • Can I find deals for flights from Santiago to Lisbon that include hotel bookings?

    Yes. In addition to deals on Santiago to Lisbon flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Lisbon.

  • Can I find deals for business class flights from Santiago to Lisbon?

    Yes. Cheapflights offers flight deals from Santiago to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Lisbon?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Lisbon (average of £486). Flying from Santiago to Lisbon in September is currently the most expensive (average of £664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Setúbal
Oeiras
Madeira
Fátima
Estoril
Óbidos
Almada
Beja
Sintra
Costa da Caparica
Nazaré
Sesimbra
Peniche

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