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Cheap flights from Santiago to Lisbon from £406

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/1. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — LIS
14 Nov — 21 Nov1
1 adult
1 adult, Economy

Find flight deals from Santiago to Lisbon

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Lisbon
Explore the most affordable flight options available from Santiago to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 October 2025.

Fri 28/1117:25SCL - LIS
1 stop14h 55mLATAM Airlines
Fri 5/1214:35LIS - SCL
1 stop24h 05mLATAM Airlines
Deal found 14/10£523
Thu 27/1122:45SCL - LIS
2 stops32h 30mUnited Airlines
Thu 4/1211:55LIS - SCL
2 stops47h 55mUnited Airlines
Deal found 13/10£622
Sat 1/1122:45SCL - LIS
2 stops32h 30mUnited Airlines
Thu 6/1111:55LIS - SCL
2 stops47h 55mUnited Airlines
Deal found 14/10£624
Thu 6/1112:30SCL - LIS
1 stop30h 25mBritish Airways
Sat 22/1107:00LIS - SCL
2 stops42h 15mBritish Airways
Deal found 15/10£703
Tue 4/1122:45SCL - LIS
2 stops56h 30mUnited Airlines
Wed 19/1110:15LIS - SCL
2 stops25h 35mUnited Airlines
Deal found 14/10£706
Tue 4/1113:05SCL - LIS
1 stop29h 40mBritish Airways
Sat 22/1111:05LIS - SCL
2 stops38h 10mBritish Airways
Deal found 14/10£708
Thu 6/1122:45SCL - LIS
2 stops55h 00mUnited Airlines
Tue 18/1111:55LIS - SCL
2 stops47h 55mUnited Airlines
Deal found 15/10£716
Sun 2/1122:45SCL - LIS
2 stops57h 15mUnited Airlines
Wed 19/1110:15LIS - SCL
2 stops25h 35mUnited Airlines
Deal found 14/10£721

Cheap flight deals from Santiago to Lisbon

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Lisbon (LIS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 October 2025.

Round-trip from

£523

One-way from

£406

Popular in

July

Cheapest in

November

Average price

£650
LATAM Airlines
  • LATAM Airlines
  • 28/11-5/12
  • 2 total stops
  • 39h 00m total
  • Santiago to Lisbon
Search Deals
United Airlines
  • United Airlines
  • 27/1
  • 2 total stops
  • 30h 25m total
  • Santiago to Lisbon
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£62 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£11 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customise your flight search to find flights from Santiago to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 October 2025.
Use the filters below to find and compare flights from Santiago to Lisbon that are best for you.

Fly from

Santiago

Fly to

Lisbon

Route

Depart

Return

Price

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sat 1/11

22:45-10:15

2 stops32h 30m

Lisbon Humberto Delgado

Thu 6/11

11:55-08:50

2 stops47h 55m

£624

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 17/3

21:45-13:20

2 stops36h 35m

Lisbon Humberto Delgado

Mon 23/3

11:55-07:50

2 stops46h 55m

£645

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 17/3

21:45-13:20

2 stops36h 35m

Lisbon Humberto Delgado

Wed 25/3

11:55-07:50

2 stops46h 55m

£645

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Mon 16/3

21:45-08:45

2 stops56h 00m

Lisbon Humberto Delgado

Wed 25/3

11:55-07:50

2 stops46h 55m

£681

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 6/11

12:30-21:55

1 stop30h 25m

Lisbon Humberto Delgado

Sat 22/11

07:00-22:15

2 stops42h 15m

£703

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 6/11

22:45-08:45

2 stops55h 00m

Lisbon Humberto Delgado

Wed 19/11

10:15-08:50

2 stops25h 35m

£716

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 28/10

21:45-10:15

2 stops33h 30m

Lisbon Humberto Delgado

Fri 14/11

11:55-08:50

2 stops47h 55m

£747

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 5/3

01:35-12:05

2 stops31h 30m

Lisbon Humberto Delgado

Fri 13/3

08:20-22:15

1 stop16h 55m

£762

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Wed 5/11

23:55-10:05

2 stops55h 10m

Lisbon Humberto Delgado

Sat 22/11

07:00-22:15

2 stops42h 15m

£765

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 6/11

12:30-21:55

1 stop30h 25m

Lisbon Humberto Delgado

Fri 21/11

18:45-22:15

2 stops54h 30m

£768

Flights are sorted by cheapest return flights first.

Deals found on 13/10

Showing 1-10 of 20 results
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Best time to book a flight from Santiago to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from Santiago with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Lisbon

How far ahead should I book a flight from Santiago to Lisbon?

Use this chart to determine the optimal time to book a return flight from Santiago to Lisbon. Price data was last updated on 10 October 2025.

To ensure you get the cheapest price possible for a flight from Santiago to Lisbon, you should look to book at least 58 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santiago to Lisbon?

Currently, March is the cheapest month in which you can book a flight from Santiago to Lisbon (average of £497). Flying from Santiago to Lisbon in September is currently the most expensive (average of £685). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Santiago to Lisbon?

Related info for your journey

Find useful and relevant information for your journey from Santiago to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Lisbon?

    There are many flights that can get you from Santiago to Lisbon in 19h 45m. Fly via United Airlines or Iberia to get the fastest option. The distance between Santiago and Lisbon is about 6355 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santiago to Lisbon that include hotel bookings?

    Yes. In addition to deals on Santiago to Lisbon flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Lisbon.

  • Can I find deals for business class flights from Santiago to Lisbon?

    Yes. Cheapflights offers flight deals from Santiago to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Lisbon?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Lisbon (average of £497). Flying from Santiago to Lisbon in September is currently the most expensive (average of £685). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Madeira
Setúbal
Oeiras
Fátima
Almada
Estoril
Beja
Sintra
Costa da Caparica
Óbidos
Nazaré
Sesimbra
Peniche

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