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Cheap flights from Des Moines to Manchester from £467

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAN
27 Feb — 6 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Des Moines to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Des Moines to Manchester
Explore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 January 2026.

Thu 26/208:00
DSM
-
MAN
2 stops20h 20m
United Airlines
Mon 2/306:10
MAN
-
DSM
2 stops34h 43m
United Airlines
Deal found 25/1£467
Wed 25/208:00
DSM
-
MAN
2 stops20h 20m
United Airlines
Sun 1/306:00
MAN
-
DSM
2 stops34h 53m
United Airlines
Deal found 25/1£475
Tue 10/318:49
DSM
-
MAN
2 stops34h 31m
United Airlines
Tue 17/306:00
MAN
-
DSM
3 stops39h 07m
United Airlines
Deal found 25/1£483
Wed 11/311:26
DSM
-
MAN
2 stops16h 14m
United Airlines
Wed 18/306:00
MAN
-
DSM
3 stops39h 07m
United Airlines
Deal found 26/1£491
Thu 5/311:26
DSM
-
MAN
2 stops15h 19m
United Airlines
Mon 9/313:00
MAN
-
DSM
2 stops36h 27m
United Airlines
Deal found 26/1£535
Fri 13/210:57
DSM
-
MAN
2 stops19h 48m
Delta
Sat 21/213:30
MAN
-
DSM
2 stops26h 47m
Delta
Deal found 27/1£612
Fri 13/213:38
DSM
-
MAN
2 stops24h 27m
British Airways
Sat 21/215:10
MAN
-
DSM
2 stops38h 30m
British Airways
Deal found 26/1£615
Thu 19/215:24
DSM
-
MAN
2 stops12h 56m
United Airlines
Mon 23/213:00
MAN
-
DSM
2 stops37h 07m
United Airlines
Deal found 27/1£637
Fri 30/111:30
DSM
-
MAN
2 stops16h 50m
United Airlines
Tue 3/206:10
MAN
-
DSM
2 stops21h 40m
United Airlines
Deal found 26/1£645

Find flight deals from Des Moines to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 January 2026.

Round-trip from

£467

Popular in

June

Cheapest in

September
United Airlines
  • United Airlines
  • 26/2-2/3
  • 4 total stops
  • 55h 03m total
  • Des Moines to Manchester
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (£84 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£21 potential savings vs. average return price).
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 January 2026.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.

Fly from

Des Moines

Fly to

Manchester

Route

Depart

Return

Price

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 10/3

15:28-10:20

2 stops13h 52m

Manchester

Tue 17/3

06:10-18:08

2 stops16h 58m

£467

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Thu 26/2

08:00-10:20

2 stops20h 20m

Manchester

Mon 2/3

06:10-10:53

2 stops34h 43m

£467

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Thu 5/3

08:00-08:45

2 stops18h 45m

Manchester

Mon 9/3

06:10-13:23

2 stops36h 13m

£475

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 11/3

08:00-08:40

2 stops19h 40m

Manchester

Wed 18/3

06:10-14:24

2 stops37h 14m

£475

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 4/3

08:00-10:20

2 stops20h 20m

Manchester

Sun 8/3

06:00-20:40

2 stops20h 40m

£475

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 13/2

10:57-12:45

2 stops19h 48m

Manchester

Sat 21/2

13:30-10:17

2 stops26h 47m

£612

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 13/3

19:44-11:45

2 stops35h 01m

£523

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Thu 12/3

11:26-10:20

2 stops17h 54m

£660

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 13/3

08:00-10:20

2 stops21h 20m

£666

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 13/3

08:00-10:20

3 stops21h 20m

£1,013

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 11 results
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Best time to book a flight from Des Moines to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Manchester?

    Airlines like United Airlines fly from Des Moines to Manchester in about 13h 52m. The time it takes to get you to your destination can typically vary by up to . The distance between Des Moines and Manchester is about 4045 mi.

  • Can I find deals for flights from Des Moines to Manchester that include hotel bookings?

    Yes. In addition to deals on Des Moines to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Manchester.

  • Can I find deals for business class flights from Des Moines to Manchester?

    Yes. Cheapflights offers flight deals from Des Moines to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Bradford
Lincoln
Derby
Harrogate
Stoke-on-Trent
Otley
Southport
Telford
Lancaster
Wakefield
Bolton
Preston
Salford
Huddersfield
Stockport
Rochdale
Blackburn
Skipton

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How does Cheapflights help users find flights from Des Moines to Manchester?

Cheapflights helps you search for flights from Des Moines to Manchester via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines to Manchester?

Cheapflights simply makes it quick and affordable to book flights from Des Moines to Manchester by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Des Moines to Manchester with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Des Moines to Manchester, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Des Moines to Manchester become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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