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Cheap flights from Des Moines to Manchester from £518

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAN
17 Apr — 24 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Des Moines to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Des Moines to Manchester
Explore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 March 2026.

Tue 1/1205:00
DSM
-
MAN
2 stops29h 55m
United Airlines
Thu 3/1211:50
MAN
-
DSM
2 stops41h 49m
United Airlines
Deal found 15/3£518
Sat 5/1218:45
DSM
-
MAN
2 stops40h 15m
United Airlines
Tue 8/1211:50
MAN
-
DSM
2 stops39h 27m
United Airlines
Deal found 15/3£523
Mon 7/1206:15
DSM
-
MAN
3 stops20h 45m
United Airlines
Wed 9/1206:10
MAN
-
DSM
2 stops19h 15m
United Airlines
Deal found 15/3£530
Sun 6/1220:15
DSM
-
MAN
2 stops30h 45m
United Airlines
Wed 9/1206:10
MAN
-
DSM
2 stops21h 07m
United Airlines
Deal found 13/3£530
Sat 5/1217:03
DSM
-
MAN
2 stops57h 57m
United Airlines
Wed 9/1206:10
MAN
-
DSM
2 stops21h 07m
United Airlines
Deal found 15/3£534
Tue 1/1217:03
DSM
-
MAN
2 stops39h 47m
United Airlines
Fri 4/1209:30
MAN
-
DSM
2 stops19h 31m
United Airlines
Deal found 15/3£549
Mon 7/1218:45
DSM
-
MAN
2 stops38h 05m
United Airlines
Thu 10/1211:50
MAN
-
DSM
2 stops28h 30m
United Airlines
Deal found 15/3£560

Find flight deals from Des Moines to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 March 2026.

Round-trip from

£619
United Airlines
  • United Airlines
  • 6/9-10/9
  • 4 total stops
  • 70h 02m total
  • Des Moines to Manchester
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 March 2026.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Sun 6/9

20:30-06:30

2 stops52h 00m

Manchester

Thu 10/9

06:05-18:07

2 stops18h 02m

£619

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 13/4

14:16-13:10

2 stops16h 54m

Manchester

Mon 20/4

20:15-19:33

2 stops29h 18m

£665

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 29/4

06:20-10:10

2 stops21h 50m

Manchester

Wed 6/5

06:05-18:05

2 stops18h 00m

£668

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 13/4

08:04-17:10

3 stops27h 06m

Manchester

Mon 20/4

10:35-22:43

2 stops42h 08m

£705

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 28/4

11:51-08:50

1 stop14h 59m

Manchester

Tue 5/5

13:00-17:45

1 stop34h 45m

£707
Fastest return journey

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 29/4

14:44-14:00

2 stops17h 16m

Manchester

Wed 6/5

10:40-17:45

1 stop13h 05m

£734

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 1/5

05:00-10:25

2 stops23h 25m

Manchester

Fri 8/5

06:05-21:23

2 stops21h 18m

£739

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 27/4

14:44-08:50

1 stop12h 06m

Manchester

Mon 4/5

05:55-21:12

2 stops21h 17m

£767

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 7/4

06:20-10:25

3 stops22h 05m

Manchester

Wed 15/4

06:05-21:32

3 stops21h 27m

£782

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 27/4

08:04-10:25

3 stops20h 21m

Manchester

Mon 4/5

06:05-18:05

3 stops18h 00m

£818

Flights are sorted by cheapest return flights first.

Deals found on 12/3

Sorted by cheapest first

Best time to book a flight from Des Moines to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Manchester?

    Airlines like United Airlines, British Airways, and Virgin Atlantic fly from Des Moines to Manchester in about 14h 59m. The time it takes to get you to your destination can typically vary by up to 37h 01m. The distance between Des Moines and Manchester is about 4045 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Manchester that include hotel bookings?

    Yes. In addition to deals on Des Moines to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Manchester.

  • Can I find deals for business class flights from Des Moines to Manchester?

    Yes. Cheapflights offers flight deals from Des Moines to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Stoke-on-Trent
Southport
Otley
Salford
Lancaster
Telford
Warrington
Huddersfield
Bolton
Preston
Wakefield
Macclesfield
Stockport
Wilmslow

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How does Cheapflights help users find flights from Des Moines to Manchester?

Cheapflights helps you search for flights from Des Moines to Manchester via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines to Manchester?

Cheapflights simply makes it quick and affordable to book flights from Des Moines to Manchester by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Des Moines to Manchester with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Des Moines to Manchester, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Des Moines to Manchester become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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