Find flights
When to book
FAQs

Cheap flights from Des Moines to Manchester from £332

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAN
8 Sep — 15 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Des Moines to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Des Moines to Manchester
Explore the most affordable flight options available from Des Moines to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 August 2026.

Sun 15/1118:45 -
2 stops31h 55m
Wed 18/1106:10 -
2 stops19h 06m
Deal found 6/8£597
Wed 23/906:00 -
2 stops19h 15m
Wed 30/914:55 -
2 stops25h 51m
Deal found 8/8£730
Mon 21/917:56 -
2 stops15h 14m
Mon 28/920:15 -
2 stops29h 06m
Deal found 7/8£733
Sun 6/905:40 -
1 stop19h 35m
Sun 13/920:45 -
2 stops26h 34m
Deal found 6/8£750
Sun 20/917:57 -
2 stops16h 08m
Sun 27/910:35 -
2 stops14h 46m
Deal found 5/8£762
Sun 20/910:20 -
2 stops24h 35m
Sun 27/911:15 -
1 stop17h 11m
Deal found 6/8£765
Sun 20/914:44 -
2 stops19h 21m
Sun 27/907:00 -
2 stops18h 21m
Deal found 6/8£766
Sun 6/911:00 -
2 stops17h 00m
Sun 13/911:15 -
1 stop17h 11m
Deal found 5/8£767
Sun 20/917:59 -
2 stops14h 01m
Sun 27/911:15 -
1 stop17h 11m
Deal found 5/8£768
Sat 19/916:20 -
2 stops34h 05m
Sat 26/917:30 -
2 stops33h 41m
Deal found 5/8£769
Sun 20/905:45 -
1 stop19h 30m
Sun 27/905:55 -
2 stops21h 16m
Deal found 6/8£770

Find flight deals from Des Moines to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 9 August 2026.

Round-trip from

£597

One-way from

£336
United Airlines
  • United Airlines
  • 15/11-18/11
  • 4 total stops
  • 51h 01m total
  • Des Moines to Manchester
Search Deals
British Airways
  • British Airways
  • 21/9
  • 2 total stops
  • 16h 41m total
  • Des Moines to Manchester
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 August 2026.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Sun 15/11

18:45-08:40

2 stops31h 55m

Manchester

Wed 18/11

06:10-19:16

2 stops19h 06m

£597

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Wed 23/9

06:00-07:15

2 stops19h 15m

Manchester

Wed 30/9

14:55-10:46

2 stops25h 51m

£730
Fastest return journey

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Sun 20/9

17:57-16:05

2 stops16h 08m

Manchester

Sun 27/9

10:35-19:21

2 stops14h 46m

£762

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Sun 20/9

05:45-07:15

1 stop19h 30m

Manchester

Sun 27/9

05:55-21:11

2 stops21h 16m

£770

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Sun 6/9

12:30-10:10

2 stops15h 40m

Manchester

Sun 13/9

05:55-17:19

2 stops17h 24m

£771

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Mon 21/9

14:46-14:00

2 stops17h 14m

Manchester

Mon 28/9

13:00-10:46

1 stop27h 46m

£771

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Mon 21/9

15:22-06:30

2 stops33h 08m

Manchester

Mon 28/9

06:05-21:23

3 stops21h 18m

£774

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Wed 23/9

15:22-06:30

2 stops33h 08m

Manchester

Wed 30/9

09:00-21:27

3 stops18h 27m

£816

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Wed 23/9

18:54-08:50

1 stop31h 56m

Manchester

Wed 30/9

10:40-18:09

1 stop13h 29m

£848
Cheapest one-way

Des MoinesManchester

DSM Des Moines - MAN Manchester

DSMMAN

Des Moines

Wed 23/9

13:09-09:50

2 stops14h 41m

£332

Flights are sorted by cheapest return flights first.

Deals found on 9/8

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Des Moines to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Des Moines with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Manchester?

    Airlines like United Airlines, Delta, and American Airlines fly from Des Moines to Manchester in about 16h 08m. The time it takes to get you to your destination can typically vary by up to 15h 47m. The distance between Des Moines and Manchester is about 4045 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Manchester that include hotel bookings?

    Yes. In addition to deals on Des Moines to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Manchester.

  • Can I find deals for business class flights from Des Moines to Manchester?

    Yes. Cheapflights offers flight deals from Des Moines to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Bradford
Llandudno
Windermere
Southport
Lincoln
Derby
Harrogate
Stoke-on-Trent
Salford
Telford
Shrewsbury
Warrington
Otley
Wakefield
Burnley
Preston
Lancaster
Wilmslow
Macclesfield
Huddersfield

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Des Moines to Manchester?

Cheapflights helps you search for flights from Des Moines to Manchester via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Des Moines to Manchester?

Cheapflights simply makes it quick and affordable to book flights from Des Moines to Manchester by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Des Moines to Manchester with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Des Moines to Manchester, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Des Moines to Manchester become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.