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Cheap flights from Missouri to Manchester from £229

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
3 Sep — 10 Sep1
1 adult

Cheap flight deals from Missouri to Manchester

Keep the following information in mind while searching for Missouri to Manchester flight deals. Data was last updated 29 August 2025.

Round-trip from

£514

One-way from

£229

Popular in

June

Cheapest in

February

Average price

£538
Delta
  • Delta
  • 23/9-2/10
  • 2 total stops
  • 27h 48m total
  • Missouri to Manchester
Search Deals
15/12
  • 15/12
  • 3 total stops
  • 40h 26m total
  • Missouri to Manchester
Search Deals
Highest demand for flights based on searches. 27% potential increase in price (£184 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£26 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2025
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Find flight deals from Missouri to Manchester

Cheapest flights from Missouri to Manchester
Explore the most affordable flight options available from Missouri to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 August 2025.

Tue 23/915:36STL - MAN
1 stop10h 59mDelta
Thu 2/1012:35MAN - STL
1 stop16h 49mDelta
Deal found 28/8£514
Tue 23/917:25STL - MAN
2 stops15h 50mAmerican Airlines
Thu 2/1008:10MAN - STL
2 stops18h 15mAmerican Airlines
Deal found 28/8£524
Wed 24/909:15STL - MAN
1 stop19h 05mMultiple Airlines
Wed 1/1013:15MAN - STL
2 stops40h 29mMultiple Airlines
Deal found 27/8£548
Mon 15/1209:59MCI - MAN
1 stop14h 41mMultiple Airlines
Thu 15/113:30MAN - MCI
1 stop13h 38mMultiple Airlines
Deal found 28/8£548
Sun 12/1013:30STL - MAN
1 stop13h 05mVirgin Atlantic
Sun 19/1012:35MAN - STL
1 stop17h 06mVirgin Atlantic
Deal found 28/8£551
Sun 12/1012:37MCI - MAN
1 stop13h 58mVirgin Atlantic
Sun 19/1012:35MAN - MCI
1 stop15h 52mVirgin Atlantic
Deal found 28/8£551
Fri 5/1214:41MCI - MAN
2 stops17h 39mAmerican Airlines
Tue 9/1208:05MAN - MCI
2 stops19h 20mAmerican Airlines
Deal found 28/8£552
Sun 12/1006:40STL - MAN
2 stops18h 55mDelta
Sun 19/1012:35MAN - STL
1 stop15h 01mDelta
Deal found 28/8£554
Fri 5/1214:55MCI - MAN
1 stop13h 35mVirgin Atlantic
Tue 9/1213:30MAN - MCI
1 stop16h 27mVirgin Atlantic
Deal found 28/8£558
Wed 24/907:08STL - MAN
2 stops21h 12mUnited Airlines
Wed 1/1006:05MAN - STL
2 stops33h 57mUnited Airlines
Deal found 27/8£559
Mon 22/916:32STL - MAN
2 stops59h 48mUnited Airlines
Sat 27/911:50MAN - STL
2 stops40h 10mUnited Airlines
Deal found 27/8£563
Fri 26/911:04STL - MAN
1 stop15h 31mVirgin Atlantic
Fri 3/1012:35MAN - STL
1 stop14h 40mVirgin Atlantic
Deal found 27/8£566

Cheapflights Fare Finder

 
Customise your flight search to find flights from Missouri to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 August 2025.
Use the filters below to find and compare flights from Missouri to Manchester that are best for you.

Fly from

Missouri

Fly to

Manchester

Route

Depart

Return

Price

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 23/9

15:36-08:35

1 stop10h 59m

Manchester

Thu 2/10

12:35-23:24

1 stop16h 49m

£514

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 23/9

17:25-15:15

2 stops15h 50m

Manchester

Thu 2/10

08:10-20:25

2 stops18h 15m

£524

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Wed 7/1

18:09-13:55

2 stops13h 46m

Manchester

Mon 12/1

20:05-19:12

2 stops29h 07m

£531

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sat 18/10

20:00-21:35

2 stops43h 35m

Manchester

Wed 22/10

08:00-20:14

2 stops18h 14m

£544

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Wed 24/9

09:15-10:20

1 stop19h 05m

Manchester

Wed 1/10

13:15-23:44

2 stops40h 29m

£548

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Mon 15/12

09:59-06:40

1 stop14h 41m

Manchester

Thu 15/1

13:30-21:08

1 stop13h 38m

£548

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Mon 15/12

14:38-14:00

2 stops17h 22m

Manchester

Thu 15/1

07:45-22:25

2 stops20h 40m

£548

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sun 12/10

13:30-08:35

1 stop13h 05m

Manchester

Sun 19/10

12:35-23:41

1 stop17h 06m

£551

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Sun 12/10

12:37-08:35

1 stop13h 58m

Manchester

Sun 19/10

12:35-22:27

1 stop15h 52m

£551

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Fri 5/12

14:41-14:20

2 stops17h 39m

Manchester

Tue 9/12

08:05-21:25

2 stops19h 20m

£552

Flights are sorted by cheapest return flights first.

Deals found on 28/8

Showing 1-10 of 29 results
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Best time to book a flight from Missouri to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Manchester

What is the cheapest month to book a flight from Missouri to Manchester?

Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of £117). Flying from Missouri to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MAN?

Find hourly flight availability from Missouri to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 29 August 2025.

When flying from Missouri to Manchester, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Missouri?

    For a flight from Missouri to Manchester, you will be flying into Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Missouri to Manchester?

    A quick flight from Missouri to Manchester can take about 10h 59m. Delta provides one of the quickest options available for as low as £514. The distance between Missouri and Manchester is about 4061 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Manchester one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as £347. However, be on the lookout for offers from Virgin Atlantic and Delta, as they are both options that can get you from Missouri to Manchester for a low price.

  • What are the most popular routes from Missouri to Manchester?

    While some choose either Lambert-St Louis - Manchester or Springfield-Branson - Manchester, Kansas City - Manchester is the most popular route from Missouri to Manchester.

  • Can I find deals for flights from Missouri to Manchester that include hotel bookings?

    Yes. In addition to deals on Missouri to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Manchester.

  • Can I find deals for business class flights from Missouri to Manchester?

    Yes. Cheapflights offers flight deals from Missouri to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of £117). Flying from Missouri to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Top airline flying from Missouri to Manchester

Discover the top airline that operate flights from Missouri to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 August 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£441Average£594FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri to Manchester?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Manchester from Missouri today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Missouri to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from Missouri.

Can Cheapflights find flights from Missouri to Manchester with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Missouri to Manchester flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Missouri to Manchester become cheaper?

Yes! Start tracking prices for Missouri to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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