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Cheap flights from Missouri to Manchester from £254

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
15 Oct — 22 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Missouri to Manchester

Keep the following information in mind while searching for Missouri to Manchester flight deals. Data was last updated 15 September 2025.

Round-trip from

£458

One-way from

£254

Popular in

June

Cheapest in

February

Average price

£565
Virgin Atlantic
  • Virgin Atlantic
  • 29/10-5/11
  • 2 total stops
  • 33h 03m total
  • Missouri to Manchester
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14/10
  • 14/10
  • 3 total stops
  • 44h 10m total
  • Missouri to Manchester
Search Deals
Highest demand for flights based on searches. 27% potential increase in price (£183 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Missouri to Manchester

Cheapest flights from Missouri to Manchester
Explore the most affordable flight options available from Missouri to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Wed 29/1012:36MCI - MAN
1 stop16h 54mVirgin Atlantic
Wed 5/1113:30MAN - MCI
1 stop16h 09mVirgin Atlantic
Deal found 14/9£458
Wed 29/1018:18MCI - MAN
2 stops17h 02mBritish Airways
Wed 5/1112:10MAN - MCI
2 stops16h 57mBritish Airways
Deal found 14/9£484
Tue 14/1009:50MCI - MAN
1 stop15h 45mDelta
Tue 21/1012:35MAN - MCI
1 stop17h 17mDelta
Deal found 14/9£491
Tue 28/1017:15STL - MAN
2 stops17h 50mDelta
Tue 4/1113:30MAN - STL
1 stop14h 34mDelta
Deal found 13/9£498
Tue 28/1016:33STL - MAN
2 stops16h 27mAmerican Airlines
Tue 4/1108:55MAN - STL
2 stops15h 30mAmerican Airlines
Deal found 13/9£499
Wed 29/1016:05SGF - MAN
2 stops13h 50mAmerican Airlines
Wed 5/1107:50MAN - SGF
2 stops18h 57mAmerican Airlines
Deal found 13/9£499
Mon 15/1215:39MCI - MAN
2 stops16h 21mBritish Airways
Thu 15/109:45MAN - MCI
2 stops18h 40mBritish Airways
Deal found 13/9£506
Tue 14/1015:28MCI - MAN
2 stops15h 42mAmerican Airlines
Tue 21/1007:00MAN - MCI
2 stops19h 52mAmerican Airlines
Deal found 14/9£507
Sun 9/1116:42STL - MAN
2 stops15h 18mAmerican Airlines
Fri 14/1108:05MAN - STL
2 stops17h 25mAmerican Airlines
Deal found 14/9£514
Wed 29/1011:05STL - MAN
2 stops16h 35mUnited Airlines
Wed 5/1106:00MAN - STL
1 stop13h 55mUnited Airlines
Deal found 14/9£515
Wed 29/1015:35SGF - MAN
2 stops23h 30mDelta
Wed 5/1113:30MAN - SGF
1 stop14h 39mDelta
Deal found 13/9£516
Sun 9/1119:02STL - MAN
2 stops15h 03mDelta
Fri 14/1113:25MAN - STL
1 stop16h 15mDelta
Deal found 14/9£520

Cheapflights Fare Finder

 
Customise your flight search to find flights from Missouri to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 September 2025.
Use the filters below to find and compare flights from Missouri to Manchester that are best for you.

Fly from

Missouri

Fly to

Manchester

Route

Depart

Return

Price

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Tue 14/10

09:50-07:35

1 stop15h 45m

Manchester

Tue 21/10

12:35-23:52

1 stop17h 17m

£491

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 28/10

17:15-16:05

2 stops17h 50m

Manchester

Tue 4/11

13:30-22:04

1 stop14h 34m

£498

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 28/10

16:33-14:00

2 stops16h 27m

Manchester

Tue 4/11

08:55-18:25

2 stops15h 30m

£499

SpringfieldManchester

SGF - MAN

SGFMAN

Springfield-Branson

Wed 29/10

16:05-10:55

2 stops13h 50m

Manchester

Wed 5/11

07:50-20:47

2 stops18h 57m

£499

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Tue 14/10

15:28-13:10

2 stops15h 42m

Manchester

Tue 21/10

07:00-20:52

2 stops19h 52m

£507

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sun 9/11

16:42-14:00

2 stops15h 18m

Manchester

Fri 14/11

08:05-19:30

2 stops17h 25m

£514

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Wed 29/10

11:05-08:40

2 stops16h 35m

Manchester

Wed 5/11

06:00-13:55

1 stop13h 55m

£515

SpringfieldManchester

SGF - MAN

SGFMAN

Springfield-Branson

Wed 29/10

15:35-20:05

2 stops23h 30m

Manchester

Wed 5/11

13:30-22:09

1 stop14h 39m

£516

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sun 9/11

19:02-16:05

2 stops15h 03m

Manchester

Fri 14/11

13:25-23:40

1 stop16h 15m

£520

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 28/10

17:24-17:00

2 stops18h 36m

Manchester

Tue 4/11

09:25-21:54

2 stops18h 29m

£522

Flights are sorted by cheapest return flights first.

Deals found on 14/9

Showing 1-10 of 28 results
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Best time to book a flight from Missouri to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Manchester

What is the cheapest month to book a flight from Missouri to Manchester?

Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of £117). Flying from Missouri to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MAN?

Find hourly flight availability from Missouri to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 September 2025.

When flying from Missouri to Manchester, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Missouri to Manchester?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Missouri?

    For a flight from Missouri to Manchester, you will be flying into Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Missouri to Manchester?

    A quick flight from Missouri to Manchester can take about 15h 45m. Delta provides one of the quickest options available for as low as £491. The distance between Missouri and Manchester is about 4195 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Manchester one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as £309. However, be on the lookout for offers from Virgin Atlantic and Delta, as they are both options that can get you from Missouri to Manchester for a low price.

  • What are the most popular routes from Missouri to Manchester?

    While some choose either Kansas City - Manchester or Springfield-Branson - Manchester, Lambert-St Louis - Manchester is the most popular route from Missouri to Manchester.

  • Can I find deals for flights from Missouri to Manchester that include hotel bookings?

    Yes. In addition to deals on Missouri to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Manchester.

  • Can I find deals for business class flights from Missouri to Manchester?

    Yes. Cheapflights offers flight deals from Missouri to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of £117). Flying from Missouri to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Derby
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Bradford
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Stoke-on-Trent
Stockport
Wakefield
Southport
Morecambe
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Salford
Rochdale
Huddersfield
Wigan

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Top airline flying from Missouri to Manchester

Discover the top airline that operate flights from Missouri to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 September 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£439Average£588FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Missouri to Manchester?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Manchester from Missouri today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Missouri to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from Missouri.

Can Cheapflights find flights from Missouri to Manchester with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Missouri to Manchester flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Missouri to Manchester become cheaper?

Yes! Start tracking prices for Missouri to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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