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Cheap flights from Missouri to Manchester from £243

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
24 Jan — 31 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Missouri to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Missouri to Manchester
Explore the most affordable flight options available from Missouri to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 December 2025.

Fri 26/1218:36MCI - MAN
2 stops15h 59mBritish Airways
Tue 6/117:30MAN - MCI
2 stops33h 36mBritish Airways
Deal found 23/12£752
Fri 26/1215:29MCI - MAN
2 stops15h 16mKLM
Tue 6/113:30MAN - MCI
1 stop15h 21mKLM
Deal found 25/12£1,041
Fri 26/1218:35STL - MAN
2 stops16h 00mBritish Airways
Fri 2/119:55MAN - STL
2 stops29h 31mBritish Airways
Deal found 23/12£1,177
Fri 26/1207:05MCI - MAN
1 stop21h 25mDelta
Tue 6/113:00MAN - MCI
2 stops27h 16mDelta
Deal found 24/12£1,255
Fri 26/1218:35STL - MAN
2 stops16h 20mLufthansa
Fri 2/106:05MAN - STL
1 stop13h 50mLufthansa
Deal found 23/12£1,260
Fri 26/1207:40MCI - MAN
3 stops20h 40mAir Canada
Tue 6/106:10MAN - MCI
3 stops17h 31mAir Canada
Deal found 24/12£1,604
Fri 26/1206:20STL - MAN
2 stops43h 35mMultiple Airlines
Fri 2/110:15MAN - STL
3 stops42h 41mMultiple Airlines
Deal found 23/12£9,338

Find flight deals from Missouri to Manchester

Keep the following information in mind while searching for Missouri to Manchester flight deals. Data was last updated 25 December 2025.

Round-trip from

£450

One-way from

£243

Popular in

June

Cheapest in

January

Average price

£579
Lufthansa
  • Lufthansa
  • 20/1-27/1
  • 4 total stops
  • 39h 34m total
  • Missouri to Manchester
Search Deals
Aer Lingus
  • Aer Lingus
  • 10/3
  • 2 total stops
  • 28h 43m total
  • Missouri to Manchester
Search Deals
Highest demand for flights based on searches. 24% potential increase in price (£169 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease (£33 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Missouri to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 25 December 2025.
Use the filters below to find and compare flights from Missouri to Manchester that are best for you.

Fly from

Missouri

Fly to

Manchester

Route

Depart

Return

Price

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Tue 20/1

18:30-23:20

2 stops22h 50m

Manchester

Tue 27/1

11:15-21:59

2 stops16h 44m

£450

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sat 7/2

13:40-11:45

2 stops16h 05m

Manchester

Sat 14/2

06:15-23:02

2 stops22h 47m

£455

SpringfieldManchester

SGF - MAN

SGFMAN

Springfield-Branson

Thu 5/2

16:29-19:05

2 stops20h 36m

Manchester

Thu 12/2

11:40-23:54

2 stops18h 14m

£455

SpringfieldManchester

SGF - MAN

SGFMAN

Springfield-Branson

Thu 5/2

17:00-10:30

1 stop11h 30m

Manchester

Thu 12/2

05:50-16:47

2 stops16h 57m

£468

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 5/5

22:00-19:05

1 stop15h 05m

Manchester

Tue 19/5

14:10-19:30

1 stop11h 20m

£468

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Sat 7/2

07:10-10:30

1 stop21h 20m

Manchester

Sat 14/2

09:05-20:43

2 stops17h 38m

£468

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 5/5

18:49-23:15

2 stops22h 26m

Manchester

Tue 19/5

07:00-21:04

2 stops20h 04m

£469

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Wed 4/2

18:30-10:20

2 stops33h 50m

Manchester

Sun 8/2

06:00-21:59

2 stops21h 59m

£482

SpringfieldManchester

SGF - MAN

SGFMAN

Springfield-Branson

Wed 4/2

07:50-10:20

2 stops20h 30m

Manchester

Sun 8/2

06:00-21:44

2 stops21h 44m

£482

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Fri 20/2

07:41-12:20

2 stops22h 39m

Manchester

Tue 24/2

06:10-20:23

2 stops20h 13m

£548

Flights are sorted by cheapest return flights first.

Deals found on 25/12

Showing 1-10 of 27 results
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Best time to book a flight from Missouri to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Manchester

What is the cheapest month to book a flight from Missouri to Manchester?

Currently, September is the cheapest month in which you can book a flight from Missouri to Manchester (average of £340). Flying from Missouri to Manchester in June is currently the most expensive (average of £568). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MAN?

Find hourly flight availability from Missouri to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 25 December 2025.

It’s optimal to fly from Missouri to Manchester in the morning. By choosing this option you can save up to 31% on the cost of your flight, compared to a flight at midday.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Missouri?

    For a flight from Missouri to Manchester, you will be flying into Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Missouri to Manchester?

    A quick flight from Missouri to Manchester can take about 11h 30m. Lufthansa provides one of the quickest options available for as low as £468. The distance between Missouri and Manchester is about 4250 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Manchester?

    While some choose either Springfield-Branson - Manchester or Kansas City - Manchester, Lambert-St Louis - Manchester is the most popular route from Missouri to Manchester.

  • Can I find deals for flights from Missouri to Manchester that include hotel bookings?

    Yes. In addition to deals on Missouri to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Manchester.

  • Can I find deals for business class flights from Missouri to Manchester?

    Yes. Cheapflights offers flight deals from Missouri to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Manchester?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Manchester (average of £340). Flying from Missouri to Manchester in June is currently the most expensive (average of £568). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Otley
Telford
Stoke-on-Trent
Southport
Lancaster
Morecambe
Preston
Wakefield
Salford
Bolton
Blackburn
Stockport
Huddersfield
Crewe

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Top airline flying from Missouri to Manchester

Discover the top airline that operate flights from Missouri to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 25 December 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£431Average£591FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Missouri to Manchester?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Manchester from Missouri today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Missouri to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from Missouri.

Can Cheapflights find flights from Missouri to Manchester with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Missouri to Manchester flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Missouri to Manchester become cheaper?

Yes! Start tracking prices for Missouri to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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