Cheap flights from Panama City to Mexico City from £158

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MEX
4 Aug — 11 Aug1
1 adult

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Mexico City Benito Juarez are usually found in July or June, booked 69 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Panama City to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 July 2025.

Round-trip from

£234

One-way from

£158

Popular in

October

Cheapest in

July

Average price

£262

Good round-trip deal

£254 or less
Avianca
  • Avianca
  • 17/9-24/9
  • 2 total stops
  • 31h 35m total
  • Panama City to Mexico City
Avianca
  • Avianca
  • 11/9
  • 1 total stop
  • 24h 45m total
  • Panama City to Mexico City
Highest demand for flights based on searches. 5% potential increase in price (£13 potential increase over avg. return price).
Cheapest flight prices on average. 0% potential price decrease (£2 potential savings vs. average return price).
Average for round-trip flights in July 2025
Price to beat on a round-trip flight from Panama City Tocumen Intl to Mexico City Benito Juarez.

Find flight deals from Panama City to Mexico City

Cheapest flights from Panama City to Mexico City
Explore the most affordable flight options available from Panama City to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 July 2025.

Wed 17/922:05PTY - MEX
1 stop21h 00mAvianca
Wed 24/904:55MEX - PTY
1 stop10h 35mAvianca
Deal found 28/7£234
Wed 10/914:44PTY - MEX
Nonstop3h 56mAeromexico
Wed 17/908:50MEX - PTY
Nonstop3h 49mAeromexico
Deal found 27/7£247
Wed 10/919:21PTY - MEX
Nonstop3h 44mCopa Airlines
Tue 16/901:40MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 27/7£253
Tue 9/903:20PTY - MEX
2 stops15h 25mMultiple Airlines
Wed 17/923:20MEX - PTY
1 stop8h 35mMultiple Airlines
Deal found 27/7£385

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 July 2025.
Use the filters below to find and compare flights from Panama City to Mexico City that are best for you.

Fly from

Panama City

Fly to

Mexico City

Route

Depart

Return

Price

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 17/9

22:05-18:05

1 stop21h 00m

Mexico City Benito Juarez

Wed 24/9

04:55-16:30

1 stop10h 35m

£234

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 10/9

14:44-17:40

Nonstop3h 56m

Mexico City Benito Juarez

Wed 17/9

08:50-13:39

Nonstop3h 49m

£247

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 10/9

19:21-22:05

Nonstop3h 44m

Mexico City Benito Juarez

Tue 16/9

01:40-06:20

Nonstop3h 40m

£253

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Tue 9/9

03:20-17:45

2 stops15h 25m

Mexico City Benito Juarez

Wed 17/9

23:20-08:55

1 stop8h 35m

£385

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 11/9

03:20-03:05

1 stop24h 45m

£158

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Mon 4/8

19:09-22:05

Nonstop3h 56m

£388

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Sun 21/9

09:22-08:35

3 stops24h 13m

£1,455

Flights are sorted by cheapest return flights first.

Deals found on 29/7

Best time to book a flight from Panama City to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City

How far ahead should I book a flight from Panama City to Mexico City?

Use this chart to determine the optimal time to book a return flight from Panama City to Mexico City. Price data was last updated on 25 July 2025.

The price you pay for your flight from Panama City to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Mexico City?

Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £791). Flying from Panama City to Mexico City in July is currently the most expensive (average of £1,261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MEX?

Find hourly flight availability from Panama City to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 July 2025.

It’s optimal to fly from Panama City to Mexico City in the morning. By choosing this option you can save up to 21% on the cost of your flight, compared to a flight at midday.

Weekly flight availability from Panama City to Mexico City

Explore weekly flight availability from Panama City to Mexico City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 30 July 2025.

The most flights from PTY to MEX are scheduled on a Tuesday (9 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost for a return flight from Panama City to Mexico City?

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated 30 July 2025.
Read reviews from past customers who have flown with Copa Airlines, Aeromexico, andUnited Airlines from Panama City to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.1

Overall

7.5

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Crew

8.1

Overall

7.5

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Crew

8.1

Overall

7.5

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Crew

8.1

Overall

7.5

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Crew

8.1

Overall

7.5

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Panama City to Mexico City?

    You will need to book a flight from Panama City Tocumen Intl to Mexico City Benito Juarez if you want to fly from Panama City to Mexico City. At least 1 airline has flights from Tocumen Intl (PTY) to Benito Juarez (MEX) on a regular basis. There are 5 flights to Mexico City from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to MEX to be around 3h 39m.

  • How popular is this Panama City to Mexico City flight route?

  • What are the cheapest airlines flying from Panama City to Mexico City round-trip?

    Flying on Avianca is currently your cheapest option to Mexico City, with prices starting at £234. Additional return tickets that might be worth considering are offered by Aeromexico and Copa Airlines, with the lowest prices starting at £247 and £253, respectively. You may be able to fly from Panama City to Mexico City for 26% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City to Mexico City one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at £158. Copa Airlines flights start at £388 while deals on United Airlines start at £1,455 one-way.

  • What are the most reliable airlines from Panama City to Mexico City?

    No one likes to see their flight delayed. When booking a flight from Panama City to Mexico City consider choosing Emirates (90%), Copa Airlines (89%) or Aeromexico (61%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama City to Mexico City?

    On average you can expect to pay £255 for a flight from Panama City to Mexico City. The cheapest flight overall is £225 while the most popular route, (Panama City Tocumen Intl - Mexico City Benito Juarez) is currently priced at £253.

  • Can I find deals for flights from Panama City to Mexico City that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.

  • Can I find deals for business class flights from Panama City to Mexico City?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Mexico City?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £791). Flying from Panama City to Mexico City in July is currently the most expensive (average of £1,261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Panama City to Mexico City

Discover the top airline that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 July 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest£254Average£301FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

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Can Cheapflights notify me if prices for flights from Panama City to Mexico City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Mexico City from Panama City today and book when prices fit your budget.

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