Cheap flights from Panama City to Mexico City from £206
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 30/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MEX
11 Jan — 18 Jan1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Panama City Tocumen Intl to Mexico City Benito Juarez are usually found in July or August, booked 75 days in advance, depart on a Monday or Tuesday and return on a Monday
Cheap flight deals from Panama City to Mexico City
Enter your travel dates to find the best prices.
Cheapest flights from Panama City to Mexico City
Explore the most affordable flight options available from Panama City to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 December 2025.
Tue 30/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Fri 9/115:30MEX - PTY
Nonstop3h 37mCopa Airlines
Deal found 10/12£206
Thu 25/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Sun 28/1205:55MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£247
Tue 23/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Mon 5/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£257
Tue 16/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Tue 23/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Deal found 12/12£273
Fri 19/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 22/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£289
Fri 12/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Sat 3/105:55MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 10/12£341
Wed 31/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Thu 1/115:30MEX - PTY
Nonstop3h 37mCopa Airlines
Deal found 9/12£379
Wed 17/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Mon 22/1205:55MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£419
Mon 22/1216:17PTY - MEX
Nonstop4h 03mCopa Airlines
Thu 25/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£445
Tue 16/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 22/1209:25MEX - PTY
Nonstop3h 49mCopa Airlines
Deal found 10/12£447
Sun 14/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Fri 19/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Deal found 11/12£473
Mon 29/1216:17PTY - MEX
Nonstop4h 03mCopa Airlines
Fri 2/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 9/12£494
Best flights from Panama City to Mexico City
Discover carefully curated flight deals from Panama City to Mexico City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 12 December 2025.
Tue 30/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Thu 1/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 11/12£206
Tue 30/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Sat 3/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 11/12£206
Wed 31/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Fri 2/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£206
Tue 30/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 12/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£206
Wed 24/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 29/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 11/12£206
Thu 25/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 29/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 11/12£206
Thu 25/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Fri 2/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£206
Tue 23/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Mon 5/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£257
Tue 23/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Wed 31/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 11/12£257
Sun 18/121:28PTY - MEX
Nonstop3h 47mCopa Airlines
Mon 16/209:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 11/12£262
Sat 7/218:57PTY - MEX
Nonstop4h 03mCopa Airlines
Sun 15/315:30MEX - PTY
Nonstop3h 43mCopa Airlines
Deal found 11/12£262
Sat 7/221:25PTY - MEX
Nonstop3h 50mCopa Airlines
Tue 17/205:55MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 9/12£262
Direct flights from Panama City to Mexico City
Explore direct flight options from Panama City to Mexico City based on user searches, and compare prices and availability for your desired travel dates. Data last updated 12 December 2025.
Tue 30/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Sat 10/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£206
Thu 1/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Sat 10/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£211
Thu 25/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Sun 28/1205:55MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£247
Tue 23/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Mon 5/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£257
Fri 16/121:28PTY - MEX
Nonstop3h 47mCopa Airlines
Fri 23/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£262
Fri 26/1221:28PTY - MEX
Nonstop3h 47mCopa Airlines
Mon 29/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£289
Wed 1/419:10PTY - MEX
Nonstop3h 55mCopa Airlines
Sun 5/405:50MEX - PTY
Nonstop3h 36mCopa Airlines
Deal found 10/12£294
Thu 1/109:21PTY - MEX
Nonstop3h 49mCopa Airlines
Tue 6/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£326
Mon 18/521:29PTY - MEX
Nonstop3h 46mCopa Airlines
Tue 2/605:50MEX - PTY
Nonstop3h 43mCopa Airlines
Deal found 10/12£330
Mon 18/511:45PTY - MEX
Nonstop3h 45mCopa Airlines
Sat 18/709:50MEX - PTY
Nonstop3h 46mCopa Airlines
Deal found 10/12£338
Sun 28/1209:03PTY - MEX
Nonstop3h 52mCopa Airlines
Sun 28/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£341
Sun 18/111:47PTY - MEX
Nonstop3h 43mCopa Airlines
Sat 18/709:50MEX - PTY
Nonstop3h 46mCopa Airlines
Deal found 10/12£344
Last-minute flights from Panama City to Mexico City
Discover last-minute flight deals from Panama City to Mexico City. Data last updated 12 December 2025 and is based on user searches.
Fri 12/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Sun 14/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 10/12£341
Tue 16/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Tue 23/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Deal found 12/12£273
Fri 19/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 22/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£289
Tue 23/1219:02PTY - MEX
Nonstop4h 03mCopa Airlines
Mon 5/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£257
Thu 25/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Sun 28/1205:55MEX - PTY
Nonstop3h 45mCopa Airlines
Deal found 10/12£247
Tue 30/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Mon 12/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£206
Thu 1/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Sat 10/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£211
Thu 1/118:58PTY - MEX
Nonstop4h 07mCopa Airlines
Fri 9/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£326
Tue 6/118:58PTY - MEX
Nonstop4h 07mCopa Airlines
Sun 25/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 10/12£352
Thu 8/121:28PTY - MEX
Nonstop3h 47mCopa Airlines
Sun 11/101:20MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 9/12£294
Fri 16/121:28PTY - MEX
Nonstop3h 47mCopa Airlines
Fri 23/113:10MEX - PTY
Nonstop3h 38mCopa Airlines
Deal found 10/12£262
Sun 18/111:47PTY - MEX
Nonstop3h 43mCopa Airlines
Sat 18/709:50MEX - PTY
Nonstop3h 46mCopa Airlines
Deal found 10/12£344
One-way flights from Panama City to Mexico City
Search for one-way flight options from Panama City to Mexico City. Find affordable one-way fares based on user searches. Data last updated 12 December 2025.
Wed 17/1221:28PTY - MEX
Nonstop3h 47mCopa Airlines
Deal found 10/12£388
Wed 7/116:13PTY - MEX
Nonstop4h 07mCopa Airlines
Deal found 12/12£393
Mon 5/109:21PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 10/12£417
Sun 4/116:41PTY - MEX
1 stop18h 24mUnited Airlines
Deal found 12/12£836
Find flight deals from Panama City to Mexico City
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 12 December 2025.
Customise your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 12 December 2025.
Use the filters below to find and compare flights from Panama City to Mexico City that are best for you.
Fly from
Panama City
Fly to
Mexico City
Route
Depart
Return
Price
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Tue 30/12
22:14-01:00
Nonstop3h 46m
Mexico City Benito Juarez
Thu 1/1
13:10-17:48
Nonstop3h 38m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Tue 30/12
22:14-01:00
Nonstop3h 46m
Mexico City Benito Juarez
Sat 3/1
09:25-14:06
Nonstop3h 41m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Wed 31/12
09:18-12:10
Nonstop3h 52m
Mexico City Benito Juarez
Fri 2/1
13:10-17:48
Nonstop3h 38m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Tue 30/12
09:18-12:10
Nonstop3h 52m
Mexico City Benito Juarez
Mon 12/1
09:25-14:06
Nonstop3h 41m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Wed 24/12
11:38-14:30
Nonstop3h 52m
Mexico City Benito Juarez
Mon 29/12
15:30-20:15
Nonstop3h 45m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Thu 25/12
09:18-12:10
Nonstop3h 52m
Mexico City Benito Juarez
Mon 29/12
15:30-20:15
Nonstop3h 45m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Thu 25/12
09:18-12:10
Nonstop3h 52m
Mexico City Benito Juarez
Fri 2/1
13:10-17:48
Nonstop3h 38m
£206
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Tue 23/12
19:02-22:05
Nonstop4h 03m
Mexico City Benito Juarez
Mon 5/1
13:10-17:48
Nonstop3h 38m
£257
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Tue 23/12
19:02-22:05
Nonstop4h 03m
Mexico City Benito Juarez
Wed 31/12
15:30-20:15
Nonstop3h 45m
£257
Panama CityMexico City
PTY - MEX
PTYMEX
Panama City Tocumen Intl
Sun 18/1
21:28-00:15
Nonstop3h 47m
Mexico City Benito Juarez
Mon 16/2
09:25-14:06
Nonstop3h 41m
£262
Flights are sorted by cheapest return flights first.
Deals found on 10/12
Showing 1-10 of 22 results
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Best time to book a flight from Panama City to Mexico City
Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Mexico City
Prices
Airlines
Delays
How far ahead should I book a flight from Panama City to Mexico City?
Use this chart to determine the optimal time to book a return flight from Panama City to Mexico City. Price data was last updated on 5 December 2025.
The price you pay for your flight from Panama City to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 75 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Panama City to Mexico City?
Currently, November is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £128). Flying from Panama City to Mexico City in March is currently the most expensive (average of £259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to MEX?
Find hourly flight availability from Panama City to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 12 December 2025.
It’s optimal to fly from Panama City to Mexico City in the afternoon. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight in the evening.
How much does it cost for a return flight from Panama City to Mexico City?
Weekly flight availability from Panama City to Mexico City
Explore weekly flight availability from Panama City to Mexico City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 12 December 2025.
The most flights from PTY to MEX are scheduled on a Wednesday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (6 on average).
How often are flights from Panama City to Mexico City delayed?
About 3% of weekly flights between Panama City and Mexico City have experienced delays in the past year, with the average delay time being 124 minutes.
What is the most punctual flight time for Panama City to Mexico City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Mexico City flights?
Over the past year, Copa Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.
Reviews of airlines servicing Mexico City
Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated 12 December 2025.
Read reviews from past customers who have flown with Copa Airlines
from Panama City to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Related info for your journey
Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Panama City to Mexico City?
You will need to book a flight from Panama City Tocumen Intl to Mexico City Benito Juarez if you want to fly from Panama City to Mexico City. At least 1 airline has flights from Tocumen Intl (PTY) to Benito Juarez (MEX) on a regular basis. There are 8 flights to Mexico City from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to MEX to be around 4h 07m.
How popular is this Panama City to Mexico City flight route?
The Panama City Tocumen Intl to Mexico City Benito Juarez flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Panama City to Mexico City?
For as low as £206, Copa Airlines can have you in Mexico City from Panama City in 3h 46m. Airlines will cover a distance of 1497 mi. All flights are typically direct.
What is the cheapest airline to fly from Panama City to Mexico City round-trip?
Flying on Copa Airlines is currently your cheapest option to Mexico City, with prices starting at £253. You may be able to fly from Panama City to Mexico City for 12% less than the average price by searching for this airline.
What are the most reliable airlines from Panama City to Mexico City?
No one likes to see their flight delayed. When booking a flight from Panama City to Mexico City consider choosing Copa Airlines (95%), AeroMexico Connect (92%) or Aeromexico (92%) as they are the most reliable in getting you off to your destination on time.
Can I find deals for flights from Panama City to Mexico City that include hotel bookings?
Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Panama City to Mexico City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.
Can I find deals for business class flights from Panama City to Mexico City?
Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to Mexico City?
Currently, November is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £128). Flying from Panama City to Mexico City in March is currently the most expensive (average of £259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Mexico City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 12 December 2025.
Top airline flying from Panama City to Mexico City
Discover the top airline that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 12 December 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Panama City to Mexico City?
Cheapflights helps you search for flights from Panama City to Mexico City via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.
Why should you use Cheapflights to find cheap flight tickets from Panama City to Mexico City?
Millions of users choose and trust Cheapflights to book the best flight deals from Panama City to Mexico City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Panama City to Mexico City with no change fees?
Yes! Cheapflights helps users easily find flights from Panama City to Mexico City with no change fees.
Can Cheapflights notify me if prices for flights from Panama City to Mexico City become cheaper?
Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Mexico City from Panama City today and book when prices fit your budget.
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