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Cheap flights from Manchester to Panama City, Florida from £3,952

MAN — ECP
14 Dec — 21 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama City

Enter your travel dates to find the best prices.

Best flights from Manchester to Panama City

Sat 2/105:50 -
2 stops15h 30m
Sat 2/118:55 -
2 stops32h 45m
Deal found 11/11£3,952

Find flight deals from Manchester to Panama City

Round-trip from

£3,952
Virgin Atlantic
  • Virgin Atlantic
  • 2/1-2/1
  • 4 total stops
  • 48h 15m total
  • Manchester to Panama City
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Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

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ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Sat 2/1

05:50-15:20

2 stops15h 30m

Panama City NW Florida Beaches

Sat 2/1

18:55-09:40

2 stops32h 45m

£3,952

Flights are sorted by cheapest return flights first.

Deals found on 11/11

Sorted by cheapest first

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated return price

Reviews of airlines servicing Panama City

Read reviews from past customers who have flown with Virgin Atlantic from Manchester to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
698 reviews
Check prices

Entertainment

7.5

Boarding

7.7

Comfort

7.3

Food

6.9

Overall

7.5

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.
Virgin Atlantic
7.5
Good
698 reviews
Virgin Atlantic
7.5
Good
698 reviews
Check prices

Entertainment

7.5

Boarding

7.7

Comfort

7.3

Food

6.9

Overall

7.5

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Related info for your journey

  • How long is the flight from Manchester to Panama City, Florida?

    Virgin Atlantic can get you from Manchester to Panama City, Florida in just under 15h 30m. Your travel time can differ by up to . There are 4307 mi between Manchester and Panama City, Florida.

  • What is the cheapest airline to fly from Manchester to Panama City, Florida round-trip?

    Virgin Atlantic, at £713, was found to be the cheapest airline from Manchester to Panama City, Florida..

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Manchester to Panama City

AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£713Average£867FlexibilityNo cancel feeOn-time72%
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Can Cheapflights find flights from Manchester to Panama City with no change fees?

Need flexible booking options for your flight to Panama City from Manchester? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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