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Cheap flights from Manchester to Panama City, Florida from £506

MAN — ECP
15 Oct — 22 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama City

Tue 13/1009:35 -
2 stops19h 43m
Fri 6/1114:35 -
2 stops36h 55m
Deal found 14/9£616
Sun 11/1019:30 -
2 stops31h 36m
Fri 6/1111:21 -
2 stops40h 09m
Deal found 14/9£636
Mon 28/906:05 -
2 stops36h 58m
Wed 14/1006:20 -
2 stops29h 15m
Deal found 14/9£665
Sun 11/1009:00 -
2 stops43h 18m
Thu 5/1116:55 -
2 stops34h 05m
Deal found 14/9£667
Sun 11/1009:00 -
2 stops43h 18m
Wed 4/1111:30 -
2 stops15h 30m
Deal found 14/9£708
Tue 13/1009:35 -
2 stops19h 43m
Wed 4/1114:45 -
2 stops21h 50m
Deal found 14/9£718
Mon 28/913:00 -
1 stop14h 03m
Thu 15/1016:30 -
1 stop10h 20m
Deal found 14/9£719
Tue 29/912:10 -
2 stops16h 55m
Thu 15/1011:21 -
2 stops16h 39m
Deal found 14/9£720
Tue 29/913:45 -
2 stops15h 20m
Wed 14/1013:35 -
1 stop11h 40m
Deal found 14/9£724
Wed 30/912:10 -
2 stops28h 24m
Wed 14/1013:35 -
2 stops21h 20m
Deal found 14/9£728
Tue 29/905:55 -
2 stops23h 10m
Sun 11/1018:20 -
1 stop32h 30m
Deal found 14/9£730

Find flight deals from Manchester to Panama City

Round-trip from

£616

One-way from

£506
Scandinavian Airlines
  • Scandinavian Airlines
  • 13/10-6/11
  • 4 total stops
  • 56h 38m total
  • Manchester to Panama City
Search Deals
Virgin Atlantic
  • Virgin Atlantic
  • 4/12-31/12
  • 2 total stops
  • 23h 27m total
  • Manchester to Panama City
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Fri 4/12

05:50-23:17

2 stops23h 27m

Panama City NW Florida Beaches

Wed 31/12

00:00-07:00

Nonstop0h 00m

£506
Fastest return journey

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Fri 4/12

14:55-23:17

1 stop14h 22m

Panama City NW Florida Beaches

Wed 31/12

00:00-07:00

Nonstop0h 00m

£509

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Fri 4/12

19:15-10:34

3 stops45h 19m

Panama City NW Florida Beaches

Wed 31/12

00:00-07:00

Nonstop0h 00m

£511

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Mon 12/10

13:00-23:18

1 stop16h 18m

Panama City NW Florida Beaches

Fri 6/11

17:37-10:30

1 stop10h 53m

£821

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Mon 28/9

13:00-23:25

1 stop16h 25m

Panama City NW Florida Beaches

Thu 15/10

16:30-13:15

2 stops14h 45m

£962

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Sun 27/9

11:15-21:03

1 stop15h 48m

Panama City NW Florida Beaches

Thu 15/10

16:30-08:50

1 stop10h 20m

£991

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Fri 25/9

09:35-23:25

2 stops19h 50m

Panama City NW Florida Beaches

Mon 12/10

16:30-08:55

2 stops34h 25m

£1,034

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Sat 26/9

13:15-23:05

1 stop15h 50m

Panama City NW Florida Beaches

Tue 13/10

09:19-08:50

1 stop17h 31m

£1,042

ManchesterPanama City

MAN Manchester - ECP Panama City NW Florida Beaches

MANECP

Manchester

Sat 26/9

13:15-23:05

1 stop15h 50m

Panama City NW Florida Beaches

Sat 17/10

09:19-08:50

1 stop17h 31m

£1,072

Flights are sorted by cheapest return flights first.

Deals found on 14/9

Sorted by cheapest first

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated return price

Reviews of airlines servicing Panama City

Read reviews from past customers who have flown with Virgin Atlantic from Manchester to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.4
Good
694 reviews
Check prices

Boarding

7.7

Food

6.9

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.
Virgin Atlantic
7.4
Good
694 reviews
Virgin Atlantic
7.4
Good
694 reviews
Check prices

Boarding

7.7

Food

6.9

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Related info for your journey

  • How long is the flight from Manchester to Panama City, Florida?

    Delta, KLM, and Scandinavian Airlines can get you from Manchester to Panama City, Florida in just under 14h 03m. Your travel time can differ by up to 5h 47m. There are 4307 mi between Manchester and Panama City, Florida. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What is the cheapest airline to fly from Manchester to Panama City, Florida round-trip?

    Virgin Atlantic, at £556, was found to be the cheapest airline from Manchester to Panama City, Florida..

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Manchester to Panama City

AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£556Average£769FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

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Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama City?

Cheapflights simply makes it quick and affordable to book flights from Manchester to Panama City by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Manchester to Panama City with no change fees?

Need flexible booking options for your flight to Panama City from Manchester? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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