Cheap flights from London Luton Airport to Panama City from £229

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/4. Fares are subject to change and may not be available on all flights or dates of travel.
LTN — PTY
23 Apr — 30 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Luton to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Luton to Panama City
Explore the most affordable flight options available from Luton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 March 2026.

Thu 7/505:40
LTN
-
PTY
2 stops19h 00m
Multiple Airlines
Thu 14/520:25
PTY
-
LTN
2 stops22h 25m
Multiple Airlines
Deal found 23/3£592
Mon 4/507:55
LTN
-
PTY
1 stop16h 45m
Multiple Airlines
Tue 19/520:25
PTY
-
LTN
1 stop21h 20m
Multiple Airlines
Deal found 20/3£613
Mon 4/507:55
LTN
-
PTY
1 stop16h 45m
Multiple Airlines
Mon 18/520:25
PTY
-
LTN
1 stop16h 40m
Multiple Airlines
Deal found 24/3£616
Sat 16/508:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Sat 23/520:25
PTY
-
LTN
1 stop15h 45m
Multiple Airlines
Deal found 20/3£617
Thu 14/508:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Thu 21/520:25
PTY
-
LTN
1 stop15h 45m
Multiple Airlines
Deal found 20/3£634
Mon 20/407:55
LTN
-
PTY
1 stop16h 45m
Multiple Airlines
Mon 27/420:25
PTY
-
LTN
1 stop16h 40m
Multiple Airlines
Deal found 21/3£635
Mon 13/407:55
LTN
-
PTY
1 stop16h 45m
Multiple Airlines
Tue 28/420:25
PTY
-
LTN
1 stop21h 20m
Multiple Airlines
Deal found 23/3£636
Tue 14/408:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Tue 28/420:25
PTY
-
LTN
1 stop21h 20m
Multiple Airlines
Deal found 23/3£637
Sun 12/408:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Tue 28/420:25
PTY
-
LTN
1 stop21h 20m
Multiple Airlines
Deal found 23/3£640
Sat 18/408:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Tue 28/420:25
PTY
-
LTN
1 stop21h 20m
Multiple Airlines
Deal found 23/3£641

Find flight deals from Luton to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Luton (LTN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 March 2026.

Round-trip from

£592

One-way from

£229

Popular in

December

Cheapest in

June

Average price

£690
7/5-14/5
  • 7/5-14/5
  • 4 total stops
  • 41h 25m total
  • London to Panama City
14/4
  • 14/4
  • 2 total stops
  • 33h 20m total
  • London to Panama City
Highest demand for flights based on searches. 3% potential increase in price (£21 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Luton to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 March 2026.
Use the filters below to find and compare flights from London Luton Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 18/4

08:00-18:40

1 stop16h 40m

Panama City Tocumen Intl

Tue 28/4

20:25-23:45

1 stop21h 20m

£641
Fastest return journey

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Thu 7/5

08:00-18:40

1 stop16h 40m

Panama City Tocumen Intl

Thu 14/5

20:25-18:10

1 stop15h 45m

£653

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 16/5

12:45-18:40

2 stops35h 55m

Panama City Tocumen Intl

Sat 23/5

20:25-23:40

2 stops21h 15m

£664

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Mon 20/4

07:55-18:40

1 stop16h 45m

Panama City Tocumen Intl

Mon 27/4

20:25-19:05

1 stop16h 40m

£719

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 15/4

13:35-16:35

2 stops33h 00m

Panama City Tocumen Intl

Fri 15/5

20:25-23:50

2 stops21h 25m

£767

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 14/4

08:00-00:35

2 stops22h 35m

Panama City Tocumen Intl

Tue 28/4

20:25-23:45

1 stop21h 20m

£795

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 6/5

18:10-09:15

2 stops21h 05m

Panama City Tocumen Intl

Wed 27/5

21:30-19:00

1 stop15h 30m

£826
Cheapest one-way

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 13/6

18:15-00:35

2 stops36h 20m

£272

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 15/5

19:00-00:35

2 stops35h 35m

£283

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 14/4

13:40-20:00

1 stop36h 20m

£293

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Luton to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Luton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Luton to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from London Luton?

    For a flight from London Luton to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from London Luton per day. 0 airlines have flights to Panama City Tocumen Intl from London Luton on a regular basis.

  • Can I find deals for flights from Luton to Panama City that include hotel bookings?

    Yes. In addition to deals on Luton to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Luton to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Luton to Panama City.

  • Can I find deals for business class flights from Luton to Panama City?

    Yes. Cheapflights offers flight deals from Luton to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

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Alternative routes for Luton to Panama City

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How does Cheapflights help users find flights from Luton to Panama City?

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Why should you use Cheapflights to find cheap flight tickets from Luton to Panama City?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Luton to Panama City.

Can Cheapflights find flights from Luton to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Luton to Panama City flexibly with Cheapflights today.

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