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Cheap flights from London Luton Airport to Panama City from £343

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/1. Fares are subject to change and may not be available on all flights or dates of travel.
LTN — PTY
23 Nov — 30 Nov1
1 adult
1 adult, Economy, 0 bags

Find flight deals from Luton to Panama City

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Cheapest flights from Luton to Panama City
Explore the most affordable flight options available from Luton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 October 2025.

Sun 7/1213:15LTN - PTY
2 stops35h 30mMultiple Airlines
Sun 14/1221:30PTY - LTN
2 stops18h 10mMultiple Airlines
Deal found 23/10£665
Fri 5/1214:55LTN - PTY
2 stops33h 50mMultiple Airlines
Fri 12/1221:30PTY - LTN
2 stops18h 30mMultiple Airlines
Deal found 21/10£699
Mon 10/1106:20LTN - PTY
3 stops31h 30mMultiple Airlines
Thu 20/1119:05PTY - LTN
2 stops21h 45mMultiple Airlines
Deal found 21/10£781
Thu 20/1110:45LTN - PTY
2 stops34h 45mMultiple Airlines
Thu 27/1122:20PTY - LTN
2 stops19h 05mMultiple Airlines
Deal found 21/10£816
Wed 5/1120:50LTN - PTY
2 stops24h 55mMultiple Airlines
Tue 11/1121:30PTY - LTN
2 stops17h 40mMultiple Airlines
Deal found 23/10£838
Mon 1/1213:25LTN - PTY
2 stops35h 45mMultiple Airlines
Wed 10/1218:45PTY - LTN
1 stop17h 15mMultiple Airlines
Deal found 22/10£841
Mon 1/1206:15LTN - PTY
1 stop15h 30mMultiple Airlines
Thu 4/1219:05PTY - LTN
2 stops22h 20mMultiple Airlines
Deal found 22/10£877

Cheap flight deals from Luton to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Luton (LTN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 October 2025.

Round-trip from

£665

One-way from

£343

Popular in

December

Cheapest in

June

Average price

£693
7/12-14/12
  • 7/12-14/12
  • 4 total stops
  • 53h 40m total
  • London to Panama City
Search Deals
5/12
  • 5/12
  • 2 total stops
  • 28h 00m total
  • London to Panama City
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£38 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Luton to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 October 2025.
Use the filters below to find and compare flights from London Luton Airport to Panama City that are best for you.

Fly from

Luton

Fly to

Panama City

Route

Depart

Return

Price

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 7/12

13:15-19:45

2 stops35h 30m

Panama City Tocumen Intl

Sun 14/12

21:30-20:40

2 stops18h 10m

£665

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 5/12

14:55-19:45

2 stops33h 50m

Panama City Tocumen Intl

Fri 12/12

21:30-21:00

2 stops18h 30m

£699

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 6/2

18:35-19:55

2 stops30h 20m

Panama City Tocumen Intl

Sun 15/2

22:20-16:35

1 stop13h 15m

£808

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 5/11

20:50-16:45

2 stops24h 55m

Panama City Tocumen Intl

Tue 11/11

21:30-20:10

2 stops17h 40m

£838

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Mon 1/12

13:25-20:10

2 stops35h 45m

Panama City Tocumen Intl

Wed 10/12

18:45-17:00

1 stop17h 15m

£841

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Thu 4/12

07:15-19:45

2 stops17h 30m

Panama City Tocumen Intl

Mon 8/12

19:05-21:35

2 stops21h 30m

£883

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Thu 20/11

06:05-08:50

3 stops31h 45m

Panama City Tocumen Intl

Thu 27/11

19:05-18:10

2 stops18h 05m

£883

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 27/2

21:40-19:50

2 stops27h 10m

Panama City Tocumen Intl

Wed 11/3

21:45-23:10

1 stop20h 25m

£931

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sun 18/1

14:40-19:50

2 stops34h 10m

£343

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 5/12

20:50-19:50

2 stops28h 00m

£343

Flights are sorted by cheapest return flights first.

Deals found on 21/10

Showing 1-10 of 16 results
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Best time to book a flight from Luton to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Luton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Luton to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from London Luton?

    For a flight from London Luton to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from London Luton per day. 0 airlines have flights to Panama City Tocumen Intl from London Luton on a regular basis.

  • Can I find deals for flights from Luton to Panama City that include hotel bookings?

    Yes. In addition to deals on Luton to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Luton to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Luton to Panama City.

  • Can I find deals for business class flights from Luton to Panama City?

    Yes. Cheapflights offers flight deals from Luton to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

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Alternative routes for Luton to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to Panama City flights
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Fly with Cheapflights

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How does Cheapflights help users find flights from Luton to Panama City?

When you search for this flight from Luton to Panama City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Luton to Panama City?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Luton to Panama City.

Can Cheapflights find flights from Luton to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Luton to Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Luton to Panama City become cheaper?

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