Cheap flights from London Luton Airport to Panama City from £276

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/3. Fares are subject to change and may not be available on all flights or dates of travel.
LTN — PTY
23 Jan — 30 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Luton to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Luton to Panama City
Explore the most affordable flight options available from Luton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 December 2025.

Mon 29/1206:15LTN - PTY
1 stop18h 30mMultiple Airlines
Tue 13/115:39PTY - LTN
2 stops21h 11mMultiple Airlines
Deal found 23/12£1,066
Tue 30/1220:50LTN - PTY
2 stops28h 00mMultiple Airlines
Sat 3/109:45PTY - LTN
2 stops21h 10mMultiple Airlines
Deal found 23/12£1,228
Sun 28/1208:50LTN - PTY
2 stops36h 40mMultiple Airlines
Mon 12/122:20PTY - LTN
1 stop18h 30mMultiple Airlines
Deal found 23/12£1,400
Tue 30/1220:50LTN - PTY
2 stops28h 00mMultiple Airlines
Mon 5/122:05PTY - LTN
1 stop18h 25mMultiple Airlines
Deal found 23/12£1,435
Tue 23/1217:10LTN - PTY
2 stops32h 00mMultiple Airlines
Sat 31/121:45PTY - LTN
1 stop20h 30mMultiple Airlines
Deal found 23/12£1,686
Tue 23/1207:10LTN - PTY
1 stop18h 00mMultiple Airlines
Wed 7/122:05PTY - LTN
1 stop14h 50mMultiple Airlines
Deal found 22/12£2,333

Find flight deals from Luton to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Luton (LTN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 December 2025.

Round-trip from

£620

One-way from

£276

Popular in

December

Cheapest in

November

Average price

£857
18/2-10/3
  • 18/2-10/3
  • 4 total stops
  • 67h 10m total
  • London to Panama City
21/3
  • 21/3
  • 2 total stops
  • 23h 45m total
  • London to Panama City
Highest demand for flights based on searches. 5% potential increase in price (£30 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customise your flight search to find flights from Luton to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 December 2025.
Use the filters below to find and compare flights from London Luton Airport to Panama City that are best for you.

Fly from

Luton

Fly to

Panama City

Route

Depart

Return

Price

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 18/2

14:40-01:00

2 stops39h 20m

Panama City Tocumen Intl

Tue 10/3

02:55-11:45

2 stops27h 50m

£620

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 27/1

06:25-16:30

1 stop15h 05m

Panama City Tocumen Intl

Sun 8/2

18:45-13:20

1 stop13h 35m

£775

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Mon 30/3

07:00-00:45

2 stops23h 45m

Panama City Tocumen Intl

Sun 5/4

11:05-12:45

2 stops19h 40m

£799

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 3/3

06:50-01:00

2 stops23h 10m

Panama City Tocumen Intl

Tue 10/3

21:30-20:20

1 stop17h 50m

£813

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Mon 26/1

07:20-20:10

1 stop17h 50m

Panama City Tocumen Intl

Sun 8/2

18:45-16:35

2 stops16h 50m

£828

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Wed 21/1

07:00-19:55

2 stops17h 55m

Panama City Tocumen Intl

Wed 28/1

22:20-21:50

1 stop18h 30m

£896

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Tue 7/4

07:00-00:10

2 stops23h 10m

Panama City Tocumen Intl

Thu 7/5

17:25-17:55

2 stops18h 30m

£932

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 16/1

09:05-08:50

3 stops28h 45m

Panama City Tocumen Intl

Mon 19/1

10:25-20:10

3 stops28h 45m

£941

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Sat 21/3

06:15-01:00

2 stops23h 45m

£276

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Thu 23/4

07:00-00:10

2 stops23h 10m

£295

Flights are sorted by cheapest return flights first.

Deals found on 22/12

Showing 1-10 of 16 results
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Best time to book a flight from Luton to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Luton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Luton to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from London Luton?

    For a flight from London Luton to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from London Luton per day. 0 airlines have flights to Panama City Tocumen Intl from London Luton on a regular basis.

  • Can I find deals for flights from Luton to Panama City that include hotel bookings?

    Yes. In addition to deals on Luton to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Luton to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Luton to Panama City.

  • Can I find deals for business class flights from Luton to Panama City?

    Yes. Cheapflights offers flight deals from Luton to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

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Alternative routes for Luton to Panama City

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How does Cheapflights help users find flights from Luton to Panama City?

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It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Luton to Panama City.

Can Cheapflights find flights from Luton to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Luton to Panama City flexibly with Cheapflights today.

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