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Cheap flights from Brussels Bruxelles-National Airport to Panama City from £454

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/5. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — PTY
5 May — 12 May1
1 adult

Cheap flight deals from Bruxelles-National to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 April 2025.

Round-trip from

£454

Popular in

December

Cheapest in

March

Average price

£547
United Airlines
  • United Airlines
  • 26/5-11/6
  • 2 total stops
  • 30h 16m total
  • Brussels to Panama City
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (£63 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Bruxelles-National to Panama City

Cheapest flights from Bruxelles-National to Panama City
Explore the most affordable flight options available from Bruxelles-National to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.

Mon 26/511:15BRU - PTY
1 stop15h 16mUnited Airlines
Wed 11/609:45PTY - BRU
1 stop15h 00mUnited Airlines
Deal found 29/4£454
Wed 11/610:25BRU - PTY
1 stop13h 25mKLM
Mon 16/618:50PTY - BRU
1 stop31h 50mKLM
Deal found 29/4£508
Fri 23/510:45BRU - PTY
1 stop14h 55mAir Europa
Sun 15/620:25PTY - BRU
1 stop14h 15mAir Europa
Deal found 29/4£532
Sat 24/510:45BRU - PTY
2 stops33h 03mDelta
Wed 11/614:23PTY - BRU
1 stop35h 17mDelta
Deal found 29/4£568
Wed 3/1207:00BRU - PTY
1 stop15h 50mIberia
Mon 29/1218:20PTY - BRU
1 stop22h 15mIberia
Deal found 29/4£600
Wed 3/1207:50BRU - PTY
2 stops39h 25mTurkish Airlines
Mon 29/1218:55PTY - BRU
1 stop21h 05mTurkish Airlines
Deal found 29/4£630
Wed 11/609:30BRU - PTY
2 stops24h 10mMultiple Airlines
Mon 16/611:05PTY - BRU
3 stops24h 35mMultiple Airlines
Deal found 29/4£633

Cheapflights Fare Finder

Customise your flight search to find flights from Bruxelles-National to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 April 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

Fly from

Bruxelles-National

Fly to

Panama City

Route

Depart

Return

Price

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Mon 26/5

11:15-19:31

1 stop15h 16m

Panama City Tocumen Intl

Wed 11/6

09:45-07:45

1 stop15h 00m

£454

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Mon 26/5

11:15-19:31

1 stop15h 16m

Panama City Tocumen Intl

Mon 9/6

09:45-07:45

1 stop15h 00m

£455

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Wed 11/6

10:25-16:50

1 stop13h 25m

Panama City Tocumen Intl

Mon 16/6

18:50-09:40

1 stop31h 50m

£508

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Fri 23/5

10:45-18:40

1 stop14h 55m

Panama City Tocumen Intl

Sun 15/6

20:25-17:40

1 stop14h 15m

£532

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Sat 24/5

10:45-12:48

2 stops33h 03m

Panama City Tocumen Intl

Wed 11/6

14:23-08:40

1 stop35h 17m

£568

Flights are sorted by cheapest return flights first.

Deals found on 29/4

Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Brussels Bruxelles-National Airport to Panama City

How far ahead should I book a flight from Brussels Bruxelles-National Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Bruxelles-National to Panama City. Price data was last updated on 25 April 2025.

The best time to book flights from Brussels Bruxelles-National Airport to Panama City is 55 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City?

Currently, April is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City (average of £763). Flying from Brussels Bruxelles-National Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 30 April 2025.
Delta
8.0
Very Good
7,934 reviews
Check prices

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Matt,Sept 2023

LAX - DAL

The crew was exceptional. The best crew on all 4 flight we took on this trip.
Delta
8.0
Very Good
7,934 reviews
Delta
8.0
Very Good
7,934 reviews
Check prices

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Matt,Sept 2023

LAX - DAL

The crew was exceptional. The best crew on all 4 flight we took on this trip.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very Good
7,934 reviews
Check prices

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Matt,Sept 2023

LAX - DAL

The crew was exceptional. The best crew on all 4 flight we took on this trip.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very Good
7,934 reviews
Check prices

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Matt,Sept 2023

LAX - DAL

The crew was exceptional. The best crew on all 4 flight we took on this trip.
Air Europa
6.9
Okay
510 reviews
Delta
8.0
Very Good
7,934 reviews
Check prices

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Matt,Sept 2023

LAX - DAL

The crew was exceptional. The best crew on all 4 flight we took on this trip.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    If you book a flight to Panama City from Brussels Bruxelles-National, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Brussels Bruxelles-National to Tocumen Intl per day from 0 different airlines.

  • What are the cheapest airlines flying from Brussels Bruxelles-National Airport to Panama City round-trip?

    According to our current data, United Airlines (£454), KLM (£508), and Air Europa (£532) offers the cheapest pricing from Brussels Bruxelles-National Airport to Panama City. United Airlines is currently priced 14% below the average price you’ll pay for this route.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City (average of £763). Flying from Brussels Bruxelles-National Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
San Blas

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Can Cheapflights notify me if prices for flights from Bruxelles-National to Panama City become cheaper?

Yes! Start tracking prices for Bruxelles-National to Panama City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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