Cheap flights from Panama City to Istanbul Airport from £665
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/11. Fares are subject to change and may not be available on all flights or dates of travel.
Cheap flight deals from Panama City to Istanbul
Cheapest flights from Panama City to IstanbulExplore the most affordable flight options available from Panama City to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 October 2026.
Explore the most affordable flight options available from Panama City to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 October 2026.
Best flights from Panama City to IstanbulDiscover carefully curated flight deals from Panama City to Istanbul that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 10 October 2026.
Discover carefully curated flight deals from Panama City to Istanbul that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 10 October 2026.
Direct flights from Panama City to IstanbulExplore direct flight options from Panama City to Istanbul based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 October 2026.
Explore direct flight options from Panama City to Istanbul based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 October 2026.
Last-minute flights from Panama City to IstanbulDiscover last-minute flight deals from Panama City to Istanbul. Data last updated 10 October 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Istanbul. Data last updated 10 October 2026 and is based on user searches.
One-way flights from Panama City to IstanbulSearch for one-way flight options from Panama City to Istanbul. Find affordable one-way fares based on user searches. Data last updated 10 October 2026.
Search for one-way flight options from Panama City to Istanbul. Find affordable one-way fares based on user searches. Data last updated 10 October 2026.
Find flight deals from Panama City to Istanbul
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 October 2026.
Cheapflights Fare Finder
Use the filters below to find and compare flights from Panama City to Istanbul Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Thu 19/11
22:30-16:55
2 stops34h 25m
Istanbul
Wed 31/12
00:00-17:00
Nonstop0h 00m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Mon 9/11
22:30-16:55
2 stops34h 25m
Istanbul
Mon 23/11
07:15-20:20
1 stop21h 05m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Wed 21/10
20:25-13:55
1 stop33h 30m
Istanbul
Mon 2/11
16:35-19:45
1 stop35h 10m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Wed 21/10
20:25-13:55
1 stop33h 30m
Istanbul
Tue 10/11
16:35-19:45
1 stop35h 10m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Fri 26/3
21:30-13:55
1 stop32h 25m
Istanbul
Fri 9/4
15:35-18:40
1 stop35h 05m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Mon 23/11
22:00-18:45
Nonstop12h 45m
Istanbul
Wed 31/12
00:00-17:00
Nonstop0h 00m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Thu 19/11
18:50-15:35
Nonstop12h 45m
Istanbul
Wed 31/12
00:00-17:00
Nonstop0h 00m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Mon 9/11
16:41-18:10
2 stops41h 29m
Istanbul
Mon 23/11
06:30-20:02
2 stops45h 32m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Fri 23/10
22:20-19:05
Nonstop12h 45m
Istanbul
Wed 31/12
00:00-17:00
Nonstop0h 00m
Panama CityIstanbul
PTY Panama City Tocumen Intl - IST Istanbul
PTYIST
Panama City Tocumen Intl
Sun 20/12
18:50-15:35
Nonstop12h 45m
Istanbul
Wed 31/12
00:00-17:00
Nonstop0h 00m
Best time to book a flight from Panama City to Istanbul
Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama City with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Istanbul Airport
How far ahead should I book a flight from Panama City to Istanbul Airport?
To ensure you get the cheapest price possible for a flight from Panama City to Istanbul Airport, you should look to book at least 62 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Panama City to Istanbul Airport?
Currently, March is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of £908). Flying from Panama City to Istanbul Airport in August is currently the most expensive (average of £1,141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to IST?
When flying from Panama City to Istanbul Airport, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Panama City to Istanbul delayed?
About 23% of weekly flights between Panama City and Istanbul have experienced delays in the past year, with the average delay time being 164 minutes.
What is the most punctual flight time for Panama City to Istanbul flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Istanbul flights?
Over the past year, Turkish Airlines have had the lowest number of delays on this route, with just 23% of flights being delayed.
Related info for your journey
Find useful and relevant information for your journey from Panama City to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Travelling to a place near Istanbul Airport?
Book flights to Istanbul Airport if you plan to visit one of these locationsBrowse thousands of different options on Cheapflights for your next trip
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Complete your trip
Complete your trip to Istanbul by adding a car hire and/or hotel booking to your travel itinerary.
Direct flights to Türkiye (Turkey)
Book a non-stop flight to one of these other cities located in Türkiye (Turkey).
Search flights from Panama City to Istanbul by cabin class
Find flights from Panama City to Istanbul, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Istanbul
Explore flights to Istanbul departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 10 October 2026.
Panama City and Istanbul flights
Browse other Panama City and Istanbul flight options. Last updated on 10 October 2026.
Popular flight searches
Check out other popular destinations found by fellow travellers in 2026
Fly with Cheapflights
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How does Cheapflights help users find flights from Panama City to Istanbul?
Cheapflights helps you search for flights from Panama City to Istanbul via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.
Why should you use Cheapflights to find cheap flight tickets from Panama City to Istanbul?
Cheapflights helps you find that perfect flight to Istanbul from Panama City by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!
Can Cheapflights find flights from Panama City to Istanbul with no change fees?
Need flexible booking options for your flight to Istanbul from Panama City? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.
Can Cheapflights notify me if prices for flights from Panama City to Istanbul become cheaper?
Not ready to book yet? You can track prices for flights from Panama City to Istanbul on Cheapflights with our Price Alert feature and get notified when better prices are available.