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Cheap flights from Panama City to Brussels Bruxelles-National Airport from £687

PTY — BRU
13 Nov — 20 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Bruxelles-National

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Bruxelles-National

Wed 11/1118:45 -
1 stop13h 30m
Wed 18/1108:05 -
2 stops18h 15m
Deal found 13/10£707
Fri 20/1116:41 -
2 stops56h 34m
Thu 3/1210:10 -
2 stops39h 52m
Deal found 14/10£810
Fri 20/1122:30 -
2 stops17h 50m
Mon 23/1108:05 -
2 stops18h 15m
Deal found 11/10£811
Fri 25/1223:55 -
1 stop26h 10m
Fri 8/111:15 -
2 stops35h 57m
Deal found 11/10£814
Sat 17/1010:00 -
2 stops38h 45m
Mon 26/1011:55 -
2 stops37h 07m
Deal found 9/10£972
Tue 22/1221:30 -
1 stop14h 15m
Sat 2/110:45 -
1 stop15h 00m
Deal found 13/10£999
Thu 17/1221:30 -
1 stop14h 15m
Mon 28/1218:55 -
1 stop30h 50m
Deal found 11/10£1,031

Find flight deals from Panama City to Bruxelles-National

Round-trip from

£810

One-way from

£687

Popular in

April

Cheapest in

March

Average price

£699
United Airlines
  • United Airlines
  • 20/11-3/12
  • 4 total stops
  • 96h 26m total
  • Panama City to Brussels
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Turkish Airlines
  • Turkish Airlines
  • 12/1-31/12
  • 1 total stop
  • 37h 15m total
  • Panama City to Brussels
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 1% potential price decrease (£7 potential savings vs. average return price).
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Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

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Route

Depart

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Price

Cheapest return flight

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Tue 12/1

22:00-17:15

1 stop37h 15m

Brussels Bruxelles-National

Wed 31/12

00:00-18:00

Nonstop0h 00m

£687

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Wed 11/11

18:45-14:15

1 stop13h 30m

Brussels Bruxelles-National

Wed 18/11

08:05-20:20

2 stops18h 15m

£707

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Fri 20/11

16:41-07:15

2 stops56h 34m

Brussels Bruxelles-National

Thu 3/12

10:10-20:02

2 stops39h 52m

£810

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Fri 20/11

22:30-22:20

2 stops17h 50m

Brussels Bruxelles-National

Mon 23/11

08:05-20:20

2 stops18h 15m

£811

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Fri 25/12

23:55-08:05

1 stop26h 10m

Brussels Bruxelles-National

Fri 8/1

11:15-20:02

1 stop14h 47m

£814

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Tue 22/12

21:30-17:45

1 stop14h 15m

Brussels Bruxelles-National

Sat 2/1

10:45-19:45

1 stop15h 00m

£999

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Thu 17/12

21:30-09:50

1 stop30h 20m

Brussels Bruxelles-National

Mon 28/12

18:55-19:45

1 stop30h 50m

£1,037

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Thu 17/12

18:50-10:35

1 stop33h 45m

Brussels Bruxelles-National

Mon 28/12

06:35-17:10

2 stops40h 35m

£1,069
Fastest return journey

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sat 5/12

21:30-17:45

1 stop14h 15m

Brussels Bruxelles-National

Wed 31/12

00:00-18:00

Nonstop0h 00m

£1,559

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Thu 3/12

21:30-17:45

1 stop14h 15m

Brussels Bruxelles-National

Wed 31/12

00:00-18:00

Nonstop0h 00m

£1,559

Flights are sorted by cheapest return flights first.

Deals found on 13/10

Sorted by cheapest first

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

To ensure you get the cheapest price possible for a flight from Panama City to Brussels Bruxelles-National Airport, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, March is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of £631). Flying from Panama City to Brussels Bruxelles-National Airport in April is currently the most expensive (average of £867). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

  • What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Brussels Bruxelles-National. 0 airlines have flights from Tocumen Intl to Brussels Bruxelles-National on a regular basis. Booking flights from Panama City Tocumen Intl to Brussels Bruxelles-National should not be difficult; the airport handles an average of 0 outbound flights to Brussels Bruxelles-National per day.

  • How long is the flight from Panama City to Brussels Bruxelles-National Airport?

    For as low as £707, KLM can have you in Brussels Bruxelles-National Airport from Panama City in 13h 30m. Panama City and Brussels Bruxelles-National Airport are separated by a distance of 5462 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

  • Can I find deals for business class flights from Panama City to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

    Currently, March is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of £631). Flying from Panama City to Brussels Bruxelles-National Airport in April is currently the most expensive (average of £867). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Leuven
Charleroi
Mechelen
Mons
Namur
Hasselt
Dinant
Ypres
Spa
Zaventem

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Deals for Panama City to Bruxelles-National flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

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Can Cheapflights notify me if prices for flights from Panama City to Bruxelles-National become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Bruxelles-National from Panama City today and book when prices fit your budget.

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