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Cheap flights from London to Panama from £280

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/3. Fares are subject to change and may not be available on all flights or dates of travel.
LON — PTY
25 Mar — 1 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from London to Panama

Enter your travel dates to find the best prices.

Cheapest flights from London to Panama
Explore the most affordable flight options available from London to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 February 2026.

Thu 4/606:00
STN
-
PTY
1 stop18h 40m
Multiple Airlines
Thu 11/620:25
PTY
-
STN
1 stop21h 30m
Multiple Airlines
Deal found 19/2£582
Thu 7/508:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Thu 21/520:25
PTY
-
LTN
1 stop15h 30m
Multiple Airlines
Deal found 20/2£584
Mon 9/321:40
LHR
-
PTY
1 stop21h 20m
Avianca
Mon 16/314:55
PTY
-
LHR
1 stop18h 40m
Avianca
Deal found 20/2£593
Mon 20/422:05
LHR
-
PTY
1 stop17h 10m
Avianca
Sun 26/417:55
PTY
-
LHR
1 stop15h 40m
Avianca
Deal found 20/2£595
Sun 22/221:40
LHR
-
PTY
2 stops26h 15m
Avianca
Mon 16/314:55
PTY
-
LHR
1 stop18h 40m
Avianca
Deal found 19/2£597
Mon 25/510:00
LGW
-
PTY
1 stop14h 40m
Air Europa
Wed 3/620:25
PTY
-
LGW
1 stop14h 00m
Air Europa
Deal found 22/2£598
Mon 23/221:40
LHR
-
PTY
2 stops26h 15m
Avianca
Thu 2/405:30
PTY
-
LHR
2 stops28h 05m
Avianca
Deal found 23/2£601
Wed 15/406:00
LGW
-
PTY
1 stop18h 40m
Multiple Airlines
Sun 19/420:25
PTY
-
LGW
1 stop20h 10m
Multiple Airlines
Deal found 22/2£602
Fri 17/406:30
LGW
-
PTY
3 stops40h 05m
Multiple Airlines
Wed 22/420:25
PTY
-
LGW
1 stop30h 35m
Multiple Airlines
Deal found 20/2£603
Wed 15/408:00
LTN
-
PTY
1 stop16h 40m
Multiple Airlines
Sun 19/420:25
PTY
-
LTN
1 stop35h 20m
Multiple Airlines
Deal found 22/2£604
Mon 23/308:35
LGW
-
PTY
1 stop16h 10m
Multiple Airlines
Mon 30/320:25
PTY
-
LGW
1 stop21h 30m
Multiple Airlines
Deal found 21/2£604
Mon 13/422:05
LHR
-
PTY
1 stop22h 10m
Avianca
Mon 4/515:10
PTY
-
LHR
1 stop18h 25m
Avianca
Deal found 21/2£605

Find flight deals from London to Panama

Keep the following information in mind while searching for London to Panama flight deals. Data was last updated 23 February 2026.

Round-trip from

£582

One-way from

£280

Popular in

December

Cheapest in

November

Average price

£699
4/6-11/6
  • 4/6-11/6
  • 2 total stops
  • 40h 10m total
  • London to Panama
Search Deals
24/3
  • 24/3
  • 1 total stop
  • 18h 25m total
  • London to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£24 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from London to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 23 February 2026.
Use the filters below to find and compare flights from London to Panama that are best for you.

Fly from

London

Fly to

Panama

Route

Depart

Return

Price

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Thu 28/5

22:05-10:30

2 stops18h 25m

Panama City Tocumen Intl

Tue 2/6

17:55-15:35

1 stop15h 40m

£609

LondonPanama City

LCY - PTY

LCYPTY

London City

Mon 9/3

07:45-16:30

1 stop13h 45m

Panama City Tocumen Intl

Mon 16/3

18:45-18:25

1 stop18h 40m

£615

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Tue 16/6

06:30-16:50

1 stop16h 20m

Panama City Tocumen Intl

Tue 14/7

21:55-21:25

1 stop17h 30m

£625

LondonPanama City

LGW - PTY

LGWPTY

London Gatwick

Tue 19/5

10:00-18:40

1 stop14h 40m

Panama City Tocumen Intl

Wed 27/5

20:25-09:00

1 stop30h 35m

£639

LondonPanama City

LTN - PTY

LTNPTY

London Luton

Fri 17/4

08:00-18:40

1 stop16h 40m

Panama City Tocumen Intl

Wed 22/4

20:25-19:00

1 stop16h 35m

£639

LondonPanama City

LGW - PTY

LGWPTY

London Gatwick

Wed 20/5

10:00-18:40

1 stop14h 40m

Panama City Tocumen Intl

Wed 27/5

20:25-09:00

1 stop30h 35m

£639

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Thu 7/5

06:50-19:31

2 stops18h 41m

Panama City Tocumen Intl

Mon 11/5

09:45-10:40

2 stops18h 55m

£648

LondonPanama City

LGW - PTY

LGWPTY

London Gatwick

Fri 6/3

10:00-19:45

1 stop14h 45m

Panama City Tocumen Intl

Thu 12/3

21:30-16:25

1 stop13h 55m

£648

LondonPanama City

LHR - PTY

LHRPTY

London Heathrow

Thu 23/4

06:50-19:31

2 stops18h 41m

Panama City Tocumen Intl

Mon 4/5

09:45-07:15

1 stop15h 30m

£652

LondonPanama City

LCY - PTY

LCYPTY

London City

Tue 16/6

09:20-16:50

1 stop13h 30m

Panama City Tocumen Intl

Tue 14/7

18:50-18:30

1 stop17h 40m

£657

Flights are sorted by cheapest return flights first.

Deals found on 22/2

Showing 1-10 of 60 results
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Best time to book a flight from London to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from London with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London to Panama

What is the cheapest month to book a flight from London to Panama?

Currently, May is the cheapest month in which you can book a flight from London to Panama (average of £388). Flying from London to Panama in December is currently the most expensive (average of £649). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated 23 February 2026.
See what other customers who have flown with KLM, United Airlines, andAir Europa from London to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,458 reviews
Check prices

Boarding

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Overall

7.7

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.7
Good
1,458 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Boarding

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Overall

7.7

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,342 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Boarding

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Overall

7.7

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Air Europa
6.9
Okay
590 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Boarding

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Overall

7.7

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Lufthansa
6.8
Okay
7,803 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Boarding

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Overall

7.7

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Avianca
6.6
Okay
2,497 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Boarding

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Overall

7.7

Comfort

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from London to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from London to Panama?

    Avianca, KLM, and Air Europa can get you from London to Panama in just under 13h 45m. Your travel time can differ by up to 4h 40m. There are 5271 mi between London and Panama. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from London to Panama?

    Most travelers choose London Heathrow - Panama City Tocumen Intl, London City - Panama City Tocumen Intl or London Gatwick - Panama City Tocumen Intl when deciding on the best route from London to Panama.

  • Can I find deals for flights from London to Panama that include hotel bookings?

    Yes. In addition to deals on London to Panama flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from London to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from London to Panama.

  • Can I find deals for business class flights from London to Panama?

    Yes. Cheapflights offers flight deals from London to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London to Panama?

    Currently, May is the cheapest month in which you can book a flight from London to Panama (average of £388). Flying from London to Panama in December is currently the most expensive (average of £649). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for London to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to San José flights
Gatwick to San José flights
London City to San José flights
Stansted to San José flights
Heathrow to Panama City flights
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Heathrow to Philip S.W.Goldson flights
Gatwick to Panama City flights
London City to Panama City flights
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Gatwick to Guatemala City flights
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Manchester to San José flights
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Heathrow to Liberia flights
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Manchester to Panama City flights
Gatwick to Philip S.W.Goldson flights
Gatwick to Liberia flights
London City to Managua flights
Heathrow to San Pedro Sula flights
Gatwick to San Pedro Sula flights
London City to San Salvador flights
London City to Liberia flights
Edinburgh to San José flights
Edinburgh to Managua flights
Stansted to San Salvador flights
London City to San Pedro Sula flights
Manchester to San Pedro Sula flights
Newcastle upon Tyne to Panama City flights
Manchester to San Salvador flights
Birmingham to San José flights
Manchester to Liberia flights
Birmingham to Panama City flights
Edinburgh to Panama City flights
Edinburgh to Liberia flights
Stansted to Managua flights
Newcastle upon Tyne to San José flights
Manchester to Philip S.W.Goldson flights
Manchester to Managua flights
Edinburgh to Guatemala City flights
Bristol to Guatemala City flights

Top 8 airlines flying from London to Panama

Discover the top 8 airlines that operate flights from London to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 23 February 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest£527Average£584FlexibilityNo cancel feeOn-time71%
Search Avianca flights
LufthansaCheapest£546Average£625FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
KLMCheapest£558Average£744FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air EuropaCheapest£572Average£639FlexibilityNo cancel feeOn-time83%
Search Air Europa flights
Air FranceCheapest£578Average£704FlexibilityNo cancel feeOn-time77%
Search Air France flights
United AirlinesCheapest£587Average£712FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
British AirwaysCheapest£628Average£803FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Turkish AirlinesCheapest£670Average£842FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from London to Panama?

When you search for this flight from London to Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from London to Panama?

Cheapflights simply makes it quick and affordable to book flights from London to Panama by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from London to Panama with no change fees?

Yes! Cheapflights helps users easily find flights from London to Panama with no change fees.

Can Cheapflights notify me if prices for flights from London to Panama become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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