Cheap flights from Mexico City to San Francisco from £149
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
Cheapflights Tip: The best prices from Mexico City Benito Juarez to San Francisco are usually found in August or March, booked 52 days in advance, depart on a Monday or Tuesday and return on a Tuesday
Find flight deals from Mexico City to San Francisco
Cheapest flights from Mexico City to San FranciscoExplore the most affordable flight options available from Mexico City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 October 2025.
Explore the most affordable flight options available from Mexico City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 October 2025.
Cheap flight deals from Mexico City to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 October 2025.
Cheapflights Fare Finder
Use the filters below to find and compare flights from Mexico City to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Fri 30/1
08:45-11:51
Nonstop5h 06m
San Francisco
Mon 2/2
22:30-04:55
Nonstop4h 25m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Thu 6/11
06:10-09:09
Nonstop4h 59m
San Francisco
Mon 10/11
22:49-05:05
Nonstop4h 16m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Tue 17/2
08:45-11:51
Nonstop5h 06m
San Francisco
Mon 23/2
22:30-04:55
Nonstop4h 25m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Sun 7/12
06:10-09:09
Nonstop4h 59m
San Francisco
Tue 30/12
22:49-05:05
Nonstop4h 16m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Thu 27/11
06:10-09:09
Nonstop4h 59m
San Francisco
Sun 30/11
22:49-05:05
Nonstop4h 16m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Thu 25/12
06:10-09:09
Nonstop4h 59m
San Francisco
Mon 12/1
22:49-05:05
Nonstop4h 16m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Tue 11/11
06:10-09:09
Nonstop4h 59m
San Francisco
Sun 16/11
22:49-05:05
Nonstop4h 16m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Sun 16/11
06:10-09:09
Nonstop4h 59m
San Francisco
Tue 18/11
22:49-05:05
Nonstop4h 16m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Fri 6/3
08:45-11:51
Nonstop5h 06m
San Francisco
Sun 8/3
08:55-23:55
1 stop14h 00m
Mexico CitySan Francisco
MEX - SFO
MEXSFO
Mexico City Benito Juarez
Mon 9/2
08:45-11:51
Nonstop5h 06m
San Francisco
Fri 13/2
08:55-19:35
1 stop8h 40m
Best time to book a flight from Mexico City to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mexico City with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Mexico City to San Francisco
How far ahead should I book a flight from Mexico City to San Francisco?
The best time to book flights from Mexico City to San Francisco is 52 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Mexico City to San Francisco?
Currently, February is the cheapest month in which you can book a flight from Mexico City to San Francisco (average of £88). Flying from Mexico City to San Francisco in December is currently the most expensive (average of £157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MEX to SFO?
When flying from Mexico City to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Mexico City to San Francisco delayed?
About 8% of weekly flights between Mexico City and San Francisco have experienced delays in the past year, with the average delay time being 160 minutes.
What is the most punctual flight time for Mexico City to San Francisco flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Mexico City to San Francisco flights?
Over the past year, Aeromexico have had the lowest number of delays on this route, with just 4% of flights being delayed.
Related info for your journey
Find useful and relevant information for your journey from Mexico City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Mexico City to San Francisco
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Yes! Cheapflights helps users easily find flights from Mexico City to San Francisco with no change fees.
Can Cheapflights notify me if prices for flights from Mexico City to San Francisco become cheaper?
Not ready to book yet? You can track prices for flights from Mexico City to San Francisco on Cheapflights with our Price Alert feature and get notified when better prices are available.