Cheap flights from Brussels Bruxelles-National Airport to San Francisco from £371
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
Cheap flight deals from Bruxelles-National to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 October 2025.
Find flight deals from Bruxelles-National to San Francisco
Cheapest flights from Bruxelles-National to San FranciscoExplore the most affordable flight options available from Bruxelles-National to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2025.
Explore the most affordable flight options available from Bruxelles-National to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2025.
Cheapflights Fare Finder
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Fri 21/11
17:55-14:45
1 stop29h 50m
San Francisco
Fri 5/12
19:10-11:00
1 stop30h 50m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Wed 11/3
20:30-15:35
1 stop27h 05m
San Francisco
Sun 15/3
17:40-19:50
1 stop18h 10m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Thu 25/12
10:20-14:35
1 stop13h 15m
San Francisco
Mon 29/12
16:40-19:50
1 stop18h 10m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Thu 12/3
19:15-15:35
1 stop28h 20m
San Francisco
Mon 16/3
17:40-09:40
1 stop32h 00m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Mon 2/3
11:50-18:45
1 stop15h 55m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Sat 14/3
11:35-19:45
1 stop16h 10m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Thu 25/12
20:35-18:37
2 stops31h 02m
BrusselsSan Francisco
BRU - SFO
BRUSFO
Brussels Bruxelles-National
Tue 30/12
06:15-11:50
1 stop14h 35m
Best time to book a flight from Bruxelles-National to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Bruxelles-National with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Brussels Bruxelles-National Airport to San Francisco
How far ahead should I book a flight from Brussels Bruxelles-National Airport to San Francisco?
The price you pay for your flight from Brussels Bruxelles-National Airport to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to San Francisco (average of £379). Flying from Brussels Bruxelles-National Airport to San Francisco in July is currently the most expensive (average of £459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from BRU to SFO?
It’s typically best to fly out from Brussels Bruxelles-National Airport to San Francisco in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying at midday, which is usually more expensive.
What’s the top stopover airport for flights from Brussels Bruxelles-National Airport to San Francisco?
Dublin (DUB) – chosen by Cheapflights users on 50% of one-stop itineraries from Brussels Bruxelles-National Airport to San Francisco on Cheapflights.
What’s the fastest stopover option from Brussels Bruxelles-National Airport to San Francisco?
Flights via Dublin (DUB) have the shortest average one-way travel time for one-stop routes: 14h 30m.
What’s the fastest stopover option from Brussels Bruxelles-National Airport to San Francisco?
Flights via Dublin (DUB) have the shortest average one-way travel time for one-stop routes: 14h 30m.
Which airport typically offers the quickest stopover for flights from Brussels Bruxelles-National Airport to San Francisco?
Flights via Zurich (ZRH) offer the fastest connection on this route, with an average stopover time of 2h 18m.
Related info for your journey
Find useful and relevant information for your journey from Bruxelles-National to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Travelling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsBrowse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Bruxelles-National to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Fly with Cheapflights
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Bruxelles-National to San Francisco?
Cheapflights helps you search for flights from Bruxelles-National to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.
Why should you use Cheapflights to find cheap flight tickets from Bruxelles-National to San Francisco?
Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Bruxelles-National to San Francisco for you. Better yet — we are completely free to use.
Can Cheapflights find flights from Bruxelles-National to San Francisco with no change fees?
Cheapflights does show flights with no change fees to all users. To see these options for flights from Bruxelles-National to San Francisco, users can toggle the no change fees filter when performing a flight search.
Can Cheapflights notify me if prices for flights from Bruxelles-National to San Francisco become cheaper?
Not ready to book yet? You can track prices for flights from Bruxelles-National to San Francisco on Cheapflights with our Price Alert feature and get notified when better prices are available.