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Cheap flights from Manchester to Santa Ana, California from £354

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — SNA
9 Nov — 16 Nov1
1 adult
1 adult, Economy

Find flight deals from Manchester to Santa Ana

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Santa Ana
Explore the most affordable flight options available from Manchester to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 October 2025.

Wed 19/1106:25MAN - SNA
2 stops19h 53mLufthansa
Wed 3/1210:02SNA - MAN
2 stops22h 53mLufthansa
Deal found 10/10£559
Wed 19/1113:30MAN - SNA
1 stop16h 49mVirgin Atlantic
Wed 3/1209:49SNA - MAN
2 stops22h 16mVirgin Atlantic
Deal found 10/10£565
Wed 5/1106:00MAN - SNA
2 stops19h 26mMultiple Airlines
Wed 12/1106:45SNA - MAN
2 stops19h 35mMultiple Airlines
Deal found 9/10£586
Wed 19/1113:30MAN - SNA
1 stop16h 49mDelta
Wed 3/1207:00SNA - MAN
2 stops19h 10mDelta
Deal found 10/10£587
Sun 23/1106:00MAN - SNA
2 stops48h 13mUnited Airlines
Sun 30/1118:41SNA - MAN
2 stops38h 19mUnited Airlines
Deal found 9/10£600
Wed 5/1106:00MAN - SNA
2 stops19h 26mUnited Airlines
Wed 12/1118:41SNA - MAN
3 stops30h 04mUnited Airlines
Deal found 9/10£603
Wed 5/1113:30MAN - SNA
1 stop16h 58mVirgin Atlantic
Wed 12/1108:00SNA - MAN
2 stops18h 10mVirgin Atlantic
Deal found 9/10£607
Wed 29/1006:10MAN - SNA
2 stops20h 53mBritish Airways
Wed 12/1111:42SNA - MAN
2 stops15h 13mBritish Airways
Deal found 9/10£612
Sun 30/1117:45MAN - SNA
2 stops49h 40mMultiple Airlines
Thu 25/1219:05SNA - MAN
2 stops20h 15mMultiple Airlines
Deal found 9/10£616

Cheap flight deals from Manchester to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 October 2025.

Round-trip from

£568

One-way from

£354

Popular in

July

Cheapest in

March

Average price

£685
Virgin Atlantic
  • Virgin Atlantic
  • 19/11-3/12
  • 3 total stops
  • 33h 10m total
  • Manchester to Santa Ana
Search Deals
Virgin Atlantic
  • Virgin Atlantic
  • 10/12
  • 1 total stop
  • 16h 50m total
  • Manchester to Santa Ana
Search Deals
Highest demand for flights based on searches. 17% potential increase in price (£115 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£30 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 October 2025.
Use the filters below to find and compare flights from Manchester to Santa Ana that are best for you.

Fly from

Manchester

Fly to

Santa Ana

Route

Depart

Return

Price

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 19/11

13:30-22:19

1 stop16h 49m

Santa Ana J. Wayne/Orange Cnty

Wed 3/12

09:49-10:10

2 stops16h 21m

£568

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 5/11

06:00-17:26

2 stops19h 26m

Santa Ana J. Wayne/Orange Cnty

Wed 12/11

06:45-10:20

2 stops19h 35m

£586

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 19/11

13:30-22:19

1 stop16h 49m

Santa Ana J. Wayne/Orange Cnty

Wed 3/12

07:00-10:10

2 stops19h 10m

£587

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Sun 23/11

06:00-22:13

2 stops48h 13m

Santa Ana J. Wayne/Orange Cnty

Sun 30/11

18:41-17:00

2 stops38h 19m

£600

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 5/11

06:00-17:26

2 stops19h 26m

Santa Ana J. Wayne/Orange Cnty

Wed 12/11

18:41-08:45

3 stops30h 04m

£603

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 5/11

13:30-22:28

1 stop16h 58m

Santa Ana J. Wayne/Orange Cnty

Wed 12/11

08:00-10:10

2 stops18h 10m

£607

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Sat 24/1

09:50-22:01

2 stops20h 11m

Santa Ana J. Wayne/Orange Cnty

Tue 3/2

11:42-11:25

2 stops15h 43m

£614

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Sun 30/11

17:45-11:25

2 stops49h 40m

Santa Ana J. Wayne/Orange Cnty

Thu 25/12

19:05-23:20

2 stops20h 15m

£616

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Tue 3/2

09:40-22:01

2 stops20h 21m

Santa Ana J. Wayne/Orange Cnty

Fri 6/2

11:42-11:55

2 stops16h 13m

£618

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 7/1

18:30-16:10

2 stops29h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 17/1

15:15-16:25

2 stops17h 10m

£647

Flights are sorted by cheapest return flights first.

Deals found on 10/10

Showing 1-10 of 22 results
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Best time to book a flight from Manchester to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Santa Ana

What is the cheapest month to book a flight from Manchester to Santa Ana, California?

Currently, February is the cheapest month in which you can book a flight from Manchester to Santa Ana, California (average of £359). Flying from Manchester to Santa Ana, California in July is currently the most expensive (average of £502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated 10 October 2025.
Read reviews from past customers who have flown with Virgin Atlantic and British Airways from Manchester to Santa Ana. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.4
Good
665 reviews
Check prices

Boarding

7.7

Crew

8.1

Entertainment

7.5

Comfort

7.3

Food

6.9

Overall

7.4

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.4
Good
665 reviews
Virgin Atlantic
7.4
Good
665 reviews
Check prices

Boarding

7.7

Crew

8.1

Entertainment

7.5

Comfort

7.3

Food

6.9

Overall

7.4

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,449 reviews
Virgin Atlantic
7.4
Good
665 reviews
Check prices

Boarding

7.7

Crew

8.1

Entertainment

7.5

Comfort

7.3

Food

6.9

Overall

7.4

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from Manchester to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Santa Ana, California?

    For as low as £568, Virgin Atlantic can have you in Santa Ana, California from Manchester in 16h 49m. Airlines will cover a distance of 5295 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines flying from Manchester to Santa Ana, California round-trip?

    British Airways, at £450, was found to be the cheapest airline from Manchester to Santa Ana, California. An alternate airline flying to your destination would be Virgin Atlantic. British Airways is 36% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Manchester to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Manchester to Santa Ana flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Santa Ana.

  • Can I find deals for business class flights from Manchester to Santa Ana?

    Yes. Cheapflights offers flight deals from Manchester to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Santa Ana, California?

    Currently, February is the cheapest month in which you can book a flight from Manchester to Santa Ana, California (average of £359). Flying from Manchester to Santa Ana, California in July is currently the most expensive (average of £502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Santa Ana

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Top 2 airlines flying from Manchester to Santa Ana

Discover the top 2 airlines that operate flights from Manchester to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 October 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£450Average£550FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£507Average£734FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Santa Ana?

Deals for Manchester to Santa Ana flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Santa Ana?

Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to Santa Ana for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Manchester to Santa Ana with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Santa Ana with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Santa Ana become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Santa Ana flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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