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Cheap flights from Manchester to Santa Ana from £401

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — SNA
26 Mar — 2 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Santa Ana

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Santa Ana
Explore the most affordable flight options available from Manchester to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 February 2026.

Tue 14/407:00
MAN
-
SNA
2 stops18h 33m
Lufthansa
Tue 28/416:24
SNA
-
MAN
2 stops17h 11m
Lufthansa
Deal found 21/2£586
Mon 2/1109:40
MAN
-
SNA
2 stops21h 10m
British Airways
Sun 8/1116:25
SNA
-
MAN
2 stops19h 45m
British Airways
Deal found 21/2£591
Tue 17/306:00
MAN
-
SNA
2 stops21h 50m
United Airlines
Mon 23/306:45
SNA
-
MAN
2 stops19h 00m
United Airlines
Deal found 21/2£604
Mon 9/306:00
MAN
-
SNA
2 stops23h 15m
United Airlines
Wed 18/306:46
SNA
-
MAN
2 stops20h 34m
United Airlines
Deal found 22/2£606
Mon 2/1108:55
MAN
-
SNA
2 stops19h 08m
American Airlines
Sun 8/1110:40
SNA
-
MAN
2 stops16h 15m
American Airlines
Deal found 21/2£637
Tue 14/420:05
MAN
-
SNA
2 stops30h 24m
British Airways
Wed 29/416:23
SNA
-
MAN
2 stops18h 42m
British Airways
Deal found 22/2£638
Sat 18/407:00
MAN
-
SNA
2 stops19h 16m
Lufthansa
Sat 25/416:39
SNA
-
MAN
2 stops16h 41m
Lufthansa
Deal found 21/2£657
Mon 2/1120:35
MAN
-
SNA
2 stops32h 02m
Virgin Atlantic
Sun 8/1107:45
SNA
-
MAN
1 stop15h 10m
Virgin Atlantic
Deal found 21/2£661
Sat 11/406:05
MAN
-
SNA
2 stops35h 39m
United Airlines
Sat 25/414:25
SNA
-
MAN
2 stops18h 55m
United Airlines
Deal found 23/2£670
Wed 26/810:40
MAN
-
SNA
1 stop19h 44m
KLM
Sun 13/912:20
SNA
-
MAN
1 stop36h 30m
KLM
Deal found 21/2£703
Tue 7/405:55
MAN
-
SNA
2 stops19h 38m
United Airlines
Tue 14/410:50
SNA
-
MAN
2 stops22h 45m
United Airlines
Deal found 21/2£720
Wed 8/406:05
MAN
-
SNA
2 stops19h 18m
United Airlines
Wed 15/412:15
SNA
-
MAN
2 stops38h 10m
United Airlines
Deal found 22/2£721

Find flight deals from Manchester to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 24 February 2026.

Round-trip from

£586

One-way from

£401

Popular in

December

Cheapest in

March

Average price

£789
Lufthansa
  • Lufthansa
  • 14/4-28/4
  • 4 total stops
  • 35h 44m total
  • Manchester to Santa Ana
Search Deals
Lufthansa
  • Lufthansa
  • 6/5
  • 2 total stops
  • 18h 28m total
  • Manchester to Santa Ana
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£52 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease (£38 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 February 2026.
Use the filters below to find and compare flights from Manchester to Santa Ana that are best for you.

Fly from

Manchester

Fly to

Santa Ana

Route

Depart

Return

Price

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Mon 9/3

06:00-22:15

2 stops23h 15m

Santa Ana J. Wayne/Orange Cnty

Wed 18/3

06:46-10:20

2 stops20h 34m

£606

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Sat 11/4

06:05-09:44

2 stops35h 39m

Santa Ana J. Wayne/Orange Cnty

Sat 25/4

14:25-17:20

2 stops18h 55m

£670

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Tue 7/4

05:55-17:33

2 stops19h 38m

Santa Ana J. Wayne/Orange Cnty

Tue 14/4

10:50-17:35

2 stops22h 45m

£720

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Wed 8/4

06:05-17:23

2 stops19h 18m

Santa Ana J. Wayne/Orange Cnty

Wed 15/4

12:15-10:25

2 stops38h 10m

£721

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Thu 9/4

05:55-17:23

2 stops19h 28m

Santa Ana J. Wayne/Orange Cnty

Thu 16/4

07:00-17:20

2 stops26h 20m

£751

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Fri 10/7

07:55-19:37

2 stops19h 42m

Santa Ana J. Wayne/Orange Cnty

Mon 20/7

11:28-11:30

2 stops16h 02m

£805

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Thu 26/3

09:05-18:23

2 stops40h 18m

Santa Ana J. Wayne/Orange Cnty

Sun 19/4

21:20-14:00

2 stops32h 40m

£893

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Fri 27/3

06:00-21:55

2 stops22h 55m

Santa Ana J. Wayne/Orange Cnty

Sat 18/4

09:54-11:00

2 stops41h 06m

£939

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Thu 26/3

13:30-11:24

1 stop28h 54m

Santa Ana J. Wayne/Orange Cnty

Thu 16/4

09:54-20:05

2 stops26h 11m

£956

ManchesterSanta Ana

MAN - SNA

MANSNA

Manchester

Sun 5/4

11:10-17:23

2 stops38h 13m

Santa Ana J. Wayne/Orange Cnty

Sun 12/4

18:28-17:10

2 stops38h 42m

£984

Flights are sorted by cheapest return flights first.

Deals found on 21/2

Showing 1-10 of 19 results
1
2

Best time to book a flight from Manchester to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Santa Ana

What is the cheapest month to book a flight from Manchester to Santa Ana?

Currently, February is the cheapest month in which you can book a flight from Manchester to Santa Ana (average of £346). Flying from Manchester to Santa Ana in July is currently the most expensive (average of £478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated 24 February 2026.
Read reviews from past customers who have flown with Virgin Atlantic and British Airways from Manchester to Santa Ana. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
679 reviews
Check prices

Entertainment

7.6

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
679 reviews
Virgin Atlantic
7.5
Good
679 reviews
Check prices

Entertainment

7.6

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,762 reviews
Virgin Atlantic
7.5
Good
679 reviews
Check prices

Entertainment

7.6

Food

6.9

Overall

7.5

Comfort

7.3

Crew

8.2

Boarding

7.7

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from Manchester to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Santa Ana?

    There are many flights that can get you from Manchester to Santa Ana in 23h 15m. Fly via United Airlines to get the fastest option. The distance from Manchester to Santa Ana is about 5295 mi.

  • What are the cheapest airlines flying from Manchester to Santa Ana round-trip?

    British Airways, at £446, was found to be the cheapest airline from Manchester to Santa Ana. An alternate airline flying to your destination would be Virgin Atlantic. British Airways is 40% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Manchester to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Manchester to Santa Ana flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Santa Ana.

  • Can I find deals for business class flights from Manchester to Santa Ana?

    Yes. Cheapflights offers flight deals from Manchester to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Santa Ana?

    Currently, February is the cheapest month in which you can book a flight from Manchester to Santa Ana (average of £346). Flying from Manchester to Santa Ana in July is currently the most expensive (average of £478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Manchester to Santa Ana

Discover the top 2 airlines that operate flights from Manchester to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 February 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£446Average£537FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£500Average£726FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Santa Ana?

Deals for Manchester to Santa Ana flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Santa Ana?

Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to Santa Ana for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Manchester to Santa Ana with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Santa Ana with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Santa Ana become cheaper?

Yes, Cheapflights offers price alerts on Manchester to Santa Ana flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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