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Cheap flights from Cancún to Santiago from £220

CUN — SCL
31 Oct — 7 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cancún to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Cancún to Santiago

Thu 5/1107:11 -
1 stop15h 08m
Wed 25/1105:07 -
1 stop19h 00m
Deal found 28/9£501
Thu 5/1107:11 -
1 stop15h 08m
Sat 14/1101:22 -
1 stop22h 45m
Deal found 27/9£518
Thu 1/1013:54 -
1 stop14h 16m
Sun 4/1012:23 -
1 stop23h 37m
Deal found 30/9£535
Thu 24/1207:05 -
1 stop14h 30m
Mon 11/101:12 -
1 stop22h 55m
Deal found 30/9£544
Sat 19/1207:05 -
1 stop15h 13m
Tue 29/1203:48 -
1 stop20h 19m
Deal found 30/9£565
Sun 13/1207:05 -
1 stop18h 38m
Sun 10/105:13 -
1 stop18h 54m
Deal found 28/9£578
Sat 19/1207:05 -
1 stop15h 13m
Sun 3/101:12 -
1 stop22h 55m
Deal found 1/10£594
Sun 20/1207:05 -
1 stop15h 13m
Sun 10/105:13 -
1 stop18h 54m
Deal found 29/9£629
Wed 9/1216:31 -
1 stop12h 07m
Fri 8/105:00 -
1 stop12h 41m
Deal found 28/9£647
Tue 15/1212:35 -
1 stop13h 00m
Thu 7/110:00 -
1 stop13h 10m
Deal found 28/9£660
Tue 15/1212:35 -
1 stop13h 00m
Sat 9/109:25 -
1 stop30h 22m
Deal found 28/9£697
Tue 15/1212:35 -
1 stop13h 00m
Mon 11/106:00 -
1 stop12h 51m
Deal found 28/9£708

Find flight deals from Cancún to Santiago

Round-trip from

£501

One-way from

£220

Popular in

December

Cheapest in

September

Average price

£496
Copa Airlines
  • Copa Airlines
  • 5/11-25/11
  • 2 total stops
  • 34h 08m total
  • Cancún to Santiago
Search Deals
31/12-31/12
  • 31/12-31/12
  • 2 total stops
  • 29h 59m total
  • Cancún to Santiago
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (£27 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£10 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Cancún to Santiago that are best for you.

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Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Wed 24/2

16:31-06:38

1 stop12h 07m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£236

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Tue 1/12

06:49-15:00

2 stops30h 11m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£241

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Tue 10/11

07:11-03:38

1 stop18h 27m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£243

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Sun 20/12

07:05-23:35

1 stop14h 30m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£243

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Thu 22/10

06:04-06:25

2 stops22h 21m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£243

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Mon 14/12

07:05-02:48

1 stop17h 43m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£243

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Sun 13/12

07:05-03:43

1 stop18h 38m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£256

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Sat 13/3

20:50-11:41

3 stops36h 51m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£308

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Fri 26/3

06:06-11:41

3 stops27h 35m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£324

CancúnSantiago

CUN Cancun - SCL Santiago Arturo Merino Benitez

CUNSCL

Cancun

Thu 5/11

07:11-00:19

1 stop15h 08m

Santiago Arturo Merino Benitez

Wed 25/11

05:07-22:07

1 stop19h 00m

£501

Flights are sorted by cheapest return flights first.

Deals found on 27/9

Showing 1-10 of 19 resultsSorted by cheapest first
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Best time to book a flight from Cancún to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cancún with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Cancún to Santiago

How far ahead should I book a flight from Cancún to Santiago?

To ensure you get the cheapest price possible for a flight from Cancún to Santiago, you should look to book at least 16 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cancún to Santiago?

Currently, September is the cheapest month in which you can book a flight from Cancún to Santiago (average of £386). Flying from Cancún to Santiago in December is currently the most expensive (average of £648). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Cancún to Santiago?

Airfare is typical for this route at the moment.

Cancún to Santiago flights typically cost between £418 and £581 in November.
The cheapest return price found within the last 5 days was £501 on Copa Airlines (5 Nov–25 Nov).

Related info for your journey

  • How long is the flight from Cancún to Santiago?

    Departing from Cancún to Santiago will take you 15h 08m. There are 3905 mi between Cancún and Santiago.

  • Can I find deals for flights from Cancún to Santiago that include hotel bookings?

    Yes. In addition to deals on Cancún to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Cancún to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cancún to Santiago.

  • Can I find deals for business class flights from Cancún to Santiago?

    Yes. Cheapflights offers flight deals from Cancún to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cancún to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Cancún to Santiago (average of £386). Flying from Cancún to Santiago in December is currently the most expensive (average of £648). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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Complete your trip

Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Lastarria car hire

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How does Cheapflights help users find flights from Cancún to Santiago?

When you search for this flight from Cancún to Santiago, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Cancún to Santiago?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Santiago from Cancún.

Can Cheapflights find flights from Cancún to Santiago with no change fees?

Yes, we can. To see specific flights from Cancún to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Cancún to Santiago become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Santiago from Cancún today and book when prices fit your budget.

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