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Cheap flights from Guatemala City to Santiago from £346

GUA — SCL
22 Oct — 29 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Guatemala City to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Guatemala City to Santiago

Sun 1/1107:16 -
1 stop14h 03m
Sat 7/1112:15 -
2 stops12h 21m
Deal found 22/9£380
Tue 27/1006:24 -
2 stops17h 22m
Tue 17/1103:48 -
2 stops20h 48m
Deal found 22/9£418
Mon 2/1110:41 -
1 stop13h 57m
Mon 14/1203:48 -
1 stop11h 03m
Deal found 21/9£430
Tue 13/1006:20 -
1 stop15h 00m
Wed 21/1016:20 -
1 stop12h 20m
Deal found 21/9£439
Mon 5/1002:25 -
1 stop18h 14m
Tue 13/1012:23 -
2 stops12h 13m
Deal found 17/9£455
Wed 11/1106:19 -
2 stops14h 17m
Mon 16/1112:15 -
2 stops12h 21m
Deal found 21/9£461
Mon 5/1004:20 -
1 stop20h 36m
Sun 11/1001:07 -
1 stop11h 26m
Deal found 21/9£468
Thu 19/1106:19 -
2 stops15h 00m
Thu 26/1112:15 -
2 stops12h 21m
Deal found 21/9£475

Find flight deals from Guatemala City to Santiago

Round-trip from

£380

One-way from

£346

Popular in

October

Cheapest in

April

Average price

£418
Copa Airlines
  • Copa Airlines
  • 29/10-10/11
  • 4 total stops
  • 35h 46m total
  • Guatemala City to Santiago
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Arajet
  • Arajet
  • 21/1-31/12
  • 1 total stop
  • 12h 59m total
  • Guatemala City to Santiago
Search Deals
Highest demand for flights based on searches. 0% potential increase in price (£0 potential increase over avg. return price).
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Cheapest flight prices on average. 0% potential price decrease (£3 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Guatemala City to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Thu 21/1

11:36-03:35

1 stop12h 59m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£346

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Sat 7/11

06:19-23:36

2 stops14h 17m

Santiago Arturo Merino Benitez

Mon 23/11

12:15-08:46

1 stop23h 31m

£418

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Tue 6/10

04:20-00:22

1 stop17h 02m

Santiago Arturo Merino Benitez

Tue 13/10

12:23-21:36

2 stops12h 13m

£455

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Sat 5/12

06:19-23:35

2 stops14h 16m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£461

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Fri 1/1

06:24-23:40

2 stops14h 16m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£461

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Sun 8/11

06:24-23:36

2 stops14h 12m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£461

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Mon 26/10

06:24-03:42

2 stops18h 18m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£461

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Sun 10/1

06:24-00:23

2 stops14h 59m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-21:00

Nonstop0h 00m

£461

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Mon 7/12

10:42-02:48

1 stop13h 06m

Santiago Arturo Merino Benitez

Thu 10/12

01:07-09:40

1 stop11h 33m

£475

Guatemala CitySantiago

GUA Guatemala City La Aurora - SCL Santiago Arturo Merino Benitez

GUASCL

Guatemala City La Aurora

Fri 4/12

06:19-00:18

2 stops14h 59m

Santiago Arturo Merino Benitez

Mon 7/12

01:07-08:46

1 stop10h 39m

£475

Flights are sorted by cheapest return flights first.

Deals found on 20/9

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Guatemala City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Guatemala City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to Santiago

How far ahead should I book a flight from Guatemala City to Santiago?

To ensure you get the cheapest price possible for a flight from Guatemala City to Santiago, you should look to book at least 75 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guatemala City to Santiago?

Currently, April is the cheapest month in which you can book a flight from Guatemala City to Santiago (average of £413). Flying from Guatemala City to Santiago in October is currently the most expensive (average of £469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Guatemala City to Santiago?

Airfare is typical for this route at the moment.

Guatemala City to Santiago flights typically cost between £360 and £490 in November.
The cheapest return price found within the last 5 days was £380 on Copa Airlines (1 Nov–7 Nov).

Related info for your journey

  • How long is the flight from Guatemala City to Santiago?

    For as low as £380, Copa Airlines can have you in Santiago from Guatemala City in 15h. Airlines will cover a distance of 3559 mi.

  • Can I find deals for flights from Guatemala City to Santiago that include hotel bookings?

    Yes. In addition to deals on Guatemala City to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Guatemala City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to Santiago.

  • Can I find deals for business class flights from Guatemala City to Santiago?

    Yes. Cheapflights offers flight deals from Guatemala City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guatemala City to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Guatemala City to Santiago (average of £413). Flying from Guatemala City to Santiago in October is currently the most expensive (average of £469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

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Viña del Mar

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Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Balmaceda car hire
Lastarria car hire

Fly with Cheapflights

How does Cheapflights help users find flights from Guatemala City to Santiago?

Cheapflights makes it easy to find Guatemala City to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Guatemala City to Santiago?

Cheapflights simply makes it quick and affordable to book flights from Guatemala City to Santiago by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Guatemala City to Santiago with no change fees?

Certainly. Search results for flights to Santiago from Guatemala City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Guatemala City to Santiago become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Santiago from Guatemala City today and book when prices fit your budget.

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