What day of the week experiences the fewest flight delays on this route?

Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.

How often are flights from Mexico City to Santiago delayed?

About 11% of weekly flights between Mexico City and Santiago have experienced delays in the past year, with the average delay time being 106 minutes.

What is the most punctual flight time for Mexico City to Santiago flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

Which airline has the best punctuality record on Mexico City to Santiago flights?

Over the past year, LATAM Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.

How popular is this Mexico City to Santiago flight route?

Within the past month, 1 users have taken a look at flights from Mexico City Benito Juarez to Santiago Arturo Merino Benitez.

How long is the flight from Mexico City to Santiago?

Airlines like Copa Airlines fly from Mexico City to Santiago in about 19h 19m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 4096 mi.

Weekly flight availability from Mexico City to Santiago

The most flights from MEX to SCL are scheduled on a Monday (2 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 inches per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

What are the most reliable airlines from Mexico City to Santiago?

Consider Aeromexico (100%), LATAM Airlines (93%) or Wamos Air (93%) when booking your flight. These represent the most reliable airlines when flying from Mexico City to Santiago.

Can I find deals for flights from Mexico City to Santiago that include hotel bookings?

Yes. In addition to deals on Mexico City to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Mexico City to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santiago.

Can I find deals for business class flights from Mexico City to Santiago?

Yes. Cheapflights offers flight deals from Mexico City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£197+ Flights from Mexico City to Santiago

Cheap flight deals from Mexico City to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Mexico City to Santiago
Explore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 December 2025.

Wed 24/1213:10MEX - SCL

1 stop11h 33mCopa Airlines

Tue 30/1203:23SCL - MEX

1 stop14h 07mCopa Airlines

Deal found 15/12£390

Wed 24/1213:10MEX - SCL

1 stop13h 51mCopa Airlines

Tue 10/305:21SCL - MEX

1 stop21h 54mCopa Airlines

Deal found 14/12£396

Fri 19/1201:20MEX - SCL

1 stop19h 21mCopa Airlines

Tue 30/1212:20SCL - MEX

1 stop14h 55mCopa Airlines

Deal found 13/12£515

Wed 24/1209:25MEX - SCL

1 stop15h 18mCopa Airlines

Sat 10/105:20SCL - MEX

1 stop21h 55mCopa Airlines

Deal found 12/12£542

Mon 22/1209:25MEX - SCL

1 stop11h 16mCopa Airlines

Mon 29/1205:12SCL - MEX

1 stop22h 03mCopa Airlines

Deal found 15/12£558

Tue 30/1201:20MEX - SCL

1 stop20h 04mCopa Airlines

Thu 8/105:20SCL - MEX

1 stop21h 55mCopa Airlines

Deal found 14/12£562

Tue 16/1202:00MEX - SCL

1 stop19h 24mCopa Airlines

Fri 19/1212:20SCL - MEX

1 stop12h 45mCopa Airlines

Deal found 13/12£584

Wed 17/1215:30MEX - SCL

1 stop11h 31mCopa Airlines

Sat 31/105:44SCL - MEX

1 stop16h 36mCopa Airlines

Deal found 15/12£605

Tue 23/1209:25MEX - SCL

1 stop15h 18mCopa Airlines

Sat 17/105:20SCL - MEX

1 stop19h 45mCopa Airlines

Deal found 15/12£612

Fri 26/1202:00MEX - SCL

1 stop19h 24mCopa Airlines

Wed 7/105:20SCL - MEX

1 stop21h 55mCopa Airlines

Deal found 14/12£616

Wed 17/1201:20MEX - SCL

1 stop20h 04mCopa Airlines

Wed 31/1201:46SCL - MEX

1 stop13h 24mCopa Airlines

Deal found 14/12£621

Best flights from Mexico City to Santiago
Discover carefully curated flight deals from Mexico City to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 16 December 2025.

Sun 18/105:55MEX - SCL

1 stop19h 19mCopa Airlines

Sat 31/105:44SCL - MEX

1 stop19h 21mCopa Airlines

Deal found 15/12£427

Sat 10/117:30MEX - SCL

1 stop25h 30mMultiple Airlines

Sat 17/109:10SCL - MEX

Nonstop8h 40mMultiple Airlines

Deal found 13/12£431

Sat 24/101:20MEX - SCL

1 stop16h 00mCopa Airlines

Wed 4/205:20SCL - MEX

1 stop12h 10mCopa Airlines

Deal found 14/12£442

Sat 24/109:25MEX - SCL

1 stop11h 18mCopa Airlines

Sat 7/205:44SCL - MEX

1 stop19h 21mCopa Airlines

Deal found 14/12£461

Sat 3/109:25MEX - SCL

1 stop11h 18mCopa Airlines

Sun 1/212:28SCL - MEX

1 stop14h 47mCopa Airlines

Deal found 13/12£508

Mon 26/101:20MEX - SCL

1 stop16h 00mCopa Airlines

Sat 31/103:34SCL - MEX

1 stop18h 46mCopa Airlines

Deal found 13/12£523

Sat 3/109:25MEX - SCL

1 stop12h 07mCopa Airlines

Tue 20/105:20SCL - MEX

1 stop19h 45mCopa Airlines

Deal found 14/12£542

Tue 6/105:55MEX - SCL

1 stop21h 05mCopa Airlines

Wed 14/112:28SCL - MEX

1 stop15h 32mCopa Airlines

Deal found 13/12£542

Fri 9/109:25MEX - SCL

1 stop12h 07mCopa Airlines

Tue 13/105:20SCL - MEX

1 stop21h 55mCopa Airlines

Deal found 12/12£542

Last-minute flights from Mexico City to Santiago
Discover last-minute flight deals from Mexico City to Santiago. Data last updated 16 December 2025 and is based on user searches.

Fri 19/1201:20MEX - SCL

1 stop19h 21mCopa Airlines

Tue 30/1212:20SCL - MEX

1 stop14h 55mCopa Airlines

Deal found 13/12£515

Wed 24/1213:10MEX - SCL

1 stop11h 33mCopa Airlines

Tue 30/1203:23SCL - MEX

1 stop14h 07mCopa Airlines

Deal found 15/12£390

Wed 24/1213:10MEX - SCL

1 stop13h 51mCopa Airlines

Tue 10/305:21SCL - MEX

1 stop21h 54mCopa Airlines

Deal found 14/12£396

Fri 2/101:20MEX - SCL

1 stop19h 23mCopa Airlines

Sun 1/205:44SCL - MEX

1 stop21h 31mCopa Airlines

Deal found 15/12£508

Sat 3/105:55MEX - SCL

1 stop14h 48mCopa Airlines

Tue 3/212:28SCL - MEX

1 stop14h 47mCopa Airlines

Deal found 14/12£466

Thu 8/118:50MEX - SCL

1 stop24h 10mMultiple Airlines

Thu 15/108:50SCL - MEX

1 stop32h 00mMultiple Airlines

Deal found 12/12£437

Fri 9/105:55MEX - SCL

1 stop18h 22mCopa Airlines

Sat 24/105:44SCL - MEX

1 stop21h 31mCopa Airlines

Deal found 15/12£411

Sat 10/117:30MEX - SCL

1 stop25h 30mMultiple Airlines

Sat 17/109:10SCL - MEX

Nonstop8h 40mMultiple Airlines

Deal found 13/12£431

Sat 10/119:55MEX - SCL

1 stop23h 05mMultiple Airlines

Tue 20/109:10SCL - MEX

Nonstop8h 40mMultiple Airlines

Deal found 13/12£502

Sun 18/105:55MEX - SCL

1 stop19h 19mCopa Airlines

Sat 31/105:44SCL - MEX

1 stop19h 21mCopa Airlines

Deal found 15/12£427

Sat 24/102:00MEX - SCL

1 stop18h 43mCopa Airlines

Wed 4/205:44SCL - MEX

1 stop21h 31mCopa Airlines

Deal found 15/12£442

Sat 24/109:25MEX - SCL

1 stop11h 18mCopa Airlines

Sat 7/205:44SCL - MEX

1 stop19h 21mCopa Airlines

Deal found 14/12£461

One-way flights from Mexico City to Santiago
Search for one-way flight options from Mexico City to Santiago. Find affordable one-way fares based on user searches. Data last updated 16 December 2025.

Sat 3/101:20MEX - SCL

1 stop20h 12mCopa Airlines

Deal found 15/12£197

Thu 8/118:50MEX - SCL

2 stops17h 40mMultiple Airlines

Deal found 15/12£199

Wed 21/109:25MEX - SCL

1 stop15h 49mCopa Airlines

Deal found 13/12£213

Sun 11/117:30MEX - SCL

2 stops17h 35mMultiple Airlines

Deal found 15/12£238

Mon 12/116:30MEX - SCL

2 stops18h 35mMultiple Airlines

Deal found 14/12£277

Fri 19/1202:00MEX - SCL

1 stop15h 21mCopa Airlines

Deal found 15/12£354

Sun 18/104:00MEX - SCL

2 stops17h 30mAvianca

Deal found 15/12£373

Sun 18/116:50MEX - SCL

2 stops28h 40mAvianca

Deal found 15/12£386

Sat 27/1213:10MEX - SCL

1 stop13h 51mCopa Airlines

Deal found 15/12£574

Fri 26/1210:05MEX - SCL

1 stop19h 45mUnited Airlines

Deal found 14/12£899

Tue 23/1217:00MEX - SCL

3 stops42h 55mQantas Airways

Deal found 13/12£2,194

Find flight deals from Mexico City to Santiago

Round-trip from	£411
One-way from	£197
Popular in	February
Cheapest in	May
Average price	£520

Copa Airlines
9/1-24/1
2 total stops
39h 53m total
Mexico City to Santiago

Search Deals

Copa Airlines
3/1
1 total stop
20h 12m total
Mexico City to Santiago

Search Deals

Highest demand for flights based on searches. 8% potential increase in price (£31 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (£7 potential savings vs. average return price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sun 18/1

05:55-04:14

1 stop19h 19m

Santiago Arturo Merino Benitez

Sat 31/1

05:44-22:05

1 stop19h 21m

£427

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 10/1

17:30-22:00

1 stop25h 30m

Santiago Arturo Merino Benitez

Sat 17/1

09:10-14:50

Nonstop8h 40m

£431

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 24/1

01:20-20:20

1 stop16h 00m

Santiago Arturo Merino Benitez

Wed 4/2

05:20-14:30

1 stop12h 10m

£442

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 24/1

09:25-23:43

1 stop11h 18m

Santiago Arturo Merino Benitez

Sat 7/2

05:44-22:05

1 stop19h 21m

£461

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 3/1

09:25-23:43

1 stop11h 18m

Santiago Arturo Merino Benitez

Sun 1/2

12:28-00:15

1 stop14h 47m

£508

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Mon 26/1

01:20-20:20

1 stop16h 00m

Santiago Arturo Merino Benitez

Sat 31/1

03:34-19:20

1 stop18h 46m

£523

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 3/1

09:25-00:32

1 stop12h 07m

Santiago Arturo Merino Benitez

Tue 20/1

05:20-22:05

1 stop19h 45m

£542

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 6/1

05:55-06:00

1 stop21h 05m

Santiago Arturo Merino Benitez

Wed 14/1

12:28-01:00

1 stop15h 32m

£542

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Fri 9/1

09:25-00:32

1 stop12h 07m

Santiago Arturo Merino Benitez

Tue 13/1

05:20-00:15

1 stop21h 55m

£542

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Thu 1/1

01:20-20:20

1 stop16h 00m

£197

Flights are sorted by cheapest return flights first.

Deals found on 15/12

Showing 1-10 of 16 results

Best time to book a flight from Mexico City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mexico City with our price prediction graph.

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santiago

Prices

Airlines

Delays

How far ahead should I book a flight from Mexico City to Santiago?

Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mexico City to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mexico City to Santiago?

Currently, November is the cheapest month in which you can book a flight from Mexico City to Santiago (average of £231). Flying from Mexico City to Santiago in April is currently the most expensive (average of £353). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to SCL?

When flying from Mexico City to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

How popular is this Mexico City to Santiago flight route?
Within the past month, 1 users have taken a look at flights from Mexico City Benito Juarez to Santiago Arturo Merino Benitez.
How long is the flight from Mexico City to Santiago?
Airlines like Copa Airlines fly from Mexico City to Santiago in about 19h 19m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 4096 mi.
What are the most reliable airlines from Mexico City to Santiago?
Consider Aeromexico (100%), LATAM Airlines (93%) or Wamos Air (93%) when booking your flight. These represent the most reliable airlines when flying from Mexico City to Santiago.
Can I find deals for flights from Mexico City to Santiago that include hotel bookings?
Yes. In addition to deals on Mexico City to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Mexico City to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santiago.
Can I find deals for business class flights from Mexico City to Santiago?
Yes. Cheapflights offers flight deals from Mexico City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mexico City to Santiago?
Currently, November is the cheapest month in which you can book a flight from Mexico City to Santiago (average of £231). Flying from Mexico City to Santiago in April is currently the most expensive (average of £353). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Complete your trip

Santiago car hire

Santiago Arturo Merino Benitez Airport car hire

Punta Arenas car hire

Balmaceda car hire

Puerto Montt car hire

Lastarria car hire

Other flights to Santiago

Heathrow to Santiago flights

Santiago to Calama flights

Santiago to Buenos Aires Jorge Newbery Airport flights

Santiago to Buenos Aires Ministro Pistarini Airport flights

Santiago to Punta Arenas flights

Santiago to Puerto Montt flights

Santiago to Sao Paulo Guarulhos Intl Airport flights

Santiago to Puerto Natales flights

Santiago to Lima flights

Santiago to Bogotá flights

Santiago to Guayaquil flights

Santiago to Easter Island flights

Santiago to Balmaceda flights

Santiago to Madrid flights

Santiago to Punta Arenas flights

Santiago to Bogotá flights

Santiago to Panama City flights

Fly with Cheapflights

How does Cheapflights help users find flights from Mexico City to Santiago?

Cheapflights helps you search for flights from Mexico City to Santiago via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Santiago?

Cheapflights helps you find that perfect flight to Santiago from Mexico City by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Mexico City to Santiago with no change fees?

Need flexible booking options for your flight to Santiago from Mexico City? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Mexico City to Santiago become cheaper?

Yes! Start tracking prices for Mexico City to Santiago flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Mexico City to Santiago from £197

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Mexico City to Santiago

Cheapest flights from Mexico City to SantiagoExplore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 December 2025.

Explore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 December 2025.

Find flight deals from Mexico City to Santiago

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Santiago that are best for you.

Best time to book a flight from Mexico City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mexico City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santiago

How far ahead should I book a flight from Mexico City to Santiago?

What is the cheapest month to book a flight from Mexico City to Santiago?

What is the cheapest time of day to fly from MEX to SCL?

Weekly flight availability from Mexico City to Santiago

How often are flights from Mexico City to Santiago delayed?

What is the most punctual flight time for Mexico City to Santiago flights?

What day of the week experiences the fewest flight delays on this route?

Which airline has the best punctuality record on Mexico City to Santiago flights?

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Mexico City to Santiago flight route?

How long is the flight from Mexico City to Santiago?

What are the most reliable airlines from Mexico City to Santiago?

Can I find deals for flights from Mexico City to Santiago that include hotel bookings?

How can I find direct flights from Mexico City to Santiago?

Can I find deals for business class flights from Mexico City to Santiago?

What is the cheapest month to book a flight from Mexico City to Santiago?

Travelling to a place near Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Mexico City to Santiago?

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Santiago?

Can Cheapflights find flights from Mexico City to Santiago with no change fees?

Can Cheapflights notify me if prices for flights from Mexico City to Santiago become cheaper?

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Mexico City to Santiago
Explore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 December 2025.