How long is the flight from San Francisco to Santiago?

Copa Airlines, Delta, and United Airlines can get you from San Francisco to Santiago in just under 18h 55m. Your travel time can differ by up to 4h 09m. There are 5918 mi between San Francisco and Santiago. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 inches per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

What is the cheapest time of day to fly from SFO to SCL?

When flying from San Francisco to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from San Francisco to Santiago that include hotel bookings?

Yes. In addition to deals on San Francisco to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from San Francisco to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago.

Can I find deals for business class flights from San Francisco to Santiago?

Yes. Cheapflights offers flight deals from San Francisco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£308+ Cheap Flights from San Francisco to Santiago

Cheap flight deals from San Francisco to Santiago

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from San Francisco to Santiago
Explore the most affordable flight options available from San Francisco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 September 2026.

Thu 12/1100:33 -

1 stop14h 42m

Sat 21/1112:15 -

1 stop34h 10m

Deal found 22/9£684

Fri 13/1106:00 -

2 stops20h 30m

Sat 21/1123:50 -

1 stop24h 45m

Deal found 21/9£693

Fri 13/1106:00 -

2 stops20h 30m

Tue 1/1209:45 -

2 stops19h 10m

Deal found 21/9£696

Mon 2/1123:00 -

2 stops21h 05m

Sat 7/1107:30 -

2 stops20h 25m

Deal found 20/9£700

Thu 29/1005:00 -

1 stop22h 50m

Tue 10/1122:45 -

1 stop18h 34m

Deal found 21/9£704

Wed 4/1105:00 -

1 stop22h 50m

Wed 9/1222:45 -

1 stop21h 19m

Deal found 23/9£704

Sat 31/1001:33 -

1 stop18h 46m

Sat 7/1112:15 -

1 stop34h 10m

Deal found 21/9£706

Sat 31/1005:00 -

1 stop22h 50m

Sun 15/1122:45 -

1 stop30h 19m

Deal found 22/9£713

Tue 29/911:58 -

1 stop13h 37m

Wed 14/1023:55 -

1 stop24h 23m

Deal found 21/9£715

Sun 4/1007:20 -

2 stops19h 35m

Sun 18/1020:40 -

1 stop24h 45m

Deal found 21/9£719

Tue 24/1100:33 -

1 stop18h 03m

Tue 1/1212:20 -

1 stop34h 05m

Deal found 21/9£721

Mon 21/901:12 -

1 stop15h 20m

Mon 28/903:14 -

1 stop24h 26m

Deal found 21/9£727

Find flight deals from San Francisco to Santiago

Round-trip from	£631
One-way from	£308
Popular in	May
Cheapest in	January
Average price	£600

Copa Airlines
12/3-12/4
2 total stops
45h 19m total
San Francisco to Santiago

Search Deals

16/11-31/12
3 total stops
24h 18m total
San Francisco to Santiago

Search Deals

Highest demand for flights based on searches. 9% potential increase in price (£51 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (£11 potential savings vs. average return price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Mon 16/11

16:57-05:35

2 stops31h 38m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£326

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Thu 31/12

06:25-05:20

2 stops17h 55m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£403

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Sun 18/10

01:12-23:39

1 stop18h 27m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£404

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Sun 18/10

20:21-06:10

1 stop29h 49m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£404

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Sun 4/10

20:21-03:56

1 stop27h 35m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£404

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Sun 11/10

08:00-08:15

1 stop20h 15m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£407

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Tue 20/10

06:00-08:15

1 stop22h 15m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£407

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Tue 13/10

08:00-08:15

1 stop20h 15m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£407

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Fri 13/11

11:51-15:00

2 stops22h 09m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£407

San FranciscoSantiago

SFO San Francisco - SCL Santiago Arturo Merino Benitez

SFOSCL

San Francisco

Thu 28/1

07:30-07:40

1 stop19h 10m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-19:00

Nonstop0h 00m

£407

Flights are sorted by cheapest return flights first.

Deals found on 18/9

Showing 1-10 of 23 resultsSorted by cheapest first

Best time to book a flight from San Francisco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Francisco with our price prediction graph.

SFO-SCL

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago

How far ahead should I book a flight from San Francisco to Santiago?

Booking 40 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Santiago?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Santiago (average of £499). Flying from San Francisco to Santiago in May is currently the most expensive (average of £795). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from San Francisco to Santiago?

Airfare is typical for this route at the moment.

San Francisco to Santiago flights typically cost between £488 and £696 in January.
The cheapest return price found within the last 5 days was £631 on Copa Airlines (6 Jan–15 Jan).

Related info for your journey

How long is the flight from San Francisco to Santiago?
Copa Airlines, Delta, and United Airlines can get you from San Francisco to Santiago in just under 18h 55m. Your travel time can differ by up to 4h 09m. There are 5918 mi between San Francisco and Santiago. This flight may include one or multiple stops.
Can I find deals for flights from San Francisco to Santiago that include hotel bookings?
Yes. In addition to deals on San Francisco to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from San Francisco to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago.
Can I find deals for business class flights from San Francisco to Santiago?
Yes. Cheapflights offers flight deals from San Francisco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Santiago?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Santiago (average of £499). Flying from San Francisco to Santiago in May is currently the most expensive (average of £795). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Why should you use Cheapflights to find cheap flight tickets from San Francisco to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from San Francisco to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from San Francisco to Santiago with no change fees?

Certainly. Search results for flights to Santiago from San Francisco shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from San Francisco to Santiago become cheaper?

Not ready to book yet? You can track prices for flights from San Francisco to Santiago on Cheapflights with our Price Alert feature and get notified when better prices are available.

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Cheap flights from San Francisco to Santiago from £308

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/11. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from San Francisco to Santiago

Cheapest flights from San Francisco to SantiagoExplore the most affordable flight options available from San Francisco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 September 2026.

Explore the most affordable flight options available from San Francisco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 September 2026.

Best flights from San Francisco to SantiagoDiscover carefully curated flight deals from San Francisco to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 23 September 2026.

Discover carefully curated flight deals from San Francisco to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 23 September 2026.

Last-minute flights from San Francisco to SantiagoDiscover last-minute flight deals from San Francisco to Santiago. Data last updated 23 September 2026 and is based on user searches.

Discover last-minute flight deals from San Francisco to Santiago. Data last updated 23 September 2026 and is based on user searches.

One-way flights from San Francisco to SantiagoSearch for one-way flight options from San Francisco to Santiago. Find affordable one-way fares based on user searches. Data last updated 23 September 2026.

Search for one-way flight options from San Francisco to Santiago. Find affordable one-way fares based on user searches. Data last updated 23 September 2026.

Find flight deals from San Francisco to Santiago

Round-trip from

One-way from

Popular in

Cheapest in

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Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago that are best for you.

Best time to book a flight from San Francisco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Francisco with our price prediction graph.

Cheapflights Insights

How far ahead should I book a flight from San Francisco to Santiago?

Booking 40 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Santiago?

How much does it cost for a return flight from San Francisco to Santiago?

Airfare is typical for this route at the moment.

San Francisco to Santiago flights typically cost between £488 and £696 in January.The cheapest return price found within the last 5 days was £631 on Copa Airlines (6 Jan–15 Jan).

Related info for your journey

How long is the flight from San Francisco to Santiago?

Can I find deals for flights from San Francisco to Santiago that include hotel bookings?

How can I find direct flights from San Francisco to Santiago?

Can I find deals for business class flights from San Francisco to Santiago?

What is the cheapest month to book a flight from San Francisco to Santiago?

Travelling to a place near Santiago?

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San Francisco and Santiago flights

Browse other San Francisco and Santiago flight options. Last updated on 23 September 2026.

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How does Cheapflights help users find flights from San Francisco to Santiago?

Why should you use Cheapflights to find cheap flight tickets from San Francisco to Santiago?

Can Cheapflights find flights from San Francisco to Santiago with no change fees?

Can Cheapflights notify me if prices for flights from San Francisco to Santiago become cheaper?

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Cheapest flights from San Francisco to Santiago
Explore the most affordable flight options available from San Francisco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 September 2026.

Best flights from San Francisco to Santiago
Discover carefully curated flight deals from San Francisco to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 23 September 2026.

Last-minute flights from San Francisco to Santiago
Discover last-minute flight deals from San Francisco to Santiago. Data last updated 23 September 2026 and is based on user searches.

One-way flights from San Francisco to Santiago
Search for one-way flight options from San Francisco to Santiago. Find affordable one-way fares based on user searches. Data last updated 23 September 2026.

San Francisco to Santiago flights typically cost between £488 and £696 in January.
The cheapest return price found within the last 5 days was £631 on Copa Airlines (6 Jan–15 Jan).