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Cheap flights from Southampton to Santiago from £875

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 30/10. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SCL
14 Sep — 21 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Santiago

Enter your travel dates to find the best prices.

Best flights from Southampton to Santiago
Discover carefully curated flight deals from Southampton to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 15 August 2026.

Fri 5/217:30 -
2 stops64h 10m
Wed 17/223:10 -
2 stops30h 00m
Deal found 14/8£4,757

Find flight deals from Southampton to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 August 2026.

Round-trip from

£4,258

One-way from

£875

Popular in

December

Cheapest in

January

Average price

£1,053
Delta
  • Delta
  • 6/2-17/2
  • 4 total stops
  • 79h 00m total
  • Southampton to Santiago
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Delta
  • Delta
  • 30/10
  • 2 total stops
  • 41h 10m total
  • Southampton to Santiago
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (£14 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 August 2026.
Use the filters below to find and compare flights from Southampton to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

SouthamptonSantiago

SOU Southampton Eastleigh - SCL Santiago Arturo Merino Benitez

SOUSCL

Southampton Eastleigh

Fri 5/2

17:30-06:40

2 stops64h 10m

Santiago Arturo Merino Benitez

Wed 17/2

23:10-08:10

2 stops30h 00m

£4,757
Cheapest one-way
Fastest single journey

SouthamptonSantiago

SOU Southampton Eastleigh - SCL Santiago Arturo Merino Benitez

SOUSCL

Southampton Eastleigh

Fri 30/10

17:30-07:40

2 stops41h 10m

£875

SouthamptonSantiago

SOU Southampton Eastleigh - SCL Santiago Arturo Merino Benitez

SOUSCL

Southampton Eastleigh

Thu 5/11

17:30-07:40

2 stops41h 10m

£875

SouthamptonSantiago

SOU Southampton Eastleigh - SCL Santiago Arturo Merino Benitez

SOUSCL

Southampton Eastleigh

Sat 31/10

17:30-07:40

2 stops41h 10m

£875

Flights are sorted by cheapest return flights first.

Deals found on 11/8

Sorted by cheapest first

Best time to book a flight from Southampton to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 15 August 2026.
See what other customers who have flown with KLM from Southampton to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,559 reviews
Check prices

Comfort

7.7

Overall

7.8

Crew

8.4

Food

7.3

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
4.0
Okay

Abhisek,Aug 2026

JFK - AMS

They didn’t offer any options for breakfast and had only one option which was cold meat and cheese. I would expect at least one more option in premium economy
KLM
7.8
Good
1,559 reviews
KLM
7.8
Good
1,559 reviews
Check prices

Comfort

7.7

Overall

7.8

Crew

8.4

Food

7.3

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
4.0
Okay

Abhisek,Aug 2026

JFK - AMS

They didn’t offer any options for breakfast and had only one option which was cold meat and cheese. I would expect at least one more option in premium economy

Related info for your journey

Find useful and relevant information for your journey from Southampton to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to Santiago?

    For as low as £4,757, Delta can have you in Santiago from Southampton in 64h 10m. The distance from Southampton to Santiago is about 7183 mi.

  • Can I find deals for flights from Southampton to Santiago that include hotel bookings?

    Yes. In addition to deals on Southampton to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Santiago.

  • Can I find deals for business class flights from Southampton to Santiago?

    Yes. Cheapflights offers flight deals from Southampton to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Southampton to Santiago

Discover the top airline that operate flights from Southampton to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 August 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest£1,189Average£1,321FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to Santiago?

Deals for Southampton to Santiago flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Santiago?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Santiago for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Santiago with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Southampton to Santiago, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Southampton to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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