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Cheap flights from Southampton to Santiago from £1,009

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SCL
17 Apr — 24 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Santiago
Explore the most affordable flight options available from Southampton to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 March 2026.

Tue 10/1117:30
SOU
-
SCL
2 stops65h 10m
Delta
Tue 17/1123:10
SCL
-
SOU
2 stops38h 50m
Delta
Deal found 17/3£1,009
Tue 28/409:05
SOU
-
SCL
2 stops27h 45m
KLM
Tue 5/510:10
SCL
-
SOU
2 stops41h 25m
KLM
Deal found 14/3£1,066
Fri 3/417:20
SOU
-
SCL
2 stops42h 55m
Delta
Fri 17/420:40
SCL
-
SOU
2 stops54h 55m
Delta
Deal found 17/3£1,158
Tue 31/309:05
SOU
-
SCL
2 stops27h 45m
KLM
Wed 15/410:15
SCL
-
SOU
2 stops25h 35m
KLM
Deal found 17/3£1,165
Wed 1/409:05
SOU
-
SCL
2 stops27h 45m
KLM
Wed 15/410:15
SCL
-
SOU
2 stops25h 35m
KLM
Deal found 17/3£1,177
Mon 30/317:20
SOU
-
SCL
2 stops42h 55m
Delta
Mon 13/420:40
SCL
-
SOU
2 stops39h 10m
Delta
Deal found 17/3£1,197
Fri 3/417:20
SOU
-
SCL
2 stops42h 55m
Delta
Sat 18/420:40
SCL
-
SOU
2 stops54h 55m
Delta
Deal found 17/3£1,208
Tue 28/409:05
SOU
-
SCL
3 stops44h 35m
Multiple Airlines
Tue 5/505:00
SCL
-
SOU
3 stops29h 00m
Multiple Airlines
Deal found 14/3£1,225
Mon 30/317:20
SOU
-
SCL
2 stops42h 55m
Delta
Sat 18/420:40
SCL
-
SOU
2 stops54h 55m
Delta
Deal found 17/3£1,247
Tue 31/309:05
SOU
-
SCL
2 stops27h 45m
KLM
Tue 14/410:15
SCL
-
SOU
2 stops41h 20m
KLM
Deal found 17/3£1,254
Wed 1/409:05
SOU
-
SCL
2 stops27h 45m
KLM
Tue 14/410:15
SCL
-
SOU
2 stops25h 35m
KLM
Deal found 17/3£1,267

Find flight deals from Southampton to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 March 2026.

Round-trip from

£1,066

Popular in

December

Cheapest in

June

Average price

£926
KLM
  • KLM
  • 28/4-5/5
  • 4 total stops
  • 69h 10m total
  • Southampton to Santiago
Search Deals
Highest demand for flights based on searches. 1% potential increase in price (£14 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 March 2026.
Use the filters below to find and compare flights from Southampton to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Tue 28/4

09:05-07:50

2 stops27h 45m

Santiago Arturo Merino Benitez

Tue 5/5

10:10-08:35

2 stops41h 25m

£1,066

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Mon 30/3

17:20-08:15

2 stops42h 55m

Santiago Arturo Merino Benitez

Mon 13/4

20:40-16:50

2 stops39h 10m

£1,197

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Fri 3/4

17:20-08:15

2 stops42h 55m

Santiago Arturo Merino Benitez

Sat 18/4

20:40-08:35

2 stops54h 55m

£1,208

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Tue 28/4

09:05-00:40

3 stops44h 35m

Santiago Arturo Merino Benitez

Tue 5/5

05:00-15:00

3 stops29h 00m

£1,225

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Tue 31/3

09:05-08:15

2 stops27h 10m

Santiago Arturo Merino Benitez

Sat 18/4

20:40-08:35

2 stops54h 55m

£1,247
Fastest return journey

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Thu 2/4

09:05-08:50

2 stops27h 45m

Santiago Arturo Merino Benitez

Tue 14/4

10:15-08:35

2 stops41h 20m

£1,267

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Sun 29/3

17:20-08:15

2 stops42h 55m

Santiago Arturo Merino Benitez

Fri 17/4

20:40-08:35

2 stops54h 55m

£1,322

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Wed 1/4

09:05-08:15

2 stops27h 10m

Santiago Arturo Merino Benitez

Sat 18/4

20:40-08:35

2 stops54h 55m

£1,383

Flights are sorted by cheapest return flights first.

Deals found on 14/3

Sorted by cheapest first

Best time to book a flight from Southampton to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Santiago

What is the cheapest month to book a flight from Southampton to Santiago?

Currently, November is the cheapest month in which you can book a flight from Southampton to Santiago (average of £664). Flying from Southampton to Santiago in July is currently the most expensive (average of £878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to Santiago?

    For as low as £1,066, KLM can have you in Santiago from Southampton in 27h 45m. The distance from Southampton to Santiago is about 7183 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Santiago that include hotel bookings?

    Yes. In addition to deals on Southampton to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Santiago.

  • Can I find deals for business class flights from Southampton to Santiago?

    Yes. Cheapflights offers flight deals from Southampton to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Southampton to Santiago (average of £664). Flying from Southampton to Santiago in July is currently the most expensive (average of £878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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How does Cheapflights help users find flights from Southampton to Santiago?

Deals for Southampton to Santiago flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Santiago?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Santiago for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Santiago with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Southampton to Santiago, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Southampton to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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