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Cheap flights from Southampton to Santiago from £2,162

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SCL
17 Jan — 24 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Santiago

Enter your travel dates to find the best prices.

Best flights from Southampton to Santiago
Discover carefully curated flight deals from Southampton to Santiago that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 18 December 2025.

Fri 2/108:40SOU - SCL
2 stops50h 00mDelta
Thu 8/123:10SCL - SOU
2 stops30h 35mDelta
Deal found 16/12£2,162
Fri 2/108:40SOU - SCL
2 stops48h 30mDelta
Sat 10/121:30SCL - SOU
2 stops32h 20mDelta
Deal found 16/12£2,363
Fri 2/108:40SOU - SCL
2 stops50h 00mDelta
Fri 9/121:30SCL - SOU
2 stops56h 20mDelta
Deal found 16/12£2,463
Sun 4/118:05SOU - SCL
2 stops40h 35mDelta
Sat 10/123:10SCL - SOU
2 stops54h 40mDelta
Deal found 16/12£2,562
Sun 4/118:05SOU - SCL
2 stops64h 35mDelta
Fri 9/123:10SCL - SOU
2 stops39h 05mDelta
Deal found 16/12£2,663
Sat 3/109:25SOU - SCL
2 stops47h 45mDelta
Thu 8/123:10SCL - SOU
2 stops30h 35mDelta
Deal found 16/12£2,680
Sat 3/117:30SOU - SCL
2 stops63h 40mDelta
Sat 10/123:10SCL - SOU
2 stops54h 40mDelta
Deal found 16/12£2,840

Find flight deals from Southampton to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 December 2025.

Round-trip from

£2,162

Popular in

December

Cheapest in

June

Average price

£1,137
Delta
  • Delta
  • 2/1-8/1
  • 4 total stops
  • 80h 35m total
  • Southampton to Santiago
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£32 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 December 2025.
Use the filters below to find and compare flights from Southampton to Santiago that are best for you.

Fly from

Southampton

Fly to

Santiago

Route

Depart

Return

Price

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Fri 2/1

08:40-07:40

2 stops50h 00m

Santiago Arturo Merino Benitez

Thu 8/1

23:10-08:45

2 stops30h 35m

£2,162

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Fri 2/1

08:40-06:10

2 stops48h 30m

Santiago Arturo Merino Benitez

Sat 10/1

21:30-08:50

2 stops32h 20m

£2,363

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Fri 2/1

08:40-07:40

2 stops50h 00m

Santiago Arturo Merino Benitez

Fri 9/1

21:30-08:50

2 stops56h 20m

£2,463

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Sun 4/1

18:05-07:40

2 stops40h 35m

Santiago Arturo Merino Benitez

Sat 10/1

23:10-08:50

2 stops54h 40m

£2,562

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Sun 4/1

18:05-07:40

2 stops64h 35m

Santiago Arturo Merino Benitez

Fri 9/1

23:10-17:15

2 stops39h 05m

£2,663

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Sat 3/1

09:25-06:10

2 stops47h 45m

Santiago Arturo Merino Benitez

Thu 8/1

23:10-08:45

2 stops30h 35m

£2,680

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Sat 3/1

17:30-06:10

2 stops63h 40m

Santiago Arturo Merino Benitez

Sat 10/1

23:10-08:50

2 stops54h 40m

£2,840

Flights are sorted by cheapest return flights first.

Deals found on 16/12

Best time to book a flight from Southampton to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Santiago

What is the cheapest month to book a flight from Southampton to Santiago?

Currently, November is the cheapest month in which you can book a flight from Southampton to Santiago (average of £595). Flying from Southampton to Santiago in December is currently the most expensive (average of £799). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to Santiago?

    For as low as £2,162, Delta can have you in Santiago from Southampton in 50h. The distance from Southampton to Santiago is about 7183 mi.

  • Can I find deals for flights from Southampton to Santiago that include hotel bookings?

    Yes. In addition to deals on Southampton to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Santiago.

  • Can I find deals for business class flights from Southampton to Santiago?

    Yes. Cheapflights offers flight deals from Southampton to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Southampton to Santiago (average of £595). Flying from Southampton to Santiago in December is currently the most expensive (average of £799). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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How does Cheapflights help users find flights from Southampton to Santiago?

Deals for Southampton to Santiago flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Santiago?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Santiago for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Santiago with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Southampton to Santiago, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Southampton to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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