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Cheap flights from London Heathrow Airport to São Tomé from £638

LHR — TMS
21 Sep — 28 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to São Tomé

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to São Tomé

Fri 16/1019:50 -
2 stops45h 55m
Sun 25/1017:45 -
2 stops28h 55m
Deal found 21/8£638
Fri 16/1019:50 -
1 stop22h 35m
Sun 25/1020:00 -
2 stops26h 40m
Deal found 21/8£984
Sat 14/1118:30 -
2 stops23h 45m
Fri 4/1220:00 -
2 stops26h 40m
Deal found 17/8£1,002
Fri 23/1006:00 -
2 stops12h 45m
Fri 27/1118:20 -
2 stops24h 35m
Deal found 21/8£1,007
Fri 23/1019:50 -
1 stop22h 35m
Fri 27/1120:00 -
1 stop25h 35m
Deal found 21/8£1,015

Find flight deals from Heathrow to São Tomé

Round-trip from

£638

Popular in

February

Cheapest in

March

Average price

£1,010
16/10-25/10
  • 16/10-25/10
  • 4 total stops
  • 74h 50m total
  • London to São Tomé
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£88 potential increase over avg. return price).
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Cheapest flight prices on average. 4% potential price decrease (£32 potential savings vs. average return price).
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Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from London Heathrow Airport to São Tomé that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Fri 16/10

19:50-16:45

2 stops45h 55m

Sao Tome Is

Sun 25/10

17:45-12:40

2 stops18h 55m

£656
Fastest return journey

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 30/1

06:00-17:30

1 stop11h 30m

Sao Tome Is

Sat 13/2

22:25-11:25

1 stop13h 00m

£978

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Fri 16/10

19:50-17:25

1 stop22h 35m

Sao Tome Is

Sun 25/10

20:00-22:40

2 stops26h 40m

£984

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 14/11

18:30-18:15

2 stops23h 45m

Sao Tome Is

Fri 4/12

20:00-22:40

2 stops26h 40m

£1,002

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Fri 23/10

06:00-17:45

2 stops12h 45m

Sao Tome Is

Fri 27/11

18:20-18:55

2 stops24h 35m

£1,007
Cheapest one-way

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Tue 8/9

09:55-17:45

3 stops32h 50m

£693

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Tue 8/9

19:50-17:45

1 stop22h 55m

£740
Fastest single journey

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 29/8

06:00-17:25

1 stop12h 25m

£795

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Sat 29/8

21:10-17:30

3 stops45h 20m

£917

LondonSão Tomé

LHR London Heathrow - TMS Sao Tome Is

LHRTMS

London Heathrow

Mon 28/9

15:30-11:45

3 stops45h 15m

£966

Flights are sorted by cheapest return flights first.

Deals found on 21/8

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Heathrow to São Tomé

Have a flexible travel schedule? Discover the best time to fly to São Tomé from Heathrow with our price prediction graph.
Estimated return price

Reviews of airlines servicing São Tomé

Check out reviews from past customers who have flown with TAP AIR PORTUGAL from London Heathrow Airport to São Tomé to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
TAP AIR PORTUGAL
7.2
Good
2,372 reviews
Check prices

Food

6.3

Boarding

7.0

Entertainment

6.4

Comfort

7.2

Overall

7.2

Crew

7.8

Reviews

1 / 20
4.0
Okay

Bhairav,Jun 2026

LHR - LIS

Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.
TAP AIR PORTUGAL
7.2
Good
2,372 reviews
TAP AIR PORTUGAL
7.2
Good
2,372 reviews
Check prices

Food

6.3

Boarding

7.0

Entertainment

6.4

Comfort

7.2

Overall

7.2

Crew

7.8

Reviews

1 / 20
4.0
Okay

Bhairav,Jun 2026

LHR - LIS

Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.

Related info for your journey

  • What airport do you fly into for flights to São Tomé from London Heathrow?

    Sao Tome Is (TMS) is the airport you will fly into if you book a flight from London Heathrow to São Tomé. You should not have trouble finding flights to Sao Tome Is from London Heathrow; the airport handles an average of 0 inbound flights from London Heathrow per day. You should also have plenty of airline options to choose from since 1 airline has flights to the São Tomé airport from London Heathrow. It is only a 3.1 mi journey from Sao Tome Is (TMS) to São Tomé’s city center.

  • How long is the flight from London Heathrow Airport to São Tomé?

    Departing from London Heathrow Airport to São Tomé will take you 11h 30m. The distance between London Heathrow Airport and São Tomé is about 3552 mi.

  • What is the cheapest airline to fly from London Heathrow Airport to São Tomé round-trip?

    Cheapflights users have booked flights from London Heathrow Airport to São Tomé round-trip from £695. You may be able to fly from London Heathrow Airport to São Tomé for 31% less than the average price by searching for this airline.

  • Can I find deals for flights from Heathrow to São Tomé that include hotel bookings?

    Yes. In addition to deals on Heathrow to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to São Tomé?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to São Tomé.

  • Can I find deals for business class flights from Heathrow to São Tomé?

    Yes. Cheapflights offers flight deals from Heathrow to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Heathrow to São Tomé

Gatwick to São Tomé flights

Top airline flying from Heathrow to São Tomé

AirlineCheapestAverageFlexibilityOn-time
TAP AIR PORTUGALCheapest£695Average£839FlexibilityNo cancel feeOn-timeN/A
Search TAP AIR PORTUGAL flights

Fly with Cheapflights

How does Cheapflights help users find flights from Heathrow to São Tomé?

When you search for this flight from Heathrow to São Tomé, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to São Tomé?

Cheapflights helps you find that perfect flight to São Tomé from Heathrow by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Heathrow to São Tomé with no change fees?

Certainly. Search results for flights to São Tomé from Heathrow shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Heathrow to São Tomé become cheaper?

Yes, Cheapflights offers price alerts on Heathrow to São Tomé flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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