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Cheap flights from London Heathrow Airport to São Tomé from £415

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — TMS
9 Apr — 16 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to São Tomé

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to São Tomé
Explore the most affordable flight options available from Heathrow to São Tomé. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 March 2026.

Thu 16/416:35
LHR
-
TMS
2 stops20h 35m
Multiple Airlines
Wed 22/413:10
TMS
-
LHR
2 stops31h 50m
Multiple Airlines
Deal found 7/3£543
Thu 16/416:35
LHR
-
TMS
2 stops20h 35m
Multiple Airlines
Mon 27/413:10
TMS
-
LHR
2 stops27h 35m
Multiple Airlines
Deal found 8/3£544
Tue 8/1212:00
LHR
-
TMS
2 stops24h 10m
Multiple Airlines
Wed 30/1213:10
TMS
-
LHR
2 stops26h 40m
Multiple Airlines
Deal found 6/3£700
Sat 21/1106:00
LHR
-
TMS
1 stop11h 30m
Multiple Airlines
Wed 2/1213:10
TMS
-
LHR
2 stops23h 30m
Multiple Airlines
Deal found 9/3£717
Mon 7/1218:30
LHR
-
TMS
2 stops41h 40m
Multiple Airlines
Wed 30/1213:10
TMS
-
LHR
2 stops29h 45m
Multiple Airlines
Deal found 6/3£727
Sat 21/1106:00
LHR
-
TMS
1 stop11h 30m
TAP AIR PORTUGAL
Sat 28/1122:25
TMS
-
LHR
1 stop13h 00m
TAP AIR PORTUGAL
Deal found 9/3£738
Fri 20/1118:30
LHR
-
TMS
1 stop11h 50m
Multiple Airlines
Wed 2/1213:10
TMS
-
LHR
2 stops23h 30m
Multiple Airlines
Deal found 9/3£739
Sat 11/406:00
LHR
-
TMS
1 stop12h 25m
Multiple Airlines
Mon 20/413:10
TMS
-
LHR
2 stops27h 35m
Multiple Airlines
Deal found 8/3£740
Fri 20/1118:30
LHR
-
TMS
1 stop11h 50m
Multiple Airlines
Sat 28/1107:50
TMS
-
LHR
1 stop11h 05m
Multiple Airlines
Deal found 9/3£756
Fri 8/519:50
LHR
-
TMS
1 stop22h 35m
TAP AIR PORTUGAL
Fri 15/519:40
TMS
-
LHR
2 stops26h 15m
TAP AIR PORTUGAL
Deal found 5/3£761

Find flight deals from Heathrow to São Tomé

Discover tips and strategies to find the most affordable flight options for your journey from Heathrow (LHR) to São Tomé (TMS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 March 2026.

Round-trip from

£543

One-way from

£415

Popular in

January

Cheapest in

November

Average price

£826
16/4-22/4
  • 16/4-22/4
  • 4 total stops
  • 52h 25m total
  • London to São Tomé
Search Deals
1/9
  • 1/9
  • 2 total stops
  • 14h 35m total
  • London to São Tomé
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£81 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£23 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to São Tomé that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 March 2026.
Use the filters below to find and compare flights from London Heathrow Airport to São Tomé that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Fri 8/5

19:50-17:25

1 stop22h 35m

Sao Tome Is

Fri 15/5

19:40-22:55

2 stops26h 15m

£761

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Mon 6/4

08:00-12:10

2 stops53h 10m

Sao Tome Is

Mon 13/4

13:10-22:55

2 stops32h 45m

£788

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Sat 2/5

13:45-17:45

2 stops29h 00m

Sao Tome Is

Sun 10/5

19:40-12:45

2 stops16h 05m

£856
Fastest return journey

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Sat 11/4

06:00-17:25

1 stop12h 25m

Sao Tome Is

Sun 19/4

19:40-22:55

1 stop26h 15m

£888

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Tue 23/6

19:50-17:45

2 stops22h 55m

Sao Tome Is

Wed 1/7

19:40-12:45

2 stops16h 05m

£960
Cheapest one-way
Fastest single journey

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Tue 1/9

15:50-05:25

2 stops14h 35m

£415

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Fri 8/5

19:50-17:25

1 stop22h 35m

£440

LondonSão Tomé

LHR - TMS

LHRTMS

London Heathrow

Fri 8/5

22:15-17:45

3 stops44h 30m

£563

Flights are sorted by cheapest return flights first.

Deals found on 7/3

Sorted by cheapest first

Best time to book a flight from Heathrow to São Tomé

Have a flexible travel schedule? Discover the best time to fly to São Tomé from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to São Tomé

How much does it cost for a return flight from London Heathrow Airport to São Tomé?

Reviews of airlines servicing São Tomé

Get insights into the airlines that provide service to São Tomé. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to São Tomé. Reviews last updated 10 March 2026.
Check out reviews from past customers who have flown with TAP AIR PORTUGAL from London Heathrow Airport to São Tomé to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
TAP AIR PORTUGAL
7.1
Good
2,163 reviews
Check prices

Food

6.2

Entertainment

6.3

Boarding

7.0

Overall

7.1

Comfort

7.1

Crew

7.8

Reviews

1 / 20
2.0
Mediocre

Claudia,Jul 2025

EWR - LIS

Never made the trip. Had to cancel due to multiple delays
TAP AIR PORTUGAL
7.1
Good
2,163 reviews
TAP AIR PORTUGAL
7.1
Good
2,163 reviews
Check prices

Food

6.2

Entertainment

6.3

Boarding

7.0

Overall

7.1

Comfort

7.1

Crew

7.8

Reviews

1 / 20
2.0
Mediocre

Claudia,Jul 2025

EWR - LIS

Never made the trip. Had to cancel due to multiple delays

Related info for your journey

Find useful and relevant information for your journey from Heathrow to São Tomé. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to São Tomé from London Heathrow?

    Sao Tome Is (TMS) is the airport you will fly into if you book a flight from London Heathrow to São Tomé. You should not have trouble finding flights to Sao Tome Is from London Heathrow; the airport handles an average of 0 inbound flights from London Heathrow per day. You should also have plenty of airline options to choose from since 1 airline has flights to the São Tomé airport from London Heathrow. It is only a 3.1 mi journey from Sao Tome Is (TMS) to São Tomé’s city center.

  • How long is the flight from London Heathrow Airport to São Tomé?

    Departing from London Heathrow Airport to São Tomé will take you 22h 35m. The distance between London Heathrow Airport and São Tomé is about 3552 mi.

  • What is the cheapest airline to fly from London Heathrow Airport to São Tomé round-trip?

    Cheapflights users have booked flights from London Heathrow Airport to São Tomé round-trip from £764. You may be able to fly from London Heathrow Airport to São Tomé for 21% less than the average price by searching for this airline.

  • Can I find deals for flights from Heathrow to São Tomé that include hotel bookings?

    Yes. In addition to deals on Heathrow to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to São Tomé?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to São Tomé.

  • Can I find deals for business class flights from Heathrow to São Tomé?

    Yes. Cheapflights offers flight deals from Heathrow to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Heathrow to São Tomé

See prices for flight routes from nearby airports that may be better suited for you.
Gatwick to São Tomé flights

Top airline flying from Heathrow to São Tomé

Discover the top airline that operate flights from Heathrow to São Tomé. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 March 2026.
AirlineCheapestAverageFlexibilityOn-time
TAP AIR PORTUGALCheapest£764Average£906FlexibilityNo cancel feeOn-timeN/A
Search TAP AIR PORTUGAL flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Heathrow to São Tomé?

When you search for this flight from Heathrow to São Tomé, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to São Tomé?

Cheapflights helps you find that perfect flight to São Tomé from Heathrow by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Heathrow to São Tomé with no change fees?

Certainly. Search results for flights to São Tomé from Heathrow shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Heathrow to São Tomé become cheaper?

Yes, Cheapflights offers price alerts on Heathrow to São Tomé flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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