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Cheap flights from Panama to Manchester from £449

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
1 Jun — 8 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama to Manchester
Explore the most affordable flight options available from Panama to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 May 2026.

Fri 18/910:00
PTY
-
MAN
3 stops38h 30m
United Airlines
Mon 21/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 29/4£746
Mon 18/520:25
PTY
-
MAN
1 stop16h 55m
Multiple Airlines
Wed 27/506:35
MAN
-
PTY
1 stop18h 05m
Multiple Airlines
Deal found 29/4£782
Mon 18/520:25
PTY
-
MAN
1 stop16h 55m
Multiple Airlines
Thu 28/507:05
MAN
-
PTY
1 stop17h 35m
Multiple Airlines
Deal found 29/4£797
Mon 11/520:25
PTY
-
MAN
1 stop16h 55m
Multiple Airlines
Sun 17/521:35
MAN
-
PTY
2 stops27h 05m
Multiple Airlines
Deal found 30/4£798
Fri 22/520:25
PTY
-
MAN
1 stop16h 30m
Multiple Airlines
Wed 27/506:35
MAN
-
PTY
1 stop18h 05m
Multiple Airlines
Deal found 29/4£802
Sat 23/520:25
PTY
-
MAN
1 stop15h 50m
Multiple Airlines
Wed 27/506:35
MAN
-
PTY
1 stop18h 05m
Multiple Airlines
Deal found 29/4£813
Fri 22/520:25
PTY
-
MAN
1 stop16h 30m
Multiple Airlines
Thu 28/507:05
MAN
-
PTY
1 stop17h 35m
Multiple Airlines
Deal found 29/4£817
Sun 31/522:55
PTY
-
MAN
2 stops49h 35m
United Airlines
Sun 14/609:00
MAN
-
PTY
2 stops25h 04m
United Airlines
Deal found 27/4£819
Fri 14/822:55
PTY
-
MAN
2 stops25h 35m
United Airlines
Sun 13/909:00
MAN
-
PTY
2 stops40h 31m
United Airlines
Deal found 28/4£820
Sat 23/522:55
PTY
-
MAN
2 stops52h 55m
United Airlines
Wed 27/506:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 29/4£820
Sat 23/520:25
PTY
-
MAN
1 stop15h 50m
Multiple Airlines
Thu 28/507:05
MAN
-
PTY
1 stop17h 35m
Multiple Airlines
Deal found 29/4£828
Sat 19/909:50
DAV
-
MAN
2 stops44h 15m
Turkish Airlines
Wed 23/917:35
MAN
-
DAV
3 stops45h 35m
Turkish Airlines
Deal found 30/4£1,153

Find flight deals from Panama to Manchester

Keep the following information in mind while searching for Panama to Manchester flight deals. Data was last updated 2 May 2026.

Round-trip from

£746

One-way from

£449

Popular in

September

Cheapest in

July
United Airlines
  • United Airlines
  • 18/9-21/9
  • 5 total stops
  • 57h 56m total
  • Panama to Manchester
Search Deals
23/6
  • 23/6
  • 3 total stops
  • 49h 10m total
  • Panama to Manchester
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£79 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease (£57 potential savings vs. average return price).
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 May 2026.
Use the filters below to find and compare flights from Panama to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 18/9

15:30-06:30

2 stops33h 00m

Manchester

Mon 21/9

06:05-19:31

2 stops19h 26m

£746

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

22:55-06:30

2 stops49h 35m

Manchester

Sun 14/6

09:00-04:04

2 stops25h 04m

£819

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 14/8

22:55-06:30

2 stops25h 35m

Manchester

Wed 16/9

09:00-19:31

2 stops40h 31m

£820

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 23/5

22:55-09:50

2 stops52h 55m

Manchester

Wed 27/5

06:05-19:31

2 stops19h 26m

£820

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 20/8

22:55-06:30

2 stops49h 35m

Manchester

Tue 15/9

06:05-19:31

2 stops19h 26m

£834

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 5/9

22:55-10:25

2 stops29h 30m

Manchester

Wed 9/9

06:05-19:31

2 stops19h 26m

£848

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 15/8

22:55-17:20

2 stops36h 25m

Manchester

Thu 17/9

06:05-19:31

2 stops19h 26m

£861

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 22/6

09:45-10:25

2 stops18h 40m

Manchester

Wed 2/9

06:05-04:04

2 stops27h 59m

£867
Fastest return journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 21/5

09:45-10:25

2 stops18h 40m

Manchester

Wed 27/5

06:05-19:31

2 stops19h 26m

£867

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 21/5

09:45-10:25

2 stops18h 40m

Manchester

Thu 28/5

06:05-19:31

2 stops19h 26m

£867

Flights are sorted by cheapest return flights first.

Deals found on 1/5

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Panama to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Manchester
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Panama?

    Manchester (MAN) is the airport you will fly into if you book a flight from Panama to Manchester. It is only a 8.9 mi journey from Manchester (MAN) to Manchester’s city center.

  • How long is the flight from Panama to Manchester?

    United Airlines and Turkish Airlines can get you from Panama to Manchester in just under 33h. Your travel time can differ by up to 11h 15m. The distance between Panama and Manchester is about 5182 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Manchester.

  • Can I find deals for business class flights from Panama to Manchester?

    Yes. Cheapflights offers flight deals from Panama to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

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Derby
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Telford
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Wilmslow
Macclesfield

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