What is the most punctual flight time for Panama City to Guayaquil flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

Which airline has the best punctuality record on Panama City to Guayaquil flights?

Over the past year, Copa Airlines have had the lowest number of delays on this route, with just 7% of flights being delayed.

How often are flights from Panama City to Guayaquil delayed?

About 7% of weekly flights between Panama City and Guayaquil have experienced delays in the past year, with the average delay time being 100 minutes.

What day of the week experiences the fewest flight delays on this route?

Wednesday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.

How popular is this Panama City to Guayaquil flight route?

This flight path from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Panama City to Guayaquil?

Departing from Panama City to Guayaquil will take you 2h 13m. There are 776 mi between Panama City and Guayaquil. Most flights are nonstop.

Weekly flight availability from Panama City to Guayaquil

The most flights from PTY to GYE are scheduled on a Monday (15 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (11 on average).

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 280.0 inches per month. March is typically the wettest month, when rainfall can reach 280.0 mm. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 mm.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 25.0 C).

What are the most reliable airlines from Panama City to Guayaquil?

Consider KLM (89%), United Airlines (87%) or Copa Airlines (87%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Guayaquil.

Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?

Yes. In addition to deals on Panama City to Guayaquil flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Panama City to Guayaquil?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guayaquil.

Can I find deals for business class flights from Panama City to Guayaquil?

Yes. Cheapflights offers flight deals from Panama City to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£172+ Cheap Flights from Panama City to Guayaquil

Cheap flight deals from Panama City to Guayaquil

Enter your travel dates to find the best prices.

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Cheapest flights from Panama City to Guayaquil
Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 September 2026.

Mon 5/1021:48 -

Nonstop2h 13m

Wed 14/1012:18 -

Nonstop2h 16m

Deal found 17/9£311

Sat 31/1009:02 -

Nonstop2h 13m

Fri 6/1104:22 -

Nonstop2h 12m

Deal found 16/9£324

Mon 5/1009:08 -

Nonstop2h 13m

Mon 12/1015:45 -

1 stop8h 50m

Deal found 17/9£331

Mon 5/1009:08 -

Nonstop2h 13m

Wed 14/1018:50 -

1 stop14h 25m

Deal found 17/9£331

Wed 30/909:08 -

Nonstop2h 13m

Wed 7/1006:01 -

Nonstop2h 11m

Deal found 16/9£337

Mon 5/1015:10 -

1 stop17h 45m

Tue 13/1010:05 -

1 stop23h 10m

Deal found 17/9£349

Sat 19/909:08 -

Nonstop2h 13m

Mon 21/912:22 -

Nonstop2h 12m

Deal found 16/9£368

Fri 23/1011:21 -

Nonstop2h 12m

Fri 30/1018:40 -

Nonstop2h 10m

Deal found 20/9£370

Mon 21/909:08 -

Nonstop2h 13m

Wed 23/918:28 -

Nonstop2h 12m

Deal found 18/9£375

Mon 5/1017:55 -

2 stops24h 00m

Mon 12/1018:50 -

1 stop5h 45m

Deal found 17/9£381

Sat 12/1218:40 -

Nonstop2h 17m

Fri 8/104:21 -

Nonstop2h 13m

Deal found 16/9£393

Find flight deals from Panama City to Guayaquil

Round-trip from	£311
One-way from	£172
Popular in	June
Cheapest in	February
Average price	£287

Copa Airlines
5/10-12/10
Nonstop
4h 28m total
Panama City to Guayaquil

Search Deals

Copa Airlines
5/10-31/12
Nonstop
2h 13m total
Panama City to Guayaquil

Search Deals

Highest demand for flights based on searches. 5% potential increase in price (£11 potential increase over avg. return price).

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Cheapest flight prices on average. 0% potential price decrease (£2 potential savings vs. average return price).

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Average for round-trip flights in September 2026

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Guayaquil that are best for you.

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Price

Cheapest return flight

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Sun 27/9

08:20-10:34

Nonstop2h 14m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-00:00

Nonstop0h 00m

£174

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Sat 26/12

11:27-13:42

Nonstop2h 15m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-00:00

Nonstop0h 00m

£174

Fastest return journey

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Mon 19/10

09:08-11:21

Nonstop2h 13m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-00:00

Nonstop0h 00m

£174

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Mon 28/9

21:48-00:01

Nonstop2h 13m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-00:00

Nonstop0h 00m

£174

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Sun 22/11

21:39-23:55

Nonstop2h 16m

Guayaquil Jose Joaquin de Olmedo

Wed 31/12

00:00-00:00

Nonstop0h 00m

£174

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Sat 31/10

09:02-11:15

Nonstop2h 13m

Guayaquil Jose Joaquin de Olmedo

Fri 6/11

04:22-06:34

Nonstop2h 12m

£324

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Tue 27/10

18:40-20:53

Nonstop2h 13m

Guayaquil Jose Joaquin de Olmedo

Wed 4/11

05:54-08:08

Nonstop2h 14m

£324

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Mon 2/11

18:40-20:56

Nonstop2h 16m

Guayaquil Jose Joaquin de Olmedo

Mon 9/11

14:47-17:01

Nonstop2h 14m

£324

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Sat 31/10

21:48-00:01

Nonstop2h 13m

Guayaquil Jose Joaquin de Olmedo

Wed 4/11

14:47-17:01

Nonstop2h 14m

£324

Panama CityGuayaquil

PTY Panama City Tocumen Intl - GYE Guayaquil Jose Joaquin de Olmedo

PTYGYE

Panama City Tocumen Intl

Sun 18/10

11:21-13:33

Nonstop2h 12m

Guayaquil Jose Joaquin de Olmedo

Tue 27/10

12:23-14:39

Nonstop2h 16m

£337

Flights are sorted by cheapest return flights first.

Deals found on 16/9

Showing 1-10 of 14 resultsSorted by cheapest first

Best time to book a flight from Panama City to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Panama City with our price prediction graph.

PTY-GYE

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Guayaquil

Prices

Airlines

Delays

How far ahead should I book a flight from Panama City to Guayaquil?

Booking 78 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Guayaquil?

Currently, February is the cheapest month in which you can book a flight from Panama City to Guayaquil (average of £246). Flying from Panama City to Guayaquil in June is currently the most expensive (average of £296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to GYE?

When flying from Panama City to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Panama City to Guayaquil?

Airfare is typical for this route at the moment.

Panama City to Guayaquil flights typically cost between £192 and £328 in October.
The cheapest return price found within the last 5 days was £311 on Copa Airlines (5 Oct–12 Oct).

Related info for your journey

How popular is this Panama City to Guayaquil flight route?
This flight path from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Panama City to Guayaquil?
Departing from Panama City to Guayaquil will take you 2h 13m. There are 776 mi between Panama City and Guayaquil. Most flights are nonstop.
What are the most reliable airlines from Panama City to Guayaquil?
Consider KLM (89%), United Airlines (87%) or Copa Airlines (87%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Guayaquil.
Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?
Yes. In addition to deals on Panama City to Guayaquil flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Panama City to Guayaquil?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guayaquil.
Can I find deals for business class flights from Panama City to Guayaquil?
Yes. Cheapflights offers flight deals from Panama City to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to Guayaquil?
Currently, February is the cheapest month in which you can book a flight from Panama City to Guayaquil (average of £246). Flying from Panama City to Guayaquil in June is currently the most expensive (average of £296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Cheapflights helps you search for flights from Panama City to Guayaquil via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Guayaquil?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama City to Guayaquil.

Can Cheapflights find flights from Panama City to Guayaquil with no change fees?

Yes, we can. To see specific flights from Panama City to Guayaquil with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Panama City to Guayaquil become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Guayaquil from Panama City today and book when prices fit your budget.

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Cheap flights from Panama City to Guayaquil from £172

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Panama City to Guayaquil

Cheapest flights from Panama City to GuayaquilExplore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 September 2026.

Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 September 2026.

Best flights from Panama City to GuayaquilDiscover carefully curated flight deals from Panama City to Guayaquil that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 21 September 2026.

Discover carefully curated flight deals from Panama City to Guayaquil that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 21 September 2026.

Direct flights from Panama City to GuayaquilExplore direct flight options from Panama City to Guayaquil based on user searches, and compare prices and availability for your desired travel dates. Data last updated 21 September 2026.

Explore direct flight options from Panama City to Guayaquil based on user searches, and compare prices and availability for your desired travel dates. Data last updated 21 September 2026.

Last-minute flights from Panama City to GuayaquilDiscover last-minute flight deals from Panama City to Guayaquil. Data last updated 21 September 2026 and is based on user searches.

Discover last-minute flight deals from Panama City to Guayaquil. Data last updated 21 September 2026 and is based on user searches.

One-way flights from Panama City to GuayaquilSearch for one-way flight options from Panama City to Guayaquil. Find affordable one-way fares based on user searches. Data last updated 21 September 2026.

Search for one-way flight options from Panama City to Guayaquil. Find affordable one-way fares based on user searches. Data last updated 21 September 2026.

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Use the filters below to find and compare flights from Panama City to Guayaquil that are best for you.

Best time to book a flight from Panama City to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Panama City with our price prediction graph.

Cheapflights Insights

How far ahead should I book a flight from Panama City to Guayaquil?

Booking 78 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Guayaquil?

What is the cheapest time of day to fly from PTY to GYE?

When flying from Panama City to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Panama City to Guayaquil?

Airfare is typical for this route at the moment.

Panama City to Guayaquil flights typically cost between £192 and £328 in October.The cheapest return price found within the last 5 days was £311 on Copa Airlines (5 Oct–12 Oct).

Weekly flight availability from Panama City to Guayaquil

The most flights from PTY to GYE are scheduled on a Monday (15 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (11 on average).

How often are flights from Panama City to Guayaquil delayed?

About 7% of weekly flights between Panama City and Guayaquil have experienced delays in the past year, with the average delay time being 100 minutes.

What is the most punctual flight time for Panama City to Guayaquil flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Wednesday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama City to Guayaquil flights?

Over the past year, Copa Airlines have had the lowest number of delays on this route, with just 7% of flights being delayed.

Related info for your journey

How popular is this Panama City to Guayaquil flight route?

How long is the flight from Panama City to Guayaquil?

What are the most reliable airlines from Panama City to Guayaquil?

Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?

How can I find direct flights from Panama City to Guayaquil?

Can I find deals for business class flights from Panama City to Guayaquil?

What is the cheapest month to book a flight from Panama City to Guayaquil?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

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Other flights to Guayaquil

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Can Cheapflights find flights from Panama City to Guayaquil with no change fees?

Can Cheapflights notify me if prices for flights from Panama City to Guayaquil become cheaper?

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Cheapest flights from Panama City to Guayaquil
Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 September 2026.

Best flights from Panama City to Guayaquil
Discover carefully curated flight deals from Panama City to Guayaquil that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 21 September 2026.

Direct flights from Panama City to Guayaquil
Explore direct flight options from Panama City to Guayaquil based on user searches, and compare prices and availability for your desired travel dates. Data last updated 21 September 2026.

Last-minute flights from Panama City to Guayaquil
Discover last-minute flight deals from Panama City to Guayaquil. Data last updated 21 September 2026 and is based on user searches.

One-way flights from Panama City to Guayaquil
Search for one-way flight options from Panama City to Guayaquil. Find affordable one-way fares based on user searches. Data last updated 21 September 2026.

Panama City to Guayaquil flights typically cost between £192 and £328 in October.
The cheapest return price found within the last 5 days was £311 on Copa Airlines (5 Oct–12 Oct).