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Cheap flights from Southampton to Key Largo from £458

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — MIA
17 Dec — 24 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Key Largo

Keep the following information in mind while searching for Southampton to Key Largo flight deals. Data was last updated 17 November 2025.

Round-trip from

£458

Popular in

February

Cheapest in

October

Average price

£871
Delta
  • Delta
  • 7/3-11/3
  • 4 total stops
  • 49h 20m total
  • Southampton to Key Largo
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£28 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease (£39 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Southampton to Key Largo

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Key Largo
Explore the most affordable flight options available from Southampton to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 November 2025.

Fri 5/1217:30SOU - MIA
2 stops34h 53mDelta
Mon 8/1217:20MIA - SOU
2 stops33h 50mDelta
Deal found 16/11£483
Sat 22/1109:25SOU - MIA
2 stops18h 52mDelta
Sat 29/1107:15MIA - SOU
2 stops20h 35mDelta
Deal found 17/11£486
Wed 31/1208:40SOU - MIA
2 stops20h 51mVirgin Atlantic
Wed 7/108:05MIA - SOU
2 stops19h 20mVirgin Atlantic
Deal found 16/11£599
Tue 16/1208:40SOU - MIA
2 stops18h 10mDelta
Wed 31/1211:45MIA - SOU
2 stops15h 35mDelta
Deal found 16/11£612
Mon 22/1208:40SOU - MIA
2 stops21h 08mDelta
Wed 31/1210:34MIA - SOU
2 stops16h 46mDelta
Deal found 16/11£802
Tue 30/1220:10SOU - MIA
2 stops28h 50mMultiple Airlines
Tue 6/112:02MIA - SOU
2 stops18h 53mMultiple Airlines
Deal found 15/11£818
Tue 16/1208:40SOU - MIA
2 stops18h 10mDelta
Mon 29/1207:25MIA - SOU
2 stops19h 45mDelta
Deal found 16/11£860
Fri 5/1209:30SOU - MIA
1 stop12h 40mBritish Airways
Mon 8/1222:00MIA - SOU
2 stops15h 30mBritish Airways
Deal found 16/11£873
Mon 22/1218:05SOU - MIA
1 stop25h 45mDelta
Tue 30/1218:23MIA - SOU
2 stops32h 57mDelta
Deal found 16/11£876

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 November 2025.
Use the filters below to find and compare flights from Southampton to Key Largo that are best for you.

Fly from

Southampton

Fly to

Key Largo

Route

Depart

Return

Price

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 7/3

09:25-23:20

2 stops18h 55m

Miami

Wed 11/3

07:00-17:25

2 stops30h 25m

£458

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 5/12

17:30-21:50

2 stops33h 20m

Miami

Mon 8/12

11:23-17:00

2 stops24h 37m

£483

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 8/1

17:35-23:20

2 stops34h 45m

Miami

Mon 12/1

11:39-08:50

2 stops16h 11m

£487

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 10/1

09:25-23:20

2 stops18h 55m

Miami

Mon 12/1

12:02-08:50

2 stops15h 48m

£487

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 8/1

17:35-23:20

2 stops34h 45m

Miami

Tue 13/1

16:50-17:05

1 stop19h 15m

£490

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 9/1

17:35-23:20

2 stops34h 45m

Miami

Thu 15/1

12:02-08:25

2 stops15h 23m

£490

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 10/1

09:25-23:20

2 stops18h 55m

Miami

Thu 15/1

07:40-08:25

2 stops19h 45m

£490

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 9/1

17:35-19:16

2 stops30h 41m

Miami

Tue 13/1

11:39-08:50

2 stops16h 11m

£490

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 10/1

09:25-23:20

2 stops18h 55m

Miami

Fri 16/1

20:25-17:15

2 stops39h 50m

£490

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 8/1

17:35-23:20

2 stops34h 45m

Miami

Fri 16/1

07:40-08:45

2 stops20h 05m

£490

Flights are sorted by cheapest return flights first.

Deals found on 16/11

Showing 1-10 of 19 results
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Best time to book a flight from Southampton to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Key Largo

What is the cheapest month to book a flight from Southampton to Key Largo?

Currently, May is the cheapest month in which you can book a flight from Southampton to Key Largo (average of £234). Flying from Southampton to Key Largo in July is currently the most expensive (average of £359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Key Largo?

    Southampton Eastleigh (SOU), located 3.5 mi from the city center, is the airport you fly out of when you book flights from Southampton to Key Largo. 0 airlines have flights from Eastleigh to Key Largo on a regular basis. Booking flights from Southampton Eastleigh to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Southampton to Key Largo?

    A quick flight from Southampton to Key Largo can take about 18h 55m. Delta provides one of the quickest options available for as low as £458. There are 4381 mi between Southampton and Key Largo.

  • Can I find deals for flights from Southampton to Key Largo that include hotel bookings?

    Yes. In addition to deals on Southampton to Key Largo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Key Largo.

  • Can I find deals for business class flights from Southampton to Key Largo?

    Yes. Cheapflights offers flight deals from Southampton to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Key Largo?

    Currently, May is the cheapest month in which you can book a flight from Southampton to Key Largo (average of £234). Flying from Southampton to Key Largo in July is currently the most expensive (average of £359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to Key Largo?

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Why should you use Cheapflights to find cheap flight tickets from Southampton to Key Largo?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Key Largo for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Key Largo with no change fees?

Yes, we can. To see specific flights from Southampton to Key Largo with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Southampton to Key Largo become cheaper?

Yes! Start tracking prices for Southampton to Key Largo flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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