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Cheap flights from Southampton to Key Largo from £558

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 30/3. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — MIA
23 Apr — 30 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Key Largo

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Key Largo
Explore the most affordable flight options available from Southampton to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 March 2026.

Tue 5/509:05
SOU
-
MIA
2 stops19h 24m
KLM
Tue 12/511:58
MIA
-
SOU
2 stops15h 37m
KLM
Deal found 22/3£640
Wed 6/509:05
SOU
-
MIA
2 stops19h 24m
Delta
Wed 13/507:12
MIA
-
SOU
2 stops20h 23m
Delta
Deal found 22/3£655
Wed 6/509:05
SOU
-
MIA
1 stop34h 40m
KLM
Wed 13/511:37
MIA
-
SOU
2 stops15h 58m
KLM
Deal found 22/3£684
Fri 1/517:20
SOU
-
MIA
1 stop26h 25m
KLM
Fri 8/507:12
MIA
-
SOU
2 stops20h 33m
KLM
Deal found 20/3£710
Mon 21/919:55
SOU
-
MIA
2 stops23h 35m
British Airways
Mon 12/1017:00
MIA
-
SOU
2 stops16h 45m
British Airways
Deal found 23/3£713
Fri 8/509:05
SOU
-
MIA
2 stops19h 19m
Delta
Fri 15/507:12
MIA
-
SOU
2 stops20h 33m
Delta
Deal found 23/3£716
Mon 20/419:55
SOU
-
MIA
2 stops23h 40m
British Airways
Mon 11/517:00
MIA
-
SOU
2 stops16h 45m
British Airways
Deal found 23/3£719
Thu 7/509:05
SOU
-
MIA
2 stops19h 19m
Delta
Thu 14/507:12
MIA
-
SOU
2 stops20h 23m
Delta
Deal found 23/3£719
Tue 22/919:55
SOU
-
MIA
2 stops23h 35m
British Airways
Tue 13/1022:40
MIA
-
SOU
2 stops15h 45m
British Airways
Deal found 24/3£736

Find flight deals from Southampton to Key Largo

Keep the following information in mind while searching for Southampton to Key Largo flight deals. Data was last updated 24 March 2026.

Round-trip from

£640

One-way from

£558

Popular in

December

Cheapest in

September

Average price

£531
KLM
  • KLM
  • 5/5-12/5
  • 4 total stops
  • 35h 01m total
  • Southampton to Key Largo
Search Deals
Aer Lingus
  • Aer Lingus
  • 30/3
  • 2 total stops
  • 33h 03m total
  • Southampton to Key Largo
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£12 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 March 2026.
Use the filters below to find and compare flights from Southampton to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 6/5

09:05-23:29

2 stops19h 24m

Miami

Wed 13/5

07:12-08:35

2 stops20h 23m

£655

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Wed 6/5

09:05-14:45

1 stop34h 40m

Miami

Wed 13/5

11:37-08:35

2 stops15h 58m

£684

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 8/5

09:05-23:24

2 stops19h 19m

Miami

Fri 15/5

07:12-08:45

2 stops20h 33m

£716

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 20/4

19:55-14:35

2 stops23h 40m

Miami

Mon 11/5

17:00-14:45

2 stops16h 45m

£719

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 8/5

20:00-20:25

2 stops29h 25m

Miami

Fri 15/5

15:59-16:50

2 stops19h 51m

£767

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 23/4

15:15-20:20

2 stops34h 05m

Miami

Mon 27/4

22:45-08:25

2 stops28h 40m

£769

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 18/9

19:55-14:30

2 stops23h 35m

Miami

Fri 9/10

17:00-14:25

2 stops16h 25m

£837

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 5/5

09:05-14:30

3 stops34h 25m

Miami

Tue 12/5

17:00-19:30

2 stops21h 30m

£871

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 30/5

19:40-16:55

2 stops50h 15m

Miami

Mon 29/6

19:40-19:00

2 stops18h 20m

£898
Fastest return journey

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 1/6

19:55-14:30

2 stops23h 35m

Miami

Mon 29/6

22:40-19:25

2 stops15h 45m

£905

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Southampton to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Key Largo

What is the cheapest month to book a flight from Southampton to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Southampton to Key Largo (average of £241). Flying from Southampton to Key Largo in January is currently the most expensive (average of £360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Key Largo?

    Southampton Eastleigh (SOU), located 3.5 mi from the city center, is the airport you fly out of when you book flights from Southampton to Key Largo. 0 airlines have flights from Eastleigh to Key Largo on a regular basis. Booking flights from Southampton Eastleigh to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Southampton to Key Largo?

    A quick flight from Southampton to Key Largo can take about 19h 24m. Delta provides one of the quickest options available for as low as £655. There are 4381 mi between Southampton and Key Largo. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Key Largo that include hotel bookings?

    Yes. In addition to deals on Southampton to Key Largo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Key Largo.

  • Can I find deals for business class flights from Southampton to Key Largo?

    Yes. Cheapflights offers flight deals from Southampton to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Southampton to Key Largo (average of £241). Flying from Southampton to Key Largo in January is currently the most expensive (average of £360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to Key Largo?

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Why should you use Cheapflights to find cheap flight tickets from Southampton to Key Largo?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to Key Largo for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to Key Largo with no change fees?

Yes, we can. To see specific flights from Southampton to Key Largo with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Southampton to Key Largo become cheaper?

Yes! Start tracking prices for Southampton to Key Largo flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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