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Cheap flights from Southampton to Key Largo from £387

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/9. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — MIA
14 Sep — 21 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Key Largo

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Key Largo
Explore the most affordable flight options available from Southampton to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 August 2026.

Thu 10/920:00 -
2 stops29h 05m
Wed 16/916:55 -
2 stops18h 55m
Deal found 10/8£515
Fri 4/917:20 -
2 stops31h 45m
Tue 8/915:00 -
2 stops23h 30m
Deal found 14/8£640
Mon 28/909:05 -
1 stop34h 40m
Mon 5/1018:42 -
2 stops17h 08m
Deal found 13/8£646
Fri 4/917:20 -
1 stop26h 25m
Tue 8/918:42 -
2 stops17h 08m
Deal found 14/8£660
Fri 6/1108:40 -
2 stops17h 41m
Mon 16/1117:45 -
2 stops18h 15m
Deal found 12/8£665
Mon 5/1009:05 -
2 stops17h 05m
Wed 4/1108:00 -
2 stops19h 10m
Deal found 13/8£706
Sun 4/1009:15 -
2 stops19h 00m
Wed 4/1111:47 -
2 stops15h 23m
Deal found 13/8£707
Fri 9/1009:05 -
2 stops30h 47m
Thu 29/1013:19 -
2 stops14h 51m
Deal found 13/8£716
Sat 10/1017:20 -
2 stops34h 36m
Mon 2/1111:47 -
2 stops15h 23m
Deal found 13/8£726
Wed 4/1109:20 -
1 stop12h 50m
Wed 18/1119:05 -
1 stop16h 30m
Deal found 12/8£754
Sat 24/1017:20 -
1 stop29h 50m
Wed 18/1119:05 -
1 stop19h 25m
Deal found 10/8£761

Find flight deals from Southampton to Key Largo

Keep the following information in mind while searching for Southampton to Key Largo flight deals. Data was last updated 15 August 2026.

Round-trip from

£515

One-way from

£387

Popular in

August

Cheapest in

January

Average price

£630
Aer Lingus
  • Aer Lingus
  • 10/9-16/9
  • 4 total stops
  • 48h 00m total
  • Southampton to Key Largo
Search Deals
26/9
  • 26/9
  • 3 total stops
  • 40h 55m total
  • Southampton to Key Largo
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£14 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£6 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 August 2026.
Use the filters below to find and compare flights from Southampton to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Wed 7/10

17:20-16:45

2 stops28h 25m

Miami

Wed 4/11

18:25-17:00

2 stops17h 35m

£706

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Fri 9/10

09:05-10:52

2 stops30h 47m

Miami

Sat 31/10

08:00-08:55

2 stops20h 55m

£716

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Fri 9/10

09:05-10:52

2 stops30h 47m

Miami

Thu 29/10

13:19-08:10

2 stops14h 51m

£716

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Sat 24/10

17:20-18:10

1 stop29h 50m

Miami

Wed 18/11

17:10-14:45

2 stops16h 35m

£776

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Thu 26/11

17:05-17:10

1 stop29h 05m

Miami

Sun 6/12

22:00-19:25

2 stops16h 25m

£791

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Sat 21/11

17:05-17:10

1 stop29h 05m

Miami

Wed 25/11

19:05-16:35

1 stop16h 30m

£792

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Fri 13/11

09:20-17:10

1 stop12h 50m

Miami

Fri 4/12

19:05-08:40

1 stop32h 35m

£809
Fastest return journey

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Wed 10/2

09:20-17:10

1 stop12h 50m

Miami

Wed 3/3

22:00-19:25

2 stops16h 25m

£818

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Fri 11/12

09:20-17:10

1 stop12h 50m

Miami

Sun 27/12

19:05-08:40

1 stop32h 35m

£824
Cheapest one-way
Fastest single journey

SouthamptonMiami

SOU Southampton Eastleigh - MIA Miami

SOUMIA

Southampton Eastleigh

Wed 25/11

09:20-17:10

1 stop12h 50m

£480

Flights are sorted by cheapest return flights first.

Deals found on 12/8

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Southampton to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Key Largo

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Key Largo?

    Southampton Eastleigh (SOU), located 3.5 mi from the city center, is the airport you fly out of when you book flights from Southampton to Key Largo. 0 airlines have flights from Eastleigh to Key Largo on a regular basis. Booking flights from Southampton Eastleigh to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Southampton to Key Largo?

    A quick flight from Southampton to Key Largo can take about 28h 25m. Delta provides one of the quickest options available for as low as £706. There are 4381 mi between Southampton and Key Largo. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Key Largo that include hotel bookings?

    Yes. In addition to deals on Southampton to Key Largo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Key Largo.

  • Can I find deals for business class flights from Southampton to Key Largo?

    Yes. Cheapflights offers flight deals from Southampton to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to Key Largo?

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Why should you use Cheapflights to find cheap flight tickets from Southampton to Key Largo?

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Can Cheapflights find flights from Southampton to Key Largo with no change fees?

Yes, we can. To see specific flights from Southampton to Key Largo with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Southampton to Key Largo become cheaper?

Yes! Start tracking prices for Southampton to Key Largo flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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