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Cheap flights from Iowa to Manchester from £321

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAN
6 Dec — 13 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Iowa to Manchester

Keep the following information in mind while searching for Iowa to Manchester flight deals. Data was last updated 6 November 2025.

Round-trip from

£476

One-way from

£321

Popular in

June

Cheapest in

September

Average price

£605
Delta
  • Delta
  • 14/1-18/1
  • 2 total stops
  • 26h 45m total
  • Iowa to Manchester
Search Deals
United Airlines
  • United Airlines
  • 17/1
  • 2 total stops
  • 14h 35m total
  • Iowa to Manchester
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£69 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£18 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
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Find flight deals from Iowa to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Iowa to Manchester
Explore the most affordable flight options available from Iowa to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 November 2025.

Fri 28/1115:17OMA - MAN
2 stops13h 03mUnited Airlines
Mon 8/1206:00MAN - OMA
2 stops38h 19mUnited Airlines
Deal found 5/11£628
Wed 19/1110:21DSM - MAN
2 stops24h 14mDelta
Sun 23/1109:05MAN - DSM
1 stop14h 41mDelta
Deal found 5/11£630
Wed 19/1113:05DSM - MAN
2 stops15h 15mUnited Airlines
Mon 24/1106:10MAN - DSM
2 stops21h 22mUnited Airlines
Deal found 4/11£635
Fri 14/1114:17DSM - MAN
1 stop14h 13mVirgin Atlantic
Tue 18/1113:30MAN - DSM
1 stop15h 03mVirgin Atlantic
Deal found 4/11£699
Sat 15/1111:28DSM - MAN
2 stops25h 07mScandinavian Airlines
Wed 19/1119:15MAN - DSM
2 stops33h 18mScandinavian Airlines
Deal found 3/11£700
Fri 14/1114:45DSM - MAN
2 stops13h 45mDelta
Tue 18/1113:00MAN - DSM
2 stops26h 41mDelta
Deal found 4/11£702
Wed 19/1108:02DSM - MAN
3 stops20h 18mAir Canada
Mon 24/1106:10MAN - DSM
3 stops21h 22mAir Canada
Deal found 5/11£703
Wed 19/1114:17DSM - MAN
1 stop14h 13mVirgin Atlantic
Sun 23/1109:05MAN - DSM
1 stop19h 28mVirgin Atlantic
Deal found 5/11£779
Wed 19/1114:17DSM - MAN
1 stop14h 13mDelta
Mon 24/1105:50MAN - DSM
2 stops21h 25mDelta
Deal found 5/11£787
Fri 19/1215:43OMA - MAN
2 stops16h 37mAmerican Airlines
Fri 26/1207:50MAN - OMA
2 stops16h 53mAmerican Airlines
Deal found 3/11£1,342
Fri 19/1207:00OMA - MAN
2 stops19h 20mDelta
Fri 26/1213:25MAN - OMA
1 stop13h 46mDelta
Deal found 3/11£1,362
Sat 20/1218:20OMA - MAN
2 stops34h 00mUnited Airlines
Sat 27/1206:10MAN - OMA
2 stops21h 48mUnited Airlines
Deal found 5/11£1,465

Cheapflights Fare Finder

 
Customise your flight search to find flights from Iowa to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 6 November 2025.
Use the filters below to find and compare flights from Iowa to Manchester that are best for you.

Fly from

Iowa

Fly to

Manchester

Route

Depart

Return

Price

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 21/1

11:26-10:30

1 stop17h 04m

Manchester

Sun 25/1

13:00-22:31

1 stop15h 31m

£476

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 16/1

11:26-10:30

1 stop17h 04m

Manchester

Tue 20/1

13:30-22:31

1 stop15h 01m

£476

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 14/1

17:16-10:30

1 stop11h 14m

Manchester

Sun 18/1

13:00-22:31

1 stop15h 31m

£476

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Wed 21/1

12:25-10:30

2 stops16h 05m

Manchester

Sun 25/1

13:00-22:31

1 stop15h 31m

£479

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 13/2

17:15-10:30

1 stop11h 15m

Manchester

Sat 21/2

05:50-21:19

2 stops21h 29m

£483

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Fri 16/1

17:16-10:30

1 stop11h 14m

Manchester

Tue 20/1

09:05-09:41

2 stops30h 36m

£483

Cedar RapidsManchester

CID - MAN

CIDMAN

Cedar Rapids

Fri 27/3

13:10-10:20

2 stops16h 10m

Manchester

Tue 31/3

07:00-16:54

2 stops15h 54m

£594

OmahaManchester

OMA - MAN

OMAMAN

Omaha Eppley Airfield

Fri 27/3

11:21-17:00

2 stops24h 39m

Manchester

Tue 31/3

06:05-20:25

2 stops20h 20m

£612

OmahaManchester

OMA - MAN

OMAMAN

Omaha Eppley Airfield

Fri 28/11

13:05-10:20

2 stops15h 15m

Manchester

Mon 8/12

13:00-17:29

2 stops34h 29m

£628

OmahaManchester

OMA - MAN

OMAMAN

Omaha Eppley Airfield

Fri 27/3

11:05-10:30

1 stop18h 25m

Manchester

Tue 31/3

11:00-00:01

1 stop19h 01m

£632

Flights are sorted by cheapest return flights first.

Deals found on 4/11

Showing 1-10 of 23 results
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Best time to book a flight from Iowa to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Iowa with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Manchester

What is the cheapest month to book a flight from Iowa to Manchester?

Currently, September is the cheapest month in which you can book a flight from Iowa to Manchester (average of £500). Flying from Iowa to Manchester in June is currently the most expensive (average of £1,023). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Iowa?

    For a flight from Iowa to Manchester, you will be flying into Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Iowa to Manchester?

    For as low as £594, Delta can have you in Manchester from Iowa in 16h 10m. There are 3957 mi between Iowa and Manchester. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Manchester?

    The most popular route from Iowa to Manchester is Des Moines - Manchester. You may also consider Omaha Eppley Airfield - Manchester or Cedar Rapids - Manchester.

  • Can I find deals for flights from Iowa to Manchester that include hotel bookings?

    Yes. In addition to deals on Iowa to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Manchester.

  • Can I find deals for business class flights from Iowa to Manchester?

    Yes. Cheapflights offers flight deals from Iowa to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Manchester?

    Currently, September is the cheapest month in which you can book a flight from Iowa to Manchester (average of £500). Flying from Iowa to Manchester in June is currently the most expensive (average of £1,023). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Derby
Bradford
Harrogate
Otley
Preston
Southport
Blackburn
Stoke-on-Trent
Lancaster
Bolton
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Morecambe
Stockport
Telford
Rochdale
Warrington
Huddersfield

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How does Cheapflights help users find flights from Iowa to Manchester?

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