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Cheap flights from Knoxville to Manchester from £547

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
31 Aug — 7 Sep1
1 adult

Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 26 August 2025.

Round-trip from

£547

Popular in

June

Cheapest in

November

Average price

£575
Virgin Atlantic
  • Virgin Atlantic
  • 5/12-12/12
  • 3 total stops
  • 29h 41m total
  • Knoxville to Manchester
Search Deals
Highest demand for flights based on searches. 14% potential increase in price (£88 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£23 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 August 2025.

Fri 5/1218:10TYS - MAN
1 stop11h 20mVirgin Atlantic
Fri 12/1210:25MAN - TYS
2 stops18h 21mVirgin Atlantic
Deal found 24/8£547
Fri 5/1218:10TYS - MAN
1 stop11h 20mDelta
Fri 12/1213:25MAN - TYS
1 stop26h 03mDelta
Deal found 24/8£548
Wed 8/1009:55TYS - MAN
2 stops26h 25mUnited Airlines
Wed 15/1009:10MAN - TYS
2 stops19h 33mUnited Airlines
Deal found 24/8£554
Fri 5/1215:40TYS - MAN
2 stops17h 40mAmerican Airlines
Fri 12/1208:05MAN - TYS
2 stops17h 51mAmerican Airlines
Deal found 24/8£578
Sat 13/919:25TYS - MAN
2 stops33h 25mUnited Airlines
Sat 27/911:50MAN - TYS
2 stops40h 53mUnited Airlines
Deal found 25/8£598
Tue 16/1210:05TYS - MAN
2 stops19h 05mDelta
Fri 9/113:00MAN - TYS
2 stops26h 30mDelta
Deal found 24/8£626
Fri 10/1010:51TYS - MAN
2 stops16h 34mUnited Airlines
Sat 25/1006:05MAN - TYS
2 stops21h 45mUnited Airlines
Deal found 24/8£628
Fri 10/1020:37TYS - MAN
2 stops15h 43mAmerican Airlines
Sat 25/1007:00MAN - TYS
2 stops15h 32mAmerican Airlines
Deal found 25/8£631
Sun 14/1218:10TYS - MAN
2 stops34h 20mScandinavian Airlines
Thu 8/119:15MAN - TYS
2 stops33h 29mScandinavian Airlines
Deal found 24/8£660
Sun 14/1218:10TYS - MAN
2 stops34h 20mScandinavian Airlines
Sun 11/119:15MAN - TYS
2 stops33h 29mScandinavian Airlines
Deal found 24/8£697

Cheapflights Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 26 August 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 5/12

18:10-10:30

1 stop11h 20m

Manchester

Fri 12/12

10:25-23:46

2 stops18h 21m

£547

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 5/12

18:10-10:30

1 stop11h 20m

Manchester

Fri 12/12

13:25-10:28

1 stop26h 03m

£548

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 8/10

09:55-17:20

2 stops26h 25m

Manchester

Wed 15/10

09:10-23:43

2 stops19h 33m

£554

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 5/12

15:40-14:20

2 stops17h 40m

Manchester

Fri 12/12

08:05-20:56

2 stops17h 51m

£578

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 13/9

19:25-09:50

2 stops33h 25m

Manchester

Sat 27/9

11:50-23:43

2 stops40h 53m

£598

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 16/12

10:05-10:10

2 stops19h 05m

Manchester

Fri 9/1

13:00-10:30

2 stops26h 30m

£626

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 10/10

10:51-08:25

2 stops16h 34m

Manchester

Sat 25/10

06:05-22:50

2 stops21h 45m

£628

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 10/10

20:37-17:20

2 stops15h 43m

Manchester

Sat 25/10

07:00-17:32

2 stops15h 32m

£631

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sun 14/12

18:10-09:30

2 stops34h 20m

Manchester

Thu 8/1

19:15-23:44

2 stops33h 29m

£660

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sun 14/12

18:10-09:30

2 stops34h 20m

Manchester

Sun 11/1

19:15-23:44

2 stops33h 29m

£697

Flights are sorted by cheapest return flights first.

Deals found on 24/8

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £117). Flying from Knoxville to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester?

    A quick flight from Knoxville to Manchester can take about 11h 20m. Virgin Atlantic provides one of the quickest options available for as low as £547. There are 3961 mi between Knoxville and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £117). Flying from Knoxville to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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