Find flights
When to book
FAQs

Cheap flights from Knoxville to Manchester from £579

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
16 Nov — 23 Nov1
1 adult
1 adult, Economy

Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 17 October 2025.

Round-trip from

£579

Popular in

June

Cheapest in

November

Average price

£567
United Airlines
  • United Airlines
  • 27/3-31/3
  • 4 total stops
  • 36h 24m total
  • Knoxville to Manchester
Search Deals
Highest demand for flights based on searches. 15% potential increase in price (£93 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Knoxville to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 October 2025.

Mon 1/1205:45TYS - MAN
2 stops23h 35mUnited Airlines
Wed 31/1206:00MAN - TYS
2 stops40h 00mUnited Airlines
Deal found 16/10£720
Mon 22/1219:01TYS - MAN
2 stops15h 09mAmerican Airlines
Sun 11/108:55MAN - TYS
2 stops17h 01mAmerican Airlines
Deal found 15/10£775
Mon 22/1208:25TYS - MAN
2 stops20h 45mDelta
Sun 11/113:00MAN - TYS
1 stop15h 44mDelta
Deal found 15/10£787
Fri 26/1207:15TYS - MAN
3 stops31h 00mMultiple Airlines
Sun 4/106:00MAN - TYS
2 stops33h 15mMultiple Airlines
Deal found 16/10£946
Mon 1/1220:07TYS - MAN
2 stops14h 58mDelta
Wed 31/1213:30MAN - TYS
1 stop28h 50mDelta
Deal found 16/10£977
Fri 19/1208:30TYS - MAN
1 stop21h 00mDelta
Wed 7/113:30MAN - TYS
1 stop12h 08mDelta
Deal found 16/10£1,041
Fri 19/1218:25TYS - MAN
2 stops14h 00mAmerican Airlines
Wed 7/108:05MAN - TYS
2 stops17h 51mAmerican Airlines
Deal found 16/10£1,141

Cheapflights Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 October 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

09:40-10:20

2 stops20h 40m

Manchester

Tue 31/3

06:05-16:49

2 stops15h 44m

£579

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

16:00-10:30

1 stop14h 30m

Manchester

Tue 31/3

11:00-23:44

1 stop17h 44m

£693

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

05:45-10:20

2 stops23h 35m

Manchester

Wed 31/12

06:00-17:00

2 stops40h 00m

£720

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 22/12

19:01-15:10

2 stops15h 09m

Manchester

Sun 11/1

08:55-20:56

2 stops17h 01m

£775

Flights are sorted by cheapest return flights first.

Deals found on 14/10

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £472). Flying from Knoxville to Manchester in June is currently the most expensive (average of £739). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester?

    A quick flight from Knoxville to Manchester can take about 14h 30m. United Airlines provides one of the quickest options available for as low as £693. There are 3961 mi between Knoxville and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Manchester (average of £472). Flying from Knoxville to Manchester in June is currently the most expensive (average of £739). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Preston
Stoke-on-Trent
Southport
Blackburn
Wakefield
Stockport
Lancaster
Morecambe
Bolton
Telford
Rochdale
Huddersfield
Salford
Warrington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Knoxville to Manchester?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Manchester from Knoxville today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Knoxville to Manchester?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Manchester from Knoxville.

Can Cheapflights find flights from Knoxville to Manchester with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Knoxville to Manchester flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Knoxville to Manchester become cheaper?

Not ready to book yet? You can track prices for flights from Knoxville to Manchester on Cheapflights with our Price Alert feature and get notified when better prices are available.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.