Cheap flights from Panama to Manchester from £455

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
30 Dec — 6 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to Manchester

Keep the following information in mind while searching for Panama to Manchester flight deals. Data was last updated 30 November 2025.

Round-trip from

£727

One-way from

£455

Popular in

September

Cheapest in

July

Average price

£984
Iberia
  • Iberia
  • 26/1-10/2
  • 2 total stops
  • 45h 45m total
  • Panama to Manchester
17/12
  • 17/12
  • 3 total stops
  • 24h 35m total
  • Panama to Manchester
Highest demand for flights based on searches. 16% potential increase in price (£155 potential increase over avg. return price).
Cheapest flight prices on average. 9% potential price decrease (£66 potential savings vs. average return price).
Average for round-trip flights in November 2025

Find flight deals from Panama to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama to Manchester
Explore the most affordable flight options available from Panama to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 November 2025.

Tue 9/1210:00PTY - MAN
2 stops21h 20mUnited Airlines
Sun 21/1206:00MAN - PTY
2 stops43h 27mUnited Airlines
Deal found 28/11£1,302
Tue 9/1210:00PTY - MAN
2 stops21h 20mUnited Airlines
Sat 20/1213:00MAN - PTY
2 stops50h 33mUnited Airlines
Deal found 28/11£1,316
Tue 9/1221:30PTY - MAN
1 stop15h 10mMultiple Airlines
Sat 20/1217:15MAN - PTY
2 stops43h 51mMultiple Airlines
Deal found 28/11£1,337
Tue 9/1221:30PTY - MAN
1 stop15h 10mMultiple Airlines
Sun 21/1218:05MAN - PTY
2 stops43h 35mMultiple Airlines
Deal found 28/11£1,340
Wed 10/1216:41PTY - MAN
2 stops43h 19mUnited Airlines
Sun 21/1206:00MAN - PTY
2 stops43h 27mUnited Airlines
Deal found 28/11£1,360
Wed 10/1216:41PTY - MAN
2 stops43h 19mUnited Airlines
Sat 20/1213:00MAN - PTY
2 stops60h 27mUnited Airlines
Deal found 28/11£1,375
Thu 11/1219:20PTY - MAN
2 stops34h 00mUnited Airlines
Sun 21/1206:00MAN - PTY
2 stops40h 08mUnited Airlines
Deal found 28/11£1,411
Tue 9/1210:00PTY - MAN
2 stops21h 20mUnited Airlines
Fri 19/1206:05MAN - PTY
2 stops36h 55mUnited Airlines
Deal found 28/11£1,419
Thu 11/1218:45PTY - MAN
1 stop34h 25mMultiple Airlines
Fri 19/1213:25MAN - PTY
1 stop35h 35mMultiple Airlines
Deal found 28/11£1,422
Thu 11/1218:45PTY - MAN
1 stop20h 20mKLM
Sun 21/1217:25MAN - PTY
1 stop28h 05mKLM
Deal found 28/11£1,422

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 November 2025.
Use the filters below to find and compare flights from Panama to Manchester that are best for you.

Fly from

Panama

Fly to

Manchester

Route

Depart

Return

Price

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 26/1

18:20-17:40

1 stop18h 20m

Manchester

Tue 10/2

18:20-16:45

1 stop27h 25m

£727

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 23/1

15:20-10:30

1 stop14h 10m

Manchester

Sun 8/2

11:00-16:30

1 stop34h 30m

£755

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 11/2

22:05-08:20

1 stop29h 15m

Manchester

Sun 15/2

17:25-16:30

1 stop28h 05m

£755

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 28/2

21:45-09:50

1 stop31h 05m

Manchester

Fri 24/4

23:25-20:20

1 stop26h 55m

£811

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Thu 5/2

09:48-15:50

2 stops49h 02m

Manchester

Mon 9/2

16:50-09:04

3 stops45h 14m

£1,248

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 17/12

09:45-15:20

3 stops24h 35m

£455

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 17/1

22:29-10:20

2 stops30h 51m

£594

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 17/12

21:45-09:50

1 stop31h 05m

£598

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 26/1

11:25-10:45

3 stops42h 20m

£993

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 27/1

14:55-10:45

3 stops38h 50m

£1,055

Flights are sorted by cheapest return flights first.

Deals found on 29/11

Showing 1-10 of 11 results
1
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Best time to book a flight from Panama to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Manchester
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Manchester from Panama?

    Manchester (MAN) is the airport you will fly into if you book a flight from Panama to Manchester. It is only a 8.9 mi journey from Manchester (MAN) to Manchester’s city center.

  • How long is the flight from Panama to Manchester?

    Iberia, KLM, and Turkish Airlines can get you from Panama to Manchester in just under 18h 20m. Your travel time can differ by up to 30h 42m. The distance between Panama and Manchester is about 5182 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Manchester.

  • Can I find deals for business class flights from Panama to Manchester?

    Yes. Cheapflights offers flight deals from Panama to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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