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Cheap flights from Panama to Manchester from £458

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
4 May — 11 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama to Manchester
Explore the most affordable flight options available from Panama to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 April 2026.

Fri 18/915:30
PTY
-
MAN
2 stops33h 00m
United Airlines
Mon 21/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 31/3£809
Mon 13/404:25
PTY
-
MAN
3 stops30h 45m
Multiple Airlines
Thu 16/413:50
MAN
-
PTY
3 stops40h 45m
Multiple Airlines
Deal found 30/3£818
Sat 5/915:30
PTY
-
MAN
2 stops57h 00m
United Airlines
Wed 9/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 3/4£827
Mon 13/415:30
PTY
-
MAN
2 stops37h 10m
United Airlines
Thu 16/410:35
MAN
-
PTY
2 stops38h 56m
United Airlines
Deal found 30/3£828
Mon 30/315:51
PTY
-
MAN
2 stops34h 54m
Iberia
Wed 8/408:00
MAN
-
PTY
1 stop18h 00m
Iberia
Deal found 30/3£848
Sun 31/515:30
PTY
-
MAN
2 stops57h 00m
United Airlines
Sun 14/609:00
MAN
-
PTY
2 stops59h 14m
United Airlines
Deal found 1/4£880
Mon 22/609:45
PTY
-
MAN
2 stops38h 45m
United Airlines
Wed 15/709:00
MAN
-
PTY
2 stops25h 04m
United Airlines
Deal found 31/3£882
Mon 18/509:38
DAV
-
MAN
2 stops30h 47m
Multiple Airlines
Mon 25/517:35
MAN
-
DAV
3 stops56h 03m
Multiple Airlines
Deal found 3/4£1,022
Sat 16/509:38
DAV
-
MAN
2 stops44h 27m
Multiple Airlines
Sat 23/523:30
MAN
-
DAV
3 stops39h 28m
Multiple Airlines
Deal found 1/4£1,151
Mon 11/509:38
DAV
-
MAN
2 stops41h 57m
Turkish Airlines
Thu 14/517:35
MAN
-
DAV
3 stops45h 23m
Turkish Airlines
Deal found 30/3£1,156

Find flight deals from Panama to Manchester

Keep the following information in mind while searching for Panama to Manchester flight deals. Data was last updated 4 April 2026.

Round-trip from

£809

One-way from

£458

Popular in

September

Cheapest in

July

Average price

£1,064
United Airlines
  • United Airlines
  • 18/9-21/9
  • 5 total stops
  • 52h 26m total
  • Panama to Manchester
Search Deals
25/4
  • 25/4
  • 3 total stops
  • 25h 15m total
  • Panama to Manchester
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£82 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease (£60 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 April 2026.
Use the filters below to find and compare flights from Panama to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 18/9

15:30-06:30

3 stops33h 00m

Manchester

Mon 21/9

06:05-19:31

2 stops19h 26m

£809

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 5/9

15:30-06:30

2 stops57h 00m

Manchester

Wed 9/9

06:05-19:31

2 stops19h 26m

£827

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

15:30-06:30

2 stops57h 00m

Manchester

Sun 14/6

09:00-14:14

2 stops59h 14m

£880

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 18/5

09:45-10:25

2 stops18h 40m

Manchester

Fri 28/8

09:00-18:37

2 stops39h 37m

£899
Fastest return journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 25/5

09:45-10:25

2 stops18h 40m

Manchester

Thu 28/5

06:05-19:31

2 stops19h 26m

£913

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 25/6

09:45-10:25

2 stops18h 40m

Manchester

Wed 15/7

09:00-04:04

2 stops25h 04m

£916

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Mon 18/5

09:38-22:25

2 stops30h 47m

Manchester

Mon 25/5

17:35-19:38

3 stops56h 03m

£1,022

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Sat 16/5

09:38-12:05

2 stops44h 27m

Manchester

Sat 23/5

23:30-08:58

3 stops39h 28m

£1,151

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Mon 11/5

09:38-09:35

2 stops41h 57m

Manchester

Thu 14/5

17:35-08:58

3 stops45h 23m

£1,156
Cheapest one-way

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 25/4

04:25-11:40

3 stops25h 15m

£458

Flights are sorted by cheapest return flights first.

Deals found on 2/4

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Manchester
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Panama?

    Manchester (MAN) is the airport you will fly into if you book a flight from Panama to Manchester. It is only a 8.9 mi journey from Manchester (MAN) to Manchester’s city center.

  • How long is the flight from Panama to Manchester?

    United Airlines and Turkish Airlines can get you from Panama to Manchester in just under 33h. Your travel time can differ by up to 8h 57m. The distance between Panama and Manchester is about 5182 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Manchester.

  • Can I find deals for business class flights from Panama to Manchester?

    Yes. Cheapflights offers flight deals from Panama to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

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Lincoln
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Macclesfield
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