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Cheap flights from Panama to Manchester from £478

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
20 Apr — 27 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama to Manchester
Explore the most affordable flight options available from Panama to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 March 2026.

Mon 27/420:25
PTY
-
MAN
2 stops21h 15m
Multiple Airlines
Thu 21/505:45
MAN
-
PTY
3 stops24h 50m
Multiple Airlines
Deal found 20/3£671
Tue 14/404:25
PTY
-
MAN
3 stops25h 15m
Multiple Airlines
Tue 5/513:35
MAN
-
PTY
2 stops30h 40m
Multiple Airlines
Deal found 20/3£728
Wed 8/422:20
PTY
-
MAN
1 stop18h 05m
Multiple Airlines
Wed 22/406:35
MAN
-
PTY
2 stops24h 00m
Multiple Airlines
Deal found 20/3£781
Wed 15/422:20
PTY
-
MAN
1 stop18h 05m
Multiple Airlines
Wed 6/506:35
MAN
-
PTY
2 stops37h 40m
Multiple Airlines
Deal found 20/3£792
Fri 18/915:30
PTY
-
MAN
3 stops33h 00m
United Airlines
Mon 21/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 17/3£798
Wed 8/405:30
PTY
-
MAN
3 stops37h 25m
Multiple Airlines
Mon 27/418:10
MAN
-
PTY
3 stops36h 25m
Multiple Airlines
Deal found 20/3£801
Thu 7/509:38
DAV
-
MAN
2 stops30h 47m
Turkish Airlines
Mon 11/523:30
MAN
-
DAV
3 stops39h 28m
Turkish Airlines
Deal found 16/3£1,128
Fri 1/520:18
DAV
-
MAN
2 stops44h 07m
Multiple Airlines
Fri 8/523:30
MAN
-
DAV
2 stops38h 13m
Multiple Airlines
Deal found 17/3£1,140
Wed 6/509:38
DAV
-
MAN
2 stops41h 57m
Turkish Airlines
Sun 10/523:30
MAN
-
DAV
3 stops39h 28m
Turkish Airlines
Deal found 20/3£1,158

Find flight deals from Panama to Manchester

Keep the following information in mind while searching for Panama to Manchester flight deals. Data was last updated 21 March 2026.

Round-trip from

£671

One-way from

£478

Popular in

September

Cheapest in

July

Average price

£1,204
27/4-21/5
  • 27/4-21/5
  • 5 total stops
  • 46h 05m total
  • Panama to Manchester
Search Deals
12/4
  • 12/4
  • 3 total stops
  • 59h 45m total
  • Panama to Manchester
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£70 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease (£64 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 March 2026.
Use the filters below to find and compare flights from Panama to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 8/4

20:05-22:25

1 stop20h 20m

Manchester

Wed 22/4

11:00-14:15

3 stops33h 15m

£830

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 14/4

20:05-16:05

1 stop38h 00m

Manchester

Tue 5/5

17:35-20:25

1 stop32h 50m

£843

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 28/4

20:05-16:05

1 stop38h 00m

Manchester

Tue 12/5

17:35-18:25

2 stops30h 50m

£869

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

15:30-06:30

2 stops57h 00m

Manchester

Sun 14/6

09:00-14:14

2 stops35h 14m

£872

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 7/5

20:10-22:25

1 stop20h 15m

Manchester

Mon 11/5

23:30-18:25

2 stops24h 55m

£898

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 22/4

09:45-10:25

2 stops18h 40m

Manchester

Sun 26/4

10:35-19:31

2 stops38h 56m

£901

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 5/9

09:45-17:20

2 stops25h 35m

Manchester

Wed 9/9

09:00-14:14

2 stops59h 14m

£901
Fastest return journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 28/4

09:45-10:25

2 stops18h 40m

Manchester

Tue 12/5

06:05-19:31

2 stops19h 26m

£903

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Thu 7/5

09:38-22:25

2 stops30h 47m

Manchester

Mon 11/5

23:30-08:58

3 stops39h 28m

£1,128

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Fri 1/5

20:18-22:25

2 stops44h 07m

Manchester

Fri 8/5

17:35-07:43

3 stops44h 08m

£1,140

Flights are sorted by cheapest return flights first.

Deals found on 20/3

Showing 1-10 of 13 resultsSorted by cheapest first
1
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Best time to book a flight from Panama to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Manchester
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Panama?

    Manchester (MAN) is the airport you will fly into if you book a flight from Panama to Manchester. It is only a 8.9 mi journey from Manchester (MAN) to Manchester’s city center.

  • How long is the flight from Panama to Manchester?

    Turkish Airlines and United Airlines can get you from Panama to Manchester in just under 38h. Your travel time can differ by up to 19h. The distance between Panama and Manchester is about 5182 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Manchester.

  • Can I find deals for business class flights from Panama to Manchester?

    Yes. Cheapflights offers flight deals from Panama to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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