Cheap flights from Panama to Manchester from £537

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
12 Jun — 19 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama to Manchester
Explore the most affordable flight options available from Panama to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 May 2026.

Fri 18/909:45
PTY
-
MAN
2 stops38h 45m
United Airlines
Mon 21/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 11/5£749
Mon 8/620:25
PTY
-
MAN
2 stops17h 30m
Multiple Airlines
Sun 14/605:45
MAN
-
PTY
1 stop18h 55m
Multiple Airlines
Deal found 11/5£794
Sat 25/720:25
PTY
-
MAN
1 stop15h 50m
Multiple Airlines
Sun 23/805:45
MAN
-
PTY
2 stops34h 45m
Multiple Airlines
Deal found 12/5£816
Sat 25/720:25
PTY
-
MAN
1 stop15h 50m
Multiple Airlines
Mon 24/814:30
MAN
-
PTY
2 stops29h 45m
Multiple Airlines
Deal found 12/5£817
Tue 3/1110:00
PTY
-
MAN
2 stops42h 00m
United Airlines
Sat 7/1111:50
MAN
-
PTY
2 stops31h 55m
United Airlines
Deal found 12/5£818
Sat 25/720:25
PTY
-
MAN
1 stop15h 50m
Multiple Airlines
Tue 25/813:35
MAN
-
PTY
2 stops30h 40m
Multiple Airlines
Deal found 12/5£819
Sun 31/522:55
PTY
-
MAN
2 stops49h 35m
United Airlines
Sun 14/609:00
MAN
-
PTY
2 stops25h 04m
United Airlines
Deal found 8/5£823
Tue 28/722:55
PTY
-
MAN
2 stops49h 35m
United Airlines
Wed 26/809:00
MAN
-
PTY
2 stops49h 04m
United Airlines
Deal found 13/5£824
Sat 25/720:25
PTY
-
MAN
1 stop15h 50m
Multiple Airlines
Fri 28/816:50
MAN
-
PTY
2 stops27h 25m
Multiple Airlines
Deal found 12/5£825
Tue 23/619:54
DAV
-
MAN
2 stops43h 56m
Multiple Airlines
Tue 30/622:55
MAN
-
DAV
2 stops40h 08m
Multiple Airlines
Deal found 8/5£1,157
Thu 11/609:50
DAV
-
MAN
2 stops42h 20m
Multiple Airlines
Wed 17/620:50
MAN
-
DAV
2 stops40h 55m
Multiple Airlines
Deal found 13/5£1,222
Wed 10/609:50
DAV
-
MAN
2 stops41h 45m
Turkish Airlines
Sun 14/622:55
MAN
-
DAV
2 stops40h 08m
Turkish Airlines
Deal found 9/5£1,257

Find flight deals from Panama to Manchester

Keep the following information in mind while searching for Panama to Manchester flight deals. Data was last updated 13 May 2026.

Round-trip from

£749

One-way from

£537

Popular in

September

Cheapest in

July

Average price

£836
United Airlines
  • United Airlines
  • 18/9-21/9
  • 4 total stops
  • 58h 11m total
  • Panama to Manchester
United Airlines
  • United Airlines
  • 18/8
  • 2 total stops
  • 18h 40m total
  • Panama to Manchester
Highest demand for flights based on searches. 9% potential increase in price (£88 potential increase over avg. return price).
Cheapest flight prices on average. 7% potential price decrease (£58 potential savings vs. average return price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 May 2026.
Use the filters below to find and compare flights from Panama to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 18/9

09:45-06:30

2 stops38h 45m

Manchester

Mon 21/9

06:05-19:31

2 stops19h 26m

£749

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 3/11

10:00-09:00

2 stops42h 00m

Manchester

Sat 7/11

11:50-14:45

2 stops31h 55m

£818

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

22:55-06:30

2 stops49h 35m

Manchester

Sun 14/6

09:00-04:04

2 stops25h 04m

£823

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 21/7

22:55-06:30

2 stops49h 35m

Manchester

Wed 5/8

06:05-04:04

2 stops27h 59m

£838
Fastest return journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 20/7

22:55-06:30

2 stops25h 35m

Manchester

Wed 5/8

06:05-04:04

2 stops27h 59m

£838

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Tue 23/6

19:54-21:50

2 stops43h 56m

Manchester

Tue 30/6

22:55-09:03

2 stops40h 08m

£1,157

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Thu 11/6

09:50-10:10

2 stops42h 20m

Manchester

Wed 17/6

20:50-07:45

2 stops40h 55m

£1,222

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Wed 10/6

09:50-09:35

2 stops41h 45m

Manchester

Sun 14/6

22:55-09:03

2 stops40h 08m

£1,257

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Wed 24/6

19:54-20:05

2 stops42h 11m

Manchester

Wed 1/7

08:55-16:26

2 stops37h 31m

£1,408

DavidManchester

DAV - MAN

DAVMAN

David Enrique Malek

Wed 3/6

09:50-21:50

2 stops30h 00m

Manchester

Sun 7/6

13:10-09:03

2 stops49h 53m

£1,461

Flights are sorted by cheapest return flights first.

Deals found on 9/5

Showing 1-10 of 12 resultsSorted by cheapest first
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Best time to book a flight from Panama to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Manchester
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Manchester from Panama?

    Manchester (MAN) is the airport you will fly into if you book a flight from Panama to Manchester. It is only a 8.9 mi journey from Manchester (MAN) to Manchester’s city center.

  • How long is the flight from Panama to Manchester?

    United Airlines and Turkish Airlines can get you from Panama to Manchester in just under 38h 45m. Your travel time can differ by up to 3h. The distance between Panama and Manchester is about 5182 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Manchester.

  • Can I find deals for business class flights from Panama to Manchester?

    Yes. Cheapflights offers flight deals from Panama to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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