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Cheap flights from Panama to Manchester from £447

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
5 Dec — 12 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama to Manchester

Keep the following information in mind while searching for Panama to Manchester flight deals. Data was last updated 5 November 2025.

Round-trip from

£719

One-way from

£447

Popular in

September

Cheapest in

July

Average price

£865
Air France
  • Air France
  • 26/1-10/2
  • 2 total stops
  • 38h 05m total
  • Panama to Manchester
Search Deals
19/11
  • 19/11
  • 2 total stops
  • 31h 47m total
  • Panama to Manchester
Search Deals
Highest demand for flights based on searches. 17% potential increase in price (£169 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease (£69 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Panama to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama to Manchester
Explore the most affordable flight options available from Panama to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 November 2025.

Sun 28/1218:45PTY - MAN
1 stop16h 50mKLM
Thu 1/105:50MAN - PTY
1 stop15h 40mKLM
Deal found 3/11£783
Sun 28/1218:45PTY - MAN
1 stop34h 05mTurkish Airlines
Thu 1/114:05MAN - PTY
2 stops32h 00mTurkish Airlines
Deal found 3/11£1,076
Sun 28/1216:55PTY - MAN
2 stops20h 10mMultiple Airlines
Thu 1/118:20MAN - PTY
2 stops31h 00mMultiple Airlines
Deal found 3/11£1,302

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 5 November 2025.
Use the filters below to find and compare flights from Panama to Manchester that are best for you.

Fly from

Panama

Fly to

Manchester

Route

Depart

Return

Price

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 26/1

22:05-08:20

1 stop29h 15m

Manchester

Tue 10/2

06:00-20:10

1 stop19h 10m

£739

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 28/12

18:45-16:35

1 stop16h 50m

Manchester

Thu 1/1

05:50-16:30

1 stop15h 40m

£783

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 23/1

22:20-16:05

1 stop12h 45m

Manchester

Sun 8/2

17:25-19:55

1 stop31h 30m

£798

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 18/3

22:20-16:05

1 stop12h 45m

Manchester

Sun 22/3

06:00-20:10

1 stop19h 10m

£809

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 15/3

18:45-22:00

1 stop22h 15m

Manchester

Sat 21/3

11:00-16:30

1 stop34h 30m

£827

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 3/3

10:00-10:20

2 stops19h 20m

Manchester

Tue 10/3

09:25-13:45

2 stops33h 20m

£828

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 27/1

10:00-10:20

2 stops19h 20m

Manchester

Wed 11/2

06:00-17:07

2 stops40h 07m

£828

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 28/2

22:05-22:00

1 stop18h 55m

Manchester

Fri 24/4

08:55-16:50

1 stop13h 55m

£836

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 26/1

18:20-17:40

1 stop18h 20m

Manchester

Tue 10/2

18:20-20:30

2 stops31h 10m

£861

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 23/1

18:45-15:50

1 stop40h 05m

Manchester

Sun 8/2

22:25-17:05

2 stops23h 40m

£865

Flights are sorted by cheapest return flights first.

Deals found on 3/11

Showing 1-10 of 14 results
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Best time to book a flight from Panama to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Manchester

What is the cheapest time of day to fly from PA to MAN?

Find hourly flight availability from Panama to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 5 November 2025.

One of the essential ways to save on airfare from Panama to Manchester is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Panama to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from Panama?

    Manchester (MAN) is the airport you will fly into if you book a flight from Panama to Manchester. It is only a 8.9 mi journey from Manchester (MAN) to Manchester’s city center.

  • How long is the flight from Panama to Manchester?

    KLM, Air France, and Turkish Airlines can get you from Panama to Manchester in just under 12h 45m. Your travel time can differ by up to 17h 52m. The distance between Panama and Manchester is about 5182 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Manchester.

  • Can I find deals for business class flights from Panama to Manchester?

    Yes. Cheapflights offers flight deals from Panama to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

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Alternative routes for Panama to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
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Fly with Cheapflights

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How does Cheapflights help users find flights from Panama to Manchester?

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Can Cheapflights find flights from Panama to Manchester with no change fees?

Need flexible booking options for your flight to Manchester from Panama? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Not ready to book yet? You can track prices for flights from Panama to Manchester on Cheapflights with our Price Alert feature and get notified when better prices are available.

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