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Cheap flights from Panama City to Manchester from £354

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
17 Oct — 24 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Panama City to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 17 September 2025.

Round-trip from

£827

One-way from

£354

Popular in

September

Cheapest in

July

Average price

£1,621
KLM
  • KLM
  • 23/1-8/2
  • 2 total stops
  • 46h 15m total
  • Panama City to Manchester
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11/2
  • 11/2
  • 3 total stops
  • 45h 20m total
  • Panama City to Manchester
Search Deals
Highest demand for flights based on searches. 14% potential increase in price (£116 potential increase over avg. return price).
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Cheapest flight prices on average. 7% potential price decrease (£49 potential savings vs. average return price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Manchester

Cheapest flights from Panama City to Manchester
Explore the most affordable flight options available from Panama City to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2025.

Tue 23/910:25PTY - MAN
2 stops30h 15mMultiple Airlines
Fri 24/1019:55MAN - PTY
1 stop25h 45mMultiple Airlines
Deal found 15/9£823
Thu 18/911:05PTY - MAN
2 stops30h 15mMultiple Airlines
Fri 24/1019:55MAN - PTY
1 stop25h 45mMultiple Airlines
Deal found 15/9£853
Fri 19/909:45PTY - MAN
2 stops18h 40mUnited Airlines
Fri 24/1009:10MAN - PTY
2 stops41h 00mUnited Airlines
Deal found 15/9£876
Sat 20/915:30PTY - MAN
2 stops37h 00mUnited Airlines
Fri 24/1006:05MAN - PTY
2 stops38h 09mUnited Airlines
Deal found 15/9£889
Mon 22/911:05PTY - MAN
2 stops22h 25mMultiple Airlines
Fri 24/1019:55MAN - PTY
1 stop25h 45mMultiple Airlines
Deal found 15/9£909
Wed 17/909:13PTY - MAN
2 stops19h 07mUnited Airlines
Fri 24/1010:40MAN - PTY
2 stops32h 51mUnited Airlines
Deal found 15/9£931
Sat 25/1018:38PTY - MAN
2 stops34h 42mUnited Airlines
Sat 22/1106:10MAN - PTY
2 stops29h 03mUnited Airlines
Deal found 15/9£944
Thu 18/909:13PTY - MAN
2 stops19h 12mUnited Airlines
Fri 24/1010:40MAN - PTY
2 stops39h 54mUnited Airlines
Deal found 15/9£947
Sat 20/912:48PTY - MAN
2 stops22h 12mMultiple Airlines
Fri 24/1019:55MAN - PTY
1 stop25h 45mMultiple Airlines
Deal found 15/9£1,017
Sun 21/918:50PTY - MAN
1 stop31h 30mKLM
Fri 24/1017:30MAN - PTY
1 stop29h 20mKLM
Deal found 15/9£1,018
Fri 19/917:10PTY - MAN
1 stop19h 25mIberia
Fri 24/1019:15MAN - PTY
1 stop26h 25mIberia
Deal found 15/9£1,133
Sun 21/915:31PTY - MAN
2 stops48h 09mIberia
Fri 24/1019:15MAN - PTY
1 stop26h 25mIberia
Deal found 15/9£1,156

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 September 2025.
Use the filters below to find and compare flights from Panama City to Manchester that are best for you.

Fly from

Panama City

Fly to

Manchester

Route

Depart

Return

Price

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 23/1

18:45-15:50

1 stop40h 05m

Manchester

Sun 8/2

14:05-17:05

2 stops32h 00m

£833

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 23/1

10:00-10:20

2 stops19h 20m

Manchester

Sun 8/2

06:00-17:07

3 stops40h 07m

£906

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sat 25/10

22:29-10:20

2 stops30h 51m

Manchester

Sat 22/11

06:10-13:31

2 stops36h 21m

£944

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 11/2

09:45-12:05

3 stops45h 20m

£354

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 11/2

18:20-17:40

1 stop18h 20m

£505

Flights are sorted by cheapest return flights first.

Deals found on 16/9

Best time to book a flight from Panama City to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Manchester

What is the cheapest time of day to fly from PTY to MAN?

Find hourly flight availability from Panama City to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 September 2025.

When flying from Panama City to Manchester, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 22% versus a flight at midday.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Manchester?

    Turkish Airlines and United Airlines can get you from Panama City to Manchester in just under 19h 20m. Your travel time can differ by up to 20h 45m. There are 5182 mi between Panama City and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama City to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama City to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Manchester.

  • Can I find deals for business class flights from Panama City to Manchester?

    Yes. Cheapflights offers flight deals from Panama City to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Manchester (average of £117). Flying from Panama City to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Derby
Lincoln
Bradford
Harrogate
Preston
Stoke-on-Trent
Stockport
Wakefield
Southport
Bolton
Blackburn
Morecambe
Telford
Lancaster
Salford
Rochdale
Huddersfield
Wigan

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Alternative routes for Panama City to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Heathrow flights
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Panama City to Stansted flights
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Panama City to Birmingham flights
David to Manchester flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Panama City to Manchester?

When you search for this flight from Panama City to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Manchester?

Cheapflights helps you find that perfect flight to Manchester from Panama City by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama City to Manchester with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City to Manchester with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Manchester become cheaper?

Yes! Start tracking prices for Panama City to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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