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Cheap flights from Panama City to Manchester from £480

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
22 Apr — 29 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Manchester
Explore the most affordable flight options available from Panama City to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 March 2026.

Mon 27/420:25
PTY
-
MAN
2 stops21h 15m
Multiple Airlines
Thu 21/505:45
MAN
-
PTY
3 stops24h 50m
Multiple Airlines
Deal found 20/3£672
Tue 14/404:25
PTY
-
MAN
3 stops25h 15m
Multiple Airlines
Tue 5/513:35
MAN
-
PTY
2 stops30h 40m
Multiple Airlines
Deal found 20/3£730
Wed 8/422:20
PTY
-
MAN
1 stop18h 05m
Multiple Airlines
Wed 22/406:35
MAN
-
PTY
2 stops24h 00m
Multiple Airlines
Deal found 20/3£783
Wed 22/422:20
PTY
-
MAN
1 stop18h 05m
Multiple Airlines
Wed 13/506:35
MAN
-
PTY
2 stops37h 40m
Multiple Airlines
Deal found 22/3£792
Wed 15/422:20
PTY
-
MAN
1 stop18h 05m
Multiple Airlines
Wed 6/506:35
MAN
-
PTY
2 stops37h 40m
Multiple Airlines
Deal found 20/3£794
Fri 27/315:10
PTY
-
MAN
2 stops18h 40m
Multiple Airlines
Sun 5/407:00
MAN
-
PTY
2 stops19h 00m
Multiple Airlines
Deal found 21/3£803

Find flight deals from Panama City to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 23 March 2026.

Round-trip from

£672

One-way from

£480

Popular in

September

Cheapest in

July

Average price

£1,208
27/4-21/5
  • 27/4-21/5
  • 5 total stops
  • 46h 05m total
  • Panama City to Manchester
Search Deals
12/4
  • 12/4
  • 3 total stops
  • 59h 45m total
  • Panama City to Manchester
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£71 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease (£64 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 23 March 2026.
Use the filters below to find and compare flights from Panama City to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 22/4

22:20-22:25

1 stop18h 05m

Manchester

Wed 13/5

23:30-18:30

1 stop25h 00m

£812

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 18/9

15:30-06:30

3 stops33h 00m

Manchester

Mon 21/9

06:00-19:31

2 stops19h 31m

£816
Fastest return journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 22/4

04:25-09:45

3 stops23h 20m

Manchester

Wed 13/5

06:35-18:40

1 stop18h 05m

£832

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 15/4

04:25-08:30

3 stops22h 05m

Manchester

Wed 6/5

19:00-14:15

2 stops25h 15m

£869

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

15:30-06:30

2 stops57h 00m

Manchester

Sun 14/6

09:00-14:14

2 stops35h 14m

£875

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 31/5

21:30-08:50

1 stop29h 20m

Manchester

Sun 14/6

07:00-20:00

2 stops19h 00m

£893

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 28/4

20:05-22:25

1 stop20h 20m

Manchester

Tue 12/5

10:40-20:25

1 stop39h 45m

£895

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 22/4

09:45-10:25

2 stops18h 40m

Manchester

Sun 26/4

10:35-19:31

2 stops38h 56m

£903
Cheapest one-way

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 12/4

17:55-11:40

3 stops59h 45m

£480
Fastest single journey

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 8/4

22:20-22:25

1 stop18h 05m

£547

Flights are sorted by cheapest return flights first.

Deals found on 20/3

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama City to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Manchester?

    Turkish Airlines and United Airlines can get you from Panama City to Manchester in just under 18h 05m. Your travel time can differ by up to 14h 55m. There are 5182 mi between Panama City and Manchester. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama City to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama City to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Manchester.

  • Can I find deals for business class flights from Panama City to Manchester?

    Yes. Cheapflights offers flight deals from Panama City to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Stoke-on-Trent
Southport
Otley
Salford
Lancaster
Telford
Warrington
Huddersfield
Bolton
Preston
Wakefield
Macclesfield
Stockport
Wilmslow

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Heathrow flights
Panama City to Gatwick flights
Panama City to Stansted flights
Panama City to Edinburgh flights
Panama City to Birmingham flights
David to Manchester flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Manchester?

When you search for this flight from Panama City to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Manchester?

Cheapflights helps you find that perfect flight to Manchester from Panama City by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama City to Manchester with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City to Manchester with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Manchester become cheaper?

Yes! Start tracking prices for Panama City to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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