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Cheap flights from Panama City to Manchester from £746

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/5. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAN
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Manchester
Explore the most affordable flight options available from Panama City to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 January 2026.

Wed 13/503:20
PTY
-
MAN
3 stops26h 20m
Multiple Airlines
Tue 19/518:55
MAN
-
PTY
2 stops27h 35m
Multiple Airlines
Deal found 21/1£746
Wed 6/521:30
PTY
-
MAN
2 stops18h 15m
Multiple Airlines
Wed 13/509:30
MAN
-
PTY
1 stop16h 30m
Multiple Airlines
Deal found 20/1£749
Tue 5/520:25
PTY
-
MAN
1 stop22h 20m
Multiple Airlines
Wed 13/509:30
MAN
-
PTY
1 stop15h 10m
Multiple Airlines
Deal found 20/1£760
Fri 23/109:45
PTY
-
MAN
3 stops32h 35m
Multiple Airlines
Fri 30/119:50
MAN
-
PTY
2 stops29h 00m
Multiple Airlines
Deal found 19/1£787
Fri 18/915:20
PTY
-
MAN
3 stops33h 05m
United Airlines
Mon 21/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Deal found 20/1£791
Tue 24/221:30
PTY
-
MAN
1 stop15h 10m
Multiple Airlines
Wed 4/307:40
MAN
-
PTY
1 stop17h 05m
Multiple Airlines
Deal found 21/1£792
Mon 9/307:44
PTY
-
MAN
2 stops20h 46m
Multiple Airlines
Thu 12/310:10
MAN
-
PTY
2 stops25h 03m
Multiple Airlines
Deal found 20/1£807
Mon 9/321:45
PTY
-
MAN
1 stop31h 05m
Turkish Airlines
Thu 12/316:50
MAN
-
PTY
2 stops29h 15m
Turkish Airlines
Deal found 20/1£817
Mon 26/118:20
PTY
-
MAN
1 stop18h 20m
Iberia
Tue 10/218:20
MAN
-
PTY
1 stop27h 25m
Iberia
Deal found 21/1£828
Thu 26/209:34
PTY
-
MAN
2 stops27h 06m
Iberia
Tue 3/318:20
MAN
-
PTY
1 stop27h 25m
Iberia
Deal found 21/1£830

Find flight deals from Panama City to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 January 2026.

Round-trip from

£746

Popular in

September

Cheapest in

July

Average price

£1,793
13/5-19/5
  • 13/5-19/5
  • 5 total stops
  • 53h 55m total
  • Panama City to Manchester
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£91 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease (£59 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
Use the filters below to find and compare flights from Panama City to Manchester that are best for you.

Fly from

Panama City

Fly to

Manchester

Route

Depart

Return

Price

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Tue 24/2

21:30-17:40

1 stop15h 10m

Manchester

Wed 4/3

07:40-19:45

1 stop17h 05m

£792

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 9/3

07:44-09:30

2 stops20h 46m

Manchester

Thu 12/3

10:10-06:13

2 stops25h 03m

£807

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 26/2

09:34-17:40

2 stops27h 06m

Manchester

Tue 3/3

18:20-16:45

1 stop27h 25m

£830

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 25/2

21:30-21:15

1 stop18h 45m

Manchester

Wed 4/3

16:50-14:00

2 stops26h 10m

£831

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Wed 25/2

21:30-21:15

1 stop18h 45m

Manchester

Mon 2/3

15:45-01:00

2 stops38h 15m

£832

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Mon 9/3

18:20-17:40

1 stop18h 20m

Manchester

Thu 12/3

18:20-20:15

2 stops30h 55m

£839

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Sun 15/3

18:45-21:25

1 stop21h 40m

Manchester

Sat 21/3

22:25-17:05

2 stops23h 40m

£844

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Thu 26/2

21:30-15:00

2 stops36h 30m

Manchester

Tue 3/3

14:05-17:05

2 stops56h 00m

£846

Panama CityManchester

PTY - MAN

PTYMAN

Panama City Tocumen Intl

Fri 27/2

15:15-10:30

1 stop14h 15m

Manchester

Wed 4/3

20:40-16:30

1 stop24h 50m

£850

Flights are sorted by cheapest return flights first.

Deals found on 21/1

Best time to book a flight from Panama City to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Manchester

How much does it cost for a return flight from Panama City to Manchester?

Related info for your journey

Find useful and relevant information for your journey from Panama City to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Manchester?

    Iberia can get you from Panama City to Manchester in just under 27h 06m. Your travel time can differ by up to . There are 5182 mi between Panama City and Manchester.

  • Can I find deals for flights from Panama City to Manchester that include hotel bookings?

    Yes. In addition to deals on Panama City to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Manchester.

  • Can I find deals for business class flights from Panama City to Manchester?

    Yes. Cheapflights offers flight deals from Panama City to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Stoke-on-Trent
Otley
Telford
Southport
Lancaster
Wakefield
Bolton
Preston
Salford
Huddersfield
Stockport
Rochdale
Skipton
Crewe

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Heathrow flights
Panama City to Gatwick flights
Panama City to Stansted flights
Panama City to Edinburgh flights
Panama City to Birmingham flights
David to Manchester flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Manchester?

When you search for this flight from Panama City to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Manchester?

Cheapflights helps you find that perfect flight to Manchester from Panama City by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Panama City to Manchester with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City to Manchester with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Manchester become cheaper?

Yes! Start tracking prices for Panama City to Manchester flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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