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Cheap flights from Santa Ana to Manchester from £222

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — MAN
15 Mar — 22 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Ana to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from Santa Ana to Manchester
Explore the most affordable flight options available from Santa Ana to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 February 2026.

Tue 10/313:27
SNA
-
MAN
2 stops18h 23m
Lufthansa
Tue 17/309:25
MAN
-
SNA
2 stops18h 38m
Lufthansa
Deal found 10/2£457
Tue 10/310:55
SNA
-
MAN
2 stops17h 30m
American Airlines
Tue 17/309:40
MAN
-
SNA
2 stops18h 59m
American Airlines
Deal found 10/2£462
Tue 10/311:56
SNA
-
MAN
2 stops17h 49m
KLM
Tue 17/313:30
MAN
-
SNA
1 stop28h 54m
KLM
Deal found 10/2£464
Tue 21/413:23
SNA
-
MAN
2 stops17h 47m
British Airways
Wed 29/409:20
MAN
-
SNA
2 stops19h 53m
British Airways
Deal found 12/2£467
Tue 28/416:23
SNA
-
MAN
2 stops18h 37m
British Airways
Tue 5/508:35
MAN
-
SNA
2 stops20h 38m
British Airways
Deal found 10/2£474
Wed 5/816:30
SNA
-
MAN
2 stops18h 35m
British Airways
Wed 19/807:55
MAN
-
SNA
2 stops18h 10m
British Airways
Deal found 11/2£483
Tue 5/516:23
SNA
-
MAN
2 stops21h 12m
British Airways
Wed 27/519:50
MAN
-
SNA
2 stops30h 58m
British Airways
Deal found 11/2£507
Fri 3/416:32
SNA
-
MAN
2 stops22h 08m
British Airways
Mon 20/420:15
MAN
-
SNA
2 stops32h 58m
British Airways
Deal found 12/2£511
Sun 29/312:26
SNA
-
MAN
2 stops25h 04m
British Airways
Sun 5/410:35
MAN
-
SNA
2 stops19h 21m
British Airways
Deal found 12/2£519
Wed 15/407:45
SNA
-
MAN
2 stops18h 05m
British Airways
Wed 22/419:50
MAN
-
SNA
2 stops33h 00m
British Airways
Deal found 12/2£520
Tue 3/314:48
SNA
-
MAN
2 stops17h 42m
British Airways
Tue 10/308:55
MAN
-
SNA
2 stops20h 01m
British Airways
Deal found 10/2£525
Wed 4/314:48
SNA
-
MAN
2 stops17h 32m
British Airways
Tue 10/308:55
MAN
-
SNA
2 stops20h 01m
British Airways
Deal found 12/2£526

Find flight deals from Santa Ana to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 February 2026.

Round-trip from

£457

One-way from

£222

Popular in

June

Cheapest in

January

Average price

£552
Lufthansa
  • Lufthansa
  • 10/3-17/3
  • 4 total stops
  • 37h 01m total
  • Santa Ana to Manchester
Search Deals
Aer Lingus
  • Aer Lingus
  • 5/5
  • 2 total stops
  • 19h 10m total
  • Santa Ana to Manchester
Search Deals
Highest demand for flights based on searches. 15% potential increase in price (£78 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Santa Ana to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 February 2026.
Use the filters below to find and compare flights from Santa Ana to Manchester that are best for you.

Fly from

Santa Ana

Fly to

Manchester

Route

Depart

Return

Price

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Tue 10/3

13:27-14:50

2 stops18h 23m

Manchester

Tue 17/3

09:25-21:03

2 stops18h 38m

£457

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Tue 10/3

10:55-11:25

2 stops17h 30m

Manchester

Tue 17/3

09:40-21:39

2 stops18h 59m

£462

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Tue 10/3

11:56-12:45

2 stops17h 49m

Manchester

Tue 17/3

13:30-11:24

1 stop28h 54m

£464

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Tue 28/4

16:23-19:00

2 stops18h 37m

Manchester

Tue 5/5

08:35-21:13

2 stops20h 38m

£474

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Wed 5/8

16:30-19:05

2 stops18h 35m

Manchester

Wed 19/8

07:55-18:05

2 stops18h 10m

£483

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

16:23-21:35

2 stops21h 12m

Manchester

Wed 27/5

19:50-18:48

2 stops30h 58m

£507

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Fri 3/4

16:32-22:40

2 stops22h 08m

Manchester

Mon 20/4

20:15-21:13

2 stops32h 58m

£511

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Tue 3/3

14:48-16:30

2 stops17h 42m

Manchester

Tue 10/3

08:55-21:56

2 stops20h 01m

£525

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Wed 4/3

14:48-16:20

2 stops17h 32m

Manchester

Tue 10/3

08:55-21:56

2 stops20h 01m

£526

Santa AnaManchester

SNA - MAN

SNAMAN

Santa Ana J. Wayne/Orange Cnty

Thu 7/5

11:10-17:20

2 stops22h 10m

Manchester

Thu 14/5

06:05-22:30

2 stops24h 25m

£537

Flights are sorted by cheapest return flights first.

Deals found on 11/2

Showing 1-10 of 21 results
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Best time to book a flight from Santa Ana to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Santa Ana with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Manchester

What is the cheapest month to book a flight from Santa Ana to Manchester?

Currently, April is the cheapest month in which you can book a flight from Santa Ana to Manchester (average of £388). Flying from Santa Ana to Manchester in June is currently the most expensive (average of £582). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana to Manchester?

    Lufthansa, American Airlines, and KLM can get you from Santa Ana to Manchester in just under 17h 30m. Your travel time can differ by up to 53m. Santa Ana and Manchester are separated by a distance of 5295 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Santa Ana to Manchester that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Manchester.

  • Can I find deals for business class flights from Santa Ana to Manchester?

    Yes. Cheapflights offers flight deals from Santa Ana to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Manchester?

    Currently, April is the cheapest month in which you can book a flight from Santa Ana to Manchester (average of £388). Flying from Santa Ana to Manchester in June is currently the most expensive (average of £582). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
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Llandudno
Bradford
Lincoln
Derby
Harrogate
Stoke-on-Trent
Otley
Southport
Lancaster
Telford
Bolton
Preston
Wakefield
Salford
Huddersfield
Stockport
Warrington
Macclesfield
Rochdale

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Can Cheapflights find flights from Santa Ana to Manchester with no change fees?

Need flexible booking options for your flight to Manchester from Santa Ana? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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