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Cheap flights from Sheffield to Missouri from £323

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
8 Apr — 15 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Sheffield to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Sheffield to Missouri
Explore the most affordable flight options available from Sheffield to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 March 2026.

Fri 11/910:35
MAN
-
STL
1 stop14h 55m
British Airways
Mon 14/909:46
STL
-
MAN
2 stops21h 24m
British Airways
Deal found 4/3£655
Sun 19/420:45
MAN
-
STL
2 stops32h 28m
Virgin Atlantic
Sun 26/418:50
STL
-
MAN
1 stop32h 00m
Virgin Atlantic
Deal found 5/3£658
Thu 3/906:55
MAN
-
STL
2 stops14h 53m
British Airways
Wed 9/916:47
STL
-
MAN
2 stops16h 43m
British Airways
Deal found 5/3£659
Sun 19/420:00
MAN
-
STL
2 stops27h 21m
British Airways
Sun 26/412:27
STL
-
MAN
2 stops15h 28m
British Airways
Deal found 5/3£660
Mon 20/410:35
MAN
-
MCI
3 stops39h 10m
United Airlines
Mon 27/412:40
MCI
-
MAN
2 stops15h 10m
United Airlines
Deal found 6/3£890
Thu 12/1109:30
MAN
-
SGF
2 stops34h 10m
United Airlines
Mon 16/1115:03
SGF
-
MAN
2 stops13h 17m
United Airlines
Deal found 4/3£894
Wed 22/410:35
MAN
-
MCI
2 stops28h 17m
United Airlines
Wed 29/412:40
MCI
-
MAN
2 stops15h 10m
United Airlines
Deal found 8/3£895
Thu 24/905:55
MAN
-
COU
2 stops24h 38m
United Airlines
Mon 28/905:00
COU
-
MAN
2 stops22h 50m
United Airlines
Deal found 4/3£901
Thu 17/911:05
MAN
-
MCI
2 stops33h 59m
United Airlines
Mon 21/907:45
MCI
-
MAN
2 stops27h 25m
United Airlines
Deal found 4/3£902
Thu 19/1106:10
MAN
-
COU
2 stops21h 10m
United Airlines
Mon 23/1105:00
COU
-
MAN
2 stops30h 00m
United Airlines
Deal found 5/3£923
Fri 2/1005:55
MAN
-
MCI
2 stops40h 08m
United Airlines
Tue 6/1008:05
MCI
-
MAN
2 stops19h 45m
United Airlines
Deal found 8/3£934
Fri 3/411:10
MAN
-
MCI
2 stops31h 14m
Lufthansa
Sat 25/412:40
MCI
-
MAN
2 stops15h 10m
Lufthansa
Deal found 5/3£939

Find flight deals from Sheffield to Missouri

Keep the following information in mind while searching for Sheffield to Missouri flight deals. Data was last updated 9 March 2026.

Round-trip from

£658

One-way from

£323

Popular in

August

Cheapest in

December

Average price

£781
Virgin Atlantic
  • Virgin Atlantic
  • 19/4-26/4
  • 3 total stops
  • 64h 28m total
  • Sheffield to Missouri
Search Deals
1/6
  • 1/6
  • 3 total stops
  • 56h 28m total
  • Sheffield to Missouri
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£88 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Sheffield to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 March 2026.
Use the filters below to find and compare flights from Sheffield to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Sun 19/4

20:45-23:13

2 stops32h 28m

Lambert-St Louis

Sun 26/4

18:50-08:50

1 stop32h 00m

£658
Fastest return journey

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 3/9

06:55-20:19

2 stops19h 24m

Lambert-St Louis

Wed 9/9

21:35-15:30

1 stop11h 55m

£659

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Sun 19/4

20:00-17:21

2 stops27h 21m

Lambert-St Louis

Sun 26/4

12:27-09:55

2 stops15h 28m

£660

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 6/5

10:55-08:24

2 stops27h 29m

Lambert-St Louis

Sun 10/5

20:03-22:35

2 stops20h 32m

£700

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Mon 20/4

10:35-19:45

3 stops39h 10m

Kansas City

Mon 27/4

12:40-09:50

2 stops15h 10m

£890

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Wed 22/4

10:35-08:52

2 stops28h 17m

Kansas City

Wed 29/4

12:40-09:50

2 stops15h 10m

£895

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Sat 18/4

09:35-23:50

2 stops20h 15m

Kansas City

Sat 25/4

09:36-11:45

2 stops20h 09m

£912

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 3/4

11:10-12:24

2 stops31h 14m

Kansas City

Sat 25/4

12:40-09:50

2 stops15h 10m

£939

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 31/7

13:00-09:40

1 stop26h 40m

Lambert-St Louis

Tue 15/12

09:00-06:40

2 stops15h 40m

£958

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Sat 1/8

13:15-23:38

1 stop16h 23m

Lambert-St Louis

Wed 16/12

13:30-10:30

1 stop15h 00m

£958

Flights are sorted by cheapest return flights first.

Deals found on 6/3

Showing 1-10 of 31 resultsSorted by cheapest first
1
2
3
4

Best time to book a flight from Sheffield to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Sheffield with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sheffield to Missouri

What is the cheapest month to book a flight from Sheffield to Missouri?

Currently, May is the cheapest month in which you can book a flight from Sheffield to Missouri (average of £260). Flying from Sheffield to Missouri in August is currently the most expensive (average of £777). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Sheffield to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 9 March 2026.
Read reviews from past customers who have flown with KLM,Virgin Atlantic, andUnited Airlines from Sheffield to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,468 reviews
Check prices

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,468 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
680 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,409 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Aer Lingus
7.2
Good
1,473 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6.7
Okay
7,781 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Boarding

7.8

Comfort

7.6

Food

7.3

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Sheffield to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sheffield to Missouri?

    For as low as £659, Virgin Atlantic can have you in Missouri from Sheffield in 19h 24m. The distance between Sheffield and Missouri is about 4061 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Sheffield to Missouri?

    While some choose either Manchester - Lambert-St Louis or Manchester - Columbia Regional, Manchester - Kansas City is the most popular route from Sheffield to Missouri.

  • Can I find deals for flights from Sheffield to Missouri that include hotel bookings?

    Yes. In addition to deals on Sheffield to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Sheffield to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sheffield to Missouri.

  • Can I find deals for business class flights from Sheffield to Missouri?

    Yes. Cheapflights offers flight deals from Sheffield to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sheffield to Missouri?

    Currently, May is the cheapest month in which you can book a flight from Sheffield to Missouri (average of £260). Flying from Sheffield to Missouri in August is currently the most expensive (average of £777). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Sheffield to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Sheffield to Missouri

Discover the top 9 airlines that operate flights from Sheffield to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 March 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£554Average£822FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapest£566Average£938FlexibilityNo cancel feeOn-time75%
Search KLM flights
Scandinavian AirlinesCheapest£582Average£711FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
DeltaCheapest£608Average£859FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Virgin AtlanticCheapest£657Average£943FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
United AirlinesCheapest£678Average£834FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£722Average£898FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
American AirlinesCheapest£840Average£1,039FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
Aer LingusCheapest£844Average£1,021FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Sheffield to Missouri?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Sheffield to Missouri. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Sheffield to Missouri?

Cheapflights simply makes it quick and affordable to book flights from Sheffield to Missouri by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Sheffield to Missouri with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Sheffield to Missouri flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Sheffield to Missouri become cheaper?

Yes, Cheapflights offers price alerts on Sheffield to Missouri flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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