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Cheap flights from London Heathrow Airport to Panama City, Florida from £425

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/6. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — ECP
20 Mar — 27 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Panama City
Explore the most affordable flight options available from Heathrow to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 February 2026.

Wed 2/907:25
LHR
-
ECP
2 stops18h 41m
United Airlines
Wed 7/1016:55
ECP
-
LHR
1 stop12h 40m
United Airlines
Deal found 14/2£491
Tue 17/308:55
LHR
-
ECP
1 stop14h 03m
Virgin Atlantic
Thu 26/316:23
ECP
-
LHR
1 stop11h 37m
Virgin Atlantic
Deal found 17/2£494
Tue 17/308:00
LHR
-
ECP
2 stops18h 57m
United Airlines
Thu 26/317:03
ECP
-
LHR
1 stop12h 12m
United Airlines
Deal found 17/2£497
Fri 30/1009:00
LHR
-
ECP
2 stops29h 37m
United Airlines
Tue 3/1111:10
ECP
-
LHR
1 stop14h 20m
United Airlines
Deal found 17/2£510
Wed 18/310:45
LHR
-
ECP
1 stop14h 02m
Virgin Atlantic
Sat 28/313:30
ECP
-
LHR
1 stop11h 55m
Virgin Atlantic
Deal found 17/2£516
Wed 18/309:10
LHR
-
ECP
2 stops17h 47m
United Airlines
Sat 28/317:03
ECP
-
LHR
2 stops31h 42m
United Airlines
Deal found 17/2£527
Thu 19/310:45
LHR
-
ECP
1 stop12h 13m
Virgin Atlantic
Sun 29/318:43
ECP
-
LHR
2 stops28h 37m
Virgin Atlantic
Deal found 17/2£528

Find flight deals from Heathrow to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Heathrow (LHR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 February 2026.

Round-trip from

£494

One-way from

£425

Popular in

December

Cheapest in

September

Average price

£691
Virgin Atlantic
  • Virgin Atlantic
  • 17/3-26/3
  • 2 total stops
  • 25h 40m total
  • London to Panama City
Search Deals
Brussels Airlines
  • Brussels Airlines
  • 15/6
  • 1 total stop
  • 17h 58m total
  • London to Panama City
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£17 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£20 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 February 2026.
Use the filters below to find and compare flights from London Heathrow Airport to Panama City that are best for you.

Fly from

Heathrow

Fly to

Panama City

Route

Depart

Return

Price

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Tue 17/3

11:30-23:04

2 stops16h 34m

Panama City NW Florida Beaches

Thu 26/3

16:23-11:25

2 stops14h 02m

£506

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Wed 18/3

07:40-09:43

1 stop31h 03m

Panama City NW Florida Beaches

Sat 28/3

17:03-05:45

2 stops31h 42m

£527

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 19/3

10:45-17:58

1 stop12h 13m

Panama City NW Florida Beaches

Sun 29/3

18:43-05:20

2 stops28h 37m

£528

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 12/3

15:50-23:04

1 stop12h 14m

Panama City NW Florida Beaches

Sun 22/3

18:43-06:25

1 stop30h 42m

£530

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 12/3

13:30-09:43

2 stops25h 13m

Panama City NW Florida Beaches

Sun 22/3

14:10-05:55

1 stop34h 45m

£538

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sat 25/4

09:20-15:26

1 stop12h 06m

Panama City NW Florida Beaches

Mon 4/5

08:21-06:25

1 stop16h 04m

£558

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 8/6

08:00-20:01

2 stops42h 01m

Panama City NW Florida Beaches

Mon 15/6

06:30-10:40

2 stops22h 10m

£578

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 19/3

11:45-08:40

2 stops25h 55m

Panama City NW Florida Beaches

Sun 29/3

18:43-10:30

2 stops33h 47m

£592

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 15/6

10:00-21:58

1 stop17h 58m

£425

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 15/6

10:40-19:36

2 stops14h 56m

£441

Flights are sorted by cheapest return flights first.

Deals found on 15/2

Showing 1-10 of 12 results
1
2

Best time to book a flight from Heathrow to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Panama City

How far ahead should I book a flight from London Heathrow Airport to Panama City, Florida?

Use this chart to determine the optimal time to book a return flight from Heathrow to Panama City. Price data was last updated on 13 February 2026.

Booking 34 days in advance of your planned departure date is, on average, the best time to get cheap flights from London Heathrow Airport to Panama City, Florida. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £327). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 18 February 2026.
Read reviews from past customers who have flown with KLM, Virgin Atlantic, andUnited Airlines from London Heathrow Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,456 reviews
Check prices

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.7
Good
1,456 reviews
KLM
7.7
Good
1,456 reviews
Check prices

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
678 reviews
KLM
7.7
Good
1,456 reviews
Check prices

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,311 reviews
KLM
7.7
Good
1,456 reviews
Check prices

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Overall

7.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Heathrow to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from London Heathrow?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from London Heathrow. On average, NW Florida Beaches has 0 inbound flights from London Heathrow per day from 3 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from London Heathrow Airport to Panama City, Florida?

    United Airlines, Virgin Atlantic, and Delta can get you from London Heathrow Airport to Panama City, Florida in just under 12h 06m. Your travel time can differ by up to 18h 57m. The distance from London Heathrow Airport to Panama City, Florida is about 4416 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines flying from London Heathrow Airport to Panama City, Florida round-trip?

    United Airlines, at £343, was found to be the cheapest airline from London Heathrow Airport to Panama City, Florida.Alternate airlines flying return to your destination include Virgin Atlantic and KLM. United Airlines is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Heathrow to Panama City that include hotel bookings?

    Yes. In addition to deals on Heathrow to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Panama City.

  • Can I find deals for business class flights from Heathrow to Panama City?

    Yes. Cheapflights offers flight deals from Heathrow to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

    Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £327). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Heathrow to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Heathrow to Panama City

Discover the top 3 airlines that operate flights from Heathrow to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 February 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£343Average£652FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Virgin AtlanticCheapest£458Average£567FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£480Average£884FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Heathrow to Panama City?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Heathrow to Panama City. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Heathrow.

Can Cheapflights find flights from Heathrow to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Heathrow to Panama City with no change fees.

Can Cheapflights notify me if prices for flights from Heathrow to Panama City become cheaper?

Of course! You can now track prices for flights from Heathrow to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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