Cheap flights from London Heathrow Airport to Panama City, Florida from £331

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/4. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — ECP
24 Feb — 3 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Panama City
Explore the most affordable flight options available from Heathrow to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 January 2026.

Fri 30/1006:35
LHR
-
ECP
2 stops35h 02m
United Airlines
Tue 3/1111:10
ECP
-
LHR
1 stop17h 05m
United Airlines
Deal found 23/1£392
Wed 4/307:40
LHR
-
ECP
2 stops18h 11m
United Airlines
Wed 11/314:10
ECP
-
LHR
2 stops15h 55m
United Airlines
Deal found 25/1£407
Sat 31/1010:00
LHR
-
ECP
1 stop15h 06m
United Airlines
Sat 14/1111:10
ECP
-
LHR
1 stop17h 05m
United Airlines
Deal found 25/1£419
Fri 23/1016:40
LHR
-
ECP
2 stops27h 37m
United Airlines
Mon 2/1116:55
ECP
-
LHR
1 stop32h 35m
United Airlines
Deal found 24/1£425
Wed 25/312:05
LHR
-
ECP
1 stop14h 52m
United Airlines
Mon 13/416:57
ECP
-
LHR
1 stop32h 43m
United Airlines
Deal found 25/1£426
Fri 23/1010:00
LHR
-
ECP
1 stop16h 06m
United Airlines
Sat 7/1106:40
ECP
-
LHR
1 stop18h 50m
United Airlines
Deal found 25/1£429
Sat 24/1016:40
LHR
-
ECP
2 stops25h 57m
United Airlines
Sat 7/1111:10
ECP
-
LHR
2 stops19h 50m
United Airlines
Deal found 25/1£431
Thu 22/1010:00
LHR
-
ECP
1 stop16h 06m
United Airlines
Mon 2/1111:10
ECP
-
LHR
1 stop17h 05m
United Airlines
Deal found 24/1£435
Sat 31/1010:00
LHR
-
ECP
1 stop15h 06m
United Airlines
Sun 15/1111:10
ECP
-
LHR
1 stop14h 20m
United Airlines
Deal found 25/1£437
Fri 23/1013:40
LHR
-
ECP
1 stop30h 37m
United Airlines
Sat 31/1016:55
ECP
-
LHR
1 stop33h 35m
United Airlines
Deal found 25/1£438

Find flight deals from Heathrow to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Heathrow (LHR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 25 January 2026.

Round-trip from

£432

One-way from

£360

Popular in

December

Cheapest in

September

Average price

£498
United Airlines
  • United Airlines
  • 7/4-16/4
  • 3 total stops
  • 32h 34m total
  • London to Panama City
United Airlines
  • United Airlines
  • 13/3
  • 2 total stops
  • 31h 53m total
  • London to Panama City
Highest demand for flights based on searches. 3% potential increase in price (£15 potential increase over avg. return price).
Cheapest flight prices on average. 4% potential price decrease (£20 potential savings vs. average return price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 25 January 2026.
Use the filters below to find and compare flights from London Heathrow Airport to Panama City that are best for you.

Fly from

Heathrow

Fly to

Panama City

Route

Depart

Return

Price

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 8/6

10:00-14:17

1 stop34h 17m

Panama City NW Florida Beaches

Mon 15/6

11:10-06:30

2 stops37h 20m

£454

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sun 29/3

13:40-21:59

1 stop14h 19m

Panama City NW Florida Beaches

Mon 13/4

16:57-06:45

2 stops31h 48m

£588

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Wed 25/3

10:00-21:57

1 stop16h 57m

Panama City NW Florida Beaches

Sun 12/4

06:30-07:40

1 stop19h 10m

£588

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Wed 25/3

08:00-21:57

2 stops18h 57m

Panama City NW Florida Beaches

Fri 10/4

10:10-07:40

1 stop15h 30m

£588

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 26/3

12:05-21:57

1 stop14h 52m

Panama City NW Florida Beaches

Mon 13/4

16:57-06:45

2 stops31h 48m

£588

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 4/6

07:30-21:59

2 stops20h 29m

Panama City NW Florida Beaches

Sat 13/6

14:15-06:55

2 stops34h 40m

£606

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 8/6

12:55-09:31

1 stop26h 36m

Panama City NW Florida Beaches

Mon 15/6

15:20-10:55

1 stop13h 35m

£623

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Wed 15/4

07:25-21:59

2 stops20h 34m

£331

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Fri 13/3

06:50-09:43

2 stops31h 53m

£360

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sat 14/3

13:35-09:43

1 stop25h 08m

£387

Flights are sorted by cheapest return flights first.

Deals found on 25/1

Showing 1-10 of 15 results
1
2

Best time to book a flight from Heathrow to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Panama City

How far ahead should I book a flight from London Heathrow Airport to Panama City, Florida?

Use this chart to determine the optimal time to book a return flight from Heathrow to Panama City. Price data was last updated on 23 January 2026.

Booking 34 days in advance of your planned departure date is, on average, the best time to get cheap flights from London Heathrow Airport to Panama City, Florida. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £327). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 25 January 2026.
Read reviews from past customers who have flown with KLM, Virgin Atlantic, andUnited Airlines from London Heathrow Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.1

Overall

7.7

Comfort

7.6

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.1

Overall

7.7

Comfort

7.6

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.1

Overall

7.7

Comfort

7.6

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.1

Overall

7.7

Comfort

7.6

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Heathrow to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from London Heathrow?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from London Heathrow. On average, NW Florida Beaches has 0 inbound flights from London Heathrow per day from 3 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from London Heathrow Airport to Panama City, Florida?

    United Airlines can get you from London Heathrow Airport to Panama City, Florida in just under 34h 17m. Your travel time can differ by up to . The distance from London Heathrow Airport to Panama City, Florida is about 4416 mi.

  • What are the cheapest airlines flying from London Heathrow Airport to Panama City, Florida round-trip?

    United Airlines, at £342, was found to be the cheapest airline from London Heathrow Airport to Panama City, Florida.Alternate airlines flying return to your destination include Virgin Atlantic and KLM. United Airlines is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Heathrow to Panama City that include hotel bookings?

    Yes. In addition to deals on Heathrow to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Panama City.

  • Can I find deals for business class flights from Heathrow to Panama City?

    Yes. Cheapflights offers flight deals from Heathrow to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

    Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £327). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Heathrow to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Heathrow to Panama City

Discover the top 3 airlines that operate flights from Heathrow to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 25 January 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£342Average£678FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Virgin AtlanticCheapest£454Average£562FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£462Average£879FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Heathrow to Panama City?

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Why should you use Cheapflights to find cheap flight tickets from Heathrow to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Heathrow.

Can Cheapflights find flights from Heathrow to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Heathrow to Panama City with no change fees.

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