Cheap flights from London Heathrow Airport to Panama City, Florida from £572

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/4. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — ECP
27 Apr — 4 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Panama City
Explore the most affordable flight options available from Heathrow to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 March 2026.

Tue 28/411:15
LHR
-
ECP
1 stop12h 45m
Virgin Atlantic
Sun 3/518:46
ECP
-
LHR
1 stop29h 39m
Virgin Atlantic
Deal found 25/3£572
Mon 27/407:25
LHR
-
ECP
2 stops20h 34m
United Airlines
Mon 4/510:30
ECP
-
LHR
1 stop14h 15m
United Airlines
Deal found 27/3£576
Tue 28/411:05
LHR
-
ECP
2 stops16h 54m
United Airlines
Sun 3/516:55
ECP
-
LHR
2 stops32h 00m
United Airlines
Deal found 25/3£583
Mon 20/409:30
LHR
-
ECP
2 stops18h 29m
United Airlines
Fri 1/516:55
ECP
-
LHR
1 stop12h 40m
United Airlines
Deal found 23/3£587
Thu 3/1206:35
LHR
-
ECP
2 stops19h 31m
United Airlines
Mon 7/1210:25
ECP
-
LHR
1 stop18h 50m
United Airlines
Deal found 25/3£588
Mon 20/412:55
LHR
-
ECP
1 stop15h 03m
Multiple Airlines
Fri 1/513:54
ECP
-
LHR
1 stop14h 56m
Multiple Airlines
Deal found 23/3£598
Sun 4/1013:25
LHR
-
ECP
1 stop12h 12m
Virgin Atlantic
Sun 18/1019:05
ECP
-
LHR
1 stop29h 20m
Virgin Atlantic
Deal found 26/3£600
Mon 11/508:40
LHR
-
ECP
2 stops16h 29m
Delta
Mon 18/507:41
ECP
-
LHR
1 stop17h 34m
Delta
Deal found 27/3£604

Find flight deals from Heathrow to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Heathrow (LHR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 March 2026.

Round-trip from

£572

Popular in

December

Cheapest in

September

Average price

£600
Virgin Atlantic
  • Virgin Atlantic
  • 28/4-3/5
  • 2 total stops
  • 42h 24m total
  • London to Panama City
Highest demand for flights based on searches. 4% potential increase in price (£22 potential increase over avg. return price).
Cheapest flight prices on average. 4% potential price decrease (£22 potential savings vs. average return price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2026.
Use the filters below to find and compare flights from London Heathrow Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 20/4

09:30-21:59

2 stops18h 29m

Panama City NW Florida Beaches

Fri 1/5

10:30-11:35

2 stops19h 05m

£587
Fastest return journey

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 20/4

12:55-21:58

1 stop15h 03m

Panama City NW Florida Beaches

Fri 1/5

13:54-10:50

1 stop14h 56m

£598

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 27/4

10:00-21:59

1 stop17h 59m

Panama City NW Florida Beaches

Mon 4/5

10:30-08:30

1 stop16h 00m

£601

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 20/4

11:45-23:12

2 stops17h 27m

Panama City NW Florida Beaches

Fri 1/5

18:46-08:50

2 stops32h 04m

£616

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 8/6

07:25-09:44

2 stops32h 19m

Panama City NW Florida Beaches

Mon 15/6

06:30-08:20

2 stops19h 50m

£662

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sun 12/4

09:30-09:35

2 stops30h 05m

Panama City NW Florida Beaches

Fri 8/5

06:30-11:35

1 stop23h 05m

£686
Cheapest one-way

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Tue 28/7

06:30-16:22

2 stops15h 52m

£592

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Tue 28/7

08:00-13:21

1 stop35h 21m

£595
Fastest single journey

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 16/7

13:40-21:58

1 stop14h 18m

£637

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 16/7

07:05-23:37

3 stops22h 32m

£2,298

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Heathrow to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Panama City

What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £335). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £495). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from London Heathrow Airport to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 28 March 2026.
Read reviews from past customers who have flown with KLM,Virgin Atlantic, andUnited Airlines from London Heathrow Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.8

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Overall

7.8

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Overall

7.8

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Overall

7.8

Entertainment

7.1

Comfort

7.6

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Heathrow to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from London Heathrow?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from London Heathrow. On average, NW Florida Beaches has 0 inbound flights from London Heathrow per day from 3 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from London Heathrow Airport to Panama City, Florida?

    United Airlines and Virgin Atlantic can get you from London Heathrow Airport to Panama City, Florida in just under 17h 27m. Your travel time can differ by up to 1h 02m. The distance from London Heathrow Airport to Panama City, Florida is about 4416 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines flying from London Heathrow Airport to Panama City, Florida round-trip?

    United Airlines, at £350, was found to be the cheapest airline from London Heathrow Airport to Panama City, Florida.Alternate airlines flying return to your destination include Virgin Atlantic and KLM. United Airlines is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Heathrow to Panama City that include hotel bookings?

    Yes. In addition to deals on Heathrow to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Panama City.

  • Can I find deals for business class flights from Heathrow to Panama City?

    Yes. Cheapflights offers flight deals from Heathrow to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

    Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £335). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £495). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Heathrow to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Heathrow to Panama City

Discover the top 3 airlines that operate flights from Heathrow to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£350Average£604FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Virgin AtlanticCheapest£470Average£573FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£490Average£902FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Heathrow to Panama City?

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Why should you use Cheapflights to find cheap flight tickets from Heathrow to Panama City?

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Can Cheapflights find flights from Heathrow to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Heathrow to Panama City with no change fees.

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