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Cheap flights from Frankfurt am Main Airport to Panama City from £341

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/5. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
5 May — 12 May1
1 adult

Cheap flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 April 2025.

Round-trip from

£470

One-way from

£341

Popular in

December

Cheapest in

May

Average price

£530
United Airlines
  • United Airlines
  • 25/8-7/9
  • 4 total stops
  • 45h 35m total
  • Frankfurt am Main to Panama City
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Air Europa
  • Air Europa
  • 31/5
  • 1 total stop
  • 14h 45m total
  • Frankfurt am Main to Panama City
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£48 potential increase over avg. return price).
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Cheapest flight prices on average. 4% potential price decrease (£18 potential savings vs. average return price).
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Average for round-trip flights in April 2025
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Find flight deals from Frankfurt to Panama City

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.

Mon 25/817:35FRA - PTY
2 stops27h 15mUnited Airlines
Sun 7/909:45PTY - FRA
2 stops18h 20mUnited Airlines
Deal found 29/4£470
Mon 9/619:10FRA - PTY
1 stop30h 30mAir Europa
Sun 22/620:25PTY - FRA
1 stop14h 25mAir Europa
Deal found 29/4£481
Sun 22/607:05FRA - PTY
1 stop17h 40mMultiple Airlines
Mon 7/718:50PTY - FRA
1 stop33h 10mMultiple Airlines
Deal found 29/4£482
Sat 16/811:50FRA - PTY
2 stops32h 04mDelta
Tue 2/914:12PTY - FRA
2 stops35h 28mDelta
Deal found 29/4£641
Sun 28/1218:20FRA - PTY
1 stop31h 40mTurkish Airlines
Mon 9/318:55PTY - FRA
1 stop21h 20mTurkish Airlines
Deal found 29/4£650
Wed 16/721:50FRA - PTY
Nonstop11h 50mCondor
Thu 7/811:05PTY - FRA
Nonstop11h 10mCondor
Deal found 30/4£807

Cheapflights Fare Finder

Customise your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 April 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Frankfurt

Fly to

Panama City

Route

Depart

Return

Price

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Mon 25/8

17:35-13:50

2 stops27h 15m

Panama City Tocumen Intl

Sat 6/9

09:45-11:05

2 stops18h 20m

£470

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Mon 9/6

19:10-18:40

1 stop30h 30m

Panama City Tocumen Intl

Sun 22/6

20:25-17:50

1 stop14h 25m

£481

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sun 22/6

07:05-17:45

1 stop17h 40m

Panama City Tocumen Intl

Mon 7/7

18:50-11:00

1 stop33h 10m

£482

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 16/8

11:50-12:54

2 stops32h 04m

Panama City Tocumen Intl

Tue 2/9

14:12-08:40

2 stops35h 28m

£641

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 15/8

22:00-18:20

2 stops27h 20m

Panama City Tocumen Intl

Tue 2/9

20:00-13:25

1 stop34h 25m

£656

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 16/7

21:50-02:40

Nonstop11h 50m

Panama City Tocumen Intl

Thu 7/8

11:05-05:15

Nonstop11h 10m

£807

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sun 6/7

07:00-17:45

2 stops17h 45m

Panama City Tocumen Intl

Mon 28/7

19:55-17:45

2 stops14h 50m

£1,050

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Mon 9/6

20:00-08:55

2 stops19h 55m

Panama City Tocumen Intl

Tue 17/6

03:20-08:35

2 stops22h 15m

£1,179

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 31/5

10:55-18:40

1 stop14h 45m

£341

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 31/5

07:00-17:45

2 stops17h 45m

£515

Flights are sorted by cheapest return flights first.

Deals found on 29/4

Showing 1-10 of 11 results
1
2

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Frankfurt to Panama City. Price data was last updated on 25 April 2025.

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to Panama City, you should look to book at least 54 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, April is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £763). Flying from Frankfurt am Main Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 30 April 2025.
Delta
8.0
Very Good
7,936 reviews
Check prices

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
Delta
8.0
Very Good
7,936 reviews
Delta
8.0
Very Good
7,936 reviews
Check prices

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very Good
7,936 reviews
Check prices

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very Good
7,936 reviews
Check prices

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
Turkish Airlines
7.3
Good
3,790 reviews
Delta
8.0
Very Good
7,936 reviews
Check prices

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
Air Europa
6.9
Okay
510 reviews
Delta
8.0
Very Good
7,936 reviews
Check prices

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City Tocumen Intl from Frankfurt am Main on a regular basis.

  • What are the cheapest airlines flying from Frankfurt am Main Airport to Panama City round-trip?

    Our cheapest airline available from Frankfurt am Main Airport to Panama City is United Airlines. Our recent data shows that you can find tickets from as low as £470 on this airline. Additional options worth looking into are Air Europa and Delta, starting at £481 and £641 round-trip. United Airlines is 13% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Frankfurt am Main Airport to Panama City one-way?

    To fly one-way, consider booking your trip with Air Europa, which is currently one of the cheapest options available, starting at £341. KLM flights start at £515 while deals on Turkish Airlines start at £782 one-way.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £763). Flying from Frankfurt am Main Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Frankfurt am Main Airport?

Book flights to Frankfurt am Main Airport if you plan to visit one of these locations
San Blas

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