Cheap flights from Panama City to Frankfurt am Main Airport from £503

PTY — FRA
3 Dec — 10 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Panama City to Frankfurt

Enter your travel dates to find the best prices.

Cheapest flights from Panama City to Frankfurt

Tue 1/1221:30 -
1 stop14h 25m
Thu 21/110:45 -
1 stop15h 00m
Deal found 30/10£726
Tue 1/1221:30 -
1 stop14h 25m
Wed 20/118:55 -
1 stop30h 50m
Deal found 30/10£735
Mon 30/1118:45 -
1 stop17h 15m
Tue 19/106:50 -
1 stop19h 05m
Deal found 30/10£757
Tue 1/1221:30 -
1 stop14h 25m
Sun 17/118:55 -
1 stop30h 50m
Deal found 30/10£758
Thu 5/1118:45 -
1 stop12h 50m
Tue 2/210:15 -
2 stops26h 08m
Deal found 1/11£761
Mon 16/1118:45 -
1 stop12h 50m
Mon 30/1107:05 -
2 stops19h 15m
Deal found 2/11£763
Fri 27/1122:00 -
1 stop18h 10m
Wed 20/106:50 -
1 stop19h 15m
Deal found 30/10£772
Fri 25/1221:55 -
1 stop18h 30m
Mon 18/110:20 -
2 stops16h 00m
Deal found 30/10£779
Tue 1/1221:30 -
1 stop14h 25m
Sat 16/118:55 -
1 stop30h 50m
Deal found 30/10£782
Fri 27/1110:00 -
2 stops20h 00m
Sun 17/113:50 -
1 stop30h 55m
Deal found 30/10£783
Wed 2/1208:55 -
2 stops22h 50m
Wed 9/1213:30 -
2 stops31h 15m
Deal found 2/11£784
Thu 3/1210:00 -
1 stop15h 20m
Wed 20/113:50 -
1 stop30h 55m
Deal found 30/10£785

Find flight deals from Panama City to Frankfurt

Round-trip from

£726

One-way from

£503

Popular in

January

Cheapest in

November

Average price

£621
Air Europa
  • Air Europa
  • 1/12-21/1
  • 2 total stops
  • 29h 25m total
  • Panama City to Frankfurt am Main
11/12-31/12
  • 11/12-31/12
  • 3 total stops
  • 32h 10m total
  • Panama City to Frankfurt am Main
Highest demand for flights based on searches. 9% potential increase in price (£57 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Frankfurt am Main Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Thu 18/3

18:45-18:00

1 stop17h 15m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£565
Fastest return journey

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Fri 12/3

18:45-17:55

1 stop17h 10m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£565

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Fri 11/12

22:00-16:45

1 stop36h 45m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£568

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Fri 11/12

16:10-09:45

2 stops35h 35m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£574

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Sat 19/12

18:10-09:05

3 stops32h 55m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£587

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Wed 17/3

22:30-22:25

2 stops17h 55m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£589

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Sat 19/12

18:50-13:55

1 stop37h 05m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£600

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Tue 22/12

18:50-13:55

1 stop37h 05m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£603

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Fri 18/12

22:00-16:50

1 stop36h 50m

Frankfurt am Main

Wed 31/12

00:00-18:00

Nonstop0h 00m

£606

Panama CityFrankfurt am Main

PTY Panama City Tocumen Intl - FRA Frankfurt am Main

PTYFRA

Panama City Tocumen Intl

Mon 1/2

22:00-16:50

1 stop36h 50m

Frankfurt am Main

Mon 15/2

10:55-17:10

2 stops36h 15m

£747

Flights are sorted by cheapest return flights first.

Deals found on 3/11

Showing 1-10 of 20 resultsSorted by cheapest first
1
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Best time to book a flight from Panama City to Frankfurt

Have a flexible travel schedule? Discover the best time to fly to Frankfurt from Panama City with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Frankfurt am Main Airport

How far ahead should I book a flight from Panama City to Frankfurt am Main Airport?

The best time to book flights from Panama City to Frankfurt am Main Airport is 44 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Frankfurt am Main Airport?

Currently, November is the cheapest month in which you can book a flight from Panama City to Frankfurt am Main Airport (average of £621). Flying from Panama City to Frankfurt am Main Airport in January is currently the most expensive (average of £1,000). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Panama City to Frankfurt am Main Airport?

Airfare is typical for this route at the moment.

Panama City to Frankfurt am Main Airport flights typically cost between £504 and £933 in December.
The cheapest return price found within the last 5 days was £726 on Air Europa (1 Dec–21 Jan).

Related info for your journey

  • What airport do you fly from for flights from Panama City to Frankfurt am Main?

    If you book a flight to Frankfurt am Main from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Tocumen Intl to Frankfurt am Main per day from 0 different airlines.

  • How long is the flight from Panama City to Frankfurt am Main Airport?

    Turkish Airlines and United Airlines can get you from Panama City to Frankfurt am Main Airport in just under 21h 05m. Your travel time can differ by up to 15h 45m. Panama City and Frankfurt am Main Airport are separated by a distance of 5644 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Frankfurt that include hotel bookings?

    Yes. In addition to deals on Panama City to Frankfurt flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Frankfurt?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Frankfurt.

  • Can I find deals for business class flights from Panama City to Frankfurt?

    Yes. Cheapflights offers flight deals from Panama City to Frankfurt by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Frankfurt am Main Airport?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Frankfurt am Main Airport (average of £621). Flying from Panama City to Frankfurt am Main Airport in January is currently the most expensive (average of £1,000). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Frankfurt am Main Airport?

Book flights to Frankfurt am Main Airport if you plan to visit one of these locations
Wiesbaden
Bad Homburg
Mainz
Koblenz
Pforzheim
Heilbronn
Fulda
Bad Ems
Baden-Baden
Trier
Rothenburg ob der Tauber
Rüdesheim am Rhein

Browse thousands of different options on Cheapflights for your next trip

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