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Cheap flights from Manchester to Panama City from £330

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
28 Jun — 5 Jul1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 May 2026.

Mon 28/1206:10
MAN
-
PTY
2 stops28h 00m
United Airlines
Thu 14/110:00
PTY
-
MAN
2 stops25h 55m
United Airlines
Deal found 28/5£691
Thu 5/1109:30
MAN
-
PTY
2 stops39h 32m
United Airlines
Mon 9/1110:00
PTY
-
MAN
2 stops26h 00m
United Airlines
Deal found 24/5£692
Mon 8/606:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Sat 11/722:55
PTY
-
MAN
2 stops28h 55m
United Airlines
Deal found 28/5£700
Thu 24/906:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Sun 4/1015:30
PTY
-
MAN
2 stops43h 40m
United Airlines
Deal found 24/5£701
Wed 24/606:05
MAN
-
PTY
2 stops19h 26m
United Airlines
Wed 1/722:55
PTY
-
MAN
2 stops36h 25m
United Airlines
Deal found 25/5£701
Sat 11/706:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Sat 18/707:55
PTY
-
MAN
2 stops27h 25m
United Airlines
Deal found 27/5£702
Wed 12/806:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Mon 31/815:30
PTY
-
MAN
2 stops33h 00m
United Airlines
Deal found 27/5£704
Sun 16/809:00
MAN
-
PTY
2 stops40h 31m
United Airlines
Mon 31/815:30
PTY
-
MAN
2 stops33h 00m
United Airlines
Deal found 27/5£704
Sun 20/917:50
MAN
-
PTY
1 stop31h 55m
Multiple Airlines
Thu 1/1018:50
PTY
-
MAN
1 stop19h 15m
Multiple Airlines
Deal found 24/5£710
Sat 15/806:05
MAN
-
PTY
2 stops27h 59m
United Airlines
Mon 31/815:30
PTY
-
MAN
2 stops33h 00m
United Airlines
Deal found 27/5£729

Find flight deals from Manchester to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 May 2026.

Round-trip from

£691

One-way from

£330

Popular in

December

Cheapest in

September

Average price

£766
United Airlines
  • United Airlines
  • 5/11-9/11
  • 4 total stops
  • 65h 32m total
  • Manchester to Panama City
Search Deals
15/9
  • 15/9
  • 2 total stops
  • 41h 00m total
  • Manchester to Panama City
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£18 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 May 2026.
Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 5/11

09:30-20:02

2 stops39h 32m

Panama City Tocumen Intl

Mon 9/11

10:00-17:00

2 stops26h 00m

£692

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 8/6

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Sat 11/7

22:55-09:50

2 stops28h 55m

£700

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 9/7

06:05-04:04

2 stops27h 59m

Panama City Tocumen Intl

Thu 16/7

22:55-09:50

2 stops28h 55m

£700
Fastest return journey

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Fri 25/9

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Mon 5/10

09:45-17:10

2 stops25h 25m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 24/9

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Sun 4/10

15:30-17:10

2 stops43h 40m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 24/9

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Mon 5/10

09:45-17:10

2 stops25h 25m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 11/7

06:05-04:04

2 stops27h 59m

Panama City Tocumen Intl

Sat 18/7

22:55-09:50

2 stops28h 55m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 20/9

09:00-14:14

2 stops35h 14m

Panama City Tocumen Intl

Thu 1/10

09:45-17:20

2 stops25h 35m

£701

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sun 12/7

09:00-19:31

2 stops40h 31m

Panama City Tocumen Intl

Sun 19/7

09:45-17:20

2 stops25h 35m

£702

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Mon 17/8

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Mon 31/8

15:30-06:30

2 stops33h 00m

£704

Flights are sorted by cheapest return flights first.

Deals found on 24/5

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama City

What is the cheapest month to book a flight from Manchester to Panama City?

Currently, September is the cheapest month in which you can book a flight from Manchester to Panama City (average of £631). Flying from Manchester to Panama City in December is currently the most expensive (average of £862). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 29 May 2026.
Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Manchester to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,526 reviews
Check prices

Comfort

7.7

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7.8
Good
1,526 reviews
KLM
7.8
Good
1,526 reviews
Check prices

Comfort

7.7

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air France
7.4
Good
1,595 reviews
KLM
7.8
Good
1,526 reviews
Check prices

Comfort

7.7

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Turkish Airlines
7.4
Good
4,399 reviews
KLM
7.8
Good
1,526 reviews
Check prices

Comfort

7.7

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
United Airlines
7.4
Good
9,763 reviews
KLM
7.8
Good
1,526 reviews
Check prices

Comfort

7.7

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Lufthansa
6.8
Okay
8,032 reviews
KLM
7.8
Good
1,526 reviews
Check prices

Comfort

7.7

Boarding

7.8

Overall

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Panama City?

    A quick flight from Manchester to Panama City can take about 39h 32m. United Airlines provides one of the quickest options available for as low as £692. The distance from Manchester to Panama City is about 5182 mi.

  • What are the cheapest airlines flying from Manchester to Panama City round-trip?

    According to our current data, Air France (£562), Turkish Airlines (£577), and KLM (£601) offers the cheapest pricing from Manchester to Panama City. Air France is currently priced 25% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Manchester to Panama City (average of £631). Flying from Manchester to Panama City in December is currently the most expensive (average of £862). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Manchester to Panama City

Discover the top 5 airlines that operate flights from Manchester to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 May 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£562Average£707FlexibilityNo cancel feeOn-time77%
Search Air France flights
Turkish AirlinesCheapest£577Average£719FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
KLMCheapest£601Average£846FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£604Average£698FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£607Average£680FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama City?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama City from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Manchester.

Can Cheapflights find flights from Manchester to Panama City with no change fees?

Certainly. Search results for flights to Panama City from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to Panama City become cheaper?

Of course! You can now track prices for flights from Manchester to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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