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Cheap flights from Manchester to Panama City from £362

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
9 Sep — 16 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 August 2026.

Sat 5/906:05 -
2 stops19h 26m
Sat 12/915:30 -
2 stops43h 50m
Deal found 6/8£707
Wed 14/1006:05 -
2 stops19h 26m
Tue 3/1110:00 -
2 stops25h 15m
Deal found 10/8£708
Wed 21/1006:05 -
2 stops19h 26m
Mon 9/1110:00 -
2 stops26h 00m
Deal found 10/8£709
Fri 23/1009:00 -
2 stops40h 31m
Wed 4/1110:00 -
2 stops26h 00m
Deal found 10/8£710
Wed 14/1006:05 -
2 stops19h 26m
Sat 31/1015:41 -
2 stops35h 34m
Deal found 10/8£711
Fri 16/1009:00 -
2 stops40h 31m
Mon 2/1116:41 -
2 stops58h 34m
Deal found 10/8£712
Mon 26/1013:25 -
2 stops28h 34m
Tue 10/1115:30 -
1 stop14h 00m
Deal found 10/8£729
Tue 20/1010:35 -
2 stops38h 56m
Tue 3/1110:00 -
2 stops25h 15m
Deal found 10/8£731
Tue 20/1010:35 -
2 stops38h 56m
Thu 29/1009:30 -
2 stops19h 50m
Deal found 10/8£733
Thu 22/1006:05 -
2 stops19h 26m
Sun 8/1110:00 -
2 stops26h 00m
Deal found 10/8£734
Thu 15/1006:05 -
2 stops19h 26m
Wed 4/1110:00 -
2 stops19h 20m
Deal found 10/8£735
Thu 15/1006:05 -
2 stops19h 26m
Mon 2/1116:41 -
2 stops58h 34m
Deal found 10/8£735

Find flight deals from Manchester to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 August 2026.

Round-trip from

£707

One-way from

£364

Popular in

April

Cheapest in

September

Average price

£691
United Airlines
  • United Airlines
  • 5/9-12/9
  • 4 total stops
  • 63h 16m total
  • Manchester to Panama City
Search Deals
21/9
  • 21/9
  • 3 total stops
  • 32h 00m total
  • Manchester to Panama City
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£55 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 August 2026.
Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sat 5/9

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Sat 12/9

15:30-17:20

2 stops43h 50m

£707

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Fri 16/10

09:00-19:31

2 stops40h 31m

Panama City Tocumen Intl

Tue 3/11

10:00-16:15

2 stops25h 15m

£709

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Tue 8/9

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Mon 21/9

15:30-06:30

2 stops33h 00m

£709

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Mon 26/10

10:30-19:02

2 stops37h 32m

Panama City Tocumen Intl

Mon 9/11

10:00-17:00

2 stops26h 00m

£710

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Tue 20/10

10:35-19:31

2 stops38h 56m

Panama City Tocumen Intl

Wed 4/11

10:00-10:20

2 stops19h 20m

£733
Fastest return journey

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Thu 22/10

06:05-19:31

2 stops19h 26m

Panama City Tocumen Intl

Fri 6/11

10:00-17:00

2 stops26h 00m

£734

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Tue 12/1

10:45-20:05

1 stop38h 20m

Panama City Tocumen Intl

Sat 16/1

22:00-15:50

1 stop36h 50m

£755

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sat 16/1

12:40-17:05

2 stops33h 25m

Panama City Tocumen Intl

Wed 20/1

16:46-14:55

2 stops17h 09m

£838

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Wed 21/10

10:40-12:59

1 stop32h 19m

Panama City Tocumen Intl

Thu 5/11

15:24-10:05

2 stops37h 41m

£845

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sat 16/1

22:30-17:10

2 stops23h 40m

Panama City Tocumen Intl

Wed 20/1

22:00-15:50

1 stop36h 50m

£850

Flights are sorted by cheapest return flights first.

Deals found on 7/8

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama City

What is the cheapest month to book a flight from Manchester to Panama City?

Currently, September is the cheapest month in which you can book a flight from Manchester to Panama City (average of £635). Flying from Manchester to Panama City in April is currently the most expensive (average of £877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 10 August 2026.
Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Manchester to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,555 reviews
Check prices

Overall

7.8

Comfort

7.7

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
KLM
7.8
Good
1,555 reviews
KLM
7.8
Good
1,555 reviews
Check prices

Overall

7.8

Comfort

7.7

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
Air France
7.5
Good
1,639 reviews
KLM
7.8
Good
1,555 reviews
Check prices

Overall

7.8

Comfort

7.7

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
Turkish Airlines
7.4
Good
4,479 reviews
KLM
7.8
Good
1,555 reviews
Check prices

Overall

7.8

Comfort

7.7

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle
United Airlines
7.4
Good
10,095 reviews
KLM
7.8
Good
1,555 reviews
Check prices

Overall

7.8

Comfort

7.7

Boarding

7.8

Crew

8.4

Food

7.3

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Panama City?

    A quick flight from Manchester to Panama City can take about 19h 26m. United Airlines provides one of the quickest options available for as low as £707. The distance from Manchester to Panama City is about 5182 mi.

  • What are the cheapest airlines flying from Manchester to Panama City round-trip?

    According to our current data, Turkish Airlines (£522), KLM (£597), and Air France (£603) offers the cheapest pricing from Manchester to Panama City. Turkish Airlines is currently priced 32% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Manchester to Panama City (average of £635). Flying from Manchester to Panama City in April is currently the most expensive (average of £877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Manchester to Panama City

Discover the top 4 airlines that operate flights from Manchester to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 August 2026.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest£522Average£720FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
KLMCheapest£597Average£899FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapest£603Average£763FlexibilityNo cancel feeOn-time77%
Search Air France flights
United AirlinesCheapest£607Average£696FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama City?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama City from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Manchester.

Can Cheapflights find flights from Manchester to Panama City with no change fees?

Certainly. Search results for flights to Panama City from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to Panama City become cheaper?

Of course! You can now track prices for flights from Manchester to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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