What’s the cheapest stopover airport for flights from Manchester to Panama City?

Istanbul (IST) is the most affordable one-stop option, with an average return flight price of £900.

What’s the top stopover airport for flights from Manchester to Panama City?

Amsterdam (AMS) – chosen by Cheapflights users on 55% of one-stop itineraries from Manchester to Panama City on Cheapflights.

What’s the fastest stopover option from Manchester to Panama City?

Flights via Amsterdam (AMS) have the shortest average one-way travel time for one-stop routes: 14h 50m.

Which airport typically offers the quickest stopover for flights from Manchester to Panama City?

Flights via Amsterdam (AMS) offer the fastest connection on this route, with an average stopover time of 2h 36m.

How long is the flight from Manchester to Panama City?

A quick flight from Manchester to Panama City can take about 18h 52m. United Airlines provides one of the quickest options available for as low as £723. The distance from Manchester to Panama City is about 5182 mi.

What are the cheapest airlines flying from Manchester to Panama City round-trip?

According to our current data, Turkish Airlines (£532), Air France (£614), and United Airlines (£652) offers the cheapest pricing from Manchester to Panama City. Turkish Airlines is currently priced 36% below the average price you’ll pay for this route.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

What are the most popular airlines that fly from Manchester to Panama City?

KLM, Air France and United Airlines are the most popular airlines when flying from Manchester to Panama City.

What is the cheapest time of day to fly from MAN to PTY?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Manchester to Panama City as you normally would.

Can I find deals for flights from Manchester to Panama City that include hotel bookings?

Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Manchester to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

Can I find deals for business class flights from Manchester to Panama City?

Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£339+ Cheap Flights from Manchester to Panama City

Cheap flight deals from Manchester to Panama City

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 October 2026.

Mon 2/1106:10 -

2 stops18h 52m

Mon 16/1110:00 -

2 stops19h 20m

Deal found 11/10£723

Sat 14/1106:10 -

2 stops18h 52m

Sat 21/1116:41 -

2 stops35h 04m

Deal found 14/10£724

Fri 27/1111:00 -

1 stop14h 20m

Fri 4/1222:30 -

1 stop18h 00m

Deal found 13/10£733

Fri 27/1105:50 -

2 stops19h 30m

Fri 4/1221:55 -

1 stop13h 40m

Deal found 13/10£759

Fri 27/1105:50 -

2 stops19h 30m

Fri 4/1221:55 -

2 stops18h 35m

Deal found 13/10£793

Sat 28/1111:30 -

2 stops37h 32m

Sat 5/1210:00 -

2 stops41h 45m

Deal found 14/10£800

Wed 4/1110:45 -

2 stops35h 25m

Wed 18/1122:00 -

1 stop36h 50m

Deal found 11/10£817

Sun 8/1106:00 -

2 stops36h 31m

Sun 15/1119:28 -

2 stops35h 02m

Deal found 14/10£830

Tue 27/1020:40 -

2 stops33h 40m

Tue 17/1116:18 -

2 stops18h 47m

Deal found 13/10£838

Wed 21/1006:05 -

2 stops19h 26m

Mon 2/1122:29 -

2 stops32h 01m

Deal found 10/10£840

Sat 14/1111:30 -

1 stop31h 43m

Sat 21/1118:38 -

1 stop33h 07m

Deal found 14/10£855

Find flight deals from Manchester to Panama City

Round-trip from	£723
One-way from	£339
Popular in	July
Cheapest in	August
Average price	£709

United Airlines
2/11-16/11
4 total stops
38h 12m total
Manchester to Panama City

Search Deals

6/2-31/12
3 total stops
21h 30m total
Manchester to Panama City

Search Deals

Highest demand for flights based on searches. 1% potential increase in price (£12 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (£12 potential savings vs. average return price).

Search Deals

Average for round-trip flights in October 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sat 6/2

16:40-09:10

3 stops21h 30m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£339

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sun 11/4

14:30-09:15

2 stops24h 45m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£352

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Wed 7/4

06:50-00:35

3 stops23h 45m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£398

Fastest return journey

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Fri 9/4

08:55-16:50

1 stop13h 55m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£475

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sun 11/4

06:00-16:50

1 stop16h 50m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£475

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Tue 6/4

20:45-16:50

1 stop26h 05m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£475

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Sat 5/12

09:05-05:48

3 stops25h 43m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£723

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Thu 26/11

06:10-20:02

2 stops18h 52m

Panama City Tocumen Intl

Thu 3/12

10:00-10:20

2 stops19h 20m

£723

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Wed 10/2

06:10-20:02

2 stops18h 52m

Panama City Tocumen Intl

Wed 24/2

10:00-10:20

2 stops19h 20m

£723

ManchesterPanama City

MAN Manchester - PTY Panama City Tocumen Intl

MANPTY

Manchester

Wed 4/11

06:10-20:02

2 stops18h 52m

Panama City Tocumen Intl

Wed 18/11

10:00-10:20

2 stops19h 20m

£723

Flights are sorted by cheapest return flights first.

Deals found on 12/10

Showing 1-10 of 16 resultsSorted by cheapest first

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.

MAN-PTY

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama City

Prices

Currently, August is the cheapest month in which you can book a flight from Manchester to Panama City (average of £705). Flying from Manchester to Panama City in July is currently the most expensive (average of £999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Manchester to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

KLM

7.8

Good

1,588 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Artem,Oct 2026

FCO - AMS

Having to wait 2 hours in line just to get a boarding pass with no checked baggage is unacceptable for a modern airport. Receiving only 2 out of 9 boarding passes and then having to wait another 2 hours for the remaining ones is a disaster.

KLM

7.8

Good

1,588 reviews

KLM

7.8

Good

1,588 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Artem,Oct 2026

FCO - AMS

Air France

7.5

Good

1,651 reviews

KLM

7.8

Good

1,588 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Artem,Oct 2026

FCO - AMS

Turkish Airlines

7.4

Good

4,455 reviews

KLM

7.8

Good

1,588 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Artem,Oct 2026

FCO - AMS

United Airlines

7.4

Good

10,362 reviews

KLM

7.8

Good

1,588 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Artem,Oct 2026

FCO - AMS

Related info for your journey

How long is the flight from Manchester to Panama City?
A quick flight from Manchester to Panama City can take about 18h 52m. United Airlines provides one of the quickest options available for as low as £723. The distance from Manchester to Panama City is about 5182 mi.
What are the cheapest airlines flying from Manchester to Panama City round-trip?
According to our current data, Turkish Airlines (£532), Air France (£614), and United Airlines (£652) offers the cheapest pricing from Manchester to Panama City. Turkish Airlines is currently priced 36% below the average price you’ll pay for this route.
Can I find deals for flights from Manchester to Panama City that include hotel bookings?
Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Manchester to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.
Can I find deals for business class flights from Manchester to Panama City?
Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester to Panama City?
Currently, August is the cheapest month in which you can book a flight from Manchester to Panama City (average of £705). Flying from Manchester to Panama City in July is currently the most expensive (average of £999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

San Blas

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Flights by cabin class

Other flight options

Other flights from Manchester

Panama City flight routes

Popular flights

Alternative routes for Manchester to Panama City

Heathrow to Panama City flights

Gatwick to Panama City flights

Stansted to Panama City flights

London City to Panama City flights

Luton to Panama City flights

Birmingham to Panama City flights

Newcastle upon Tyne to Panama City flights

Edinburgh to Panama City flights

Leeds to Panama City flights

Top 4 airlines flying from Manchester to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Turkish Airlines	Cheapest£532	Average£795	FlexibilityNo cancel fee	On-time77%	Search Turkish Airlines flights
Air France	Cheapest£614	Average£784	FlexibilityNo cancel fee	On-time77%	Search Air France flights
United Airlines	Cheapest£652	Average£737	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights
KLM	Cheapest£681	Average£936	FlexibilityNo cancel fee	On-time75%	Search KLM flights

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to Panama City?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama City from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Manchester.

Can Cheapflights find flights from Manchester to Panama City with no change fees?

Certainly. Search results for flights to Panama City from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to Panama City become cheaper?

Of course! You can now track prices for flights from Manchester to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Manchester to Panama City from £339

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Manchester to Panama City

Cheapest flights from Manchester to Panama CityExplore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 October 2026.

Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 October 2026.

Best flights from Manchester to Panama CityDiscover carefully curated flight deals from Manchester to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 14 October 2026.

Discover carefully curated flight deals from Manchester to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 14 October 2026.

Last-minute flights from Manchester to Panama CityDiscover last-minute flight deals from Manchester to Panama City. Data last updated 14 October 2026 and is based on user searches.

Discover last-minute flight deals from Manchester to Panama City. Data last updated 14 October 2026 and is based on user searches.

One-way flights from Manchester to Panama CitySearch for one-way flight options from Manchester to Panama City. Find affordable one-way fares based on user searches. Data last updated 14 October 2026.

Search for one-way flight options from Manchester to Panama City. Find affordable one-way fares based on user searches. Data last updated 14 October 2026.

Find flight deals from Manchester to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Manchester to Panama City?

What’s the top stopover airport for flights from Manchester to Panama City?

Amsterdam (AMS) – chosen by Cheapflights users on 55% of one-stop itineraries from Manchester to Panama City on Cheapflights.

What’s the cheapest stopover airport for flights from Manchester to Panama City?

Istanbul (IST) is the most affordable one-stop option, with an average return flight price of £900.

What’s the fastest stopover option from Manchester to Panama City?

Flights via Amsterdam (AMS) have the shortest average one-way travel time for one-stop routes: 14h 50m.

Which airport typically offers the quickest stopover for flights from Manchester to Panama City?

Flights via Amsterdam (AMS) offer the fastest connection on this route, with an average stopover time of 2h 36m.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Manchester to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

How long is the flight from Manchester to Panama City?

What are the cheapest airlines flying from Manchester to Panama City round-trip?

Can I find deals for flights from Manchester to Panama City that include hotel bookings?

How can I find direct flights from Manchester to Panama City?

Can I find deals for business class flights from Manchester to Panama City?

What is the cheapest month to book a flight from Manchester to Panama City?

Travelling to a place near Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Panama City by adding a car hire and/or hotel booking to your travel itinerary.

Search flights from Manchester to Panama City by cabin class

Find flights from Manchester to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Manchester and Panama City flights

Browse other Manchester and Panama City flight options. Last updated on 14 October 2026.

Other flights from Manchester

Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on 14 October 2026.

Other flights to Panama City

Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 14 October 2026.

Popular flight searches

Check out other popular destinations found by fellow travellers in 2026

Top 4 airlines flying from Manchester to Panama City

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to Panama City?

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama City?

Can Cheapflights find flights from Manchester to Panama City with no change fees?

Can Cheapflights notify me if prices for flights from Manchester to Panama City become cheaper?

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 October 2026.

Best flights from Manchester to Panama City
Discover carefully curated flight deals from Manchester to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 14 October 2026.

Last-minute flights from Manchester to Panama City
Discover last-minute flight deals from Manchester to Panama City. Data last updated 14 October 2026 and is based on user searches.

One-way flights from Manchester to Panama City
Search for one-way flight options from Manchester to Panama City. Find affordable one-way fares based on user searches. Data last updated 14 October 2026.