Find flights
When to book
Airlines
FAQs

Cheap flights from Manchester to Panama City from £303

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — PTY
20 Feb — 27 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Panama City
Explore the most affordable flight options available from Manchester to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 January 2026.

Sun 25/113:40
MAN
-
PTY
1 stop35h 15m
KLM
Thu 29/118:45
PTY
-
MAN
1 stop32h 35m
KLM
Deal found 19/1£639
Sun 15/206:00
MAN
-
PTY
2 stops42h 38m
United Airlines
Tue 24/216:41
PTY
-
MAN
2 stops41h 09m
United Airlines
Deal found 19/1£640
Wed 4/222:25
MAN
-
PTY
2 stops23h 40m
Turkish Airlines
Wed 11/221:45
PTY
-
MAN
1 stop34h 20m
Turkish Airlines
Deal found 19/1£655
Wed 11/322:25
MAN
-
PTY
2 stops23h 40m
Turkish Airlines
Mon 16/318:45
PTY
-
MAN
1 stop34h 05m
Turkish Airlines
Deal found 20/1£657
Thu 7/505:55
MAN
-
PTY
2 stops38h 19m
United Airlines
Mon 11/509:45
PTY
-
MAN
2 stops18h 40m
United Airlines
Deal found 18/1£661
Tue 10/311:05
MAN
-
PTY
1 stop14h 05m
Air France
Mon 16/322:20
PTY
-
MAN
1 stop30h 50m
Air France
Deal found 20/1£663
Mon 16/206:00
MAN
-
PTY
2 stops40h 07m
United Airlines
Wed 25/210:00
PTY
-
MAN
2 stops21h 20m
United Airlines
Deal found 19/1£665
Fri 6/222:25
MAN
-
PTY
2 stops23h 40m
Turkish Airlines
Wed 11/221:45
PTY
-
MAN
1 stop31h 05m
Turkish Airlines
Deal found 19/1£665
Mon 9/306:00
MAN
-
PTY
2 stops39h 07m
United Airlines
Mon 16/315:41
PTY
-
MAN
2 stops39h 39m
United Airlines
Deal found 20/1£666
Sat 7/314:05
MAN
-
PTY
2 stops32h 00m
Turkish Airlines
Wed 25/321:45
PTY
-
MAN
1 stop18h 40m
Turkish Airlines
Deal found 20/1£687

Find flight deals from Manchester to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 January 2026.

Round-trip from

£640

One-way from

£303

Popular in

December

Cheapest in

September

Average price

£772
United Airlines
  • United Airlines
  • 15/2-28/2
  • 4 total stops
  • 81h 17m total
  • Manchester to Panama City
Search Deals
9/2
  • 9/2
  • 2 total stops
  • 45h 00m total
  • Manchester to Panama City
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£34 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2026.
Use the filters below to find and compare flights from Manchester to Panama City that are best for you.

Fly from

Manchester

Fly to

Panama City

Route

Depart

Return

Price

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Wed 4/2

06:00-19:38

2 stops42h 38m

Panama City Tocumen Intl

Wed 11/2

16:41-12:20

2 stops38h 39m

£640

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 3/2

09:25-17:07

2 stops36h 42m

Panama City Tocumen Intl

Wed 11/2

16:41-12:20

2 stops38h 39m

£640

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 19/2

06:00-19:38

2 stops42h 38m

Panama City Tocumen Intl

Tue 24/2

16:41-12:20

2 stops38h 39m

£640

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 7/5

05:55-14:14

2 stops38h 19m

Panama City Tocumen Intl

Mon 11/5

09:45-10:25

2 stops18h 40m

£661

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 10/3

11:05-20:10

1 stop14h 05m

Panama City Tocumen Intl

Mon 16/3

22:20-10:10

1 stop30h 50m

£663

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 10/3

06:00-16:07

2 stops39h 07m

Panama City Tocumen Intl

Mon 16/3

15:41-12:20

2 stops39h 39m

£666

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 7/3

16:50-17:05

2 stops29h 15m

Panama City Tocumen Intl

Tue 24/3

18:45-09:50

1 stop34h 05m

£687

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Tue 10/3

09:05-20:10

2 stops16h 05m

Panama City Tocumen Intl

Mon 16/3

22:20-10:10

1 stop30h 50m

£687

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Sat 7/3

14:05-17:05

2 stops32h 00m

Panama City Tocumen Intl

Wed 25/3

21:45-15:50

1 stop37h 05m

£689

ManchesterPanama City

MAN - PTY

MANPTY

Manchester

Thu 19/2

09:25-17:07

2 stops36h 42m

Panama City Tocumen Intl

Mon 23/2

16:41-08:40

2 stops58h 59m

£691

Flights are sorted by cheapest return flights first.

Deals found on 19/1

Showing 1-10 of 18 results
1
2

Best time to book a flight from Manchester to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama City

How far ahead should I book a flight from Manchester to Panama City?

Use this chart to determine the optimal time to book a return flight from Manchester to Panama City. Price data was last updated on 16 January 2026.

Booking 86 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Manchester to Panama City?

Currently, May is the cheapest month in which you can book a flight from Manchester to Panama City (average of £518). Flying from Manchester to Panama City in December is currently the most expensive (average of £693). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 21 January 2026.
Get a feel of what it's like to fly with KLM, Air France, andUnited Airlines from Manchester to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.6

Entertainment

7.1

Overall

7.7

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7.7
Good
1,442 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.6

Entertainment

7.1

Overall

7.7

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Air France
7.4
Good
1,524 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.6

Entertainment

7.1

Overall

7.7

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
United Airlines
7.4
Good
9,184 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.6

Entertainment

7.1

Overall

7.7

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Turkish Airlines
7.3
Good
4,198 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.6

Entertainment

7.1

Overall

7.7

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Lufthansa
6.8
Okay
7,733 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.6

Entertainment

7.1

Overall

7.7

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Panama City?

    A quick flight from Manchester to Panama City can take about 42h 38m. United Airlines provides one of the quickest options available for as low as £640. The distance from Manchester to Panama City is about 5182 mi.

  • What are the cheapest airlines flying from Manchester to Panama City round-trip?

    According to our current data, Air France (£561), KLM (£578), and United Airlines (£604) offers the cheapest pricing from Manchester to Panama City. Air France is currently priced 22% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Panama City that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama City.

  • Can I find deals for business class flights from Manchester to Panama City?

    Yes. Cheapflights offers flight deals from Manchester to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Manchester to Panama City (average of £518). Flying from Manchester to Panama City in December is currently the most expensive (average of £693). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Manchester to Panama City

Discover the top 5 airlines that operate flights from Manchester to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest£561Average£710FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£578Average£817FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£604Average£693FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Turkish AirlinesCheapest£624Average£717FlexibilityNo cancel feeOn-time77%
Search Turkish Airlines flights
LufthansaCheapest£627Average£674FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Panama City?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama City from Manchester today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Manchester to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Manchester.

Can Cheapflights find flights from Manchester to Panama City with no change fees?

Certainly. Search results for flights to Panama City from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to Panama City become cheaper?

Of course! You can now track prices for flights from Manchester to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.