Cheap flights from Mexico City to Panama City from £95
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
27 Dec — 3 Jan1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in July or August, booked 90 days in advance, depart on a Monday or Wednesday and return on a Monday
Cheap flight deals from Mexico City to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 27 November 2025.
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 27 November 2025.
Thu 4/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Fri 12/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 25/11£250
Mon 15/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£259
Sun 7/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Tue 16/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£260
Fri 5/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Mon 8/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 25/11£272
Mon 29/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Tue 13/109:21PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 27/11£275
Tue 16/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£279
Tue 2/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 22/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£282
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Wed 31/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£286
Wed 3/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Wed 21/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Deal found 25/11£286
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 22/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£287
Thu 11/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Mon 15/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 25/11£289
Mon 15/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Mon 22/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£291
Best flights from Mexico City to Panama City
Discover carefully curated flight deals from Mexico City to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 27 November 2025.
Sun 11/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 19/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Deal found 27/11£275
Thu 18/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Sun 28/1209:03PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£286
Sat 13/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Mon 22/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 24/11£286
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Sat 27/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 25/11£286
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Wed 31/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£286
Tue 16/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Tue 30/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£286
Thu 11/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Sun 14/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 26/11£289
Tue 20/115:30MEX - PTY
Nonstop3h 37mCopa Airlines
Sun 25/111:47PTY - MEX
Nonstop3h 43mCopa Airlines
Deal found 26/11£291
Sat 20/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Thu 8/111:47PTY - MEX
Nonstop3h 43mCopa Airlines
Deal found 26/11£291
Tue 24/201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Wed 4/321:26PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 26/11£291
Tue 10/201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Fri 20/209:21PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 27/11£291
Direct flights from Mexico City to Panama City
Explore direct flight options from Mexico City to Panama City based on user searches, and compare prices and availability for your desired travel dates. Data last updated 27 November 2025.
Mon 15/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£259
Sun 7/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Tue 16/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£260
Sat 10/115:30MEX - PTY
Nonstop3h 37mCopa Airlines
Sat 17/109:21PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 25/11£275
Fri 2/108:55MEX - PTY
Nonstop3h 45mAeromexico
Fri 9/115:00PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£276
Tue 16/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£279
Wed 10/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Fri 19/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 24/11£282
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Wed 31/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£286
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 22/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£287
Thu 11/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Mon 15/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 25/11£289
Sat 10/102:00MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 19/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Deal found 25/11£291
Mon 22/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Mon 29/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 25/11£293
Thu 18/1208:55MEX - PTY
Nonstop3h 45mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£295
Last-minute flights from Mexico City to Panama City
Discover last-minute flight deals from Mexico City to Panama City. Data last updated 27 November 2025 and is based on user searches.
Tue 2/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 22/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£282
Wed 3/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Wed 21/122:13PTY - MEX
Nonstop3h 47mCopa Airlines
Deal found 25/11£286
Thu 4/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Fri 12/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 25/11£250
Fri 5/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Mon 8/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 25/11£272
Sun 7/1213:10MEX - PTY
Nonstop3h 46mCopa Airlines
Tue 16/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£260
Thu 11/1201:20MEX - PTY
Nonstop3h 40mCopa Airlines
Mon 15/1222:14PTY - MEX
Nonstop3h 46mCopa Airlines
Deal found 25/11£289
Mon 15/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£259
Mon 15/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Mon 22/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£291
Tue 16/1208:40MEX - PTY
Nonstop3h 52mAeromexico
Wed 24/1214:55PTY - MEX
Nonstop4h 05mAeromexico
Deal found 26/11£279
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Wed 31/1211:38PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£286
Wed 17/1202:00MEX - PTY
Nonstop3h 41mCopa Airlines
Mon 22/1209:18PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 26/11£287
Mon 29/1215:30MEX - PTY
Nonstop3h 45mCopa Airlines
Tue 13/109:21PTY - MEX
Nonstop3h 49mCopa Airlines
Deal found 27/11£275
One-way flights from Mexico City to Panama City
Search for one-way flight options from Mexico City to Panama City. Find affordable one-way fares based on user searches. Data last updated 27 November 2025.
Thu 1/109:25MEX - PTY
Nonstop3h 41mCopa Airlines
Deal found 26/11£95
Tue 17/223:10MEX - PTY
1 stop13h 50mAvianca
Deal found 25/11£127
Thu 8/101:20MEX - PTY
Nonstop3h 40mCopa Airlines
Deal found 25/11£151
Tue 6/116:50MEX - PTY
2 stops21h 05mAvianca
Deal found 25/11£245
Sun 4/104:00MEX - PTY
2 stops9h 55mAvianca
Deal found 25/11£264
Cheapflights Fare Finder
Customise your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 27 November 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.
Fly from
Mexico City
Fly to
Panama City
Route
Depart
Return
Price
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Sun 11/1
09:25-14:06
Nonstop3h 41m
Panama City Tocumen Intl
Mon 19/1
22:13-01:00
Nonstop3h 47m
£275
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Thu 18/12
02:00-06:41
Nonstop3h 41m
Panama City Tocumen Intl
Sun 28/12
09:03-11:55
Nonstop3h 52m
£286
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Sat 13/12
01:20-06:00
Nonstop3h 40m
Panama City Tocumen Intl
Mon 22/12
22:14-01:00
Nonstop3h 46m
£286
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Wed 17/12
02:00-06:41
Nonstop3h 41m
Panama City Tocumen Intl
Sat 27/12
11:38-14:30
Nonstop3h 52m
£286
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Wed 17/12
02:00-06:41
Nonstop3h 41m
Panama City Tocumen Intl
Wed 31/12
11:38-14:30
Nonstop3h 52m
£286
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Tue 16/12
01:20-06:00
Nonstop3h 40m
Panama City Tocumen Intl
Tue 30/12
09:18-12:10
Nonstop3h 52m
£286
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Thu 11/12
01:20-06:00
Nonstop3h 40m
Panama City Tocumen Intl
Sun 14/12
22:14-01:00
Nonstop3h 46m
£289
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Tue 20/1
15:30-20:07
Nonstop3h 37m
Panama City Tocumen Intl
Sun 25/1
11:47-14:30
Nonstop3h 43m
£291
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Sat 20/12
01:20-06:00
Nonstop3h 40m
Panama City Tocumen Intl
Thu 8/1
11:47-14:30
Nonstop3h 43m
£291
Mexico CityPanama City
MEX - PTY
MEXPTY
Mexico City Benito Juarez
Tue 24/2
01:20-06:00
Nonstop3h 40m
Panama City Tocumen Intl
Wed 4/3
21:26-00:15
Nonstop3h 49m
£291
Flights are sorted by cheapest return flights first.
Deals found on 26/11
Showing 1-10 of 17 results
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Best time to book a flight from Mexico City to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mexico City to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Mexico City to Panama City?
Use this chart to determine the optimal time to book a return flight from Mexico City to Panama City. Price data was last updated on 21 November 2025.
The best time to book flights from Mexico City to Panama City is 90 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Mexico City to Panama City?
Currently, September is the cheapest month in which you can book a flight from Mexico City to Panama City (average of £133). Flying from Mexico City to Panama City in April is currently the most expensive (average of £286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MEX to PTY?
Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 27 November 2025.
One of the essential ways to save on airfare from Mexico City to Panama City is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at midday could potentially save you up to 39% on airfare.
How much does it cost for a return flight from Mexico City to Panama City?
Weekly flight availability from Mexico City to Panama City
Explore weekly flight availability from Mexico City to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 27 November 2025.
The most flights from MEX to PTY are scheduled on a Monday (10 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (8 on average).
How often are flights from Mexico City to Panama City delayed?
About 3% of weekly flights between Mexico City and Panama City have experienced delays in the past year, with the average delay time being 137 minutes.
What is the most punctual flight time for Mexico City to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Mexico City to Panama City flights?
Over the past year, Copa Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 27 November 2025.
Get a feel of what it's like to fly with Copa Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Related info for your journey
Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Mexico City to Panama City?
If you book a flight from Mexico City to Panama City, you will be flying from Benito Juarez to Tocumen Intl. Flights to Panama City Tocumen Intl (PTY) from Mexico City Benito Juarez (MEX) take 3h 40m for a nonstop flight. There are 9 flights from Benito Juarez to Panama City per day from 1 airline.
How popular is this Mexico City to Panama City flight route?
The Mexico City Benito Juarez to Panama City Tocumen Intl flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Mexico City to Panama City?
For as low as £286, Copa Airlines can have you in Panama City from Mexico City in 3h 41m. The distance between Mexico City and Panama City is about 1497 mi. All flights are typically direct.
What is the cheapest airline to fly from Mexico City to Panama City round-trip?
Currently priced at £267, Copa Airlines will fly you from Mexico City to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Copa Airlines is currently priced 11% below the average price you’ll pay for this route.
What are the most reliable airlines from Mexico City to Panama City?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mexico City to Panama City on time: Copa Airlines (90%), Emirates (89%), AeroMexico Connect (87%).
What are the cheapest flights from Mexico City to Panama City?
Looking for the cheapest flight from Mexico City to Panama City? While on average our users pay £311, our data indicates the cheapest price to be £232. The most popular route (Mexico City Benito Juarez - Panama City Tocumen Intl), is priced around £333.
Can I find deals for flights from Mexico City to Panama City that include hotel bookings?
Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Mexico City to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.
Can I find deals for business class flights from Mexico City to Panama City?
Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mexico City to Panama City?
Currently, September is the cheapest month in which you can book a flight from Mexico City to Panama City (average of £133). Flying from Mexico City to Panama City in April is currently the most expensive (average of £286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Browse through other flights departing from Mexico City. Flights are based on user searches made on Cheapflights and were last updated on 27 November 2025.
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 27 November 2025.
Top airline flying from Mexico City to Panama City
Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 27 November 2025.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Mexico City to Panama City?
Cheapflights makes it easy to find Mexico City to Panama City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Mexico City to Panama City?
By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Mexico City.
Can Cheapflights find flights from Mexico City to Panama City with no change fees?
Users can book flights with no change fees policies with our dedicated filters. Book flights from Mexico City to Panama City flexibly with Cheapflights today.
Can Cheapflights notify me if prices for flights from Mexico City to Panama City become cheaper?
Yes! Start tracking prices for Mexico City to Panama City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.
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