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Cheap flights from Prague to San Diego from £667

PRG — SAN
7 Oct — 14 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Prague to San Diego

Enter your travel dates to find the best prices.

Cheapest flights from Prague to San Diego

Fri 18/914:30 -
1 stop30h 20m
Tue 29/911:30 -
2 stops18h 30m
Deal found 4/9£686
Tue 20/1006:00 -
1 stop14h 50m
Tue 27/1006:25 -
2 stops20h 45m
Deal found 5/9£686
Tue 20/1006:00 -
1 stop14h 50m
Tue 27/1015:20 -
1 stop20h 10m
Deal found 5/9£689
Fri 18/911:00 -
1 stop21h 34m
Mon 28/906:15 -
2 stops17h 05m
Deal found 4/9£697
Thu 17/912:00 -
2 stops19h 10m
Mon 28/913:00 -
2 stops23h 25m
Deal found 4/9£732
Tue 15/910:15 -
1 stop19h 36m
Thu 1/1016:45 -
1 stop32h 25m
Deal found 4/9£763
Tue 15/910:15 -
1 stop19h 36m
Mon 28/906:20 -
1 stop16h 55m
Deal found 4/9£768
Thu 17/909:10 -
2 stops18h 25m
Mon 28/917:15 -
1 stop13h 45m
Deal found 4/9£768

Find flight deals from Prague to San Diego

Round-trip from

£686

One-way from

£667

Popular in

September

Cheapest in

March

Average price

£1,095
Delta
  • Delta
  • 22/10-29/10
  • 3 total stops
  • 35h 35m total
  • Prague to San Diego
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British Airways
  • British Airways
  • 19/10-31/12
  • 1 total stop
  • 16h 25m total
  • Prague to San Diego
Search Deals
Highest demand for flights based on searches. 15% potential increase in price (£110 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£20 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Prague to San Diego that are best for you.

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Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Mon 19/10

10:25-17:50

1 stop16h 25m

San Diego

Wed 31/12

00:00-09:00

Nonstop0h 00m

£667

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Thu 22/10

06:00-11:50

1 stop14h 50m

San Diego

Thu 29/10

06:25-11:10

2 stops20h 45m

£686

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Tue 20/10

06:00-11:50

1 stop14h 50m

San Diego

Tue 27/10

06:25-11:10

2 stops20h 45m

£686

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Tue 20/10

06:00-11:50

1 stop14h 50m

San Diego

Tue 27/10

15:20-19:30

1 stop20h 10m

£689

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Thu 22/10

06:00-11:50

1 stop14h 50m

San Diego

Thu 29/10

15:05-17:35

1 stop18h 30m

£689

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Sat 19/9

10:15-20:51

1 stop19h 36m

San Diego

Tue 29/9

09:46-23:25

2 stops28h 39m

£763

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Fri 18/9

10:15-20:51

1 stop19h 36m

San Diego

Fri 25/9

11:15-22:50

2 stops26h 35m

£763

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Sat 19/9

10:15-20:51

1 stop19h 36m

San Diego

Mon 28/9

10:11-22:50

2 stops27h 39m

£763

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Thu 5/11

07:05-22:27

2 stops24h 22m

San Diego

Mon 9/11

14:30-16:05

2 stops16h 35m

£797

PragueSan Diego

PRG Václav Havel Prague - SAN San Diego

PRGSAN

Václav Havel Prague

Mon 21/12

21:35-16:10

1 stop27h 35m

San Diego

Sun 27/12

18:00-20:40

1 stop17h 40m

£800

Flights are sorted by cheapest return flights first.

Deals found on 3/9

Showing 1-10 of 14 resultsSorted by cheapest first
1
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Best time to book a flight from Prague to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Prague with our price prediction graph.
Estimated return price

Related info for your journey

  • How long is the flight from Prague to San Diego?

    A quick flight from Prague to San Diego can take about 14h 50m. Delta provides one of the quickest options available for as low as £686. Prague and San Diego are separated by a distance of 5986 mi.

  • Can I find deals for flights from Prague to San Diego that include hotel bookings?

    Yes. In addition to deals on Prague to San Diego flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Prague to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to San Diego.

  • Can I find deals for business class flights from Prague to San Diego?

    Yes. Cheapflights offers flight deals from Prague to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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When you search for this flight from Prague to San Diego, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

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By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to San Diego from Prague.

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Users can book flights with no change fees policies with our dedicated filters. Book flights from Prague to San Diego flexibly with Cheapflights today.

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