Cheap flights from Manchester to Santiago from £373

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — SCL
14 Apr — 21 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Santiago
Explore the most affordable flight options available from Manchester to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 March 2026.

Tue 24/1106:00
MAN
-
SCL
2 stops27h 00m
Multiple Airlines
Tue 8/1208:55
SCL
-
MAN
2 stops26h 55m
Multiple Airlines
Deal found 12/3£804
Mon 6/723:30
MAN
-
SCL
2 stops38h 00m
Turkish Airlines
Sun 20/911:15
SCL
-
MAN
2 stops44h 50m
Turkish Airlines
Deal found 10/3£818
Mon 2/1123:15
MAN
-
SCL
2 stops37h 40m
Turkish Airlines
Mon 23/1111:40
SCL
-
MAN
2 stops43h 10m
Turkish Airlines
Deal found 10/3£829
Wed 29/423:30
MAN
-
SCL
2 stops38h 00m
Turkish Airlines
Mon 18/510:15
SCL
-
MAN
2 stops44h 50m
Turkish Airlines
Deal found 11/3£840
Wed 16/923:30
MAN
-
SCL
2 stops38h 00m
Turkish Airlines
Wed 7/1011:15
SCL
-
MAN
2 stops44h 50m
Turkish Airlines
Deal found 13/3£844
Sat 26/923:30
MAN
-
SCL
2 stops38h 00m
Turkish Airlines
Thu 1/1011:15
SCL
-
MAN
2 stops44h 50m
Turkish Airlines
Deal found 12/3£856
Wed 13/510:40
MAN
-
SCL
2 stops26h 50m
Turkish Airlines
Mon 25/510:15
SCL
-
MAN
2 stops25h 15m
Turkish Airlines
Deal found 12/3£865
Wed 13/518:00
MAN
-
SCL
1 stop19h 45m
Multiple Airlines
Mon 25/505:57
SCL
-
MAN
2 stops47h 13m
Multiple Airlines
Deal found 12/3£868
Sat 2/510:55
MAN
-
SCL
1 stop25h 55m
Air France
Sat 23/510:10
SCL
-
MAN
1 stop18h 50m
Air France
Deal found 15/3£890
Wed 29/409:30
MAN
-
SCL
1 stop26h 55m
Iberia
Mon 18/510:40
SCL
-
MAN
1 stop17h 10m
Iberia
Deal found 11/3£901
Sat 2/513:45
MAN
-
SCL
2 stops23h 05m
Multiple Airlines
Sat 23/510:10
SCL
-
MAN
1 stop18h 50m
Multiple Airlines
Deal found 15/3£913
Wed 9/917:50
MAN
-
SCL
1 stop18h 00m
Air France
Wed 23/921:15
SCL
-
MAN
1 stop21h 05m
Air France
Deal found 12/3£917

Find flight deals from Manchester to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 March 2026.

Round-trip from

£818

One-way from

£373

Popular in

December

Cheapest in

June

Average price

£1,013
Turkish Airlines
  • Turkish Airlines
  • 6/7-20/9
  • 4 total stops
  • 82h 50m total
  • Manchester to Santiago
19/4
  • 19/4
  • 2 total stops
  • 39h 40m total
  • Manchester to Santiago
Highest demand for flights based on searches. 9% potential increase in price (£86 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£20 potential savings vs. average return price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 March 2026.
Use the filters below to find and compare flights from Manchester to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 2/5

10:55-07:50

1 stop25h 55m

Santiago Arturo Merino Benitez

Sat 23/5

10:10-10:00

1 stop18h 50m

£890
Fastest return journey

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 2/5

13:45-07:50

2 stops23h 05m

Santiago Arturo Merino Benitez

Sat 23/5

10:10-10:00

1 stop18h 50m

£913

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sun 26/4

05:50-07:15

2 stops30h 25m

Santiago Arturo Merino Benitez

Sun 3/5

20:40-14:00

2 stops36h 20m

£968

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Fri 19/6

13:10-08:30

2 stops24h 20m

Santiago Arturo Merino Benitez

Sat 4/7

10:15-12:05

2 stops44h 50m

£984

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 16/5

13:45-07:50

2 stops23h 05m

Santiago Arturo Merino Benitez

Sat 30/5

10:10-10:00

1 stop18h 50m

£1,107

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 16/5

13:45-07:50

2 stops23h 05m

Santiago Arturo Merino Benitez

Sat 30/5

10:10-10:10

2 stops19h 00m

£1,144

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Thu 13/8

06:55-07:30

1 stop29h 35m

Santiago Arturo Merino Benitez

Tue 1/9

15:00-13:05

1 stop17h 05m

£1,197

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Fri 3/4

13:45-08:15

2 stops22h 30m

Santiago Arturo Merino Benitez

Sat 2/5

20:40-10:00

2 stops32h 20m

£1,210

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 15/8

18:10-07:45

1 stop18h 35m

Santiago Arturo Merino Benitez

Wed 2/9

10:40-19:05

2 stops27h 25m

£1,236

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 15/8

13:10-08:30

2 stops48h 20m

Santiago Arturo Merino Benitez

Thu 3/9

10:15-12:05

2 stops44h 50m

£1,242

Flights are sorted by cheapest return flights first.

Deals found on 11/3

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Santiago

How far ahead should I book a flight from Manchester to Santiago?

Use this chart to determine the optimal time to book a return flight from Manchester to Santiago. Price data was last updated on 13 March 2026.

Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Manchester to Santiago?

Currently, December is the cheapest month in which you can book a flight from Manchester to Santiago (average of £362). Flying from Manchester to Santiago in July is currently the most expensive (average of £981). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 15 March 2026.
Read reviews from past customers who have flown with Delta,Air France, andIberia from Manchester to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Related info for your journey

Find useful and relevant information for your journey from Manchester to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Manchester to Santiago?

    Departing from Manchester to Santiago will take you 24h 20m. Manchester and Santiago are separated by a distance of 7251 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to Santiago round-trip?

    Our cheapest airline available from Manchester to Santiago is Delta. Our recent data shows that you can find tickets from as low as £696 on this airline. Additional options worth looking into are Air France and British Airways, starting at £764 and £791 round-trip. Delta is currently priced 32% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Manchester to Santiago one-way?

    The cheapet airlines for a one-way flight from Manchester to Santiago are Vueling (£348), Iberia (£577), and British Airways (£713).

  • Can I find deals for flights from Manchester to Santiago that include hotel bookings?

    Yes. In addition to deals on Manchester to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Santiago.

  • Can I find deals for business class flights from Manchester to Santiago?

    Yes. Cheapflights offers flight deals from Manchester to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Santiago?

    Currently, December is the cheapest month in which you can book a flight from Manchester to Santiago (average of £362). Flying from Manchester to Santiago in July is currently the most expensive (average of £981). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Manchester to Santiago

Discover the top 4 airlines that operate flights from Manchester to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 15 March 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest£696Average£924FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Air FranceCheapest£764Average£1,187FlexibilityNo cancel feeOn-time77%
Search Air France flights
British AirwaysCheapest£791Average£1,051FlexibilityNo cancel feeOn-time70%
Search British Airways flights
IberiaCheapest£858Average£1,122FlexibilityNo cancel feeOn-time77%
Search Iberia flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Santiago?

Cheapflights helps you search for flights from Manchester to Santiago via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Santiago?

Cheapflights helps you find that perfect flight to Santiago from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Santiago with no change fees?

Yes, we can. To see specific flights from Manchester to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Santiago become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Santiago on Cheapflights with our Price Alert feature and get notified when better prices are available.

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