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Cheap flights from Manchester to Santiago from £258

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — SCL
11 May — 18 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Santiago
Explore the most affordable flight options available from Manchester to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 April 2026.

Tue 1/914:55
MAN
-
SCL
1 stop33h 05m
Air France
Tue 29/910:10
SCL
-
MAN
1 stop19h 50m
Air France
Deal found 7/4£823
Sat 20/613:10
MAN
-
SCL
3 stops44h 53m
Multiple Airlines
Wed 5/811:22
SCL
-
MAN
2 stops48h 08m
Multiple Airlines
Deal found 9/4£837
Tue 16/623:30
MAN
-
SCL
2 stops52h 56m
Multiple Airlines
Fri 3/711:22
SCL
-
MAN
2 stops43h 43m
Multiple Airlines
Deal found 7/4£844
Sat 20/617:35
MAN
-
SCL
2 stops43h 55m
Turkish Airlines
Wed 5/810:15
SCL
-
MAN
2 stops31h 10m
Turkish Airlines
Deal found 9/4£848
Wed 1/713:10
MAN
-
SCL
2 stops48h 20m
Multiple Airlines
Sun 12/711:22
SCL
-
MAN
2 stops48h 08m
Multiple Airlines
Deal found 7/4£851
Fri 13/1117:35
MAN
-
SCL
1 stop19h 35m
Multiple Airlines
Sat 28/1111:55
SCL
-
MAN
1 stop21h 20m
Multiple Airlines
Deal found 6/4£854
Tue 1/914:55
MAN
-
SCL
1 stop33h 05m
Multiple Airlines
Tue 29/910:10
SCL
-
MAN
2 stops20h 10m
Multiple Airlines
Deal found 7/4£864
Fri 11/913:10
MAN
-
SCL
2 stops48h 20m
Turkish Airlines
Fri 25/911:15
SCL
-
MAN
2 stops44h 50m
Turkish Airlines
Deal found 6/4£866
Fri 11/917:50
MAN
-
SCL
1 stop29h 10m
Air France
Fri 25/910:10
SCL
-
MAN
1 stop19h 50m
Air France
Deal found 8/4£867
Tue 1/920:50
MAN
-
SCL
2 stops27h 10m
KLM
Tue 29/911:10
SCL
-
MAN
2 stops19h 10m
KLM
Deal found 7/4£878

Find flight deals from Manchester to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 April 2026.

Round-trip from

£823

One-way from

£258

Popular in

December

Cheapest in

May

Average price

£936
Air France
  • Air France
  • 1/9-29/9
  • 2 total stops
  • 52h 55m total
  • Manchester to Santiago
Search Deals
19/4
  • 19/4
  • 2 total stops
  • 38h 20m total
  • Manchester to Santiago
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£66 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 April 2026.
Use the filters below to find and compare flights from Manchester to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Thu 18/6

13:10-05:03

3 stops44h 53m

Santiago Arturo Merino Benitez

Sat 4/7

02:27-12:05

2 stops52h 38m

£905
Fastest return journey

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Fri 11/9

17:50-19:00

1 stop29h 10m

Santiago Arturo Merino Benitez

Fri 25/9

10:10-10:20

2 stops20h 10m

£908

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Thu 18/6

17:35-05:03

3 stops40h 28m

Santiago Arturo Merino Benitez

Mon 6/7

09:15-09:35

3 stops43h 20m

£949

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Tue 1/9

23:30-04:59

3 stops34h 29m

Santiago Arturo Merino Benitez

Tue 29/9

11:15-12:05

2 stops44h 50m

£956

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 27/6

23:30-05:03

3 stops34h 33m

Santiago Arturo Merino Benitez

Fri 10/7

00:06-22:25

2 stops41h 19m

£984

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Thu 18/6

23:30-05:03

3 stops34h 33m

Santiago Arturo Merino Benitez

Sun 5/7

10:15-16:30

2 stops49h 15m

£991
Cheapest one-way

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Tue 21/4

19:40-04:45

2 stops38h 05m

£259

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 9/5

18:20-04:45

2 stops39h 25m

£263
Fastest single journey

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Wed 22/4

18:00-08:45

1 stop19h 45m

£295

ManchesterSantiago

MAN - SCL

MANSCL

Manchester

Sat 18/4

16:50-23:20

3 stops35h 30m

£333

Flights are sorted by cheapest return flights first.

Deals found on 6/4

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Santiago

How far ahead should I book a flight from Manchester to Santiago?

Use this chart to determine the optimal time to book a return flight from Manchester to Santiago. Price data was last updated on 10 April 2026.

Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Manchester to Santiago?

Currently, December is the cheapest month in which you can book a flight from Manchester to Santiago (average of £356). Flying from Manchester to Santiago in November is currently the most expensive (average of £845). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 11 April 2026.
Read reviews from past customers who have flown with Delta,Air France, andIberia from Manchester to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,406 reviews
Check prices

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
Delta
7.9
Good
8,406 reviews
Delta
7.9
Good
8,406 reviews
Check prices

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
Air France
7.4
Good
1,565 reviews
Delta
7.9
Good
8,406 reviews
Check prices

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
Iberia
7.0
Good
3,178 reviews
Delta
7.9
Good
8,406 reviews
Check prices

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good
British Airways
6.7
Okay
7,872 reviews
Delta
7.9
Good
8,406 reviews
Check prices

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Colin,Sept 2024

LHR - BOS

Delta One is very poor quality seating for first class. On multiple trips pieces have come off the seat. Staff and food have been good

Related info for your journey

Find useful and relevant information for your journey from Manchester to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Santiago?

    Departing from Manchester to Santiago will take you 34h 29m. Manchester and Santiago are separated by a distance of 7251 mi.

  • What are the cheapest airlines flying from Manchester to Santiago round-trip?

    Our cheapest airline available from Manchester to Santiago is Delta. Our recent data shows that you can find tickets from as low as £685 on this airline. Additional options worth looking into are Air France and British Airways, starting at £752 and £799 round-trip. Delta is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Santiago that include hotel bookings?

    Yes. In addition to deals on Manchester to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Santiago.

  • Can I find deals for business class flights from Manchester to Santiago?

    Yes. Cheapflights offers flight deals from Manchester to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Santiago?

    Currently, December is the cheapest month in which you can book a flight from Manchester to Santiago (average of £356). Flying from Manchester to Santiago in November is currently the most expensive (average of £845). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Manchester to Santiago

Discover the top 4 airlines that operate flights from Manchester to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 April 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest£685Average£909FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Air FranceCheapest£752Average£1,170FlexibilityNo cancel feeOn-time77%
Search Air France flights
British AirwaysCheapest£799Average£1,053FlexibilityNo cancel feeOn-time70%
Search British Airways flights
IberiaCheapest£856Average£1,104FlexibilityNo cancel feeOn-time77%
Search Iberia flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Santiago?

Cheapflights helps you search for flights from Manchester to Santiago via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Santiago?

Cheapflights helps you find that perfect flight to Santiago from Manchester by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Manchester to Santiago with no change fees?

Yes, we can. To see specific flights from Manchester to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Manchester to Santiago become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Santiago on Cheapflights with our Price Alert feature and get notified when better prices are available.

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