Cheap flights from Manchester to São Tomé from £815
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — TMS
29 Nov — 6 Dec1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheap flight deals from Manchester to São Tomé
Enter your travel dates to find the best prices.
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Best
Cheapest flights from Manchester to São Tomé
Explore the most affordable flight options available from Manchester to São Tomé. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 October 2026.
Thu 31/1220:10 -
2 stops22h 45m
Wed 13/120:00 -
3 stops16h 00m
Deal found 28/10£1,264
Thu 31/1211:25 -
2 stops24h 10m
Sun 10/112:35 -
2 stops46h 05m
Deal found 28/10£1,267
Tue 29/1219:10 -
2 stops23h 05m
Wed 13/120:00 -
3 stops16h 00m
Deal found 28/10£1,435
Tue 29/1214:25 -
2 stops17h 55m
Sun 10/120:00 -
2 stops14h 40m
Deal found 28/10£1,504
Thu 31/1220:10 -
2 stops22h 45m
Sat 9/122:25 -
1 stop12h 15m
Deal found 28/10£1,582
Tue 29/1218:30 -
3 stops23h 00m
Tue 12/107:30 -
4 stops24h 50m
Deal found 28/10£1,909
Tue 29/1214:25 -
2 stops17h 55m
Sat 9/122:25 -
1 stop12h 15m
Deal found 28/10£1,924
Tue 29/1218:30 -
4 stops23h 00m
Thu 7/107:30 -
4 stops24h 50m
Deal found 28/10£2,260
Best flights from Manchester to São Tomé
Discover carefully curated flight deals from Manchester to São Tomé that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 30 October 2026.
Fri 22/119:15 -
1 stop22h 15m
Sat 13/222:25 -
1 stop14h 00m
Deal found 29/10£815
Tue 12/118:30 -
3 stops23h 00m
Tue 26/107:30 -
4 stops24h 50m
Deal found 27/10£1,806
Sat 16/105:45 -
1 stop11h 45m
Sun 24/120:00 -
1 stop14h 40m
Deal found 27/10£1,131
Sun 17/118:30 -
3 stops23h 00m
Tue 26/107:30 -
4 stops24h 50m
Deal found 27/10£1,806
Sun 17/118:30 -
3 stops23h 00m
Thu 21/107:30 -
4 stops24h 50m
Deal found 28/10£1,833
Tue 12/118:30 -
3 stops23h 00m
Thu 21/107:30 -
4 stops24h 50m
Deal found 27/10£1,837
Tue 19/118:30 -
3 stops23h 00m
Thu 21/107:30 -
4 stops24h 50m
Deal found 28/10£1,960
Find flight deals from Manchester to São Tomé
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to São Tomé (TMS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 October 2026.
Customise your flight search to find flights from Manchester to São Tomé that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated 30 October 2026.
Use the filters below to find and compare flights from Manchester to São Tomé that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Fri 22/1
19:15-17:30
1 stop22h 15m
Sao Tome Is
Sat 13/2
22:25-12:25
1 stop14h 00m
£815
Fastest return journey
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Sat 16/1
05:45-17:30
1 stop11h 45m
Sao Tome Is
Sun 24/1
20:00-10:40
1 stop14h 40m
£1,131
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Tue 12/1
18:30-17:30
3 stops23h 00m
Sao Tome Is
Tue 26/1
07:30-08:20
4 stops24h 50m
£1,806
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Sun 17/1
18:30-17:30
3 stops23h 00m
Sao Tome Is
Tue 26/1
07:30-08:20
4 stops24h 50m
£1,806
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Sun 17/1
18:30-17:30
3 stops23h 00m
Sao Tome Is
Thu 21/1
07:30-08:20
4 stops24h 50m
£1,833
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Tue 12/1
18:30-17:30
3 stops23h 00m
Sao Tome Is
Thu 21/1
07:30-08:20
4 stops24h 50m
£1,837
ManchesterSão Tomé
MAN Manchester - TMS Sao Tome Is
MANTMS
Manchester
Tue 19/1
18:30-17:30
3 stops23h 00m
Sao Tome Is
Thu 21/1
07:30-08:20
4 stops24h 50m
£1,960
Flights are sorted by cheapest return flights first.
Deals found on 29/10
Sorted by cheapest first
Best time to book a flight from Manchester to São Tomé
Have a flexible travel schedule? Discover the best time to fly to São Tomé from Manchester with our price prediction graph.
MAN-TMS
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing São Tomé
Get insights into the airlines that provide service to São Tomé. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to São Tomé. Reviews last updated 30 October 2026.
Check out reviews from past customers who have flown with TAP AIR PORTUGAL from Manchester to São Tomé to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.
Related info for your journey
Find useful and relevant information for your journey from Manchester to São Tomé. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Manchester to São Tomé?
Ethiopian Air can get you from Manchester to São Tomé in just under 23h. Your travel time can differ by up to . Manchester and São Tomé are separated by a distance of 3694 mi.
Can I find deals for flights from Manchester to São Tomé that include hotel bookings?
Yes. In addition to deals on Manchester to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Manchester to São Tomé?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to São Tomé.
Can I find deals for business class flights from Manchester to São Tomé?
Yes. Cheapflights offers flight deals from Manchester to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on 30 October 2026.
Explore flights to São Tomé departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 30 October 2026.
Discover the top airline that operate flights from Manchester to São Tomé. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated 30 October 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Manchester to São Tomé?
Cheapflights makes it easy to find Manchester to São Tomé flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.
Why should you use Cheapflights to find cheap flight tickets from Manchester to São Tomé?
Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to São Tomé for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.
Can Cheapflights find flights from Manchester to São Tomé with no change fees?
Certainly. Search results for flights to São Tomé from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Manchester to São Tomé become cheaper?
Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to São Tomé from Manchester today and book when prices fit your budget.
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