Cheap flights from Manchester to São Tomé from £815

MAN — TMS
29 Nov — 6 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to São Tomé

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to São Tomé

Thu 31/1220:10 -
2 stops22h 45m
Wed 13/120:00 -
3 stops16h 00m
Deal found 28/10£1,264
Thu 31/1211:25 -
2 stops24h 10m
Sun 10/112:35 -
2 stops46h 05m
Deal found 28/10£1,267
Tue 29/1219:10 -
2 stops23h 05m
Wed 13/120:00 -
3 stops16h 00m
Deal found 28/10£1,435
Tue 29/1214:25 -
2 stops17h 55m
Sun 10/120:00 -
2 stops14h 40m
Deal found 28/10£1,504
Thu 31/1220:10 -
2 stops22h 45m
Sat 9/122:25 -
1 stop12h 15m
Deal found 28/10£1,582
Tue 29/1218:30 -
3 stops23h 00m
Tue 12/107:30 -
4 stops24h 50m
Deal found 28/10£1,909
Tue 29/1214:25 -
2 stops17h 55m
Sat 9/122:25 -
1 stop12h 15m
Deal found 28/10£1,924
Tue 29/1218:30 -
4 stops23h 00m
Thu 7/107:30 -
4 stops24h 50m
Deal found 28/10£2,260

Find flight deals from Manchester to São Tomé

Round-trip from

£753
TAP AIR PORTUGAL
  • TAP AIR PORTUGAL
  • 12/1-27/1
  • 4 total stops
  • 32h 35m total
  • Manchester to São Tomé

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Manchester to São Tomé that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Fri 22/1

19:15-17:30

1 stop22h 15m

Sao Tome Is

Sat 13/2

22:25-12:25

1 stop14h 00m

£815
Fastest return journey

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Sat 16/1

05:45-17:30

1 stop11h 45m

Sao Tome Is

Sun 24/1

20:00-10:40

1 stop14h 40m

£1,131

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Tue 12/1

18:30-17:30

3 stops23h 00m

Sao Tome Is

Tue 26/1

07:30-08:20

4 stops24h 50m

£1,806

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Sun 17/1

18:30-17:30

3 stops23h 00m

Sao Tome Is

Tue 26/1

07:30-08:20

4 stops24h 50m

£1,806

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Sun 17/1

18:30-17:30

3 stops23h 00m

Sao Tome Is

Thu 21/1

07:30-08:20

4 stops24h 50m

£1,833

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Tue 12/1

18:30-17:30

3 stops23h 00m

Sao Tome Is

Thu 21/1

07:30-08:20

4 stops24h 50m

£1,837

ManchesterSão Tomé

MAN Manchester - TMS Sao Tome Is

MANTMS

Manchester

Tue 19/1

18:30-17:30

3 stops23h 00m

Sao Tome Is

Thu 21/1

07:30-08:20

4 stops24h 50m

£1,960

Flights are sorted by cheapest return flights first.

Deals found on 29/10

Sorted by cheapest first

Best time to book a flight from Manchester to São Tomé

Have a flexible travel schedule? Discover the best time to fly to São Tomé from Manchester with our price prediction graph.
Estimated return price

Reviews of airlines servicing São Tomé

Check out reviews from past customers who have flown with TAP AIR PORTUGAL from Manchester to São Tomé to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.4

Overall

7.2

Crew

7.8

Boarding

7.0

Food

6.3

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Bhairav,Jun 2026

LHR - LIS

Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.

Entertainment

6.4

Overall

7.2

Crew

7.8

Boarding

7.0

Food

6.3

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Bhairav,Jun 2026

LHR - LIS

Flew business. Uncomfortable seats and so so food and drink. Only thing attractive was the price.

Related info for your journey

  • How long is the flight from Manchester to São Tomé?

    Ethiopian Air can get you from Manchester to São Tomé in just under 23h. Your travel time can differ by up to . Manchester and São Tomé are separated by a distance of 3694 mi.

  • Can I find deals for flights from Manchester to São Tomé that include hotel bookings?

    Yes. In addition to deals on Manchester to São Tomé flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to São Tomé?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to São Tomé.

  • Can I find deals for business class flights from Manchester to São Tomé?

    Yes. Cheapflights offers flight deals from Manchester to São Tomé by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Manchester to São Tomé

Top airline flying from Manchester to São Tomé

AirlineCheapestAverageFlexibilityOn-time
TAP AIR PORTUGALCheapest£833Average£1,168FlexibilityNo cancel feeOn-timeN/A
Search TAP AIR PORTUGAL flights

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to São Tomé?

Cheapflights makes it easy to find Manchester to São Tomé flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Manchester to São Tomé?

Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to São Tomé for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Manchester to São Tomé with no change fees?

Certainly. Search results for flights to São Tomé from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to São Tomé become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to São Tomé from Manchester today and book when prices fit your budget.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.