Cheap flights from Southampton to South America from £290

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — BOG
27 Apr — 4 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to South America

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to South America
Explore the most affordable flight options available from Southampton to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 March 2026.

Tue 15/917:20
SOU
-
GRU
2 stops40h 20m
Delta
Fri 25/920:30
GRU
-
SOU
2 stops56h 05m
Delta
Deal found 28/3£880
Tue 25/818:05
SOU
-
GRU
2 stops39h 35m
Delta
Fri 11/922:50
GRU
-
SOU
2 stops29h 55m
Delta
Deal found 25/3£886
Mon 11/517:20
SOU
-
GIG
1 stop30h 25m
KLM
Mon 18/521:55
GIG
-
SOU
1 stop30h 40m
KLM
Deal found 27/3£941
Mon 11/519:20
SOU
-
GIG
3 stops29h 25m
Multiple Airlines
Mon 18/514:55
GIG
-
SOU
2 stops37h 40m
Multiple Airlines
Deal found 27/3£970
Tue 12/517:20
SOU
-
SCL
2 stops20h 25m
KLM
Tue 19/510:15
SCL
-
SOU
2 stops41h 20m
KLM
Deal found 28/3£993
Sun 23/817:30
SOU
-
GRU
2 stops40h 10m
Delta
Mon 7/920:30
GRU
-
SOU
2 stops40h 20m
Delta
Deal found 25/3£996
Sat 9/517:20
SOU
-
GIG
2 stops44h 55m
Delta
Sat 16/521:00
GIG
-
SOU
2 stops39h 50m
Delta
Deal found 25/3£1,031
Fri 21/809:15
SOU
-
GRU
2 stops24h 25m
Delta
Mon 7/920:30
GRU
-
SOU
2 stops40h 20m
Delta
Deal found 25/3£1,046
Sat 9/517:20
SOU
-
GIG
1 stop30h 25m
KLM
Sat 16/521:55
GIG
-
SOU
1 stop30h 40m
KLM
Deal found 25/3£1,056
Tue 12/519:55
SOU
-
SCL
3 stops47h 20m
Multiple Airlines
Tue 19/510:15
SCL
-
SOU
2 stops41h 20m
Multiple Airlines
Deal found 28/3£1,062
Mon 27/409:05
SOU
-
GIG
1 stop14h 40m
KLM
Mon 4/521:55
GIG
-
SOU
1 stop30h 40m
KLM
Deal found 27/3£1,069
Fri 8/509:25
SOU
-
EZE
3 stops36h 56m
Multiple Airlines
Fri 15/504:45
EZE
-
SOU
3 stops34h 45m
Multiple Airlines
Deal found 23/3£1,079

Find flight deals from Southampton to South America

Keep the following information in mind while searching for Southampton to South America flight deals. Data was last updated 28 March 2026.

Round-trip from

£880

One-way from

£290

Popular in

December

Cheapest in

November

Average price

£743
Delta
  • Delta
  • 15/9-25/9
  • 4 total stops
  • 96h 25m total
  • Southampton to South America
9/5
  • 9/5
  • 3 total stops
  • 37h 40m total
  • Southampton to South America
Highest demand for flights based on searches. 1% potential increase in price (£8 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£13 potential savings vs. average return price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2026.
Use the filters below to find and compare flights from Southampton to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Tue 15/9

17:20-05:40

2 stops40h 20m

Sao Paulo Guarulhos Intl

Wed 30/9

22:50-16:50

2 stops38h 00m

£880

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Tue 15/9

17:20-05:40

2 stops40h 20m

Sao Paulo Guarulhos Intl

Fri 25/9

20:30-08:35

2 stops56h 05m

£880

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Tue 15/9

17:20-05:40

2 stops40h 20m

Sao Paulo Guarulhos Intl

Sun 27/9

22:50-08:35

2 stops29h 45m

£880

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Tue 15/9

09:05-05:40

2 stops48h 35m

Sao Paulo Guarulhos Intl

Sat 26/9

22:50-16:50

2 stops38h 00m

£880

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Tue 25/8

18:05-05:40

2 stops39h 35m

Sao Paulo Guarulhos Intl

Thu 10/9

20:30-16:50

2 stops40h 20m

£886

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Thu 27/8

09:15-05:40

2 stops24h 25m

Sao Paulo Guarulhos Intl

Fri 11/9

22:50-08:45

2 stops29h 55m

£886

SouthamptonRio de Janeiro

SOU - GIG

SOUGIG

Southampton Eastleigh

Mon 11/5

19:20-20:45

3 stops29h 25m

Rio de Janeiro–Galeão Intl

Mon 18/5

14:55-08:35

2 stops37h 40m

£970

SouthamptonSantiago

SOU - SCL

SOUSCL

Southampton Eastleigh

Tue 12/5

17:20-08:45

2 stops20h 25m

Santiago Arturo Merino Benitez

Tue 19/5

10:15-08:35

2 stops41h 20m

£993

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Sun 23/8

17:30-05:40

2 stops40h 10m

Sao Paulo Guarulhos Intl

Thu 10/9

20:30-16:50

2 stops40h 20m

£996

SouthamptonRio de Janeiro

SOU - GIG

SOUGIG

Southampton Eastleigh

Mon 11/5

09:05-23:10

2 stops18h 05m

Rio de Janeiro–Galeão Intl

Mon 18/5

14:55-08:35

2 stops37h 40m

£1,003

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from Southampton to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to South America

What is the cheapest month to book a flight from Southampton to South America?

Currently, April is the cheapest month in which you can book a flight from Southampton to South America (average of £74). Flying from Southampton to South America in December is currently the most expensive (average of £630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated 28 March 2026.
See what other customers who have flown with KLM from Southampton to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.6

Boarding

7.8

Food

7.3

Entertainment

7.1

Crew

8.4

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Comfort

7.6

Boarding

7.8

Food

7.3

Entertainment

7.1

Crew

8.4

Overall

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Southampton to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Southampton to South America?

    Located just 3.5 mi from the city center, Southampton Eastleigh (SOU) is the airport most travelers will use when flying to South America from Southampton.

  • How long is the flight from Southampton to South America?

    Airlines like Delta and KLM fly from Southampton to South America in about 20h 25m. The time it takes to get you to your destination can typically vary by up to 19h 55m. The distance between Southampton and South America is about 7183 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Southampton to South America?

  • Can I find deals for flights from Southampton to South America that include hotel bookings?

    Yes. In addition to deals on Southampton to South America flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to South America.

  • Can I find deals for business class flights from Southampton to South America?

    Yes. Cheapflights offers flight deals from Southampton to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to South America?

    Currently, April is the cheapest month in which you can book a flight from Southampton to South America (average of £74). Flying from Southampton to South America in December is currently the most expensive (average of £630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Southampton to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Southampton to South America

Discover the top airline that operate flights from Southampton to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest£1,208Average£1,342FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to South America?

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Why should you use Cheapflights to find cheap flight tickets from Southampton to South America?

Cheapflights helps you find that perfect flight to South America from Southampton by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Southampton to South America with no change fees?

Yes, we can. To see specific flights from Southampton to South America with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Southampton to South America become cheaper?

Not ready to book yet? You can track prices for flights from Southampton to South America on Cheapflights with our Price Alert feature and get notified when better prices are available.

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