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Cheap flights from Manchester to South Carolina from £264

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
11 Jan — 18 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 December 2025.

Thu 11/1210:25MAN - CLT
1 stop14h 35mMultiple Airlines
Thu 18/1214:22CLT - MAN
1 stop12h 33mMultiple Airlines
Deal found 10/12£993
Mon 15/1206:25MAN - GSP
2 stops22h 34mLufthansa
Wed 7/114:55GSP - MAN
2 stops21h 00mLufthansa
Deal found 11/12£1,138
Mon 15/1213:00MAN - GSP
2 stops27h 15mDelta
Wed 7/117:12GSP - MAN
1 stop12h 18mDelta
Deal found 11/12£1,157
Thu 11/1213:30MAN - CLT
1 stop15h 12mVirgin Atlantic
Thu 18/1211:38CLT - MAN
2 stops15h 17mVirgin Atlantic
Deal found 10/12£1,228
Thu 11/1209:45MAN - CLT
2 stops16h 59mBritish Airways
Thu 18/1218:13CLT - MAN
2 stops15h 07mBritish Airways
Deal found 10/12£1,229
Sat 20/1219:20MAN - CLT
3 stops30h 37mMultiple Airlines
Fri 26/1218:50CLT - MAN
2 stops24h 35mMultiple Airlines
Deal found 11/12£1,249
Mon 15/1206:25MAN - GSP
2 stops22h 34mLufthansa
Tue 30/1211:55GSP - MAN
2 stops21h 55mLufthansa
Deal found 11/12£1,373
Mon 15/1213:00MAN - GSP
2 stops27h 15mDelta
Tue 30/1210:05GSP - MAN
1 stop19h 25mDelta
Deal found 11/12£1,388
Sat 20/1209:50MAN - CLT
2 stops16h 21mAmerican Airlines
Fri 26/1223:00CLT - MAN
1 stop12h 35mAmerican Airlines
Deal found 11/12£1,470
Sat 20/1209:50MAN - CLT
2 stops17h 05mBritish Airways
Fri 26/1218:00CLT - MAN
2 stops12h 55mBritish Airways
Deal found 11/12£1,494
Sat 20/1206:45MAN - CLT
1 stop15h 10mLufthansa
Fri 26/1218:50CLT - MAN
1 stop23h 30mLufthansa
Deal found 11/12£1,589
Sat 20/1215:40MAN - CLT
2 stops33h 05mAer Lingus
Sun 4/114:52CLT - MAN
2 stops19h 28mAer Lingus
Deal found 11/12£1,618

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 12 December 2025.

Round-trip from

£509

One-way from

£264

Popular in

August

Cheapest in

February

Average price

£896
26/1-2/2
  • 26/1-2/2
  • 4 total stops
  • 37h 43m total
  • Manchester to South Carolina
Search Deals
25/2
  • 25/2
  • 3 total stops
  • 49h 25m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£50 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 12 December 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Mon 26/1

11:55-23:59

2 stops17h 04m

Charlotte Douglas

Mon 2/2

09:06-10:45

2 stops20h 39m

£509

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Mon 12/1

09:15-23:59

3 stops43h 44m

Charlotte Douglas

Mon 26/1

19:43-10:45

3 stops34h 02m

£518

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 25/1

06:20-16:55

2 stops15h 35m

Charlotte Douglas

Sun 1/2

18:50-16:20

2 stops16h 30m

£537

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 20/3

20:55-23:53

2 stops30h 58m

Charlotte Douglas

Wed 25/3

09:21-12:15

2 stops22h 54m

£542

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Fri 24/4

12:45-21:30

2 stops37h 45m

Savannah/Hilton Head

Fri 8/5

07:25-10:00

2 stops21h 35m

£685

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

07:05-19:03

2 stops16h 58m

Charleston

Thu 14/5

11:17-09:45

2 stops17h 28m

£691

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

10:55-20:39

2 stops14h 44m

Charleston

Thu 14/5

16:29-11:35

2 stops14h 06m

£691

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Sun 25/1

06:25-09:03

3 stops31h 38m

Myrtle Beach Intl

Sun 1/2

10:00-09:35

3 stops18h 35m

£695

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Mon 26/1

06:00-21:36

2 stops20h 36m

Savannah/Hilton Head

Mon 2/2

14:05-17:00

2 stops21h 55m

£697

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

11:00-23:51

1 stop17h 51m

Charleston

Thu 14/5

14:25-08:10

1 stop12h 45m

£698

Flights are sorted by cheapest return flights first.

Deals found on 11/12

Showing 1-10 of 53 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £522). Flying from Manchester to South Carolina in June is currently the most expensive (average of £630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 12 December 2025.

It’s typically best to fly out from Manchester to South Carolina at midday. Doing so could potentially save you 16% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 12 December 2025.
See what other customers who have flown with Delta, KLM, andFinnair from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews
Check prices

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews
Check prices

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,432 reviews
Delta
7.9
Good
8,009 reviews
Check prices

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Finnair
7.6
Good
1,334 reviews
Delta
7.9
Good
8,009 reviews
Check prices

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
675 reviews
Delta
7.9
Good
8,009 reviews
Check prices

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,571 reviews
Delta
7.9
Good
8,009 reviews
Check prices

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Scandinavian Airlines, British Airways, and United Airlines can get you from Manchester to South Carolina in just under 16h 58m. Your travel time can differ by up to 20h 47m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Charleston or Manchester - Myrtle Beach Intl, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £522). Flying from Manchester to South Carolina in June is currently the most expensive (average of £630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Manchester to South Carolina

Discover the top 6 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 12 December 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£513Average£633FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£544Average£706FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£567Average£725FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£581Average£739FlexibilityNo cancel feeOn-time75%
Search KLM flights
DeltaCheapest£624Average£770FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£803Average£966FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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