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Cheap flights from Manchester to St. Louis from £407

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
6 abr. — 13 abr.1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 7 marzo 2026.

mié. 18/1112:10
MAN
-
STL
2 stops16h 19m
British Airways
lun. 23/1116:48
STL
-
MAN
2 stops15h 12m
British Airways
Deal found 2/3£601
mié. 18/1113:30
MAN
-
STL
1 stop24h 42m
Multiple Airlines
lun. 23/1115:23
STL
-
MAN
2 stops16h 37m
Multiple Airlines
Deal found 2/3£613
vie. 11/906:55
MAN
-
STL
1 stop18h 35m
British Airways
lun. 14/916:47
STL
-
MAN
2 stops14h 23m
British Airways
Deal found 3/3£657
dom. 19/420:45
MAN
-
STL
2 stops32h 28m
Virgin Atlantic
dom. 26/418:50
STL
-
MAN
1 stop32h 00m
Virgin Atlantic
Deal found 5/3£660
jue. 3/906:55
MAN
-
STL
2 stops19h 24m
British Airways
mié. 9/916:47
STL
-
MAN
2 stops16h 43m
British Airways
Deal found 4/3£660
dom. 19/420:00
MAN
-
STL
2 stops27h 21m
British Airways
dom. 26/412:27
STL
-
MAN
2 stops15h 28m
British Airways
Deal found 5/3£662

Find flight deals from Manchester to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 7 marzo 2026.

Round-trip from

£660

One-way from

£407

Popular in

August

Cheapest in

December

Average price

£794
Virgin Atlantic
  • Virgin Atlantic
  • 19/4-26/4
  • 3 total stops
  • 64h 28m total
  • Manchester to St. Louis
Search Deals
16/3
  • 16/3
  • 3 total stops
  • 44h 52m total
  • Manchester to St. Louis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£89 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 7 marzo 2026.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

dom. 19/4

20:45-23:13

2 stops32h 28m

Lambert-St Louis

dom. 26/4

18:50-08:50

1 stop32h 00m

£660

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

dom. 19/4

20:00-17:21

2 stops27h 21m

Lambert-St Louis

dom. 26/4

12:27-09:55

2 stops15h 28m

£662

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

vie. 17/4

13:00-23:36

1 stop16h 36m

Lambert-St Louis

vie. 24/4

12:23-08:25

2 stops14h 02m

£732

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

vie. 17/4

13:00-11:56

1 stop28h 56m

Lambert-St Louis

vie. 24/4

13:02-08:50

1 stop13h 48m

£749

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

jue. 9/4

13:00-23:58

1 stop16h 58m

Lambert-St Louis

jue. 23/4

13:02-10:00

2 stops14h 58m

£776

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

vie. 27/3

13:25-23:58

1 stop15h 33m

Lambert-St Louis

lun. 30/3

17:59-14:00

2 stops14h 01m

£956

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

vie. 27/3

09:05-23:58

2 stops19h 53m

Lambert-St Louis

lun. 30/3

09:45-10:00

2 stops18h 15m

£957

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

vie. 31/7

13:00-09:40

1 stop26h 40m

Lambert-St Louis

mar. 15/12

09:00-06:40

2 stops15h 40m

£960

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

sáb. 1/8

13:15-23:38

1 stop16h 23m

Lambert-St Louis

mié. 16/12

13:30-10:30

1 stop15h 00m

£960
Fastest return journey

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

vie. 31/7

13:00-20:49

1 stop13h 49m

Lambert-St Louis

mié. 16/12

11:51-06:40

2 stops12h 49m

£960

Flights are sorted by cheapest return flights first.

Deals found on 6/3

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

How far ahead should I book a flight from Manchester to St. Louis?

Use this chart to determine the optimal time to book a return flight from Manchester to St. Louis. Price data was last updated on 27 February 2026.

Booking 46 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to St. Louis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Manchester to St. Louis?

Currently, March is the cheapest month in which you can book a flight from Manchester to St. Louis (average of £530). Flying from Manchester to St. Louis in August is currently the most expensive (average of £815). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated 7 marzo 2026.
Get a feel of what it's like to fly with Virgin Atlantic, United Airlines, andAer Lingus from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Virgin Atlantic
7.5
Good
680 reviews
Check prices

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Virgin Atlantic
7.5
Good
680 reviews
Virgin Atlantic
7.5
Good
680 reviews
Check prices

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
United Airlines
7.4
Good
9,403 reviews
Virgin Atlantic
7.5
Good
680 reviews
Check prices

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Aer Lingus
7.2
Good
1,471 reviews
Virgin Atlantic
7.5
Good
680 reviews
Check prices

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
Lufthansa
6.8
Okay
7,833 reviews
Virgin Atlantic
7.5
Good
680 reviews
Check prices

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!
British Airways
6.7
Okay
7,777 reviews
Virgin Atlantic
7.5
Good
680 reviews
Check prices

Entertainment

7.6

Food

6.9

Boarding

7.7

Comfort

7.3

Crew

8.2

Overall

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to St. Louis?

    Airlines like Virgin Atlantic, British Airways, and KLM fly from Manchester to St. Louis in about 16h 36m. The time it takes to get you to your destination can typically vary by up to 15h 52m. There are 4061 mi between Manchester and St. Louis. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester to St. Louis round-trip?

    British Airways, at £556, was found to be the cheapest airline from Manchester to St. Louis.Alternate airlines flying return to your destination include Scandinavian Airlines and Delta. British Airways is currently priced 36% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

    Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

  • Can I find deals for business class flights from Manchester to St. Louis?

    Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to St. Louis?

    Currently, March is the cheapest month in which you can book a flight from Manchester to St. Louis (average of £530). Flying from Manchester to St. Louis in August is currently the most expensive (average of £815). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 8 airlines flying from Manchester to St. Louis

Discover the top 8 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 7 marzo 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£556Average£795FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Scandinavian AirlinesCheapest£596Average£699FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
DeltaCheapest£610Average£861FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Virgin AtlanticCheapest£659Average£885FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
United AirlinesCheapest£718Average£826FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£724Average£901FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
KLMCheapest£758Average£879FlexibilityNo cancel feeOn-time75%
Search KLM flights
Aer LingusCheapest£846Average£1,035FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to St. Louis?

Cheapflights makes it easy to find Manchester to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Manchester to St. Louis?

Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to St. Louis for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Manchester to St. Louis with no change fees?

Certainly. Search results for flights to St. Louis from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to St. Louis become cheaper?

Yes, Cheapflights offers price alerts on Manchester to St. Louis flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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